-
1
-
-
0037365789
-
ATM and related protein kinases: safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 2003, 3:155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
2
-
-
15844394846
-
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
-
Falck J., Coates J., Jackson S.P. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 2005, 434:605-611.
-
(2005)
Nature
, vol.434
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
3
-
-
0042854721
-
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain
-
Craig A., Scott M., Burch L., Smith G., Ball K., Hupp T. Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain. EMBO Rep. 2003, 4:787-792.
-
(2003)
EMBO Rep.
, vol.4
, pp. 787-792
-
-
Craig, A.1
Scott, M.2
Burch, L.3
Smith, G.4
Ball, K.5
Hupp, T.6
-
4
-
-
0043066731
-
Regulating mammalian checkpoints through Cdc25 inactivation
-
Donzelli M., Draetta G.F. Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Rep. 2003, 4:671-677.
-
(2003)
EMBO Rep.
, vol.4
, pp. 671-677
-
-
Donzelli, M.1
Draetta, G.F.2
-
5
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
Falck J., Mailand N., Syljuasen R.G., Bartek J., Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 2001, 410:842-847.
-
(2001)
Nature
, vol.410
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Lukas, J.5
-
6
-
-
0029802591
-
P53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
Chen X., Ko L.J., Jayaraman L., Prives C. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 1996, 10:2438-2451.
-
(1996)
Genes Dev.
, vol.10
, pp. 2438-2451
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
Prives, C.4
-
7
-
-
84874948475
-
A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis
-
Kracikova M., Akiri G., George A., Sachidanandam R., Aaronson S.A. A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis. Cell Death Differ. 2013, 20:576-578.
-
(2013)
Cell Death Differ.
, vol.20
, pp. 576-578
-
-
Kracikova, M.1
Akiri, G.2
George, A.3
Sachidanandam, R.4
Aaronson, S.A.5
-
8
-
-
0033612287
-
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
-
Martin S.G., Laroche T., Suka N., Grunstein M., Gasser S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 1999, 97:621-633.
-
(1999)
Cell
, vol.97
, pp. 621-633
-
-
Martin, S.G.1
Laroche, T.2
Suka, N.3
Grunstein, M.4
Gasser, S.M.5
-
9
-
-
0033539095
-
DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p
-
McAinsh A.D., Scott-Drew S., Murray J.A., Jackson S.P. DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p. Curr. Biol. 1999, 9:963-966.
-
(1999)
Curr. Biol.
, vol.9
, pp. 963-966
-
-
McAinsh, A.D.1
Scott-Drew, S.2
Murray, J.A.3
Jackson, S.P.4
-
10
-
-
0033612189
-
MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
-
Mills K.D., Sinclair D.A., Guarente L. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell 1999, 97:609-620.
-
(1999)
Cell
, vol.97
, pp. 609-620
-
-
Mills, K.D.1
Sinclair, D.A.2
Guarente, L.3
-
11
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein M., McVey M., Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 1999, 13:2570-2580.
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
12
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
Kawahara T.L., Michishita E., Adler A.S., Damian M., Berber E., Lin M., McCord R.A., Ongaigui K.C., Boxer L.D., Chang H.Y., Chua K.F. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell 2009, 136:62-74.
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
Damian, M.4
Berber, E.5
Lin, M.6
McCord, R.A.7
Ongaigui, K.C.8
Boxer, L.D.9
Chang, H.Y.10
Chua, K.F.11
-
13
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P., Michan S., McVay M., Mostoslavsky R., Vann J., Park S.K., Hartlerode A., Stegmuller J., Hafner A., Loerch P., Wright S.M., Mills K.D., Bonni A., Yankner B.A., Scully R., Prolla T.A., Alt F.W., Sinclair D.A. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 2008, 135:907-918.
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
Wright, S.M.11
Mills, K.D.12
Bonni, A.13
Yankner, B.A.14
Scully, R.15
Prolla, T.A.16
Alt, F.W.17
Sinclair, D.A.18
-
14
-
-
78651468722
-
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
Someya S., Yu W., Hallows W.C., Xu J., Vann J.M., Leeuwenburgh C., Tanokura M., Denu J.M., Prolla T.A. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 2010, 143:802-812.
-
(2010)
Cell
, vol.143
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
Xu, J.4
Vann, J.M.5
Leeuwenburgh, C.6
Tanokura, M.7
Denu, J.M.8
Prolla, T.A.9
-
15
-
-
77950351604
-
SIRT1 deacetylates APE1 and regulates cellular base excision repair
-
Yamamori T., DeRicco J., Naqvi A., Hoffman T.A., Mattagajasingh I., Kasuno K., Jung S.B., Kim C.S., Irani K. SIRT1 deacetylates APE1 and regulates cellular base excision repair. Nucleic Acids Res. 2010, 38:832-845.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 832-845
-
-
Yamamori, T.1
DeRicco, J.2
Naqvi, A.3
Hoffman, T.A.4
Mattagajasingh, I.5
Kasuno, K.6
Jung, S.B.7
Kim, C.S.8
Irani, K.9
-
16
-
-
84863453769
-
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
-
Barber M.F., Michishita-Kioi E., Xi Y., Tasselli L., Kioi M., Moqtaderi Z., Tennen R.I., Paredes S., Young N.L., Chen K., Struhl K., Garcia B.A., Gozani O., Li W., Chua K.F. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature 2012, 487:114-118.
-
(2012)
Nature
, vol.487
, pp. 114-118
-
-
Barber, M.F.1
Michishita-Kioi, E.2
Xi, Y.3
Tasselli, L.4
Kioi, M.5
Moqtaderi, Z.6
Tennen, R.I.7
Paredes, S.8
Young, N.L.9
Chen, K.10
Struhl, K.11
Garcia, B.A.12
Gozani, O.13
Li, W.14
Chua, K.F.15
-
17
-
-
33744466971
-
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
-
Ford E., Voit R., Liszt G., Magin C., Grummt I., Guarente L. Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev. 2006, 20:1075-1080.
-
(2006)
Genes Dev.
, vol.20
, pp. 1075-1080
-
-
Ford, E.1
Voit, R.2
Liszt, G.3
Magin, C.4
Grummt, I.5
Guarente, L.6
-
18
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
Michishita E., Park J.Y., Burneskis J.M., Barrett J.C., Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Biol. Cell 2005, 16:4623-4635.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
19
-
-
79959363092
-
SIRT6 promotes DNA repair under stress by activating PARP1
-
Mao Z., Hine C., Tian X., Van Meter M., Au M., Vaidya A., Seluanov A., Gorbunova V. SIRT6 promotes DNA repair under stress by activating PARP1. Science 2011, 332:1443-1446.
-
(2011)
Science
, vol.332
, pp. 1443-1446
-
-
Mao, Z.1
Hine, C.2
Tian, X.3
Van Meter, M.4
Au, M.5
Vaidya, A.6
Seluanov, A.7
Gorbunova, V.8
-
20
-
-
64049090625
-
Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging
-
Vakhrusheva O., Braeuer D., Liu Z., Braun T., Bober E. Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging. J. Physiol. Pharmacol. 2008, 9:201-212.
-
(2008)
J. Physiol. Pharmacol.
, vol.9
, pp. 201-212
-
-
Vakhrusheva, O.1
Braeuer, D.2
Liu, Z.3
Braun, T.4
Bober, E.5
-
21
-
-
64849107827
-
Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis
-
Grob A., Roussel P., Wright J.E., McStay B., Hernandez-Verdun D., Sirri V. Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis. J. Cell Sci. 2009, 122:489-498.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 489-498
-
-
Grob, A.1
Roussel, P.2
Wright, J.E.3
McStay, B.4
Hernandez-Verdun, D.5
Sirri, V.6
-
22
-
-
41449083867
-
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
-
Vakhrusheva O., Smolka C., Gajawada P., Kostin S., Boettger T., Kubin T., Braun T., Bober E. Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice. Circ. Res. 2008, 102:703-710.
-
(2008)
Circ. Res.
, vol.102
, pp. 703-710
-
-
Vakhrusheva, O.1
Smolka, C.2
Gajawada, P.3
Kostin, S.4
Boettger, T.5
Kubin, T.6
Braun, T.7
Bober, E.8
-
23
-
-
84887613799
-
SIRT7 represses myc activity to suppress ER stress and prevent fatty liver disease
-
Shin J., He M., Liu Y., Paredes S., Villanova L., Brown K., Qiu X., Nabavi N., Mohrin M., Wojnoonski K., Li P., Cheng H.L., Murphy A.J., Valenzuela D.M., Luo H., Kapahi P., Krauss R., Mostoslavsky R., Yancopoulos G.D., Alt F.W., Chua K.F., Chen D. SIRT7 represses myc activity to suppress ER stress and prevent fatty liver disease. Cell Rep. 2013, 5:654-665.
-
(2013)
Cell Rep.
, vol.5
, pp. 654-665
-
-
Shin, J.1
He, M.2
Liu, Y.3
Paredes, S.4
Villanova, L.5
Brown, K.6
Qiu, X.7
Nabavi, N.8
Mohrin, M.9
Wojnoonski, K.10
Li, P.11
Cheng, H.L.12
Murphy, A.J.13
Valenzuela, D.M.14
Luo, H.15
Kapahi, P.16
Krauss, R.17
Mostoslavsky, R.18
Yancopoulos, G.D.19
Alt, F.W.20
Chua, K.F.21
Chen, D.22
more..
-
24
-
-
84856755475
-
Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription
-
(M111 015156)
-
Tsai Y.C., Greco T.M., Boonmee A., Miteva Y., Cristea I.M. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Mol. Cell. Proteomics 2012, 11. (M111 015156).
-
(2012)
Mol. Cell. Proteomics
, vol.11
-
-
Tsai, Y.C.1
Greco, T.M.2
Boonmee, A.3
Miteva, Y.4
Cristea, I.M.5
-
25
-
-
84887172167
-
Repression of RNA polymerase I upon stress ss caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7
-
Chen S., Seiler J., Santiago-Reichelt M., Felbel K., Grummt I., Voit R. Repression of RNA polymerase I upon stress ss caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7. Mol. Cell 2013, 52:303-313.
-
(2013)
Mol. Cell
, vol.52
, pp. 303-313
-
-
Chen, S.1
Seiler, J.2
Santiago-Reichelt, M.3
Felbel, K.4
Grummt, I.5
Voit, R.6
-
26
-
-
84880558721
-
Inhibits the activity of hypoxia-inducible factors
-
Hubbi M.E., Hu H., Kshitiz D.M., Gilkes G.L., Semenza Sirtuin-7 Inhibits the activity of hypoxia-inducible factors. J. Biol. Chem. 2013, 288:20768-20775.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 20768-20775
-
-
Hubbi, M.E.1
Hu, H.2
Kshitiz, D.M.3
Gilkes, G.L.4
Semenza, S.-7.5
-
27
-
-
84921032296
-
SIRT7 plays a role in ribosome biogenesis and protein synthesis
-
Tsai Y.C., Greco T.M., Cristea I.M. SIRT7 plays a role in ribosome biogenesis and protein synthesis. Mol. Cell. Proteomics 2013, 10:10.
-
(2013)
Mol. Cell. Proteomics
, vol.10
, pp. 10
-
-
Tsai, Y.C.1
Greco, T.M.2
Cristea, I.M.3
-
28
-
-
84922672604
-
Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistance
-
(1596)
-
Aljada A., Saleh A.M., Al Suwaidan S. Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistance. Diagn. Pathol. 2014, 9:1746. (1596).
-
(2014)
Diagn. Pathol.
, vol.9
, pp. 1746
-
-
Aljada, A.1
Saleh, A.M.2
Al Suwaidan, S.3
-
29
-
-
84897484512
-
SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway
-
Yoshizawa T., Karim M.F., Sato Y., Senokuchi T., Miyata K., Fukuda T., Go C., Tasaki M., Uchimura K., Kadomatsu T., Tian Z., Smolka C., Sawa T., Takeya M., Tomizawa K., Ando Y., Araki E., Akaike T., Braun T., Oike Y., Bober E., Yamagata K. SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway. Cell Metab. 2014, 19:712-721.
-
(2014)
Cell Metab.
, vol.19
, pp. 712-721
-
-
Yoshizawa, T.1
Karim, M.F.2
Sato, Y.3
Senokuchi, T.4
Miyata, K.5
Fukuda, T.6
Go, C.7
Tasaki, M.8
Uchimura, K.9
Kadomatsu, T.10
Tian, Z.11
Smolka, C.12
Sawa, T.13
Takeya, M.14
Tomizawa, K.15
Ando, Y.16
Araki, E.17
Akaike, T.18
Braun, T.19
Oike, Y.20
Bober, E.21
Yamagata, K.22
more..
-
30
-
-
84879943944
-
Intracellular distribution of human SIRT7 and mapping of the nuclear/nucleolar localization signal
-
Kiran S., Chatterjee N., Singh S., Kaul S.C., Wadhwa R., Ramakrishna G. Intracellular distribution of human SIRT7 and mapping of the nuclear/nucleolar localization signal. FEBS J. 2013, 280:3451-3466.
-
(2013)
FEBS J.
, vol.280
, pp. 3451-3466
-
-
Kiran, S.1
Chatterjee, N.2
Singh, S.3
Kaul, S.C.4
Wadhwa, R.5
Ramakrishna, G.6
-
31
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereira-Smith O., et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 1995, 92:9363-9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
32
-
-
0035545996
-
Mammalian G1- and S-phase checkpoints in response to DNA damage
-
Bartek J., Lukas J. Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr. Opin. Cell Biol. 2001, 13:738-747.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 738-747
-
-
Bartek, J.1
Lukas, J.2
-
33
-
-
84862528549
-
Induction of a G1-S checkpoint in fission yeast
-
Boe C.A., Krohn M., Rodland G.E., Capiaghi C., Maillard O., Thoma F., Boye E., Grallert B. Induction of a G1-S checkpoint in fission yeast. Proc. Natl. Acad. Sci. USA 2012, 109:9911-9916.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 9911-9916
-
-
Boe, C.A.1
Krohn, M.2
Rodland, G.E.3
Capiaghi, C.4
Maillard, O.5
Thoma, F.6
Boye, E.7
Grallert, B.8
-
34
-
-
0021151237
-
Damage mediated by mammalian DNA topoisomerase II
-
Tewey K.M., Rowe T.C., Yang L., Halligan B.D., Liu L.F., Adriamycin-induced D.N.A. damage mediated by mammalian DNA topoisomerase II. Science 1984, 226:466-468.
-
(1984)
Science
, vol.226
, pp. 466-468
-
-
Tewey, K.M.1
Rowe, T.C.2
Yang, L.3
Halligan, B.D.4
Liu, L.F.5
Adriamycin-induced, D.N.A.6
-
35
-
-
0033606852
-
Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs
-
Chang B.D., Xuan Y., Broude E.V., Zhu H., Schott B., Fang J., Roninson I.B. Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene 1999, 18:4808-4818.
-
(1999)
Oncogene
, vol.18
, pp. 4808-4818
-
-
Chang, B.D.1
Xuan, Y.2
Broude, E.V.3
Zhu, H.4
Schott, B.5
Fang, J.6
Roninson, I.B.7
-
36
-
-
23044467656
-
Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype
-
Eom Y.W., Kim M.A., Park S.S., Goo M.J., Kwon H.J., Sohn S., Kim W.H., Yoon G., Choi K.S. Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene 2005, 24:4765-4777.
-
(2005)
Oncogene
, vol.24
, pp. 4765-4777
-
-
Eom, Y.W.1
Kim, M.A.2
Park, S.S.3
Goo, M.J.4
Kwon, H.J.5
Sohn, S.6
Kim, W.H.7
Yoon, G.8
Choi, K.S.9
-
37
-
-
33748464742
-
Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis
-
Lee E.R., Kim J.Y., Kang Y.J., Ahn J.Y., Kim J.H., Kim B.W., Choi H.Y., Jeong M.Y., Cho S.G. Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis. Biochim. Biophys. Acta 2006, 9:958-968.
-
(2006)
Biochim. Biophys. Acta
, vol.9
, pp. 958-968
-
-
Lee, E.R.1
Kim, J.Y.2
Kang, Y.J.3
Ahn, J.Y.4
Kim, J.H.5
Kim, B.W.6
Choi, H.Y.7
Jeong, M.Y.8
Cho, S.G.9
-
38
-
-
0042697468
-
The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide
-
Brantley-Finley C., Lyle C.S., Du L., Goodwin M.E., Hall T., Szwedo D., Kaushal G.P., Chambers T.C. The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. Biochem. Pharmacol. 2003, 66:459-469.
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 459-469
-
-
Brantley-Finley, C.1
Lyle, C.S.2
Du, L.3
Goodwin, M.E.4
Hall, T.5
Szwedo, D.6
Kaushal, G.P.7
Chambers, T.C.8
-
39
-
-
0031896910
-
Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction
-
Hazzalin C.A., Le Panse R., Cano E., Mahadevan L.C. Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction. Mol. Cell. Biol. 1998, 18:1844-1854.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1844-1854
-
-
Hazzalin, C.A.1
Le Panse, R.2
Cano, E.3
Mahadevan, L.C.4
-
40
-
-
0032530486
-
DNA damage activates p53 through a phosphorylation-acetylation cascade
-
Sakaguchi K., Herrera J.E., Saito S., Miki T., Bustin M., Vassilev A., Anderson C.W., Appella E. DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev. 1998, 12:2831-2841.
-
(1998)
Genes Dev.
, vol.12
, pp. 2831-2841
-
-
Sakaguchi, K.1
Herrera, J.E.2
Saito, S.3
Miki, T.4
Bustin, M.5
Vassilev, A.6
Anderson, C.W.7
Appella, E.8
-
41
-
-
38449083922
-
In-vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Shinohara T., Uesugi M. In-vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Tanpakushitsu Kakusan Koso 2007, 52:1816-1817.
-
(2007)
Tanpakushitsu Kakusan Koso
, vol.52
, pp. 1816-1817
-
-
Shinohara, T.1
Uesugi, M.2
-
42
-
-
84888003905
-
Hsa-miR-125b suppresses bladder cancer development by down-regulating oncogene SIRT7 and oncogenic long non-coding RNA MALAT1
-
Han Y., Liu Y., Zhang H., Wang T., Diao R., Jiang Z., Gui Y., Cai Z. Hsa-miR-125b suppresses bladder cancer development by down-regulating oncogene SIRT7 and oncogenic long non-coding RNA MALAT1. FEBS Lett. 2013, 587:3875-3882.
-
(2013)
FEBS Lett.
, vol.587
, pp. 3875-3882
-
-
Han, Y.1
Liu, Y.2
Zhang, H.3
Wang, T.4
Diao, R.5
Jiang, Z.6
Gui, Y.7
Cai, Z.8
-
43
-
-
84874487252
-
Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b
-
Kim J.K., Noh J.H., Jung K.H., Eun J.W., Bae H.J., Kim M.G., Chang Y.G., Shen Q., Park W.S., Lee J.Y., Borlak J., Nam S.W. Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b. Hepatology 2013, 57:1055-1067.
-
(2013)
Hepatology
, vol.57
, pp. 1055-1067
-
-
Kim, J.K.1
Noh, J.H.2
Jung, K.H.3
Eun, J.W.4
Bae, H.J.5
Kim, M.G.6
Chang, Y.G.7
Shen, Q.8
Park, W.S.9
Lee, J.Y.10
Borlak, J.11
Nam, S.W.12
-
44
-
-
0024425887
-
Checkpoints: controls that ensure the order of cell cycle events
-
Hartwell L.H., Weinert T.A. Checkpoints: controls that ensure the order of cell cycle events. Science 1989, 246:629-634.
-
(1989)
Science
, vol.246
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.A.2
-
45
-
-
33947313992
-
A novel checkpoint mechanism regulating the G1/S transition
-
Tvegard T., Soltani H., Skjolberg H.C., Krohn M., Nilssen E.A., Kearsey S.E., Grallert B., Boye E. A novel checkpoint mechanism regulating the G1/S transition. Genes Dev. 2007, 21:649-654.
-
(2007)
Genes Dev.
, vol.21
, pp. 649-654
-
-
Tvegard, T.1
Soltani, H.2
Skjolberg, H.C.3
Krohn, M.4
Nilssen, E.A.5
Kearsey, S.E.6
Grallert, B.7
Boye, E.8
-
46
-
-
0033019306
-
Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression
-
Fritz G., Kaina B. Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression. Mol. Cell. Biol. 1999, 19:1768-1774.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1768-1774
-
-
Fritz, G.1
Kaina, B.2
-
47
-
-
84879076495
-
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
-
Chen X., Chen J., Gan S., Guan H., Zhou Y., Ouyang Q., Shi J. DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control. BMC Biol. 2013, 11:1741-7007.
-
(2013)
BMC Biol.
, vol.11
, pp. 1741-7007
-
-
Chen, X.1
Chen, J.2
Gan, S.3
Guan, H.4
Zhou, Y.5
Ouyang, Q.6
Shi, J.7
-
48
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005, 120:513-522.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
49
-
-
0242552555
-
Influence of induced reactive oxygen species in p53-mediated cell fate decisions
-
Macip S., Igarashi M., Berggren P., Yu J., Lee S.W., Aaronson S.A. Influence of induced reactive oxygen species in p53-mediated cell fate decisions. Mol. Cell. Biol. 2003, 23:8576-8585.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8576-8585
-
-
Macip, S.1
Igarashi, M.2
Berggren, P.3
Yu, J.4
Lee, S.W.5
Aaronson, S.A.6
-
50
-
-
78650306296
-
Estrogen levels act as a rheostat on p53 levels and modulate p53-dependent responses in breast cancer cell lines
-
Fernandez-Cuesta L., Anaganti S., Hainaut P., Olivier M. Estrogen levels act as a rheostat on p53 levels and modulate p53-dependent responses in breast cancer cell lines. Breast Cancer Res. Treat. 2011, 125:35-42.
-
(2011)
Breast Cancer Res. Treat.
, vol.125
, pp. 35-42
-
-
Fernandez-Cuesta, L.1
Anaganti, S.2
Hainaut, P.3
Olivier, M.4
-
51
-
-
53149122044
-
ERK and JNK mediate TNFalpha-induced p53 activation in apoptotic and autophagic L929 cell death
-
Cheng Y., Qiu F., Tashiro S., Onodera S., Ikejima T. ERK and JNK mediate TNFalpha-induced p53 activation in apoptotic and autophagic L929 cell death. Biochem. Biophys. Res. Commun. 2008, 376:483-488.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.376
, pp. 483-488
-
-
Cheng, Y.1
Qiu, F.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
52
-
-
0032167915
-
MEKK1/JNK signaling stabilizes and activates p53
-
Fuchs S.Y., Adler V., Pincus M.R., Ronai Z. MEKK1/JNK signaling stabilizes and activates p53. Proc. Natl. Acad. Sci. USA 1998, 95:10541-10546.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10541-10546
-
-
Fuchs, S.Y.1
Adler, V.2
Pincus, M.R.3
Ronai, Z.4
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