Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 31, Issue 2, 2009, Pages 89-93

  Nandal, Shivender ^a   Dhir, Ashish ^a   Kuhad, Anurag ^a   Sharma, Sameer ^a   Chopra, Kanwaljit ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Cotton pellet granuloma pouch model; Curcumin; Cyclooxygenase inhibitiors; TNF

Indexed keywords

ACETYLSALICYLIC ACID; CURCUMIN; CYCLOOXYGENASE 2; ROFECOXIB; TUMOR NECROSIS FACTOR ALPHA; CYCLOOXYGENASE 2 INHIBITOR; LACTONE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; SULFONE;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; COTTON PELLET GRANULOMA POUCH MODEL; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MODEL; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; RHIZOME; ANIMAL; DISEASE MODEL; GRANULOMA; METABOLISM; TRADITIONAL MEDICINE; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CURCUMIN; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; GRANULOMA; LACTONES; MALE; MEDICINE, TRADITIONAL; RATS; RATS, WISTAR; SULFONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 68349121770     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2009.31.2.1357705     Document Type: Article

References (36)

1. Gescher, A. Polyphenolic phytochemicals versus non-steroidal anti-inflammatory drugs: Which are better cancer chemopreventive agents? J Chemother 2004, 16(Suppl. 4): 3-6.
2. Kohli, K., Ali, J., Ansari, M.J., Raheman, Z. Curcumin: A natural anti-inflammatory agent. Ind J Pharm 2005, 37(3): 141-147
3. Reddy, B.S. Strategies for colon cancer prevention: Combination of chemopreventive agents. Subcell Biochem 2007, 42: 213-225
4. Han, C., Wang, L., Yu, K. et al. Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori. FEBS J 2006, 273(20): 4682-4692
5. Rema, M., Pradeepa, R. Diabetic retinopathy: An Indian perspective. Ind J Med Res 2007, 125(3): 297-310.
6. Arafa, H.M. Curcumin attenuates diet-induced hypercholesterolemia in rats. Med Sci Monit 2005, 11(7): BR228-34.
7. Dikshit, P., Goswami, A., Mishra, A., Chatterjee, M., Jana, N.R. Curcumin induces stress response, neurite outgrowth and prevents NF-kappaB activation by inhibiting the proteasome function. Neurotox Res 2006, 9(1): 29-37.
8. Osawa, T. Nephroprotective and hepatoprotective effects of curcuminoids. Adv Exp Med Biol 2007, 595: 407-423
9. Liu, J.P., Manheimer, E., Yang, M. Herbal medicines for treating HIV infection and AIDS. Cochrane Database Syst Rev 1995, (3): CD003937.
10. Tirkey, N., Kaur, G., Vij, G., Chopra, K. Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys. BMC Pharmacol 2005, 5: 15.
11. Sharma, S., Kulkarni, S.K., Agrewala, J.N., Chopra, K. Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain. Eur J Pharmacol 2006, 536(3): 256-261
12. Sharma, S., Chopra, K., Kulkarni, S.K. Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: Participation of nitric oxide and TNF-alpha. Phytother Res 2007, 21(3): 278-283
13. Sharma, S., Chopra, K., Kulkarni, S.K., Agrewala, J.N. Resveratrol and curcumin suppress immune response through CD28/CTLA-4 and CD80 costimulatory pathway. Clin Exp Immunol 2007, 147(1): 155-163
14. Biswas, S.K., McClure, D., Jimenez, L.A., Megson, I.L., Rahman, I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: Mechanism of free radical scavenging activity. Antioxid Redox Signal 2005, 7(1-2): 32-41.
15. Balasubramanyam, M., Koteswari, A.A., Kumar, R.S., Monickaraj, S.F., Maheswari, J.U., Mohan, V. Curcumin-induced inhibition of cellular reactive oxygen species generation: Novel therapeutic implications. J Biosci 2003, 28(6): 715-721
16. Kumar, V., Robbins, S.L. Basic Pathology. Istanbul Press: Istanbul 1995, 25-47.
17. Camacho-Barquero, L., Villegas, I., Sanchez-Calvo, J.M. et al. Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX- 2 and iNOS expression in chronic experimental colitis. Int Immunopharmacol 2007, 7(3): 333-342
18. Menon, V.P., Sudheer, A.R. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol 2007, 595: 105-125
19. Rao, C.V. Regulation of COX and LOX by curcumin. Adv Exp Med Biol 2007, 595: 213-226
20. Süleyman, H., Yyldyrym, D., Aslan, A., Göçer, F., Gepdiremen, A., Güvenalp, Z. An investigation of the antiinflammatory effects of an extract from Cladonia rangiformis HOFFM. Biol Pharm Bull 2002, 25(1): 10-13
21. Meier, R., Schuler, W., Desaulles, P. On the mechanism of cortisone inhibition of connective tissue proliferation. Experientia 1950, 6(12): 469-471
22. Ionac, M., Parnham, M.J., Plauchithiu, M., Brune, K. Oxaceprol, an atypical inhibitor of inflammation and joint damage. Pharmacol Res 1996, 33(6): 367-373
23. Loux, J.J., Smith, S., Salem, H. Anti-inflammatory activity: Evaluation of a new screening procedure. Inflammation 1977, 2(2): 125-130
24. Winter, C.A., Risley, E.A., Nuss, G.W. Anti-inflammatory and antipyretic activities of indomethacin, 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole- 3-acetic acid. J Pharmacol Exp Ther 1963, 141: 369-376
25. Süleyman, H., Demircan, B., Karagöz, Y., Oztasan, N., Süleyman, B. Antiinflammatory effects of selective COX-2 inhibitors. Pol J Pharmacol 2004, 56(6): 775-780
26. Sharma, S., Kulkarni, S.K., Chopra, K. Curcumin, the active principle of turmeric (Curcuma longa), ameliorates diabetic nephropathy in rats. Clin Exp Pharmacol Physiol 2006, 33(10): 940-945
27. Riahman, A., Biswas, S.K., KirleHan, P.A. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem Pharmacol 2006, 72(11): 1439-1452
28. Sugiyama, Y., Kawakishi, S., Osawa, T. Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin. Biochem Pharmacol 1996, 52(4): 519-525
29. Ruby, A.J., Kuttan, G., Babu, K.D., Rajasekharan, K.N., Kuttan, R. Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Lett 1995, 94(1): 79-83.
30. Adams, B.K., Cai, J., Armstrong, J. et al. EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism. Anticancer Drugs 2005, 16(3): 263-275
31. Reddy, B.S., Hirose, Y., Lubet, R. et al. Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. Cancer Res 2000, 60(2): 293-297
32. Olajide, O.A., Makinde, J.M., Awe, S.O. Effects of the aqueous extract of Bridelia ferruginea stem bark on carrageenan-induced oedema and granuloma tissue formation in rats and mice. Ethnopharmacol 1999, 66(1): 113-117
33. Olajide, O.A., Alada, A.R. Studies on the anti-inflammatory properties of Entada abyssinica. Fitoterapia 2001, 72(5): 492-496
34. Chainani-Wu, N. Safety and anti-inflammatory activity of curcumin: A component of tumeric (Curcuma longa). J Altern Complement Med 2003, 9(1): 161-168
35. Ligeiro de Oliveira, A.P., Domingos, H.V., Cavriani, G. et al. Cellular recruitment and cytokine generation in a rat model of allergic lung inflammation are differentially modulated by progesterone and estradiol. Am J Physiol Cell Physiol 2007, 293(3): C1120-8.
36. Park, H.J., Lee, P.H., Ahn, Y.W. et al. Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action. Eur J Neurosci 2007, 26(1): 79-89.