Catalytic, asymmetric, and stereodivergent synthesis of non-symmetric β,β-Diaryl-α-Amino Acids

Journal of the American Chemical Society

Volumn 137, Issue 2, 2015, Pages 999-1006

  Molinaro, Carmela ^a   Scott, Jeremy P ^b   Shevlin, Michael ^a   Wise, Christopher ^b   Ménard, Alain ^a   Gibb, Andrew ^b   Junker, Ellyn M ^b   Lieberman, David ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Merck Sharp & Dohme Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL REACTIONS; ENANTIOSELECTIVITY; HYDROGENATION; STEREOCHEMISTRY; STEREOSELECTIVITY; SULFUR COMPOUNDS;

ASYMMETRIC HYDROGENATION; DIASTEREOSELECTIVE; ENANTIOSELECTIVE HYDROGENATION; STEREODIVERGENT SYNTHESIS; STEREOGENIC CENTERS; SUBSTITUTED GROUPS; SUZUKI-MIYAURA CROSS-COUPLING; TETRASUBSTITUTED OLEFINS;

AMINO ACIDS;

ACRYLIC ACID; AMINO ACID DERIVATIVE; TOLUENESULFONIC ACID DERIVATIVE; AMINO ACID;

ALKYLATION; ARTICLE; CATALYSIS; CHIRALITY; CHROMATOGRAPHY; CRYSTALLIZATION; DECHLORINATION; ENANTIOSELECTIVITY; HYDROGENATION; ISOMERIZATION; REDUCTION; STEREOCHEMISTRY; STEREOISOMERISM; SUBSTITUTION REACTION; SUZUKI REACTION; SYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ENZYME SPECIFICITY;

AMINO ACIDS; CATALYSIS; CHEMISTRY TECHNIQUES, SYNTHETIC; HYDROGENATION; MODELS, MOLECULAR; MOLECULAR CONFORMATION; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 84921452781     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja511872a     Document Type: Article

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