In vitro anti-inflammatory effects of beta-carboline alkaloids, isolated from picrasma quassioides, through inhibition of the iNOS pathway

Planta Medica

Volumn 78, Issue 18, 2012, Pages 1906-1911

  Zhao, Feng ^a   Gao, Zhiting ^a   Jiao, Weihua ^b,c   Chen, Liping ^a   Chen, Lei ^a   Yao, Xinsheng ^b  

^a YANTAI UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

carboline alkaloids; anti inflammatory effect; iNOS; macrophage; nitric oxide; Picrasma quassioides; Simarubaceae

Indexed keywords

6 METHOXY 3 VINYL BETA CARBOLINE; 6,12 DIMETHOXY 3 VINYL BETA CARBOLINE; BETA CARBOLINE DERIVATIVE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; NITRIC OXIDE; QUASSIDINE F; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALORIMETRY; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUOROMETRY; IN VITRO STUDY; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; PICRASMA; PICRASMA QUASSIOIDES; PROTEIN EXPRESSION; WESTERN BLOTTING;

ACTINS; ALKALOIDS; ANTI-INFLAMMATORY AGENTS; CARBOLINES; CELLS, CULTURED; CYCLOOXYGENASE 2; DRUGS, CHINESE HERBAL; HUMANS; INTERLEUKIN-3; INTERLEUKIN-6; MACROPHAGES; NITRIC OXIDE SYNTHASE TYPE II; PICRASMA;

PICRASMA QUASSIOIDES; SIMAROUBACEAE;

EID: 84871618304     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0032-1327883     Document Type: Article

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