Curcumin and its major metabolites inhibit the inflammatory response induced by lipopolysaccharide: Translocation of nuclear factor-κB as potential target

Molecular Medicine Reports

Volumn 11, Issue 4, 2015, Pages 3087-3093

  Zhao, Feng ^a   Gong, Yudian ^b   Hu, Yuan ^a   Lu, Minghui ^a   Wang, Jing ^a   Dong, Jianxin ^a   Chen, Daquan ^a   Chen, Lei ^a   Fu, Fenghua ^a   Qiu, Feng ^c  

^a YANTAI UNIVERSITY   (China)

^b Yantai Psychological Rehabilitation Hospital   (China)

^c SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Curcumin; Cyclooxygenase 2; Inducible nitric oxide synthase; Metabolite; Nuclear factor B

Indexed keywords

CURCUMIN; CYCLOOXYGENASE 2; CYTOPLASM PROTEIN; DRUG METABOLITE; HEXAHYDROCURCUMIN; HYDROCORTISONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRITE; NUCLEAR PROTEIN; OCTAHYDROCURCUMIN; TETRAHYDROCURCUMIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL CELL; ANIMAL CELL CULTURE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; MACROPHAGE; MOUSE; MTT ASSAY; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; MALE; METABOLISM; PROTEIN TRANSPORT; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CELL SURVIVAL; CURCUMIN; CYCLOOXYGENASE 2; CYTOKINES; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN TRANSPORT; PROTEOLYSIS; RATS;

EID: 84921415749     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.3079     Document Type: Article

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