Direct effects of TNF-a on local fuel metabolism and cytokine levels in the placebo-controlled, bilaterally infused human leg increased insulin sensitivity, increased net protein breakdown, and increased il-6 release

Diabetes

Volumn 62, Issue 12, 2013, Pages 4023-4029

  Bach, Ermina ^a,b   Nielsen, Roni R ^a,b   Vendelbo, Mikkel H ^a,b   Møller, Andreas B ^a,b   Jessen, Niels ^a,b   Buhl, Mads ^a,b   Hafstrøm, Thomas K ^a,b   Holm, Lars ^c   Pedersen, Steen B ^a,b   Pilegaard, Henriette ^d   Biensø, Rasmus S ^d   Jørgensen, Jens O L ^a,b   Møller, Niels ^a,b  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c BISPEBJERG HOSPITAL   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GAMMA INTERFERON; GLUCOSE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INSULIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MUSCLE PROTEIN; PHENYLALANINE; SODIUM CHLORIDE; TASONERMIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTERY CATHETER; ARTERY PERFUSION; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG INFUSION; FATTY ACID METABOLISM; FEMORAL ARTERY; FEMORAL VEIN; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAVENOUS CATHETER; LEG BLOOD FLOW; MALE; MUSCLE BIOPSY; MUSCLE METABOLISM; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; RANDOMIZED CONTROLLED TRIAL; SIGNAL TRANSDUCTION; SINGLE BLIND PROCEDURE; YOUNG ADULT;

ADULT; BLOOD GLUCOSE; CYTOKINES; ENERGY METABOLISM; FEMORAL ARTERY; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RESISTANCE; INTERLEUKIN-6; LEG; MALE; MUSCLE, SKELETAL; SINGLE-BLIND METHOD; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84891797626     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0138     Document Type: Article

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