Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction

Molecular and Cellular Biology

Volumn 18, Issue 4, 1998, Pages 1844-1854

  Hazzalin, Catherine A ^a   Le Panse, Rozen ^a   Cano, Eva ^a   Mahadevan, Louis C ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOMYCIN; BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; ENZYME ACTIVATION; GENE INDUCTION; HYPEROSMOLARITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; STRESS; TRANSLATION REGULATION; ULTRAVIOLET RADIATION;

ANIMALIA; MAMMALIA; SACCHAROMYCES; STREPTOMYCES;

EID: 0031896910     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.4.1844     Document Type: Article

References (68)

1. Bagrodia, S., B. Dérijard, R. J. Davis, and R. A. Cerione. 1995. Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 270:27995-27998.
2. Barbacid, M., and D. Vázquez. 1975. Ribosome changes during translation. J. Mol. Biol. 93:449-463.
3. Bowen-Pope, D. F., P. E. DiCorleto, and R. Ross. 1983. Interactions between the receptors for platelet-derived growth factor and epidermal growth factor. J. Cell Biol. 96:679-683.
4. Brown, E. J., M. W. Albers, T. B. Shin, K. Ichikawa, C. T. Keith, W. T. Lane, and S. L. Schreiber. 1994. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature 369:756-758.
5. Brown, E. J., P. A. Beal, C. T. Keith, J. Chen, T. B. Shin, and S. L. Schreiber. 1995. Control of p70 S6 kinase by kinase activity of FRAP in vivo. Nature 377:441-446.
6. Brunet, A., G. Pages, and J. Pouyssegur. 1994. Growth factor-stimulated MAP kinase induces rapid retro-phosphorylation and inhibition of MEK1. FEBS Lett. 346:299-303.
7. Cano, E., and L. C. Mahadevan. 1995. Parallel signal processing among mammalian MAPKs. Trends Biochem. Sci. 20:117-122.
8. Cano, E., C. A. Hazzalin, and L. C. Mahadevan. 1994. Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun. Mol. Cell. Biol. 14:7352-7362.
9. Cano, E., C. A. Hazzalin, E. Kardalinou, R. S. Buckle, and L. C. Mahadevan. 1995. Neither ERK nor JNK/SAPK MAP kinase subtypes are essential for histonc H3/HMG-14 phosphorylation or c-fos and c-jun induction. J. Cell Sci. 108:3599-3609.
10. Cano, E., Y. N. Doza, R. Ben-Levy, P. Cohen, and L. C. Mahadevan. 1996. Identification of anisomycin-activated kinases p45 and p55 in murine cells as MAPKAP kinase-2. Oncogene 12:805-812.
11. Cano, E., R. Le Panse, and L. C. Mahadevan. Unpublished data.
12. Cano, E. C., and L. C. Mahadevan. Unpublished data.
13. Chen, D., S. B. Waters, K. H. Holt, and J. E. Pessin. 1996. SOS phosphorylation and dissociation of the Grb2-SOS complex by the ERK and JNK signaling pathways. J. Biol. Chem. 271:6328-6332.
14. Chomczynski, P. 1992. One-hour downward alkaline capillary transfer for blotting of DNA and RNA. Anal. Biochem. 201:134-139.
15. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
16. Chung, J., C. J. Kuo, G. R. Crabtree, and J. Blenis. 1992. Rapamycin-FKBP specifically blocks growth-dependent activation of and signalling by the 70kDa S6 protein kinases. Cell 69:1227-1236.
17. Church, G. M., and W. Gilbert. 1984. Genomic sequencing. Proc. Natl. Acad. Sci. USA 81:1991-1995.
18. Collins, M. K. L., and E. Rozengurt. 1984. Homologous and heterologous desensitization of Swiss 3T3 cells to phorbol esters and vasopressin: role of receptor and postreceptor sites. J. Cell. Physiol. 118:133-142.
19. Collins, M. K. L., J. W. Sinnett-Smith, and E. Rozengurt. 1983. Platelet-derived growth factor treatment decreases the affinity of the epidermal growth factor receptors of Swiss 3T3 cells. J. Biol. Chem. 258:1689-1693.
20. Coso, O. A., M. Chiariello, J.-C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Miki, and J. S. Gutkind. 1995. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81:1137-1146.
21. Curran, T., G. Peters, C. Van Beveren, N. M. Teich, and I. M. Verma. 1982. FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. J. Virol. 44:674-682.
22. Dai, T., E. Ruble, C. C. Franklin, A. Kraft, D. A. F. Gillespie, J. Avruch, J. M. Kyriakis, and J. R. Woodgett. 1995. Stress-activated protein kinases bind directly to the δ domain of c-Jun in resting cells: implications for repression of c-Jun function. Oncogene 10:849-855.
23. Davis, R. J., and M. P. Czech. 1985. Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine 654. Proc. Natl. Acad. Sci. USA 82:4080-4084.
24. Dérijard, B., M. Hibi, I.-H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
25. Edwards, D. R., and L. C. Mahadevan. 1992. Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors. EMBO J. 11:2415-2424.
26. Edwards, L. C., and L. C. Mahadevan. Unpublished data.
27. Gille, H., T. Strahl, and P. E. Shaw. 1995. Activation of ternary complex factor Elk-1 by stress-activated protein kinases. Curr. Biol. 5:1191-1200.
28. 24a. Hazzalin, C. A. 1996. Ph.D. thesis. University of London, London, England.
29. Hazzalin, C. A., E. Cano, A. Cuenda, M. J. Barratt, P. Cohen, and L. C. Mahadevan. 1996. p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient. Curr. Biol. 6:1028-1031.
30. Hazzalin, C. A., A. Cuenda, E. Cano, P. Cohen, and L. C. Mahadevan. 1997. Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli. Oncogene 15:2321-2331.
31. 26a. Hazzalin, C. A., and L. C. Mahadevan. Unpublished data.
32. Heath, J. K., L. Mahadevan, and J. G. Foulkes. 1986. The role of EGF receptor transmodulation in embryonal carcinoma-derived growth factor-induced mitogenesis. EMBO J. 5:1809-1814.
33. Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7:2135-2148.
34. Iordanov, M. S., D. Pribnow, J. L. Magun, T. H. Dinh, J. A. Pearson, S. L. Chen, and B. E. Magun. 1997. Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the α-sarcin/ricin loop in the 28S rRNA. Mol. Cell. Biol. 17:3373-3381.
35. Jiménez, A., and D. Vázquez. 1979. Anisomycin and related antibiotics, p. 1-19. In F. E. Hahn (ed.), Antibiotics, vol. 5, part 2. Springer-Verlag, New York, N.Y.
36. S6k containing a bifurcation to histone H3-HMG-like protein phosphorylation and c-fos-c-jun induction. Mol. Cell. Biol. 14:1066-1074.
37. Keyse, S. M., and E. A. Emslie. 1992. Oxidative stress and heat shock induce a gene encoding a protein-tyrosine phosphatase. Nature 359:644-647.
38. König, H., H. Ponta, U. Rahmsdorf, M. Büscher, A. Schönthal, H. J. Rahmsdorf, and P. Herrlich. 1989. Autoregulation of fos: the dyad symmetry element as the major target of repression. EMBO J. 8:2559-2566.
39. Kyriakis, J. M., P. Banerjee, E. Nikolakaki, T. Dai, E. A. Rubie, M. F. Ahmad, J. Avruch, and J. R. Woodgett. 1994. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369:156-160.
40. ras activation. J. Biol. Chem. 270:25320-25323.
41. Le Panse, R., and L. C. Mahadevan. Unpublished data.
42. Liu, J., S. Mathias, Z. H. Yang, and R. N. Kolesnick. 1994. Renaturation and tumor necrosis factor-α stimulation of a 97-kDa ceramide-activated protein kinase. J. Biol. Chem. 269:3047-3052.
43. Liu, Y., M. Gorospe, C. Yang, and N. J. Holbrook. 1995. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. J. Biol. Chem. 270:8377-8380.
44. Lucibello, F. C., C. Lowag, M. Neuberg, and R. Müller. 1989. Trans-repression of the mouse c-fos promoter: a novel mechanism of fos-mediated transregulation. Cell 59:999-1007.
45. Mahadevan, L. C., and D. R. Edwards. 1991. Signalling and superinduction. Nature 349:747-748.
46. Mahadevan, L. C., A. C. Willis, and M. J. Barratt. 1991. Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors. Cell 65:775-783.
47. Manser, E., T. Leung, H. Salihuddin, Z.-S. Zhao, and L. Lim. 1994. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367: 40-46.
48. Meier, R., J. Rouse, A. Cuenda, A. R. Nebreda, and P. Cohen. 1996. Cellular stresses and cytokines activate multiple mitogcn-activated protein kinase kinase homologues in PC12 and KB cells. Eur. J. Biochem. 236:796-805.
49. Minden, A., A. Lin, F.-X. Claret, A. Abo, and M. Karin. 1995. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Racand Cdc42Hs. Cell 81:1147-1157.
50. 1. Science 269:1270-1272.
51. Pombo, C. M., J. H. Kehrl, I. Sánchez, P. Katz, J. Avruch, L. I. Zon, J. R. Woodgett, T. Force, and J. M. Kyriakis. 1995. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase. Nature 377:750-754.
52. Rivera, V. M., M. Sheng, and M. E. Greenberg. 1990. The inner core of the serum response element mediates both the rapid induction and subsequent repression of c-fos transcription following serum stimulation. Genes Dev. 4:255-268.
53. Rosette, C., and M. Karin. 1996. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274:1194-1197.
54. Ryder, K., A. Lanahan, E. Perez-Albuerne, and D. Nathans. 1989. Jun-D: a third member of the Jun gene family. Proc. Natl. Acad. Sci. USA 86:1500-1503.
55. 1 transition in mouse fibroblasts. Nature 334:535-537.
56. Sachsenmaier, C., A. Radler-Pohl, R. Zinck, A. Nordheim, P. Herrlich, and H. J. Rahmsdorf. 1994. Involvement of growth factor receptors in the mammalian UVC response. Cell 78:963-972.
57. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
58. Sánchez, I., R. T. Hughes, B. J. Mayer, K. Yee, J. R. Woodgett, J. Avruch, J. M. Kyriakis, and L. I. Zon. 1994. Role of SAPK/ERK kinase-1 in the stress activated pathway regulating transcription factor c-Jun. Nature 372:794-798.
59. Sassone-Corsi, P., J. C. Sisson, and I. M. Verma. 1988. Transcriptional autoregulation of the proto-oncogene fos. Nature 334:314-319.
60. Sobin, B. A., and F. W. Tanner, Jr. 1954. Anisomycin, a new antiprotozoan antibiotic. J. Am. Chem. Soc. 76:4053.
61. Subramaniam, M., L. J. Schmidt, C. E. Crutchfield III, and M. J. Getz. 1989. Negative regulation of serum-responsive enhancer elements. Nature 340:64-70.
62. Sun, H., C. H. Charles, L. F. Lau, and N. K. Tonks. 1993. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 75:487-493.
63. Ueki, K., S. Matsuda, K. Tobe, Y. Gotoh, H. Tamemoto, M. Yachi, Y. Akanuma, Y. Yazaki, E. Nishida, and T. Kadowaki. 1994. Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation. J. Biol. Chem. 269:15756-15761.
64. Wu, J., P. Dent, T. Jelinek, A. Wolfman, M. J. Weber, and T. W. Sturgill. 1993. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine-3′,5′-monophosphate. Science 262:1065-1069.
65. Young, S., P. J. Parker, A. Ullrich, and S. Stabel. 1987. Down-regulation of protein kinase C is due to an increased rate of degradation. Biochem. J. 244:755-779.
66. Zhang, S., J. Han, M. A. Sells, J. Chernoff, U. G. Knaus, R. J. Ulevitch, and G. M. Bokoch. 1995. Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1. J. Biol. Chem. 270: 23934-23936.
67. Zhelev, N., and L. C. Mahadevan. Unpublished data.
68. Zinck, R., M. A. Cahill, M. Kracht, C. Sachsenmaier, R. A. Hipskind, and A. Nordheim. 1995. Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase and stress-activated protein kinase pathways that converge on Elk-1. Mol. Cell. Biol. 15:4930-4938.