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Volumn 14, Issue 2, 2014, Pages 161-176

mRNA-based dendritic cell vaccines

Author keywords

cancer; cytotoxic T cell; dendritic cell; mRNA; tumor antigen

Indexed keywords

DENDRITIC CELL VACCINE; MESSENGER RNA; CANCER VACCINE; TUMOR ANTIGEN;

EID: 84921376995     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.2014.957684     Document Type: Review
Times cited : (134)

References (161)
  • 1
    • 84895901860 scopus 로고    scopus 로고
    • Global cancer patterns: Causes and prevention
    • Vineis P, Wild CP. Global cancer patterns: causes and prevention. Lancet 2014; 383(9916):549-57
    • (2014) Lancet , vol.383 , Issue.9916 , pp. 549-557
    • Vineis, P.1    Wild, C.P.2
  • 3
    • 4444243096 scopus 로고    scopus 로고
    • Tumor-specific shared antigenic peptides recognized by human T cells
    • Van Der Bruggen P, Zhang Y, Chaux P, et al. Tumor-specific shared antigenic peptides recognized by human T cells. Immunol Rev 2002;188:51-64
    • (2002) Immunol Rev , vol.188 , pp. 51-64
    • Van Der Bruggen, P.1    Zhang, Y.2    Chaux, P.3
  • 4
    • 84901405092 scopus 로고    scopus 로고
    • Clinical use of dendritic cells for cancer therapy
    • Anguille S, Smits EL, Lion E, et al. Clinical use of dendritic cells for cancer therapy. Lancet Oncol 2014;15(7):e257-67
    • (2014) Lancet Oncol , vol.15 , Issue.7 , pp. e257-e267
    • Anguille, S.1    Smits, E.L.2    Lion, E.3
  • 5
    • 84890254287 scopus 로고    scopus 로고
    • Trial watch: Dendritic cell-based interventions for cancer therapy
    • Vacchelli E, Vitale I, Eggermont A, et al. Trial watch: dendritic cell-based interventions for cancer therapy. Oncoimmunology 2013;2(10):e25771
    • (2013) Oncoimmunology , vol.2 , Issue.10 , pp. e25771
    • Vacchelli, E.1    Vitale, I.2    Eggermont, A.3
  • 6
    • 84890814629 scopus 로고    scopus 로고
    • Breakthrough of the year 2013. Cancer immunotherapy
    • Couzin-Frankel J. Breakthrough of the year 2013. Cancer immunotherapy. Science 2013;342(6165):1432-3
    • (2013) Science , vol.342 , Issue.6165 , pp. 1432-1433
    • Couzin-Frankel, J.1
  • 7
    • 84921397662 scopus 로고    scopus 로고
    • Manipulating immune regulatory pathways to enhance T cell stimulation
    • Pen JJ, Aerts JL, Liechtenstein T, et al. Manipulating immune regulatory pathways to enhance T cell stimulation. Immune response activation 2014; doi: 10.5772/57539
    • (2014) Immune Response Activation
    • Pen, J.J.1    Aerts, J.L.2    Liechtenstein, T.3
  • 8
    • 84897400607 scopus 로고    scopus 로고
    • Clinical immunotherapy of B-cell malignancy using CD19-Targeted CAR T-cells
    • Maher J. Clinical immunotherapy of B-cell malignancy using CD19-Targeted CAR T-cells. Curr Gene Ther 2014;14(1):35-43
    • (2014) Curr Gene Ther , vol.14 , Issue.1 , pp. 35-43
    • Maher, J.1
  • 9
    • 84906939134 scopus 로고    scopus 로고
    • Optimized dendritic cell-based immunotherapy for melanoma: The TriMix-formula
    • Van Lint S, Wilgenhof S, Heirman C, et al. Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula. Cancer Immunol Immunother 2014;63(9):959-67
    • (2014) Cancer Immunol Immunother , vol.63 , Issue.9 , pp. 959-967
    • Van Lint, S.1    Wilgenhof, S.2    Heirman, C.3
  • 10
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice
    • Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. J Exp Med 1973;137: 1142-62
    • (1973) J Exp Med , vol.137 , pp. 1142-1162
    • Steinman, R.M.1    Cohn, Z.A.2
  • 11
    • 36248965712 scopus 로고    scopus 로고
    • Dendritic cells: Understanding immunogenicity
    • Steinman RM. Dendritic cells: understanding immunogenicity. Eur J Immunol 2007;37(Suppl 1):S53-60
    • (2007) Eur J Immunol , vol.37 , pp. S53-S60
    • Steinman, R.M.1
  • 12
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature 2007; 449(7161):419-26
    • (2007) Nature , vol.449 , Issue.7161 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 13
    • 0021917676 scopus 로고
    • Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro
    • Schuler G, Steinman RM. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro. J Exp Med 1985;161(3):526-46
    • (1985) J Exp Med , vol.161 , Issue.3 , pp. 526-546
    • Schuler, G.1    Steinman, R.M.2
  • 14
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: The tolerogenic function of immature dendritic cells
    • Mahnke K, Schmitt E, Bonifaz L, et al. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 2002;80(5):477-83
    • (2002) Immunol Cell Biol , vol.80 , Issue.5 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3
  • 15
    • 84878002092 scopus 로고    scopus 로고
    • Trial watch: Dendritic cell-based interventions for cancer therapy
    • Galluzzi L, Senovilla L, Vacchelli E, et al. Trial watch: dendritic cell-based interventions for cancer therapy. Oncoimmunology 2012;1(7):1111-34
    • (2012) Oncoimmunology , vol.1 , Issue.7 , pp. 1111-1134
    • Galluzzi, L.1    Senovilla, L.2    Vacchelli, E.3
  • 16
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012;12(4):265-77
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 17
    • 84900842537 scopus 로고    scopus 로고
    • Dendritic cell maturation: Functional specialization through signaling specificity and transcriptional programming
    • Dalod M, Chelbi R, Malissen B, Lawrence T. Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming. EMBO J 2014;33(10):1104-16
    • (2014) EMBO J , vol.33 , Issue.10 , pp. 1104-1116
    • Dalod, M.1    Chelbi, R.2    Malissen, B.3    Lawrence, T.4
  • 18
    • 77953468036 scopus 로고    scopus 로고
    • Directing dendritic cell immunotherapy towards successful cancer treatment
    • Sabado RL, Bhardwaj N. Directing dendritic cell immunotherapy towards successful cancer treatment. Immunotherapy 2010;2(1):37-56
    • (2010) Immunotherapy , vol.2 , Issue.1 , pp. 37-56
    • Sabado, R.L.1    Bhardwaj, N.2
  • 19
    • 84859717471 scopus 로고    scopus 로고
    • Dendritic cells the tumor microenvironment and the challenges for an effective antitumor vaccination
    • Benencia F, Sprague L, McGinty J, et al. Dendritic cells the tumor microenvironment and the challenges for an effective antitumor vaccination. J Biomed Biotechnol 2012;2012:425-76
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 425-476
    • Benencia, F.1    Sprague, L.2    McGinty, J.3
  • 20
    • 17644370329 scopus 로고    scopus 로고
    • Cell biology of antigen processing in vitro and in vivo
    • Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annu Rev Immunol 2005;23:975-1028
    • (2005) Annu Rev Immunol , vol.23 , pp. 975-1028
    • Trombetta, E.S.1    Mellman, I.2
  • 21
  • 22
    • 84886900071 scopus 로고    scopus 로고
    • Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses
    • Nizzoli G, Krietsch J, Weick A, et al. Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses. Blood 2013;122(6):932-42
    • (2013) Blood , vol.122 , Issue.6 , pp. 932-942
    • Nizzoli, G.1    Krietsch, J.2    Weick, A.3
  • 23
    • 79958053079 scopus 로고    scopus 로고
    • Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status
    • Mittag D, Proietto AI, Loudovaris T, et al. Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol 2011;186(11):6207-17
    • (2011) J Immunol , vol.186 , Issue.11 , pp. 6207-6217
    • Mittag, D.1    Proietto, A.I.2    Loudovaris, T.3
  • 24
    • 0035838979 scopus 로고    scopus 로고
    • Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
    • Liu YJ. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 2001;106(3):259-62
    • (2001) Cell , vol.106 , Issue.3 , pp. 259-262
    • Liu, Y.J.1
  • 25
    • 0030026776 scopus 로고    scopus 로고
    • Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells
    • Hsu FJ, Benike C, Fagnoni F, et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med 1996;2(1):52-8
    • (1996) Nat Med , vol.2 , Issue.1 , pp. 52-58
    • Hsu, F.J.1    Benike, C.2    Fagnoni, F.3
  • 26
    • 34447624543 scopus 로고    scopus 로고
    • Current approaches in dendritic cell generation and future implications for cancer immunotherapy
    • Tuyaerts S, Aerts JL, Corthals J, et al. Current approaches in dendritic cell generation and future implications for cancer immunotherapy. Cancer Immunol Immunother 2007;56:1513-37
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1513-1537
    • Tuyaerts, S.1    Aerts, J.L.2    Corthals, J.3
  • 27
    • 34748886192 scopus 로고    scopus 로고
    • Dendritic-cell immunotherapy: From ex vivo loading to in vivo targeting
    • Tacken PJ, de Vries IJM, Torensma R, Figdor CG. Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol 2007;7(10):790-802
    • (2007) Nat Rev Immunol , vol.7 , Issue.10 , pp. 790-802
    • Tacken, P.J.1    De Vries, I.J.M.2    Torensma, R.3    Figdor, C.G.4
  • 28
    • 84884721824 scopus 로고    scopus 로고
    • A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients
    • Wilgenhof S, Van Nuffel AMT, Benteyn D, et al. A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients. Ann Oncol 2013; 24(10):2686-93
    • (2013) Ann Oncol , vol.24 , Issue.10 , pp. 2686-2693
    • Wilgenhof, S.1    Van Nuffel, A.M.T.2    Benteyn, D.3
  • 29
    • 79957904174 scopus 로고    scopus 로고
    • Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma
    • Wilgenhof S, Van Nuffel AM, Corthals J, et al. Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma. J Immunother 2011;34:448-56
    • (2011) J Immunother , vol.34 , pp. 448-456
    • Wilgenhof, S.1    Van Nuffel, A.M.2    Corthals, J.3
  • 30
    • 0041857805 scopus 로고    scopus 로고
    • Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA
    • Morse MA, Nair SK, Mosca PJ, et al. Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA. Cancer Invest 2003;21(3):341-9
    • (2003) Cancer Invest , vol.21 , Issue.3 , pp. 341-349
    • Morse, M.A.1    Nair, S.K.2    Mosca, P.J.3
  • 31
    • 4344560470 scopus 로고    scopus 로고
    • Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer
    • Caruso DA, Orme LM, Neale AM, et al. Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer. Neuro Oncol 2004;6(3): 236-46
    • (2004) Neuro Oncol , vol.6 , Issue.3 , pp. 236-246
    • Caruso, D.A.1    Orme, L.M.2    Neale, A.M.3
  • 32
    • 77958527547 scopus 로고    scopus 로고
    • Immunological response after therapeutic vaccination with WT1 mRNA-loaded dendritic cells in end-stage endometrial carcinoma
    • Coosemans A, Wölfl M, Berneman ZN, et al. Immunological response after therapeutic vaccination with WT1 mRNA-loaded dendritic cells in end-stage endometrial carcinoma. Anticancer Res 2010;30(9):3709-14
    • (2010) Anticancer Res , vol.30 , Issue.9 , pp. 3709-3714
    • Coosemans, A.1    Wölfl, M.2    Berneman, Z.N.3
  • 33
    • 84885015878 scopus 로고    scopus 로고
    • Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma
    • Coosemans A, Vanderstraeten A, Tuyaerts S, et al. Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma. Anticancer Res 2013;33(9): 3855-9
    • (2013) Anticancer Res , vol.33 , Issue.9 , pp. 3855-3859
    • Coosemans, A.1    Vanderstraeten, A.2    Tuyaerts, S.3
  • 34
    • 77956384935 scopus 로고    scopus 로고
    • Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-Targeted dendritic cell vaccination
    • Van Tendeloo VF, Van de Velde A, Van Driessche A, et al. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-Targeted dendritic cell vaccination. Proc Natl Acad Sci USA 2010;107:13824-9
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 13824-13829
    • Van Tendeloo, V.F.1    Van De Velde, A.2    Van Driessche, A.3
  • 35
    • 4143110212 scopus 로고    scopus 로고
    • Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-Transduced, CD34(+)-derived dendritic cell vaccination: A phase i trial in metastatic melanoma
    • Di Nicola M, Carlo-Stella C, Mortarini R, et al. Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-Transduced, CD34(+)-derived dendritic cell vaccination: a phase I trial in metastatic melanoma. Clin Cancer Res 2004;10(16):5381-90
    • (2004) Clin Cancer Res , vol.10 , Issue.16 , pp. 5381-5390
    • Di Nicola, M.1    Carlo-Stella, C.2    Mortarini, R.3
  • 36
    • 80054707651 scopus 로고    scopus 로고
    • Combination therapy of renal cell carcinoma or breast cancer patients with dendritic cell vaccine and IL-2: Results from a phase I/II trial
    • Baek S, Kim C-S, Kim S-B, et al. Combination therapy of renal cell carcinoma or breast cancer patients with dendritic cell vaccine and IL-2: results from a phase I/II trial. J Transl Med 2011;9:178
    • (2011) J Transl Med , vol.9 , pp. 178
    • Baek, S.1    Kim, C.-S.2    Kim, S.-B.3
  • 37
    • 8344227701 scopus 로고    scopus 로고
    • Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34 (+) blood progenitor cells
    • Mu LJ, Lazarova P, Gaudernack G, et al. Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34 (+) blood progenitor cells. Int J Immunopathol Pharmacol 2004;17(3): 255-63
    • (2004) Int J Immunopathol Pharmacol , vol.17 , Issue.3 , pp. 255-263
    • Mu, L.J.1    Lazarova, P.2    Gaudernack, G.3
  • 38
    • 33746034563 scopus 로고    scopus 로고
    • RNA loading of leukemic antigens into cord blood-derived dendritic cells for immunotherapy
    • Hsu AK, Kerr BM, Jones KL, et al. RNA loading of leukemic antigens into cord blood-derived dendritic cells for immunotherapy. Biol Blood Marrow Transplant 2006;12(8):855-67
    • (2006) Biol Blood Marrow Transplant , vol.12 , Issue.8 , pp. 855-867
    • Hsu, A.K.1    Kerr, B.M.2    Jones, K.L.3
  • 39
    • 0036167308 scopus 로고    scopus 로고
    • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors
    • Heiser A, Coleman D, Dannull J, et al. Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 2002;109(3):409-17
    • (2002) J Clin Invest , vol.109 , Issue.3 , pp. 409-417
    • Heiser, A.1    Coleman, D.2    Dannull, J.3
  • 40
    • 84871699575 scopus 로고    scopus 로고
    • Interleukin-15-induced CD56(+) myeloid dendritic cells combine potent tumor antigen presentation with direct tumoricidal potential
    • Anguille S, Lion E, Tel J, et al. Interleukin-15-induced CD56(+) myeloid dendritic cells combine potent tumor antigen presentation with direct tumoricidal potential. PLoS One 2012;7(12):e51851
    • (2012) PLoS One , vol.7 , Issue.12 , pp. e51851
    • Anguille, S.1    Lion, E.2    Tel, J.3
  • 41
    • 0035476477 scopus 로고    scopus 로고
    • Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells
    • Mohamadzadeh M, Berard F, Essert G, et al. Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J Exp Med 2001;194(7):1013-20
    • (2001) J Exp Med , vol.194 , Issue.7 , pp. 1013-1020
    • Mohamadzadeh, M.1    Berard, F.2    Essert, G.3
  • 42
    • 84884609956 scopus 로고    scopus 로고
    • Interleukin-15 dendritic cells as vaccine candidates for cancer immunotherapy
    • Anguille S, Lion E, Van den Bergh J, et al. Interleukin-15 dendritic cells as vaccine candidates for cancer immunotherapy. Hum Vaccin Immunother 2013;9(9):1956-61
    • (2013) Hum Vaccin Immunother , vol.9 , Issue.9 , pp. 1956-1961
    • Anguille, S.1    Lion, E.2    Van Den Bergh, J.3
  • 43
    • 27144481966 scopus 로고    scopus 로고
    • IL-4 is more effective than IL-13 for in vitro differentiation of dendritic cells from peripheral blood mononuclear cells
    • Ahn JS, Agrawal B. IL-4 is more effective than IL-13 for in vitro differentiation of dendritic cells from peripheral blood mononuclear cells. Int Immunol 2005; 17(10):1337-46
    • (2005) Int Immunol , vol.17 , Issue.10 , pp. 1337-1346
    • Ahn, J.S.1    Agrawal, B.2
  • 44
    • 33845415631 scopus 로고    scopus 로고
    • IL-13 replaces IL-4 in development of monocyte derived dendritic cells (MoDC) of swine
    • Bautista EM, Nfon C, Ferman GS, Golde WT. IL-13 replaces IL-4 in development of monocyte derived dendritic cells (MoDC) of swine. Vet Immunol Immunopathol 2007;115(1-2):56-67
    • (2007) Vet Immunol Immunopathol , vol.115 , Issue.1-2 , pp. 56-67
    • Bautista, E.M.1    Nfon, C.2    Ferman, G.S.3    Golde, W.T.4
  • 45
    • 0031937948 scopus 로고    scopus 로고
    • The influence of interleukin (IL)-4, IL-13, and Flt3 ligand on human dendritic cell differentiation from cord blood CD34+ progenitor cells
    • Rosenzwajg M, Camus S, Guigon M, Gluckman JC. The influence of interleukin (IL)-4, IL-13, and Flt3 ligand on human dendritic cell differentiation from cord blood CD34+ progenitor cells. Exp Hematol 1998;26(1):63-72
    • (1998) Exp Hematol , vol.26 , Issue.1 , pp. 63-72
    • Rosenzwajg, M.1    Camus, S.2    Guigon, M.3    Gluckman, J.C.4
  • 46
    • 0036464603 scopus 로고    scopus 로고
    • Interleukin-3 and interferon beta cooperate to induce differentiation of monocytes into dendritic cells with potent helper T-cell stimulatory properties
    • Buelens C, Bartholomé EJ, Amraoui Z, et al. Interleukin-3 and interferon beta cooperate to induce differentiation of monocytes into dendritic cells with potent helper T-cell stimulatory properties. Blood 2002;99(3):993-8
    • (2002) Blood , vol.99 , Issue.3 , pp. 993-998
    • Buelens, C.1    Bartholomé, E.J.2    Amraoui, Z.3
  • 47
    • 25644454416 scopus 로고    scopus 로고
    • Dendritic cells differentiated in the presence of IFN-beta and IL-3 are potent inducers of an antigen-specific CD8+ T cell response
    • Breckpot K, Corthals J, Bonehill A, et al. Dendritic cells differentiated in the presence of IFN-beta and IL-3 are potent inducers of an antigen-specific CD8+ T cell response. J Leukoc Biol 2005;78:898-908
    • (2005) J Leukoc Biol , vol.78 , pp. 898-908
    • Breckpot, K.1    Corthals, J.2    Bonehill, A.3
  • 48
    • 14744302052 scopus 로고    scopus 로고
    • Mature dendritic cells differentiated in the presence of interferon-beta and interleukin-3 prime functional antigen-specific CD8 T cells
    • Renneson J, Salio M, Mazouz N, et al. Mature dendritic cells differentiated in the presence of interferon-beta and interleukin-3 prime functional antigen-specific CD8 T cells. Clin Exp Immunol 2005;139(3):468-75
    • (2005) Clin Exp Immunol , vol.139 , Issue.3 , pp. 468-475
    • Renneson, J.1    Salio, M.2    Mazouz, N.3
  • 49
    • 30444445122 scopus 로고    scopus 로고
    • A new dendritic cell vaccine generated with interleukin-3 and interferon-beta induces CD8+ T cell responses against NA17-A2 tumor peptide in melanoma patients
    • Trakatelli M, Toungouz M, Blocklet D, et al. A new dendritic cell vaccine generated with interleukin-3 and interferon-beta induces CD8+ T cell responses against NA17-A2 tumor peptide in melanoma patients. Cancer Immunol Immunother 2006;55(4):469-74
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.4 , pp. 469-474
    • Trakatelli, M.1    Toungouz, M.2    Blocklet, D.3
  • 50
    • 70350404652 scopus 로고    scopus 로고
    • Fast generation of dendritic cells
    • Kvistborg P, Boegh M, Pedersen AW, et al. Fast generation of dendritic cells. Cell Immunol 2009;260(1):56-62
    • (2009) Cell Immunol , vol.260 , Issue.1 , pp. 56-62
    • Kvistborg, P.1    Boegh, M.2    Pedersen, A.W.3
  • 51
    • 84909580806 scopus 로고    scopus 로고
    • Fast monocyte-derived dendritic cell-based immunotherapy
    • Ramadan G. Fast monocyte-derived dendritic cell-based immunotherapy. Methods Mol Biol 2014;1139:131-44
    • (2014) Methods Mol Biol , vol.1139 , pp. 131-144
    • Ramadan, G.1
  • 52
    • 34547449658 scopus 로고    scopus 로고
    • A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines
    • Jarnjak-Jankovic S, Hammerstad H, Saebøe-Larssen S, et al. A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines. BMC Cancer 2007;7:119
    • (2007) BMC Cancer , vol.7 , pp. 119
    • Jarnjak-Jankovic, S.1    Hammerstad, H.2    Saebøe-Larssen, S.3
  • 53
    • 0037103350 scopus 로고    scopus 로고
    • Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells
    • Ponsaerts P, Van den Bosch G, Cools N, et al. Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells. J Immunol 2002;169(4):1669-75
    • (2002) J Immunol , vol.169 , Issue.4 , pp. 1669-1675
    • Ponsaerts, P.1    Van Den Bosch, G.2    Cools, N.3
  • 54
    • 34247097048 scopus 로고    scopus 로고
    • Hold on, the monocytes are coming!.
    • Villadangos JA. Hold on, the monocytes are coming!. Immunity 2007;26(4):390-2
    • (2007) Immunity , vol.26 , Issue.4 , pp. 390-392
    • Villadangos, J.A.1
  • 57
    • 4444329077 scopus 로고    scopus 로고
    • Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation
    • Schlecht G, Garcia S, Escriou N, et al. Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation. Blood 2004; 104(6):1808-15
    • (2004) Blood , vol.104 , Issue.6 , pp. 1808-1815
    • Schlecht, G.1    Garcia, S.2    Escriou, N.3
  • 58
    • 84873460701 scopus 로고    scopus 로고
    • Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients
    • Tel J, Aarntzen EH, Baba T, et al. Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients. Cancer Res 2013;73(3): 1063-75
    • (2013) Cancer Res , vol.73 , Issue.3 , pp. 1063-1075
    • Tel, J.1    Aarntzen, E.H.2    Baba, T.3
  • 59
    • 84896855922 scopus 로고    scopus 로고
    • Immunogenicity of targeted lentivectors
    • Goyvaerts C, Kurt DG, Van Lint S, et al. Immunogenicity of targeted lentivectors. Oncotarget 2014;5(3):704-15
    • (2014) Oncotarget , vol.5 , Issue.3 , pp. 704-715
    • Goyvaerts, C.1    Kurt, D.G.2    Van Lint, S.3
  • 60
    • 84904815108 scopus 로고    scopus 로고
    • Immunization of mice with lentiviral vectors targeted to MHC class II+ cells is due to preferential transduction of dendritic cells in vivo
    • Ciré S, Da Rocha S, Yao R, et al. Immunization of mice with lentiviral vectors targeted to MHC class II+ cells is due to preferential transduction of dendritic cells in vivo. PLoS ONE 2014;9(7):e101644
    • (2014) PLoS ONE , vol.9 , Issue.7 , pp. e101644
    • Ciré, S.1    Da Rocha, S.2    Yao, R.3
  • 61
    • 33846529159 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific antitumor immune responses
    • Lou Y, Liu C, Kim GJ, et al. Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific antitumor immune responses. J Immunol 2007;178(3):1534-41
    • (2007) J Immunol , vol.178 , Issue.3 , pp. 1534-1541
    • Lou, Y.1    Liu, C.2    Kim, G.J.3
  • 62
    • 69049089548 scopus 로고    scopus 로고
    • The prioritization of cancer antigens: A national cancer institute pilot project for the acceleration of translational research
    • Cheever MA, Allison JP, Ferris AS, et al. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clin Cancer Res 2009;15:5323-37
    • (2009) Clin Cancer Res , vol.15 , pp. 5323-5337
    • Cheever, M.A.1    Allison, J.P.2    Ferris, A.S.3
  • 63
    • 84991030590 scopus 로고    scopus 로고
    • Mining the mutanome: Developing highly personalized Immunotherapies based on mutational analysis of tumors
    • Overwijk WW, Wang E, Marincola FM, et al. Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors. J Immunother Cancer 2013;1:11
    • (2013) J Immunother Cancer , vol.1 , pp. 11
    • Overwijk, W.W.1    Wang, E.2    Marincola, F.M.3
  • 64
    • 84883251918 scopus 로고    scopus 로고
    • Targeting the tumor mutanome for personalized vaccination therapy
    • Kreiter S, Castle JC, Türeci O, Sahin U. Targeting the tumor mutanome for personalized vaccination therapy. Oncoimmunology 2012;1(5):768-9
    • (2012) Oncoimmunology , vol.1 , Issue.5 , pp. 768-769
    • Kreiter, S.1    Castle, J.C.2    Türeci, O.3    Sahin, U.4
  • 65
    • 84860521660 scopus 로고    scopus 로고
    • Dendritic Cells Loaded with mRNA Encoding Full-length Tumor Antigens Prime CD4(+) and CD8(+) T Cells in Melanoma Patients
    • Van Nuffel AM, Benteyn D, Wilgenhof S, et al. Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4(+) and CD8(+) T Cells in Melanoma Patients. Mol Ther 2012;20:1063-74
    • (2012) Mol Ther , vol.20 , pp. 1063-1074
    • Van Nuffel, A.M.1    Benteyn, D.2    Wilgenhof, S.3
  • 66
    • 13644263475 scopus 로고    scopus 로고
    • Exploiting dendritic cells for cancer immunotherapy: Genetic modification of dendritic cells
    • Breckpot K, Heirman C, Neyns B, Thielemans K. Exploiting dendritic cells for cancer immunotherapy: genetic modification of dendritic cells. J Gene Med 2004;6(11): 1175-88
    • (2004) J Gene Med , vol.6 , Issue.11 , pp. 1175-1188
    • Breckpot, K.1    Heirman, C.2    Neyns, B.3    Thielemans, K.4
  • 67
    • 74549174260 scopus 로고    scopus 로고
    • Dendritic cell-based cancer gene therapy
    • Smits EL, Anguille S, Cools N, et al. Dendritic cell-based cancer gene therapy. Hum Gene Ther 2009;20(10):1106-18
    • (2009) Hum Gene Ther , vol.20 , Issue.10 , pp. 1106-1118
    • Smits, E.L.1    Anguille, S.2    Cools, N.3
  • 68
    • 37349109250 scopus 로고    scopus 로고
    • Plasmid DNA-And messenger RNA-based anti-cancer vaccination
    • Weide B, Garbe C, Rammensee H-G, Pascolo S. Plasmid DNA- and messenger RNA-based anti-cancer vaccination. Immunol Lett 2008;115(1):33-42
    • (2008) Immunol Lett , vol.115 , Issue.1 , pp. 33-42
    • Weide, B.1    Garbe, C.2    Rammensee, H.-G.3    Pascolo, S.4
  • 69
    • 84878642106 scopus 로고    scopus 로고
    • Antitumor Vaccination with Synthetic mRNA: Strategies for in Vitro and in Vivo Preclinical Studies
    • Diken M, Kreiter S, Selmi A, et al. Antitumor Vaccination with Synthetic mRNA: strategies for In Vitro and In Vivo Preclinical Studies. Methods Mol Biol 2013;969:235-46
    • (2013) Methods Mol Biol , vol.969 , pp. 235-246
    • Diken, M.1    Kreiter, S.2    Selmi, A.3
  • 70
    • 84874724470 scopus 로고    scopus 로고
    • Mrna: From a chemical blueprint for protein production to an off-The-shelf therapeutic
    • Van Lint S, Heirman C, Thielemans K, Breckpot K. mRNA: from a chemical blueprint for protein production to an off-The-shelf therapeutic. Hum vaccin immunother 2013;9(2):265-74
    • (2013) Hum Vaccin Immunother , vol.9 , Issue.2 , pp. 265-274
    • Van Lint, S.1    Heirman, C.2    Thielemans, K.3    Breckpot, K.4
  • 71
    • 0029839058 scopus 로고    scopus 로고
    • Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo
    • Boczkowski D, Nair SK, Snyder D, Gilboa E. Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. J Exp Med 1996; 184(2):465-72
    • (1996) J Exp Med , vol.184 , Issue.2 , pp. 465-472
    • Boczkowski, D.1    Nair, S.K.2    Snyder, D.3    Gilboa, E.4
  • 72
    • 0031960397 scopus 로고    scopus 로고
    • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
    • Nair SK, Boczkowski D, Morse M, et al. Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nat Biotechnol 1998;16(4):364-9
    • (1998) Nat Biotechnol , vol.16 , Issue.4 , pp. 364-369
    • Nair, S.K.1    Boczkowski, D.2    Morse, M.3
  • 73
    • 79960145796 scopus 로고    scopus 로고
    • Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation
    • Diken M, Kreiter S, Selmi A, et al. Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation. Gene Ther 2011;18:702-8
    • (2011) Gene Ther , vol.18 , pp. 702-708
    • Diken, M.1    Kreiter, S.2    Selmi, A.3
  • 74
    • 39349103969 scopus 로고    scopus 로고
    • Vaccination with messenger RNA (mRNA).
    • Pascolo S. Vaccination with messenger RNA (mRNA). Handb Exp Pharmacol 2008;183(183):221-35
    • (2008) Handb Exp Pharmacol , vol.183 , Issue.183 , pp. 221-235
    • Pascolo, S.1
  • 75
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • Van Tendeloo VF, Ponsaerts P, Lardon F, et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 2001;98(1):49-56
    • (2001) Blood , vol.98 , Issue.1 , pp. 49-56
    • Van Tendeloo, V.F.1    Ponsaerts, P.2    Lardon, F.3
  • 76
    • 0036606341 scopus 로고    scopus 로고
    • Generation of large numbers of dendritic cells in a closed system using Cell Factories
    • Tuyaerts S, Noppe SM, Corthals J, et al. Generation of large numbers of dendritic cells in a closed system using Cell Factories. J Immunol Methods 2002;264(1-2):135-51
    • (2002) J Immunol Methods , vol.264 , Issue.1-2 , pp. 135-151
    • Tuyaerts, S.1    Noppe, S.M.2    Corthals, J.3
  • 77
    • 51649115332 scopus 로고    scopus 로고
    • High-level antigen expression and sustained antigen presentation in dendritic cells nucleofected with wild-Type viral mRNA but not DNA
    • Melhem NM, Gleason SM, Liu XD, Barratt-Boyes SM. High-level antigen expression and sustained antigen presentation in dendritic cells nucleofected with wild-Type viral mRNA but not DNA. Clin Vaccine Immunol 2008;15(9):1337-44
    • (2008) Clin Vaccine Immunol , vol.15 , Issue.9 , pp. 1337-1344
    • Melhem, N.M.1    Gleason, S.M.2    Liu, X.D.3    Barratt-Boyes, S.M.4
  • 78
    • 80053120336 scopus 로고    scopus 로고
    • MRNA-Lipoplex loaded microbubble contrast agents for ultrasound-Assisted transfection of dendritic cells
    • De Temmerman M-L, Dewitte H, Vandenbroucke RE, et al. mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-Assisted transfection of dendritic cells. Biomaterials 2011;32(34):9128-35
    • (2011) Biomaterials , vol.32 , Issue.34 , pp. 9128-9135
    • De Temmerman, M.-L.1    Dewitte, H.2    Vandenbroucke, R.E.3
  • 79
    • 33746651192 scopus 로고    scopus 로고
    • Characterization of the ribonuclease activity on the skin surface
    • Probst J, Brechtel S, Scheel B, et al. Characterization of the ribonuclease activity on the skin surface. Genet Vaccines Ther 2006;4:4
    • (2006) Genet Vaccines Ther , vol.4 , pp. 4
    • Probst, J.1    Brechtel, S.2    Scheel, B.3
  • 80
    • 84870185690 scopus 로고    scopus 로고
    • Lipoplexes carrying mRNA encoding Gag protein modulate dendritic cells to stimulate HIV-specific immune responses
    • De Haes W, Rejman J, Pollard C, et al. Lipoplexes carrying mRNA encoding Gag protein modulate dendritic cells to stimulate HIV-specific immune responses. Nanomedicine 2013;8(1):77-87
    • (2013) Nanomedicine , vol.8 , Issue.1 , pp. 77-87
    • De Haes, W.1    Rejman, J.2    Pollard, C.3
  • 81
    • 84907187676 scopus 로고    scopus 로고
    • The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-Triggered cancer immunotherapy
    • In press
    • Dewitte H, Van Lint S, Heirman C, et al. The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-Triggered cancer immunotherapy. J Contr Release 2014.In press
    • (2014) J Contr Release
    • Dewitte, H.1    Van Lint, S.2    Heirman, C.3
  • 82
    • 20844459312 scopus 로고    scopus 로고
    • Electroporation of immature and mature dendritic cells: Implications for dendritic cell-based vaccines
    • Michiels A, Tuyaerts S, Bonehill A, et al. Electroporation of immature and mature dendritic cells: implications for dendritic cell-based vaccines. Gene Ther 2005;12: 772-82
    • (2005) Gene Ther , vol.12 , pp. 772-782
    • Michiels, A.1    Tuyaerts, S.2    Bonehill, A.3
  • 83
    • 0036708241 scopus 로고    scopus 로고
    • Efficient genetic modification of murine dendritic cells by electroporation with mRNA
    • Van Meirvenne S, Straetman L, Heirman C , et al. Efficient genetic modification of murine dendritic cells by electroporation with mRNA. Cancer Gene Ther 2002;9(9): 787-97
    • (2002) Cancer Gene Ther , vol.9 , Issue.9 , pp. 787-797
    • Van Meirvenne, S.1    Straetman, L.2    Heirman, C.3
  • 84
    • 27444442561 scopus 로고    scopus 로고
    • A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma
    • Geiger C, Regn S, Weinzierl A, et al. A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma. J Transl Med 2005;3:29
    • (2005) J Transl Med , vol.3 , pp. 29
    • Geiger, C.1    Regn, S.2    Weinzierl, A.3
  • 85
    • 34848813477 scopus 로고    scopus 로고
    • High transfection efficiency gene expression and viability of monocyte-derived human dendritic cells after nonviral gene transfer
    • Landi A, Babiuk LA, van Drunen Littel-van den Hurk S. High transfection efficiency, gene expression, and viability of monocyte-derived human dendritic cells after nonviral gene transfer. J Leukoc Biol 2007;82(4):849-60
    • (2007) J Leukoc Biol , vol.82 , Issue.4 , pp. 849-860
    • Landi, A.1    Babiuk, L.A.2    Van Drunen Littel-Van Den Hurk, S.3
  • 86
    • 84908564034 scopus 로고    scopus 로고
    • Choose your models wisely: How different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro
    • Dewitte H, Verbeke R, Breckpot K, et al. Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro. J Control release 2014;doi: 10.1016/j. jconrel.2014.06.024
    • (2014) J Control Release
    • Dewitte, H.1    Verbeke, R.2    Breckpot, K.3
  • 87
    • 18744383825 scopus 로고    scopus 로고
    • In vivo depletion of CD4+CD25+regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells
    • Van Meirvenne S, Dullaers M, Heirman C, et al. In vivo depletion of CD4+CD25+regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells. Mol Ther 2005;12(5):922-32
    • (2005) Mol Ther , vol.12 , Issue.5 , pp. 922-932
    • Van Meirvenne, S.1    Dullaers, M.2    Heirman, C.3
  • 88
    • 33749168691 scopus 로고    scopus 로고
    • Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma
    • Markovic SN, Dietz AB, Greiner CW, et al. Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma. J Transl Med 2006;4:35
    • (2006) J Transl Med , vol.4 , pp. 35
    • Markovic, S.N.1    Dietz, A.B.2    Greiner, C.W.3
  • 89
    • 79956011495 scopus 로고    scopus 로고
    • A phase 1 single-dose study of fresolimumab an anti-TGF-b antibody in treatment-resistant primary focal segmental glomerulosclerosis
    • Trachtman H, Fervenza FC, Gipson DS, et al. A phase 1, single-dose study of fresolimumab, an anti-TGF-b antibody, in treatment-resistant primary focal segmental glomerulosclerosis. Kidney Int 2011;79(11): 1236-43
    • (2011) Kidney Int , vol.79 , Issue.11 , pp. 1236-1243
    • Trachtman, H.1    Fervenza, F.C.2    Gipson, D.S.3
  • 90
    • 84884561907 scopus 로고    scopus 로고
    • Molecular pathways: Coexpression of immune checkpoint molecules: Signaling pathways and implications for cancer immunotherapy
    • Nirschl CJ, Drake CG. Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy. Clin Cancer Res 2013;19(18):4917-24
    • (2013) Clin Cancer Res , vol.19 , Issue.18 , pp. 4917-4924
    • Nirschl, C.J.1    Drake, C.G.2
  • 91
    • 33746910738 scopus 로고    scopus 로고
    • Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
    • Kyte JA, Mu L, Aamdal S, et al. Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA. Cancer Gene Ther 2006;13:10:905-18
    • (2006) Cancer Gene Ther , vol.13 , Issue.10 , pp. 905-918
    • Kyte, J.A.1    Mu, L.2    Aamdal, S.3
  • 92
    • 30144444279 scopus 로고    scopus 로고
    • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
    • Dannull J, Su Z, Rizzieri D, et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 2005;115(12):3623-33
    • (2005) J Clin Invest , vol.115 , Issue.12 , pp. 3623-3633
    • Dannull, J.1    Su, Z.2    Rizzieri, D.3
  • 93
    • 84892996730 scopus 로고    scopus 로고
    • Design of an optimized Wilms' tumor 1 (WT1) mRNA construct for enhanced WT1 expression and improved immunogenicity in vitro and in vivo
    • Benteyn D, Anguille S, Van Lint S, et al. Design of an optimized Wilms' tumor 1 (WT1) mRNA construct for enhanced WT1 expression and improved immunogenicity in vitro and in vivo. Mol Ther Nucleic Acids 2013;2:e134
    • (2013) Mol Ther Nucleic Acids , vol.2 , pp. e134
    • Benteyn, D.1    Anguille, S.2    Van Lint, S.3
  • 94
    • 33845497677 scopus 로고    scopus 로고
    • Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
    • Holtkamp S, Kreiter S, Selmi A, et al. Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells. Blood 2006;108(13):4009-17
    • (2006) Blood , vol.108 , Issue.13 , pp. 4009-4017
    • Holtkamp, S.1    Kreiter, S.2    Selmi, A.3
  • 95
    • 85011942138 scopus 로고    scopus 로고
    • Determinants of intracellular RNA pharmacokinetics
    • Kuhn AN, Diken M, Kreiter S, et al. Determinants of intracellular RNA pharmacokinetics. RNA Biol 2011; 8(1):35-43
    • (2011) RNA Biol , vol.8 , Issue.1 , pp. 35-43
    • Kuhn, A.N.1    Diken, M.2    Kreiter, S.3
  • 96
    • 3442896311 scopus 로고    scopus 로고
    • Messenger RNA-based vaccines
    • Pascolo S. Messenger RNA-based vaccines. Expert Opin Biol Ther 2004;4(8):1285-94
    • (2004) Expert Opin Biol Ther , vol.4 , Issue.8 , pp. 1285-1294
    • Pascolo, S.1
  • 98
    • 0035819859 scopus 로고    scopus 로고
    • Regulation of mRNA stability in mammalian cells
    • Guhaniyogi J, Brewer G. Regulation of mRNA stability in mammalian cells. Gene 2001;265(1-2):11-23
    • (2001) Gene , vol.265 , Issue.1-2 , pp. 11-23
    • Guhaniyogi, J.1    Brewer, G.2
  • 99
    • 0033929810 scopus 로고    scopus 로고
    • Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system
    • Manuvakhova M, Keeling K, Bedwell DM. Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system. RNA 2000;6(7):1044-55
    • (2000) RNA , vol.6 , Issue.7 , pp. 1044-1055
    • Manuvakhova, M.1    Keeling, K.2    Bedwell, D.M.3
  • 100
    • 21044457258 scopus 로고    scopus 로고
    • Genetic approaches for the induction of a CD4+ T cell response in cancer immunotherapy
    • Bonehill A, Heirman C, Thielemans K. Genetic approaches for the induction of a CD4+ T cell response in cancer immunotherapy. J Gene Med 2005;7(6): 686-95
    • (2005) J Gene Med , vol.7 , Issue.6 , pp. 686-695
    • Bonehill, A.1    Heirman, C.2    Thielemans, K.3
  • 101
    • 2442689202 scopus 로고    scopus 로고
    • Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class i and class II molecules
    • Bonehill A, Heirman C, Tuyaerts S, et al. Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules. J Immunol 2004;172:6649-57
    • (2004) J Immunol , vol.172 , pp. 6649-6657
    • Bonehill, A.1    Heirman, C.2    Tuyaerts, S.3
  • 102
    • 0036735405 scopus 로고    scopus 로고
    • Enhanced induction of telomerase-specific CD4(+) T cells using dendritic cells transfected with RNA encoding a chimeric gene product
    • Su Z, Vieweg J, Weizer AZ, et al. Enhanced induction of telomerase-specific CD4(+) T cells using dendritic cells transfected with RNA encoding a chimeric gene product. Cancer Res 2002;62:5041-8
    • (2002) Cancer Res , vol.62 , pp. 5041-5048
    • Su, Z.1    Vieweg, J.2    Weizer, A.Z.3
  • 103
    • 40449083962 scopus 로고    scopus 로고
    • Increased antigen presentation efficiency by coupling antigens to MHC class i trafficking signals
    • Kreiter S, Selmi A, Diken M, et al. Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals. J Immunol 2008;180: 309-18
    • (2008) J Immunol , vol.180 , pp. 309-318
    • Kreiter, S.1    Selmi, A.2    Diken, M.3
  • 104
    • 77950948111 scopus 로고    scopus 로고
    • Lumenal part of the DC-LAMP protein is not required for induction of antigen-specific T cell responses by means of antigen-DC-LAMP messenger RNA-electroporated dendritic cells
    • De Keersmaecker B, Heirman C, Allard S, et al. Lumenal part of the DC-LAMP protein is not required for induction of antigen-specific T cell responses by means of antigen-DC-LAMP messenger RNA-electroporated dendritic cells. Hum Gene Ther 2010;21:479-85
    • (2010) Hum Gene Ther , vol.21 , pp. 479-485
    • De Keersmaecker, B.1    Heirman, C.2    Allard, S.3
  • 105
    • 84900301377 scopus 로고    scopus 로고
    • Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer
    • Tran E, Turcotte S, Gros A, et al. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer. Science 2014;344(6184):641-5
    • (2014) Science , vol.344 , Issue.6184 , pp. 641-645
    • Tran, E.1    Turcotte, S.2    Gros, A.3
  • 106
    • 75749136925 scopus 로고    scopus 로고
    • Dendritic cells for active anti-cancer immunotherapy: Targeting activation pathways through genetic modification
    • Breckpot K, Escors D. Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification. Endocr Metab Immune Disord Drug Targets 2009;9(4):328-43
    • (2009) Endocr Metab Immune Disord Drug Targets , vol.9 , Issue.4 , pp. 328-343
    • Breckpot, K.1    Escors, D.2
  • 107
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • Jonuleit H, Kühn U, Müller G, et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur J Immunol 1997;27(12):3135-42
    • (1997) Eur J Immunol , vol.27 , Issue.12 , pp. 3135-3142
    • Jonuleit, H.1    Kühn, U.2    Müller, G.3
  • 108
    • 10744224631 scopus 로고    scopus 로고
    • Maturation of Dendritic Cells Is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients
    • De Vries IJ, Lesterhuis WJ, Scharenborg NM, et al. Maturation of Dendritic Cells Is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients. Clin Cancer Res 2003;9:5091-100
    • (2003) Clin Cancer Res , vol.9 , pp. 5091-5100
    • De Vries, I.J.1    Lesterhuis, W.J.2    Scharenborg, N.M.3
  • 109
    • 20344372430 scopus 로고    scopus 로고
    • Clinical evaluation of dendritic cell vaccination for patients with recurrent glioma: Results of a clinical phase I/II trial
    • Yamanaka R, Homma J, Yajima N, et al. Clinical evaluation of dendritic cell vaccination for patients with recurrent glioma: results of a clinical phase I/II trial. Clin Cancer Res 2005;11(11):4160-7
    • (2005) Clin Cancer Res , vol.11 , Issue.11 , pp. 4160-4167
    • Yamanaka, R.1    Homma, J.2    Yajima, N.3
  • 110
    • 79955451697 scopus 로고    scopus 로고
    • Dendritic cell based tumor vaccination in prostate and renal cell cancer: A systematic review and meta-Analysis
    • Draube A, Klein-González N, Mattheus S, et al. Dendritic cell based tumor vaccination in prostate and renal cell cancer: a systematic review and meta-Analysis. PLoS One 2011;6(4):e18801
    • (2011) PLoS One , vol.6 , Issue.4 , pp. e18801
    • Draube, A.1    Klein-González, N.2    Mattheus, S.3
  • 111
    • 79951978155 scopus 로고    scopus 로고
    • Induction of CD8+ T-cell responses against novel glioma-Associated antigen peptides and clinical activity by vaccinations with {alpha}-Type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose i.n.
    • Okada H, Kalinski P, Ueda R, et al. Induction of CD8+ T-cell responses against novel glioma-Associated antigen peptides and clinical activity by vaccinations with {alpha}-Type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in. J Clin Oncol 2011;29(3):330-6
    • (2011) J Clin Oncol , vol.29 , Issue.3 , pp. 330-336
    • Okada, H.1    Kalinski, P.2    Ueda, R.3
  • 112
    • 84881222734 scopus 로고    scopus 로고
    • IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity
    • Carreno BM, Becker-Hapak M, Huang A, et al. IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity. J Clin Invest 2013;123(8):3383-94
    • (2013) J Clin Invest , vol.123 , Issue.8 , pp. 3383-3394
    • Carreno, B.M.1    Becker-Hapak, M.2    Huang, A.3
  • 113
    • 23944489407 scopus 로고    scopus 로고
    • Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani G, Rinaldi A, Bertoni F, et al. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 2005;6(8): 769-76
    • (2005) Nat Immunol , vol.6 , Issue.8 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3
  • 114
    • 33745945647 scopus 로고    scopus 로고
    • Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo
    • Warger T, Osterloh P, Rechtsteiner G, et al. Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo. Blood 2006;108(2):544-50
    • (2006) Blood , vol.108 , Issue.2 , pp. 544-550
    • Warger, T.1    Osterloh, P.2    Rechtsteiner, G.3
  • 115
    • 84855286306 scopus 로고    scopus 로고
    • Selective activation of intracellular signalling pathways in dendritic cells for cancer immunotherapy
    • Arce F, Kochan G, Breckpot K, et al. Selective activation of intracellular signalling pathways in dendritic cells for cancer immunotherapy. Anticancer Agents Med Chem 2012;12(1):29-39
    • (2012) Anticancer Agents Med Chem , vol.12 , Issue.1 , pp. 29-39
    • Arce, F.1    Kochan, G.2    Breckpot, K.3
  • 116
    • 34147107441 scopus 로고    scopus 로고
    • CD83 expression on dendritic cells and T cells: Correlation with effective immune responses
    • Aerts-Toegaert C, Heirman C, Tuyaerts S, et al. CD83 expression on dendritic cells and T cells: correlation with effective immune responses. Eur J Immunol 2007;37:686-95
    • (2007) Eur J Immunol , vol.37 , pp. 686-695
    • Aerts-Toegaert, C.1    Heirman, C.2    Tuyaerts, S.3
  • 117
    • 34347396781 scopus 로고    scopus 로고
    • Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells
    • Tuyaerts S, Van Meirvenne S, Bonehill A, et al. Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. J Leukoc Biol 2007;82(1):93-105
    • (2007) J Leukoc Biol , vol.82 , Issue.1 , pp. 93-105
    • Tuyaerts, S.1    Van Meirvenne, S.2    Bonehill, A.3
  • 118
    • 17044427679 scopus 로고    scopus 로고
    • Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand
    • Dannull J, Nair S, Su Z, et al. Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand. Blood 2005;105(8):3206-13
    • (2005) Blood , vol.105 , Issue.8 , pp. 3206-3213
    • Dannull, J.1    Nair, S.2    Su, Z.3
  • 119
    • 23944454886 scopus 로고    scopus 로고
    • Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes
    • Grünebach F, Kayser K, Weck MM, et al. Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes. Cancer Gene Ther 2005;12(9):749-56
    • (2005) Cancer Gene Ther , vol.12 , Issue.9 , pp. 749-756
    • Grünebach, F.1    Kayser, K.2    Weck, M.M.3
  • 120
    • 79957868214 scopus 로고    scopus 로고
    • The combination of 4-1BBL and CD40L strongly enhances the capacity of dendritic cells to stimulate HIV-specific T cell responses
    • De Keersmaecker B, Heirman C, Corthals J, et al. The combination of 4-1BBL and CD40L strongly enhances the capacity of dendritic cells to stimulate HIV-specific T cell responses. J Leukoc Biol 2011;89(6): 989-99
    • (2011) J Leukoc Biol , vol.89 , Issue.6 , pp. 989-999
    • De Keersmaecker, B.1    Heirman, C.2    Corthals, J.3
  • 121
    • 33846912739 scopus 로고    scopus 로고
    • Dendritic cells transfected with interleukin-12 and tumor-Associated antigen messenger RNA induce high avidity cytotoxic T cells
    • Bontkes HJ, Kramer D, Ruizendaal JJ, et al. Dendritic cells transfected with interleukin-12 and tumor-Associated antigen messenger RNA induce high avidity cytotoxic T cells. Gene Ther 2007;14(4): 366-75
    • (2007) Gene Ther , vol.14 , Issue.4 , pp. 366-375
    • Bontkes, H.J.1    Kramer, D.2    Ruizendaal, J.J.3
  • 122
    • 45249113920 scopus 로고    scopus 로고
    • Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells
    • Bontkes HJ, Kramer D, Ruizendaal JJ, et al. Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells. Clin Immunol 2008;127(3):375-84
    • (2008) Clin Immunol , vol.127 , Issue.3 , pp. 375-384
    • Bontkes, H.J.1    Kramer, D.2    Ruizendaal, J.J.3
  • 123
    • 38649110793 scopus 로고    scopus 로고
    • Introduction of functional chimeric E/Lselectin by RNA electroporation to target dendritic cells from blood to lymph nodes
    • Dörrie J, Schaft N, Müller I, et al. Introduction of functional chimeric E/Lselectin by RNA electroporation to target dendritic cells from blood to lymph nodes. Cancer Immunol Immunother 2008;57(4): 467-77
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.4 , pp. 467-477
    • Dörrie, J.1    Schaft, N.2    Müller, I.3
  • 124
    • 84908031412 scopus 로고    scopus 로고
    • Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells
    • Pen JJ, Keersmaecker BD, Heirman C, et al. Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells. Gene Ther 2014; 21(3):262-71
    • (2014) Gene Ther , vol.21 , Issue.3 , pp. 262-271
    • Pen, J.J.1    Keersmaecker, B.D.2    Heirman, C.3
  • 125
    • 82255181369 scopus 로고    scopus 로고
    • Enhancement of anti-Tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells
    • Pruitt SK, Boczkowski D, de Rosa N, et al. Enhancement of anti-Tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells. Eur J Immunol 2011;41(12):3553-63
    • (2011) Eur J Immunol , vol.41 , Issue.12 , pp. 3553-3563
    • Pruitt, S.K.1    Boczkowski, D.2    De Rosa, N.3
  • 126
    • 70449637946 scopus 로고    scopus 로고
    • Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy
    • Boczkowski D, Lee J, Pruitt S, Nair S. Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy. Cancer Gene Ther 2009;16(12):900-11
    • (2009) Cancer Gene Ther , vol.16 , Issue.12 , pp. 900-911
    • Boczkowski, D.1    Lee, J.2    Pruitt, S.3    Nair, S.4
  • 128
    • 16244381163 scopus 로고    scopus 로고
    • Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses
    • Abdel-Wahab Z, Cisco R, Dannull J, et al. Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses. J Surg Res 2005;124(2):264-73
    • (2005) J Surg Res , vol.124 , Issue.2 , pp. 264-273
    • Abdel-Wahab, Z.1    Cisco, R.2    Dannull, J.3
  • 129
    • 78650633859 scopus 로고    scopus 로고
    • Potency of mature CD40L RNA electroporated dendritic cells correlates with IL-12 secretion by tracking multifunctional CD8(+)/CD28(+) cytotoxic T-cell responses in vitro
    • DeBenedette MA, Calderhead DM, Tcherepanova IY, et al. Potency of mature CD40L RNA electroporated dendritic cells correlates with IL-12 secretion by tracking multifunctional CD8(+)/CD28(+) cytotoxic T-cell responses in vitro. J Immunother 2011;34(1):45-57
    • (2011) J Immunother , vol.34 , Issue.1 , pp. 45-57
    • Debenedette, M.A.1    Calderhead, D.M.2    Tcherepanova, I.Y.3
  • 130
    • 44349173032 scopus 로고    scopus 로고
    • Enhancing the T-cell stimulatory capacity of human dendritic cells by co-electroporation with CD40L, CD70 and constitutively active TLR4 encoding mRNA
    • Bonehill A, Tuyaerts S, Van Nuffel AMT, et al. Enhancing the T-cell stimulatory capacity of human dendritic cells by co-electroporation with CD40L, CD70 and constitutively active TLR4 encoding mRNA. Mol Ther 2008;16:1170-80
    • (2008) Mol Ther , vol.16 , pp. 1170-1180
    • Bonehill, A.1    Tuyaerts, S.2    Van Nuffel, A.M.T.3
  • 131
    • 84874640769 scopus 로고    scopus 로고
    • Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells (TriMixDC-MEL).
    • Benteyn D, Van Nuffel AMT, Wilgenhof S, et al. Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells (TriMixDC-MEL). Biomed Res Int 2013;2013:976383
    • (2013) Biomed Res Int , pp. 976383
    • Benteyn, D.1    Van Nuffel, A.M.T.2    Wilgenhof, S.3
  • 132
    • 84859417996 scopus 로고    scopus 로고
    • Preclinical evaluation of TriMix and antigen mRNA-based antitumor therapy
    • Van Lint S, Goyvaerts C, Maenhout S, et al. Preclinical evaluation of TriMix and antigen mRNA-based antitumor therapy. Cancer Res 2012;72(7):1661-71
    • (2012) Cancer Res , vol.72 , Issue.7 , pp. 1661-1671
    • Van Lint, S.1    Goyvaerts, C.2    Maenhout, S.3
  • 133
    • 84886945153 scopus 로고    scopus 로고
    • Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient
    • Van Nuffel AM, Benteyn D, Wilgenhof S, et al. Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient. Cancer Immunol Immunother 2011
    • (2011) Cancer Immunol Immunother.
    • Van Nuffel, A.M.1    Benteyn, D.2    Wilgenhof, S.3
  • 134
    • 66149186858 scopus 로고    scopus 로고
    • Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients
    • Bonehill A, Van Nuffel AMT, Corthals J, et al. Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients. Clin Cancer Res 2009;15(10): 3366-75
    • (2009) Clin Cancer Res , vol.15 , Issue.10 , pp. 3366-3375
    • Bonehill, A.1    Van Nuffel, A.M.T.2    Corthals, J.3
  • 135
    • 84881420246 scopus 로고    scopus 로고
    • Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70
    • Pen JJ, De Keersmaecker B, Maenhout SK, et al. Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70. J Immunol 2013;191(4):1976-83
    • (2013) J Immunol , vol.191 , Issue.4 , pp. 1976-1983
    • Pen, J.J.1    De Keersmaecker, B.2    Maenhout, S.K.3
  • 137
    • 84866458433 scopus 로고    scopus 로고
    • Dendritic cell-based vaccination in metastatic melanoma patients: Phase II clinical trial
    • Oshita C, Takikawa M, Kume A, et al. Dendritic cell-based vaccination in metastatic melanoma patients: phase II clinical trial. Oncol Rep 2012;28(4):1131-8
    • (2012) Oncol Rep , vol.28 , Issue.4 , pp. 1131-1138
    • Oshita, C.1    Takikawa, M.2    Kume, A.3
  • 138
    • 84866945151 scopus 로고    scopus 로고
    • Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients
    • Aarntzen EH, Schreibelt G, Bol K, et al. Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients. Clin Cancer Res 2012;18(19): 5460-70
    • (2012) Clin Cancer Res , vol.18 , Issue.19 , pp. 5460-5470
    • Aarntzen, E.H.1    Schreibelt, G.2    Bol, K.3
  • 139
    • 40449119721 scopus 로고    scopus 로고
    • Therapeutic immunization with human immunodeficiency virus type 1 (HIV-1) peptide-loaded dendritic cells is safe and induces immunogenicity in HIV-1-infected individuals
    • Connolly NC, Whiteside TL, Wilson C, et al. Therapeutic immunization with human immunodeficiency virus type 1 (HIV-1) peptide-loaded dendritic cells is safe and induces immunogenicity in HIV-1-infected individuals. Clin Vaccine Immunol 2008;15(2):284-92
    • (2008) Clin Vaccine Immunol , vol.15 , Issue.2 , pp. 284-292
    • Connolly, N.C.1    Whiteside, T.L.2    Wilson, C.3
  • 140
    • 33750326077 scopus 로고    scopus 로고
    • Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes
    • Grover A, Kim GJ, Lizée G, et al. Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes. Clin Cancer Res 2006; 12(19):5801-8
    • (2006) Clin Cancer Res , vol.12 , Issue.19 , pp. 5801-5808
    • Grover, A.1    Kim, G.J.2    Lizée, G.3
  • 141
    • 0034672104 scopus 로고    scopus 로고
    • Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer
    • Triozzi PL, Khurram R, Aldrich WA, et al. Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer. Cancer 2000;89(12):2646-54
    • (2000) Cancer , vol.89 , Issue.12 , pp. 2646-2654
    • Triozzi, P.L.1    Khurram, R.2    Aldrich, W.A.3
  • 142
    • 17844384207 scopus 로고    scopus 로고
    • Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens
    • Okada N, Tsujino M, Hagiwara Y, et al. Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens. Br J Cancer 2001;84(11): 1564-70
    • (2001) Br J Cancer , vol.84 , Issue.11 , pp. 1564-1570
    • Okada, N.1    Tsujino, M.2    Hagiwara, Y.3
  • 143
    • 0033565923 scopus 로고    scopus 로고
    • Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration
    • Eggert AA, Schreurs MW, Boerman OC, et al. Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration. Cancer Res 1999;59(14):3340-5
    • (1999) Cancer Res , vol.59 , Issue.14 , pp. 3340-3345
    • Eggert, A.A.1    Schreurs, M.W.2    Boerman, O.C.3
  • 144
    • 0141993954 scopus 로고    scopus 로고
    • Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control
    • Mullins DW, Sheasley SL, Ream RM, et al. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. J Exp Med 2003; 198(7):1023-34
    • (2003) J Exp Med , vol.198 , Issue.7 , pp. 1023-1034
    • Mullins, D.W.1    Sheasley, S.L.2    Ream, R.M.3
  • 145
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
    • Celluzzi CM, Mayordomo JI, Storkus WJ, et al. Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J Exp Med 1996;183(1): 283-7
    • (1996) J Exp Med , vol.183 , Issue.1 , pp. 283-287
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3
  • 146
    • 80052439234 scopus 로고    scopus 로고
    • Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients
    • Lesterhuis WJ, de Vries IJ, Schreibelt G, et al. Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clin Cancer Res 2011; 17(17):5725-35
    • (2011) Clin Cancer Res , vol.17 , Issue.17 , pp. 5725-5735
    • Lesterhuis, W.J.1    De Vries, I.J.2    Schreibelt, G.3
  • 147
    • 84862772889 scopus 로고    scopus 로고
    • Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient
    • Van Nuffel AM, Benteyn D, Wilgenhof S, et al. Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient. Cancer Immunol Immunother 2012;61(7):1033-43
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.7 , pp. 1033-1043
    • Van Nuffel, A.M.1    Benteyn, D.2    Wilgenhof, S.3
  • 148
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010;363(8):711-23
    • (2010) N Engl J Med , vol.363 , Issue.8 , pp. 711-723
    • Hodi, F.S.1    O'day, S.J.2    McDermott, D.F.3
  • 150
    • 84920287147 scopus 로고    scopus 로고
    • Phase II of autologous mRNA electroporated dendritic cells (TriMixDC-MEL) in combination with ipilimumab in patients with pretreated advanced melanoma. ASCO meeting (2014).
    • suppl):abstract 3014
    • Neyns B, Wilgenhof S, Corthals J, et al. Phase II of autologous mRNA electroporated dendritic cells (TriMixDC-MEL) in combination with ipilimumab in patients with pretreated advanced melanoma. ASCO meeting (2014). J Clin Oncol 2014; 32(suppl):abstract 3014
    • (2014) J Clin Oncol , vol.32
    • Neyns, B.1    Wilgenhof, S.2    Corthals, J.3
  • 151
    • 78549283854 scopus 로고    scopus 로고
    • Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity
    • Kreiter S, Selmi A, Diken M, et al. Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity. Cancer Res 2010;70(22): 9031-40
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 9031-9040
    • Kreiter, S.1    Selmi, A.2    Diken, M.3
  • 152
    • 67349142594 scopus 로고    scopus 로고
    • Polyinosinic polycytidylic acid prevents efficient antigen expression after mRNA electroporation of clinical grade dendritic cells
    • Schuurhuis DH, Lesterhuis WJ, Kramer M, et al. Polyinosinic polycytidylic acid prevents efficient antigen expression after mRNA electroporation of clinical grade dendritic cells. Cancer Immunol Immunother 2009;58(7):1109-15
    • (2009) Cancer Immunol Immunother , vol.58 , Issue.7 , pp. 1109-1115
    • Schuurhuis, D.H.1    Lesterhuis, W.J.2    Kramer, M.3
  • 153
    • 0035039114 scopus 로고    scopus 로고
    • Development of a dendritic cell (DC)-based vaccine for patients with advanced colorectal cancer
    • Rains N, Cannan RJ, Chen W, Stubbs RS. Development of a dendritic cell (DC)-based vaccine for patients with advanced colorectal cancer. Hepatogastroenterology 2001; 48(38):347-51
    • (2001) Hepatogastroenterology , vol.48 , Issue.38 , pp. 347-351
    • Rains, N.1    Cannan, R.J.2    Chen, W.3    Stubbs, R.S.4
  • 154
    • 0036203164 scopus 로고    scopus 로고
    • Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-Transfected dendritic cells
    • Nair SK, Morse M, Boczkowski D, et al. Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-Transfected dendritic cells. Ann Surg 2002;235(4):540-9
    • (2002) Ann Surg , vol.235 , Issue.4 , pp. 540-549
    • Nair, S.K.1    Morse, M.2    Boczkowski, D.3
  • 155
    • 0038066552 scopus 로고    scopus 로고
    • Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-Transfected dendritic cells
    • Su Z, Dannull J, Heiser A, et al. Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-Transfected dendritic cells. Cancer Res 2003;63(9):2127-33
    • (2003) Cancer Res , vol.63 , Issue.9 , pp. 2127-2133
    • Su, Z.1    Dannull, J.2    Heiser, A.3
  • 156
    • 14744280609 scopus 로고    scopus 로고
    • Results of a Phase i study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children with Stage 4 neuroblastoma
    • Caruso D, Orme LM, Amor GM, et al. Results of a Phase I study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children with Stage 4 neuroblastoma. Cancer 2005;103(6): 1280-91
    • (2005) Cancer , vol.103 , Issue.6 , pp. 1280-1291
    • Caruso, D.1    Orme, L.M.2    Amor, G.M.3
  • 157
    • 20144364773 scopus 로고    scopus 로고
    • Telomerase mRNA-Transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer
    • Su Z, Dannull J, Yang BK, et al. Telomerase mRNA-Transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer. J Immunol 2005; 174(6):3798-807
    • (2005) J Immunol , vol.174 , Issue.6 , pp. 3798-3807
    • Su, Z.1    Dannull, J.2    Yang, B.K.3
  • 158
    • 27144507469 scopus 로고    scopus 로고
    • Immunotherapy with allotumour mRNA-Transfected dendritic cells in androgen-resistant prostate cancer patients
    • Mu LJ, Kyte JA, Kvalheim G, et al. Immunotherapy with allotumour mRNA-Transfected dendritic cells in androgen-resistant prostate cancer patients. Br J Cancer 2005;93(7):749-56
    • (2005) Br J Cancer , vol.93 , Issue.7 , pp. 749-756
    • Mu, L.J.1    Kyte, J.A.2    Kvalheim, G.3
  • 159
    • 33847392474 scopus 로고    scopus 로고
    • T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
    • Kyte JA, Kvalheim G, Lislerud K, et al. T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells. Cancer Immunol Immunother 2007;56(5):659-75
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.5 , pp. 659-675
    • Kyte, J.A.1    Kvalheim, G.2    Lislerud, K.3
  • 160
    • 79959769072 scopus 로고    scopus 로고
    • HTERT mRNA dendritic cell vaccination: Complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
    • Suso EM, Dueland S, Rasmussen AM, et al. hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes. Cancer Immunol Immunother 2011;60:809-18
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 809-818
    • Suso, E.M.1    Dueland, S.2    Rasmussen, A.M.3
  • 161
    • 84883458285 scopus 로고    scopus 로고
    • Therapeutic vaccination against autologous cancer stem cells with mRNA-Transfected dendritic cells in patients with glioblastoma
    • Vik-Mo EO, Nyakas M, Mikkelsen BV, et al. Therapeutic vaccination against autologous cancer stem cells with mRNA-Transfected dendritic cells in patients with glioblastoma. Cancer Immunol Immunother 2013;62(9):1499-509
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.9 , pp. 1499-1509
    • Vik-Mo, E.O.1    Nyakas, M.2    Mikkelsen, B.V.3


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