In vivo depletion of CD4+CD25+ regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells

Molecular Therapy

Volumn 12, Issue 5, 2005, Pages 922-932

  Van Meirvenne, Sonja ^a   Dullaers, Melissa ^a   Heirman, Carlo ^a   Straetman, Lieven ^a   Michiels, Annelies ^a   Thielemans, Kris ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Cytotoxic T cell response; Dendritic cells; Immunotherapy; Maturation; OVA; Regulatory T cells

Indexed keywords

BASILIXIMAB; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE IMMUNOTHERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CANCER CELL CULTURE; CELL KINETICS; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC LYMPHOCYTE; DENDRITIC CELL; ELECTROPORATION; FEMALE; GENE EXPRESSION; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; LYMPHOCYTE FUNCTION; MELANOMA; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHENOTYPE; SURVIVAL; T LYMPHOCYTE; TRANSGENE; TUMOR GROWTH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGEN PRESENTATION; ANTIGENS, CD24; ANTIGENS, NEOPLASM; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; ELECTROPORATION; FEMALE; GENE TRANSFER TECHNIQUES; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; NEOPLASMS; RECEPTORS, INTERLEUKIN-2; RNA, MESSENGER; T-LYMPHOCYTES; TRANSDUCTION, GENETIC; VACCINES, DNA;

ANIMALIA; MURINAE;

EID: 18744383825     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.02.029     Document Type: Article

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