Effects of curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180

Planta Medica

Volumn 76, Issue 16, 2010, Pages 1866-1870

  Graber Maier, Angelika ^a   Berger Büter, Karin ^b   Aeschlimann, Julia ^a   Bittel, Claudia ^a   Kreuter, Matthias ^b   Drewe, Juergen ^a   Gutmann, Heike ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b Vitaplant Ltd   (Switzerland)

Author keywords

Curcuma longa L.; curcuminoids; cytochrome P450 3A4; LS180; Pglycoprotein; Zingiberaceae

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CURCUMA LONGA EXTRACT; CURCUMIN; CYTOCHROME P450 3A4; DEMETHOXYCURCUMIN; DIDEMETHOXYCURCUMIN; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1;

ARTICLE; CELL CULTURE; DOWN REGULATION; DRUG ABSORPTION; DRUG EFFECT; GENE EXPRESSION; INTESTINE CELL; PROTEIN EXPRESSION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION;

CELL LINE; CURCUMA; CURCUMIN; CYTOCHROME P-450 CYP3A; HERB-DRUG INTERACTIONS; HUMANS; INTESTINES; P-GLYCOPROTEIN; PLANT EXTRACTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

CURCUMA; CURCUMA LONGA; ZINGIBERACEAE;

EID: 78349260498     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0030-1249980     Document Type: Article

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