-
1
-
-
0037316031
-
Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains
-
Askenazi M., Driggers E.M., Holtzman D.A., Norman T.C., Iverson S., Zimmer D.P., Boers M.E., Blomquist P.R., Martinez E.J., Monreal A.W., Feibelman T.P., Mayorga M.E., Maxon M.E., Sykes K., Tobin J.V., Cordero E., Salama S.R., Trueheart J., Royer J.C., Madden K.T. Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains. Nat. Biotechnol. 2003, 21:150-156.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 150-156
-
-
Askenazi, M.1
Driggers, E.M.2
Holtzman, D.A.3
Norman, T.C.4
Iverson, S.5
Zimmer, D.P.6
Boers, M.E.7
Blomquist, P.R.8
Martinez, E.J.9
Monreal, A.W.10
Feibelman, T.P.11
Mayorga, M.E.12
Maxon, M.E.13
Sykes, K.14
Tobin, J.V.15
Cordero, E.16
Salama, S.R.17
Trueheart, J.18
Royer, J.C.19
Madden, K.T.20
more..
-
2
-
-
54849405130
-
Renaissance in antibacterial discovery from actinomycetes
-
Baltz R.H. Renaissance in antibacterial discovery from actinomycetes. Curr. Opin. Pharmacol. 2008, 8:557-563.
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 557-563
-
-
Baltz, R.H.1
-
3
-
-
33947308882
-
Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans
-
Bergmann S., Schumann J., Scherlach K., Lange C., Brakhage A.A., Hertweck C. Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans. Nat. Chem. Biol. 2007, 3:213-217.
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 213-217
-
-
Bergmann, S.1
Schumann, J.2
Scherlach, K.3
Lange, C.4
Brakhage, A.A.5
Hertweck, C.6
-
4
-
-
27544456830
-
The impact of bacterial genomics on natural product research
-
Bode H.B., Muller R. The impact of bacterial genomics on natural product research. Angew. Chem. Int. Ed. Engl. 2005, 44:6828-6846.
-
(2005)
Angew. Chem. Int. Ed. Engl.
, vol.44
, pp. 6828-6846
-
-
Bode, H.B.1
Muller, R.2
-
5
-
-
79951642419
-
Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins
-
Bunet R., Song L.J., Mendes M.V., Corre C., Hotel L., Rouhier N., Framboisier X., Leblond P., Challis G.L., Aigle B. Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins. J. Bacteriol. 2011, 193:1142-1153.
-
(2011)
J. Bacteriol.
, vol.193
, pp. 1142-1153
-
-
Bunet, R.1
Song, L.J.2
Mendes, M.V.3
Corre, C.4
Hotel, L.5
Rouhier, N.6
Framboisier, X.7
Leblond, P.8
Challis, G.L.9
Aigle, B.10
-
6
-
-
20444496509
-
Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase
-
Chen Y.H., Wang C.C., Greenwell L., Rix U., Hoffmeister D., Vining L.C., Rohr J., Yang K.Q. Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase. J. Biol. Chem. 2005, 280:22508-22514.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 22508-22514
-
-
Chen, Y.H.1
Wang, C.C.2
Greenwell, L.3
Rix, U.4
Hoffmeister, D.5
Vining, L.C.6
Rohr, J.7
Yang, K.Q.8
-
8
-
-
68149179629
-
New natural product biosynthetic chemistry discovered by genome mining
-
Corre C., Challis G.L. New natural product biosynthetic chemistry discovered by genome mining. Nat. Prod. Rep. 2009, 26:977-986.
-
(2009)
Nat. Prod. Rep.
, vol.26
, pp. 977-986
-
-
Corre, C.1
Challis, G.L.2
-
9
-
-
84876002671
-
Natural products: a continuing source of novel drug leads
-
Cragg G.M., Newman D.J. Natural products: a continuing source of novel drug leads. Biochim. Biophys. Acta 2013, 1830:3670-3695.
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, pp. 3670-3695
-
-
Cragg, G.M.1
Newman, D.J.2
-
10
-
-
84881009432
-
Towards a new science of secondary metabolism
-
Craney A., Ahmed S., Nodwell J. Towards a new science of secondary metabolism. J. Antibiot. 2013, 66:387-400.
-
(2013)
J. Antibiot.
, vol.66
, pp. 387-400
-
-
Craney, A.1
Ahmed, S.2
Nodwell, J.3
-
11
-
-
84895073143
-
Importance of microbial natural products and the need to revitalize their discovery
-
Demain A.L. Importance of microbial natural products and the need to revitalize their discovery. J. Ind. Microbiol. Biotechnol. 2013, 1-17.
-
(2013)
J. Ind. Microbiol. Biotechnol.
, pp. 1-17
-
-
Demain, A.L.1
-
12
-
-
0027174569
-
Production of a novel polyketide antibiotic, jadomycin B, by Streptomyces venezuelae following heat shock
-
Doull J.L., Ayer S.W., Singh A.K., Thibault P. Production of a novel polyketide antibiotic, jadomycin B, by Streptomyces venezuelae following heat shock. J. Antibiot. 1993, 46:869-871.
-
(1993)
J. Antibiot.
, vol.46
, pp. 869-871
-
-
Doull, J.L.1
Ayer, S.W.2
Singh, A.K.3
Thibault, P.4
-
13
-
-
0028236918
-
Conditions for the production of jadomycin B by Streptomyces venezuelae ISP5230: effects of heat shock, ethanol treatment and phage infection
-
Doull J.L., Singh A.K., Hoare M., Ayer S.W. Conditions for the production of jadomycin B by Streptomyces venezuelae ISP5230: effects of heat shock, ethanol treatment and phage infection. J. Ind. Microbiol. 1994, 13:120-125.
-
(1994)
J. Ind. Microbiol.
, vol.13
, pp. 120-125
-
-
Doull, J.L.1
Singh, A.K.2
Hoare, M.3
Ayer, S.W.4
-
14
-
-
84893507957
-
Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways
-
Gomez-Escribano J.P., Bibb M.J. Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways. J. Ind. Microbiol. Biotechnol. 2014, 41:425-431.
-
(2014)
J. Ind. Microbiol. Biotechnol.
, vol.41
, pp. 425-431
-
-
Gomez-Escribano, J.P.1
Bibb, M.J.2
-
15
-
-
77955343496
-
Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2)
-
Gottelt M., Kol S., Gomez-Escribano J.P., Bibb M., Takano E. Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2). Microbiology 2010, 156:2343-2353.
-
(2010)
Microbiology
, vol.156
, pp. 2343-2353
-
-
Gottelt, M.1
Kol, S.2
Gomez-Escribano, J.P.3
Bibb, M.4
Takano, E.5
-
17
-
-
0031014024
-
Cloning and heterologous expression of the entire gene clusters for PD 116740 from Streptomyces strain WP 4669 and tetrangulol and tetrangomycin from Streptomyces rimosus NRRL 3016
-
Hong S.T., Carney J.R., Gould S.J. Cloning and heterologous expression of the entire gene clusters for PD 116740 from Streptomyces strain WP 4669 and tetrangulol and tetrangomycin from Streptomyces rimosus NRRL 3016. J. Bacteriol. 1997, 179:470-476.
-
(1997)
J. Bacteriol.
, vol.179
, pp. 470-476
-
-
Hong, S.T.1
Carney, J.R.2
Gould, S.J.3
-
18
-
-
84895453461
-
Systems biology and biotechnology of Streptomyces species for the production of secondary metabolites
-
Hwang K.-S., Kim H.U., Charusanti P., Palsson B.Ø., Lee S.Y. Systems biology and biotechnology of Streptomyces species for the production of secondary metabolites. Biotechnol. Adv. 2014, 32:255-268.
-
(2014)
Biotechnol. Adv.
, vol.32
, pp. 255-268
-
-
Hwang, K.-S.1
Kim, H.U.2
Charusanti, P.3
Palsson, B.Ø.4
Lee, S.Y.5
-
19
-
-
0019972221
-
Biosynthesis of Vineomycin-A1 and Vineomycin-B2
-
Imamura N., Kakinuma K., Ikekawa N., Tanaka H., Omura S. Biosynthesis of Vineomycin-A1 and Vineomycin-B2. J. Antibiot. 1982, 35:602-608.
-
(1982)
J. Antibiot.
, vol.35
, pp. 602-608
-
-
Imamura, N.1
Kakinuma, K.2
Ikekawa, N.3
Tanaka, H.4
Omura, S.5
-
20
-
-
33746288629
-
Culture conditions improving the production of jadomycin B
-
Jakeman D.L., Graham C.L., Young W., Vining L.C. Culture conditions improving the production of jadomycin B. J. Ind. Microbiol. Biotechnol. 2006, 33:767-772.
-
(2006)
J. Ind. Microbiol. Biotechnol.
, vol.33
, pp. 767-772
-
-
Jakeman, D.L.1
Graham, C.L.2
Young, W.3
Vining, L.C.4
-
21
-
-
39149093384
-
Sequential action of two flavoenzymes, PgaE and PgaM, in angucycline biosynthesis: chemoenzymatic synthesis of gaudimycin C
-
Kallio P., Liu Z., Mäntsälä P., Niemi J., Metsä-Ketelä M. Sequential action of two flavoenzymes, PgaE and PgaM, in angucycline biosynthesis: chemoenzymatic synthesis of gaudimycin C. Chem. Biol. 2008, 15:157-166.
-
(2008)
Chem. Biol.
, vol.15
, pp. 157-166
-
-
Kallio, P.1
Liu, Z.2
Mäntsälä, P.3
Niemi, J.4
Metsä-Ketelä, M.5
-
22
-
-
79959274080
-
Flavoprotein hydroxylase PgaE catalyzes two consecutive oxygen-dependent tailoring reactions in angucycline biosynthesis
-
Kallio P., Patrikainen P., Suomela J.P., Mäntsälä P., Metsä-Ketelä M., Niemi J. Flavoprotein hydroxylase PgaE catalyzes two consecutive oxygen-dependent tailoring reactions in angucycline biosynthesis. Biochemistry 2011, 50:5535-5543.
-
(2011)
Biochemistry
, vol.50
, pp. 5535-5543
-
-
Kallio, P.1
Patrikainen, P.2
Suomela, J.P.3
Mäntsälä, P.4
Metsä-Ketelä, M.5
Niemi, J.6
-
23
-
-
80054865417
-
A mass spectrometry-guided genome mining approach for natural product peptidogenomics
-
Kersten R.D., Yang Y.L., Xu Y., Cimermancic P., Nam S.J., Fenical W., Fischbach M.A., Moore B.S., Dorrestein P.C. A mass spectrometry-guided genome mining approach for natural product peptidogenomics. Nat. Chem. Biol. 2011, 7:794-802.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 794-802
-
-
Kersten, R.D.1
Yang, Y.L.2
Xu, Y.3
Cimermancic, P.4
Nam, S.J.5
Fenical, W.6
Fischbach, M.A.7
Moore, B.S.8
Dorrestein, P.C.9
-
24
-
-
84855990581
-
Angucyclines: biosynthesis, mode-of-action, new natural products, and synthesis
-
Kharel M.K., Pahari P., Shepherd M.D., Tibrewal N., Nybo S.E., Shaaban K.A., Rohr J. Angucyclines: biosynthesis, mode-of-action, new natural products, and synthesis. Nat. Prod. Rep. 2012, 29:264-325.
-
(2012)
Nat. Prod. Rep.
, vol.29
, pp. 264-325
-
-
Kharel, M.K.1
Pahari, P.2
Shepherd, M.D.3
Tibrewal, N.4
Nybo, S.E.5
Shaaban, K.A.6
Rohr, J.7
-
25
-
-
0003869903
-
-
John Innes Foundation, Norwich
-
Kieser T., Bibb M.J., Buttner M.J., Chater K.F., Hopwood D.A. Practical Streptomyces Genetics 2000, John Innes Foundation, Norwich.
-
(2000)
Practical Streptomyces Genetics
-
-
Kieser, T.1
Bibb, M.J.2
Buttner, M.J.3
Chater, K.F.4
Hopwood, D.A.5
-
26
-
-
34548172398
-
Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis
-
Koskiniemi H., Metsä-Ketelä M., Dobritzsch D., Kallio P., Korhonen H., Mäntsälä P., Schneider G., Niemi J. Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis. J. Mol. Biol. 2007, 372:633-648.
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 633-648
-
-
Koskiniemi, H.1
Metsä-Ketelä, M.2
Dobritzsch, D.3
Kallio, P.4
Korhonen, H.5
Mäntsälä, P.6
Schneider, G.7
Niemi, J.8
-
27
-
-
79954997859
-
Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
-
Laureti L., Song L., Huang S., Corre C., Leblond P., Challis G.L., Aigle B. Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens. Proc. Natl. Acad. Sci. USA 2011, 108:6258-6263.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 6258-6263
-
-
Laureti, L.1
Song, L.2
Huang, S.3
Corre, C.4
Leblond, P.5
Challis, G.L.6
Aigle, B.7
-
28
-
-
77949363508
-
Closthioamide: an unprecedented polythioamide antibiotic from the strictly anaerobic bacterium Clostridium cellulolyticum
-
Lincke T., Behnken S., Ishida K., Roth M., Hertweck C. Closthioamide: an unprecedented polythioamide antibiotic from the strictly anaerobic bacterium Clostridium cellulolyticum. Angew. Chem. Int. Ed. Engl. 2010, 49:2011-2013.
-
(2010)
Angew. Chem. Int. Ed. Engl.
, vol.49
, pp. 2011-2013
-
-
Lincke, T.1
Behnken, S.2
Ishida, K.3
Roth, M.4
Hertweck, C.5
-
29
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
30
-
-
84890086658
-
Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster
-
Luo Y., Huang H., Liang J., Wang M., Lu L., Shao Z., Cobb R.E., Zhao H. Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster. Nat. Commun. 2013, 4:2894.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2894
-
-
Luo, Y.1
Huang, H.2
Liang, J.3
Wang, M.4
Lu, L.5
Shao, Z.6
Cobb, R.E.7
Zhao, H.8
-
31
-
-
0033851115
-
The chemical and biological versatility of riboflavin
-
Massey V. The chemical and biological versatility of riboflavin. Biochem. Soc. Trans. 2000, 28:283-296.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 283-296
-
-
Massey, V.1
-
32
-
-
4544352632
-
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64
-
Metsä-Ketelä M., Ylihonko K., Mäntsälä P. Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64. J. Antibiot. 2004, 57:502-510.
-
(2004)
J. Antibiot.
, vol.57
, pp. 502-510
-
-
Metsä-Ketelä, M.1
Ylihonko, K.2
Mäntsälä, P.3
-
33
-
-
70350722394
-
Genomic basis for natural product biosynthetic diversity in the actinomycetes
-
Nett M., Ikeda H., Moore B.S. Genomic basis for natural product biosynthetic diversity in the actinomycetes. Nat. Prod. Rep. 2009, 26:1362-1384.
-
(2009)
Nat. Prod. Rep.
, vol.26
, pp. 1362-1384
-
-
Nett, M.1
Ikeda, H.2
Moore, B.S.3
-
34
-
-
84897952067
-
Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074
-
Olano C., Garcia I., Gonzalez A., Rodriguez M., Rozas D., Rubio J., Sanchez-Hidalgo M., Brana A.F., Mendez C., Salas J.A. Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074. Microb. Biotechnol. 2014, 7:242-256.
-
(2014)
Microb. Biotechnol.
, vol.7
, pp. 242-256
-
-
Olano, C.1
Garcia, I.2
Gonzalez, A.3
Rodriguez, M.4
Rozas, D.5
Rubio, J.6
Sanchez-Hidalgo, M.7
Brana, A.F.8
Mendez, C.9
Salas, J.A.10
-
35
-
-
84893170608
-
Recent advances in the heterologous expression of microbial natural product biosynthetic pathways
-
Ongley S.E., Bian X., Neilan B.A., Muller R. Recent advances in the heterologous expression of microbial natural product biosynthetic pathways. Nat. Prod. Rep. 2013, 30:1121-1138.
-
(2013)
Nat. Prod. Rep.
, vol.30
, pp. 1121-1138
-
-
Ongley, S.E.1
Bian, X.2
Neilan, B.A.3
Muller, R.4
-
36
-
-
84856179567
-
Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis
-
Pahari P., Kharel M.K., Shepherd M.D., van Lanen S.G., Rohr J. Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis. Angew. Chem. Int. Ed. Engl. 2012, 51:1216-1220.
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 1216-1220
-
-
Pahari, P.1
Kharel, M.K.2
Shepherd, M.D.3
van Lanen, S.G.4
Rohr, J.5
-
37
-
-
34548707013
-
Artificial reconstruction of two cryptic angucycline antibiotic biosynthetic pathways
-
Palmu K., Ishida K., Mäntsälä P., Hertweck C., Metsä-Ketelä M. Artificial reconstruction of two cryptic angucycline antibiotic biosynthetic pathways. ChemBioChem 2007, 8:1577-1584.
-
(2007)
ChemBioChem
, vol.8
, pp. 1577-1584
-
-
Palmu, K.1
Ishida, K.2
Mäntsälä, P.3
Hertweck, C.4
Metsä-Ketelä, M.5
-
38
-
-
84861598935
-
Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities
-
Patrikainen P., Kallio P., Fan K., Klika K.D., Shaaban K.A., Mäntsälä P., Rohr J., Yang K., Niemi J., Metsä-Ketelä M. Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities. Chem. Biol. 2012, 19:647-655.
-
(2012)
Chem. Biol.
, vol.19
, pp. 647-655
-
-
Patrikainen, P.1
Kallio, P.2
Fan, K.3
Klika, K.D.4
Shaaban, K.A.5
Mäntsälä, P.6
Rohr, J.7
Yang, K.8
Niemi, J.9
Metsä-Ketelä, M.10
-
39
-
-
0037415047
-
Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU
-
Rix U., Remsing L.L., Hoffmeister D., Bechthold A., Rohr J. Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU. ChemBioChem 2003, 4:109-111.
-
(2003)
ChemBioChem
, vol.4
, pp. 109-111
-
-
Rix, U.1
Remsing, L.L.2
Hoffmeister, D.3
Bechthold, A.4
Rohr, J.5
-
40
-
-
64549150542
-
Triggering cryptic natural product biosynthesis in microorganisms
-
Scherlach K., Hertweck C. Triggering cryptic natural product biosynthesis in microorganisms. Org. Biomol. Chem. 2009, 7:1753-1760.
-
(2009)
Org. Biomol. Chem.
, vol.7
, pp. 1753-1760
-
-
Scherlach, K.1
Hertweck, C.2
-
41
-
-
70149109184
-
Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans
-
Schroeckh V., Scherlach K., Nützmann H.-W., Shelest E., Schmidt-Heck W., Schuemann J., Martin K., Hertweck C., Brakhage A.A. Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans. Proc. Natl. Acad. Sci. USA 2009, 106:14558-14563.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 14558-14563
-
-
Schroeckh, V.1
Scherlach, K.2
Nützmann, H.-W.3
Shelest, E.4
Schmidt-Heck, W.5
Schuemann, J.6
Martin, K.7
Hertweck, C.8
Brakhage, A.A.9
-
42
-
-
84901000640
-
High-throughput platform for the discovery of elicitors of silent bacterial gene clusters
-
Seyedsayamdost M.R. High-throughput platform for the discovery of elicitors of silent bacterial gene clusters. Proc. Natl. Acad. Sci. USA 2014, 111:7266-7271.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 7266-7271
-
-
Seyedsayamdost, M.R.1
-
43
-
-
84888617134
-
Discovery of a family of [gamma]-aminobutyrate ureas via rational derepression of a silent bacterial gene cluster
-
Sidda J.D., Song L., Poon V., Al-Bassam M., Lazos O., Buttner M.J., Challis G.L., Corre C. Discovery of a family of [gamma]-aminobutyrate ureas via rational derepression of a silent bacterial gene cluster. Chem. Sci. 2014, 5:86-89.
-
(2014)
Chem. Sci.
, vol.5
, pp. 86-89
-
-
Sidda, J.D.1
Song, L.2
Poon, V.3
Al-Bassam, M.4
Lazos, O.5
Buttner, M.J.6
Challis, G.L.7
Corre, C.8
-
44
-
-
16444371523
-
A chemoenzymatic, enantioconvergent, asymmetric total synthesis of (R)-Fridamycin E
-
Ueberbacher B.J., Osprian I., Mayer S.F., Faber K. A chemoenzymatic, enantioconvergent, asymmetric total synthesis of (R)-Fridamycin E. Eur. J. Org. Chem. 2005, 1266-1270.
-
(2005)
Eur. J. Org. Chem.
, pp. 1266-1270
-
-
Ueberbacher, B.J.1
Osprian, I.2
Mayer, S.F.3
Faber, K.4
-
45
-
-
0345839252
-
Where will new antibiotics come from?
-
Walsh C. Where will new antibiotics come from?. Nat. Rev. Microbiol. 2003, 1:65-70.
-
(2003)
Nat. Rev. Microbiol.
, vol.1
, pp. 65-70
-
-
Walsh, C.1
-
46
-
-
84879833139
-
An engineered strong promoter for streptomycetes
-
Wang W., Li X., Wang J., Xiang S., Feng X., Yang K. An engineered strong promoter for streptomycetes. Appl. Environ. Microbiol. 2013, 79:4484-4492.
-
(2013)
Appl. Environ. Microbiol.
, vol.79
, pp. 4484-4492
-
-
Wang, W.1
Li, X.2
Wang, J.3
Xiang, S.4
Feng, X.5
Yang, K.6
-
47
-
-
68049118544
-
Application of a double-reporter-guided mutant selection method to improve clavulanic acid production in Streptomyces clavuligerus
-
Xiang S.H., Li J., Yin H., Zheng J.T., Yang X., Wang H.B., Luo J.L., Bai H., Yang K.Q. Application of a double-reporter-guided mutant selection method to improve clavulanic acid production in Streptomyces clavuligerus. Metab. Eng. 2009, 11:310-318.
-
(2009)
Metab. Eng.
, vol.11
, pp. 310-318
-
-
Xiang, S.H.1
Li, J.2
Yin, H.3
Zheng, J.T.4
Yang, X.5
Wang, H.B.6
Luo, J.L.7
Bai, H.8
Yang, K.Q.9
-
48
-
-
84893456760
-
Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A
-
Yamanaka K., Reynolds K.A., Kersten R.D., Ryan K.S., Gonzalez D.J., Nizet V., Dorrestein P.C., Moore B.S. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proc. Natl. Acad. Sci. USA 2014, 111:1957-1962.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 1957-1962
-
-
Yamanaka, K.1
Reynolds, K.A.2
Kersten, R.D.3
Ryan, K.S.4
Gonzalez, D.J.5
Nizet, V.6
Dorrestein, P.C.7
Moore, B.S.8
-
49
-
-
0035965779
-
A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230
-
Yang K., Han L., He J., Wang L., Vining L.C. A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230. Gene 2001, 279:165-173.
-
(2001)
Gene
, vol.279
, pp. 165-173
-
-
Yang, K.1
Han, L.2
He, J.3
Wang, L.4
Vining, L.C.5
-
50
-
-
84895073357
-
Activating secondary metabolism with stress and chemicals
-
Yoon V., Nodwell J.R. Activating secondary metabolism with stress and chemicals. J. Ind. Microbiol. Biotechnol. 2014, 41:415-424.
-
(2014)
J. Ind. Microbiol. Biotechnol.
, vol.41
, pp. 415-424
-
-
Yoon, V.1
Nodwell, J.R.2
-
51
-
-
65549083361
-
Strategies for the discovery of new natural products by genome mining
-
Zerikly M., Challis G.L. Strategies for the discovery of new natural products by genome mining. ChemBioChem 2009, 10:625-633.
-
(2009)
ChemBioChem
, vol.10
, pp. 625-633
-
-
Zerikly, M.1
Challis, G.L.2
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