Curcumin potentiates the antitumor effects of 5-FU in treatment of esophageal squamous carcinoma cells through downregulating the activation of NF-κB signaling pathway in vitro and in vivo

Acta Biochimica et Biophysica Sinica

Volumn 44, Issue 10, 2012, Pages 847-855

  Tian, Fang ^a   Fan, Tianli ^a   Zhang, Yan ^b   Jiang, Yanan ^a   Zhang, Xiaoyan ^a  

^a ZHENGZHOU UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

chemoprevention; curcumin; esophageal squamous cell carcinoma; NF B signaling pathway; nude mice

Indexed keywords

ANTINEOPLASTIC AGENT; CURCUMIN; CYCLIN D1; FLUOROURACIL; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; DRUG SCREENING; ESOPHAGUS TUMOR; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MOUSE; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE; TUMOR VOLUME; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CURCUMIN; CYCLIN D1; DOWN-REGULATION; DRUG SYNERGISM; ESOPHAGEAL NEOPLASMS; FLUOROURACIL; HUMANS; I-KAPPA B PROTEINS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NF-KAPPA B; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS MUSCULUS;

EID: 84867024772     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gms074     Document Type: Article

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