Monensin-mediated growth inhibition in acute myelogenous leukemia cells via cell cycle arrest and apoptosis

International Journal of Cancer

Volumn 101, Issue 3, 2002, Pages 235-242

  Park, Woo H ^a,c   Lee, Myung S ^b   Park, Keunchil ^a   Kim, Eun S ^a   Kim, Byoung K ^a   Lee, Young Y ^a,c  

^a Seoul National University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

Acute myelogenous leukemia; Apoptosis; CDK; Cell cycle; Monensin

Indexed keywords

ANTIBODY; CASPASE 3; CASPASE 8; CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 6; MONENSIN; PROTEIN BAX; PROTEIN P53;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL LINE; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; FEMALE; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; LEUKEMIA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR VOLUME;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; IONOPHORES; LEUKEMIA, MYELOCYTIC, ACUTE; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MONENSIN; POLY(ADP-RIBOSE) POLYMERASES; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0037144364     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10592     Document Type: Article

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