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Volumn 19, Issue 3, 1999, Pages 1768-1774

Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-jun expression

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

EID: 0033019306     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.3.1768     Document Type: Article
Times cited : (60)

References (52)
  • 1
    • 0024276523 scopus 로고
    • The jun proto-oncogene is positively autoregulated by its product Jun/AP-1
    • Angel, P., K. Bhattari, T. Smeal, and M. Karin. 1988. The jun proto-oncogene is positively autoregulated by its product Jun/AP-1. Cell 55:875-885.
    • (1988) Cell , vol.55 , pp. 875-885
    • Angel, P.1    Bhattari, K.2    Smeal, T.3    Karin, M.4
  • 2
    • 85038205480 scopus 로고    scopus 로고
    • Personal communication
    • Angel, P. Personal communication.
    • Angel, P.1
  • 3
    • 0028029445 scopus 로고
    • PI 3-kinase activation is required for insulin stimulation of glucose transport into L6 myotubes
    • Berger, J., N. Hayes, D. M. Szalkowski, and B. Zhang. 1994. PI 3-kinase activation is required for insulin stimulation of glucose transport into L6 myotubes. Biochem. Biophys. Res. Commun. 205:570-576.
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 570-576
    • Berger, J.1    Hayes, N.2    Szalkowski, D.M.3    Zhang, B.4
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0030597239 scopus 로고    scopus 로고
    • Three paths to stress relief
    • Canman, C. E., and M. B. Kastan. 1996. Three paths to stress relief. Nature 384:213-214.
    • (1996) Nature , vol.384 , pp. 213-214
    • Canman, C.E.1    Kastan, M.B.2
  • 6
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 7
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso, A. A., M. Chiariello, J.-C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Miki, and J. S. Gutkind. 1995. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81:1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, A.A.1    Chiariello, M.2    Yu, J.-C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 8
    • 0030610472 scopus 로고    scopus 로고
    • Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C
    • Das, K. C., and C. W. White. 1997. Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C. J. Biol. Chem. 272:14914-14920.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14914-14920
    • Das, K.C.1    White, C.W.2
  • 9
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV-light and Ha-ras that binds and phosphorylates the c-jun activation domain
    • Derijard, B., M. Hibi, I. H. Wu, T. Barrett, T. Deng, M. Karin, and R. J. Davis. 1994. JNK1: a protein kinase stimulated by UV-light and Ha-ras that binds and phosphorylates the c-jun activation domain. Cell 76:1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Deng, T.5    Karin, M.6    Davis, R.J.7
  • 10
  • 11
    • 0032502772 scopus 로고    scopus 로고
    • Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli
    • Foltz, I. N., R. E. Gerl, J. S. Wieler, M. Luckach, R. A. Salmon, and J. W. Schrader. 1998. Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli. J. Biol. Chem. 273:9344-9351.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9344-9351
    • Foltz, I.N.1    Gerl, R.E.2    Wieler, J.S.3    Luckach, M.4    Salmon, R.A.5    Schrader, J.W.6
  • 13
    • 0031057098 scopus 로고    scopus 로고
    • High-dose selection with mafosfamide results in sensitivity to DNA cross-linking agents: Characterization of hypersensitive cell lines
    • Fritz, G., J. G. Hengstler, and B. Kaina. 1997. High-dose selection with mafosfamide results in sensitivity to DNA cross-linking agents: characterization of hypersensitive cell lines. Cancer Res. 57:454-460.
    • (1997) Cancer Res. , vol.57 , pp. 454-460
    • Fritz, G.1    Hengstler, J.G.2    Kaina, B.3
  • 14
    • 0028849261 scopus 로고
    • The Ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA-damaging treatments
    • Fritz, G., B. Kaina, and K. Aktories. 1995. The Ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA-damaging treatments. J. Biol. Chem. 270:25172-25177.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25172-25177
    • Fritz, G.1    Kaina, B.2    Aktories, K.3
  • 16
    • 0028905076 scopus 로고
    • Transcription factor ATF-2 regulation by the JNK signal transduction pathway
    • Gupta, S., D. Campbell, B. Derijard, and R. J. Davis. 1995. Transcription factor ATF-2 regulation by the JNK signal transduction pathway. Science 267:389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Derijard, B.3    Davis, R.J.4
  • 17
    • 0029030428 scopus 로고
    • c-Fos is involved in the cellular defense against the genotoxic effect of UV radiation
    • Haas, S., and B. Kaina. 1995. c-Fos is involved in the cellular defense against the genotoxic effect of UV radiation. Carcinogenesis 16:985-991.
    • (1995) Carcinogenesis , vol.16 , pp. 985-991
    • Haas, S.1    Kaina, B.2
  • 20
    • 0028303875 scopus 로고
    • Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV-irradiation
    • Herr, I., G. van Dam, and P. Angel. 1994. Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV-irradiation. Carcinogenesis 15:1105-1113.
    • (1994) Carcinogenesis , vol.15 , pp. 1105-1113
    • Herr, I.1    Van Dam, G.2    Angel, P.3
  • 21
    • 0030670626 scopus 로고    scopus 로고
    • Activation of CD95 (APO-1/Fas) signaling by ceramide mediated cancer-therapy induced apoptosis
    • Herr, I., D. Wilhelm, T. Böhler, P. Angel, and K.-M. Debatin. 1997. Activation of CD95 (APO-1/Fas) signaling by ceramide mediated cancer-therapy induced apoptosis. EMBO J. 16:6200-6208.
    • (1997) EMBO J. , vol.16 , pp. 6200-6208
    • Herr, I.1    Wilhelm, D.2    Böhler, T.3    Angel, P.4    Debatin, K.-M.5
  • 22
    • 0344504252 scopus 로고
    • Radiation-induced expression of the c-fos proto-oncogene in normal and tumour-derived cell lines
    • J. D. Chapman, W. C. Dewey, and G. F. Whitmore (ed.). Academic Press, Inc., San Diego, Calif.
    • Herskind, C., M. Flentje, P. Peschke, W. J. Lorenz, and E. W. Hahn. 1991. Radiation-induced expression of the c-fos proto-oncogene in normal and tumour-derived cell lines. In J. D. Chapman, W. C. Dewey, and G. F. Whitmore (ed.), Radiation research: a twentieth century perspective, vol. 1. Academic Press, Inc., San Diego, Calif.
    • (1991) Radiation Research: A Twentieth Century Perspective , vol.1
    • Herskind, C.1    Flentje, M.2    Peschke, P.3    Lorenz, W.J.4    Hahn, E.W.5
  • 23
    • 0026453516 scopus 로고
    • Embryonic stem (ES) cells lacking functional c-jun: Consequences for growth and differentiation, AP-1 activity and tumorigenicity
    • Hilberg, F., and E. F. Wagner. 1992. Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity. Oncogene 7:2371-2380.
    • (1992) Oncogene , vol.7 , pp. 2371-2380
    • Hilberg, F.1    Wagner, E.F.2
  • 24
    • 0029969725 scopus 로고    scopus 로고
    • Ultraviolet B-induced activator protein-1 activation does not require epidermal growth factor receptor but is blocked by a dominant negative PKClambda/iota
    • Huang, C., W. Ma, G. T. Bowden, and Z. Dong. 1996. Ultraviolet B-induced activator protein-1 activation does not require epidermal growth factor receptor but is blocked by a dominant negative PKClambda/iota. J. Biol. Chem. 271:31262-31268.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31262-31268
    • Huang, C.1    Ma, W.2    Bowden, G.T.3    Dong, Z.4
  • 25
    • 0030665792 scopus 로고    scopus 로고
    • Proteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinase, c-Jun N-terminal kinases and p38 kinase
    • Huang, C., W.-Y. Ma, C. A. Ryan, and Z. Dong. 1997. Proteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinase, c-Jun N-terminal kinases and p38 kinase. Proc. Natl. Acad. Sci. USA 94:11957-11962.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11957-11962
    • Huang, C.1    Ma, W.-Y.2    Ryan, C.A.3    Dong, Z.4
  • 26
    • 0027340278 scopus 로고
    • 6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: New insights gained from studies of genetically engineered mammalian cell lines
    • 6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines. Environ. Mol. Mutagen. 22:283-292.
    • (1993) Environ. Mol. Mutagen. , vol.22 , pp. 283-292
    • Kaina, B.1    Fritz, G.2    Coquerelle, T.3
  • 27
    • 0030802033 scopus 로고    scopus 로고
    • A general role for c-Fos in cellular protection against DNA-damaging carcinogens and cytostatic drugs
    • Kaina, B., S. Haas, and H. Kappes. 1997. A general role for c-Fos in cellular protection against DNA-damaging carcinogens and cytostatic drugs. Cancer Res. 57:2721-2731.
    • (1997) Cancer Res. , vol.57 , pp. 2721-2731
    • Kaina, B.1    Haas, S.2    Kappes, H.3
  • 28
    • 0029790979 scopus 로고    scopus 로고
    • Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
    • Knebel, A., H. J. Rahmsdorf, A. Ullrich, and P. Herrlich. 1996. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO J. 15:5314-5325.
    • (1996) EMBO J. , vol.15 , pp. 5314-5325
    • Knebel, A.1    Rahmsdorf, H.J.2    Ullrich, A.3    Herrlich, P.4
  • 29
  • 30
    • 0029034251 scopus 로고
    • ATF-2 contains a phosphorylation-dependent transcriptional activation domain
    • Livingstone, C., G. Patel, and N. Jones. 1995. ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J. 14:1785-1797.
    • (1995) EMBO J. , vol.14 , pp. 1785-1797
    • Livingstone, C.1    Patel, G.2    Jones, N.3
  • 31
    • 0029070887 scopus 로고
    • Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
    • Minden, A., A. Lin, F.-X. Claret, A. Abo, and M. Karin. 1995. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81:1147-1157.
    • (1995) Cell , vol.81 , pp. 1147-1157
    • Minden, A.1    Lin, A.2    Claret, F.-X.3    Abo, A.4    Karin, M.5
  • 33
    • 0030787558 scopus 로고    scopus 로고
    • Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY-294002) on N-formyl-methyionyl-leucyl-phenylanine-induced phospholipase D activation in differentiated HL60 cells: Possible involvement of phosphatidyl 3-kinase in phospholipase D activation
    • Nakamura, M., S. Nakashima, Y. Katagiri, and Y. Nozawa. 1997. Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY-294002) on N-formyl-methyionyl-leucyl-phenylanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidyl 3-kinase in phospholipase D activation. Biochem. Pharmacol. 53:1929-1936.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 1929-1936
    • Nakamura, M.1    Nakashima, S.2    Katagiri, Y.3    Nozawa, Y.4
  • 35
    • 0028124189 scopus 로고
    • Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes
    • Okada, T., Y. Kawano, T. Sakakibara, O. Hazeki, and M. Ui. 1994. Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. J. Biol. Chem. 269:3568-3573.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3568-3573
    • Okada, T.1    Kawano, Y.2    Sakakibara, T.3    Hazeki, O.4    Ui, M.5
  • 36
    • 0028146616 scopus 로고
    • Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase
    • Okada, T., L. Sakuma, Y. Fukui, O. Hazeki, and M. Ui. 1994. Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J. Biol. Chem. 269:3536-3567.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3536-3567
    • Okada, T.1    Sakuma, L.2    Fukui, Y.3    Hazeki, O.4    Ui, M.5
  • 37
    • 0029851730 scopus 로고    scopus 로고
    • Role of the stress-activated c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs
    • Osborne, M. T., and T. C. Chambers. 1996. Role of the stress-activated c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J. Biol. Chem. 271:30950-30955.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30950-30955
    • Osborne, M.T.1    Chambers, T.C.2
  • 38
    • 0029320454 scopus 로고
    • Pl 3-kinase puts GTP on the Rac
    • Parker, P. J. 1995. Pl 3-kinase puts GTP on the Rac. Curr. Biol. 5:577-579.
    • (1995) Curr. Biol. , vol.5 , pp. 577-579
    • Parker, P.J.1
  • 39
    • 0029827366 scopus 로고    scopus 로고
    • The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light
    • Price, M. A., F. H. Cruzalegui, and R. Treisman. 1996. The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J. 23:6552-6563.
    • (1996) EMBO J. , vol.23 , pp. 6552-6563
    • Price, M.A.1    Cruzalegui, F.H.2    Treisman, R.3
  • 42
    • 0029860936 scopus 로고    scopus 로고
    • Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
    • Rosette, C., and M. Karin. 1996. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274:1194-1197.
    • (1996) Science , vol.274 , pp. 1194-1197
    • Rosette, C.1    Karin, M.2
  • 44
    • 0028818599 scopus 로고
    • Fos is an essential component of the mammalian UV response
    • Schreiber, M., B. Baumann, M. Cotton, P. Angel, and E. F. Wagner. 1995. Fos is an essential component of the mammalian UV response. EMBO J. 14:5338-5349.
    • (1995) EMBO J. , vol.14 , pp. 5338-5349
    • Schreiber, M.1    Baumann, B.2    Cotton, M.3    Angel, P.4    Wagner, E.F.5
  • 46
  • 47
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
    • Smeal, T., B. Binetruy, D. A. Mercola, M. Birrer, and M. Karin. 1991. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354:494-496.
    • (1991) Nature , vol.354 , pp. 494-496
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 49
    • 0029030855 scopus 로고
    • ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic stress
    • van Dam, H., D. Wilhelm, I. Herr, A. Steffen, P. Herrlich, and P. Angel. 1995. ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic stress. EMBO J. 14:1798-1811.
    • (1995) EMBO J. , vol.14 , pp. 1798-1811
    • Van Dam, H.1    Wilhelm, D.2    Herr, I.3    Steffen, A.4    Herrlich, P.5    Angel, P.6
  • 50
    • 0029938805 scopus 로고    scopus 로고
    • Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase
    • Wang, X. Z., and D. Ron. 1996. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 272:1347-1349.
    • (1996) Science , vol.272 , pp. 1347-1349
    • Wang, X.Z.1    Ron, D.2
  • 51
    • 0030789179 scopus 로고    scopus 로고
    • The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents
    • Wilhelm, D., K. Bender, A. Knebel, and P. Angel. 1997. The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol. Cell. Biol. 17:4792-4800.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4792-4800
    • Wilhelm, D.1    Bender, K.2    Knebel, A.3    Angel, P.4
  • 52
    • 0030908341 scopus 로고    scopus 로고
    • Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation and defects in AP-1 transcriptional activity
    • Yang, D., C. Tournier, M. Wysk, H.-T. Lu, J. Xu, R. J. Davies, and R. A. Flavell. 1997. Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation and defects in AP-1 transcriptional activity. Proc. Natl. Acad. Sci. USA 94:3004-3009.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3004-3009
    • Yang, D.1    Tournier, C.2    Wysk, M.3    Lu, H.-T.4    Xu, J.5    Davies, R.J.6    Flavell, R.A.7


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