-
1
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG (2000) Obesity as a medical problem. Nature 404:635-643
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
2
-
-
2342625424
-
Increasing prevalence of type 2 diabetes in adolescents
-
Hotu S, Carter B, Watson P, Cutfield W, Cundy T (2004) Increasing prevalence of type 2 diabetes in adolescents. J Paediatr Child Health 40:201-204
-
(2004)
J Paediatr Child Health
, vol.40
, pp. 201-204
-
-
Hotu, S.1
Carter, B.2
Watson, P.3
Cutfield, W.4
Cundy, T.5
-
3
-
-
10744228850
-
Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood
-
Bhargava SK, Sachdev HS, Fall CH et al (2004) Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood. N Engl J Med 350:865-875
-
(2004)
N Engl J Med
, vol.350
, pp. 865-875
-
-
Bhargava, S.K.1
Sachdev, H.S.2
Fall, C.H.3
-
4
-
-
2642568613
-
Obesity: An overview on its current perspectives and treatment options
-
Nammi S, Koka S, Chinnala KM, Boini KM (2004) Obesity: an overview on its current perspectives and treatment options. Nutr J 3:3
-
(2004)
Nutr J
, vol.3
, pp. 3
-
-
Nammi, S.1
Koka, S.2
Chinnala, K.M.3
Boini, K.M.4
-
5
-
-
0028091785
-
Regional adiposity and morbidity
-
Kissebah AH, Krakower GR (1994) Regional adiposity and morbidity. Physiol Rev 74:761-811
-
(1994)
Physiol Rev
, vol.74
, pp. 761-811
-
-
Kissebah, A.H.1
Krakower, G.R.2
-
6
-
-
0027512732
-
Role of insulin resistance in human disease (syndrome X): An expanded definition
-
Reaven GM (1993) Role of insulin resistance in human disease (syndrome X): an expanded definition. Annu Rev Med 44:121-131
-
(1993)
Annu Rev Med
, vol.44
, pp. 121-131
-
-
Reaven, G.M.1
-
7
-
-
0032554512
-
Impairment of health and quality of life in people with large waist circumference
-
Lean ME, Han TS, Seidell JC (1998) Impairment of health and quality of life in people with large waist circumference. Lancet 351:853-856
-
(1998)
Lancet
, vol.351
, pp. 853-856
-
-
Lean, M.E.1
Han, T.S.2
Seidell, J.C.3
-
8
-
-
0028818780
-
Waist circumference action levels in the identification of cardiovascular risk factors: Prevalence study in a random sample
-
Han TS, van Leer EM, Seidell JC, Lean ME (1995) Waist circumference action levels in the identification of cardiovascular risk factors: prevalence study in a random sample. Bmj 311:1401-1405
-
(1995)
Bmj
, vol.311
, pp. 1401-1405
-
-
Han, T.S.1
Van Leer, E.M.2
Seidell, J.C.3
Lean, M.E.4
-
9
-
-
0021678265
-
Distribution of adipose tissue and risk of cardiovascular disease and death: A 12 year follow up of participants in the population study of women in Gothenburg, Sweden
-
Lapidus L, Bengtsson C, Larsson B, Pennert K, Rybo E, Sjostrom L (1984) Distribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden. Br Med J (Clin Res Ed) 289:1257-1261
-
(1984)
Br Med J (Clin Res Ed)
, vol.289
, pp. 1257-1261
-
-
Lapidus, L.1
Bengtsson, C.2
Larsson, B.3
Pennert, K.4
Rybo, E.5
Sjostrom, L.6
-
10
-
-
0023618126
-
Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes
-
Felber JP, Ferrannini E, Golay A et al (1987) Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes. Diabetes 36:1341-1350
-
(1987)
Diabetes
, vol.36
, pp. 1341-1350
-
-
Felber, J.P.1
Ferrannini, E.2
Golay, A.3
-
11
-
-
0026376995
-
Improvement of glucose and lipid metabolism associated with selective reduction of intra-abdominal visceral fat in premenopausal women with visceral fat obesity
-
Fujioka S, Matsuzawa Y, Tokunaga K et al (1991) Improvement of glucose and lipid metabolism associated with selective reduction of intra-abdominal visceral fat in premenopausal women with visceral fat obesity. Int J Obes 15:853-859
-
(1991)
Int J Obes
, vol.15
, pp. 853-859
-
-
Fujioka, S.1
Matsuzawa, Y.2
Tokunaga, K.3
-
12
-
-
0027366130
-
Differential effects of body fatness and body fat distribution on risk factor for cardiovascular disease in women
-
Dennis KE, Goldberg AP (1993) Differential effects of body fatness and body fat distribution on risk factor for cardiovascular disease in women. Impact of weight loss. Arterioscler Thromb 13:1487-1494
-
(1993)
Impact of Weight Loss. Arterioscler Thromb
, vol.13
, pp. 1487-1494
-
-
Dennis, K.E.1
Goldberg, A.P.2
-
13
-
-
0031844155
-
CD36 abnormality and impaired myocardial long-chain fatty acid uptake in patients with hypertrophic cardiomyopathy
-
Okamoto F, Tanaka T, Sohmiya K, Kawamura K (1998) CD36 abnormality and impaired myocardial long-chain fatty acid uptake in patients with hypertrophic cardiomyopathy. Jpn Circ J 62:499-504
-
(1998)
Jpn Circ J
, vol.62
, pp. 499-504
-
-
Okamoto, F.1
Tanaka, T.2
Sohmiya, K.3
Kawamura, K.4
-
14
-
-
0032880826
-
Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells
-
Lefebvre M, Paulweber B, Fajas L et al (1999) Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells. J Endocrinol 162:331-340
-
(1999)
J Endocrinol
, vol.162
, pp. 331-340
-
-
Lefebvre, M.1
Paulweber, B.2
Fajas, L.3
-
15
-
-
0033615353
-
PPARgamma: An essential regulator of adipogenesis and modulator of fat cell function
-
Lowell BB (1999) PPARgamma: an essential regulator of adipogenesis and modulator of fat cell function. Cell 99:239-242
-
(1999)
Cell
, vol.99
, pp. 239-242
-
-
Lowell, B.B.1
-
16
-
-
0035462629
-
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
-
Maeda N, Takahashi M, Funahashi T et al (2001) PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 50:2094-2099
-
(2001)
Diabetes
, vol.50
, pp. 2094-2099
-
-
Maeda, N.1
Takahashi, M.2
Funahashi, T.3
-
17
-
-
0030971880
-
Is CD36 deficiency an etiology of hereditary hypertrophic cardiomyopathy?
-
Tanaka T, Sohmiya K, Kawamura K (1997) Is CD36 deficiency an etiology of hereditary hypertrophic cardiomyopathy? J Mol Cell Cardiol 29:121-127
-
(1997)
J Mol Cell Cardiol
, vol.29
, pp. 121-127
-
-
Tanaka, T.1
Sohmiya, K.2
Kawamura, K.3
-
18
-
-
0030855789
-
Regulation of FAT/CD36 gene expression: Further evidence in support of a role of the protein in fatty acid binding/transport
-
Sfeir Z, Ibrahimi A, Amri E, Grimaldi P, Abumrad N (1997) Regulation of FAT/CD36 gene expression: further evidence in support of a role of the protein in fatty acid binding/transport. Prostaglandins Leukot Essent Fatty Acids 57:17-21
-
(1997)
Prostaglandins Leukot Essent Fatty Acids
, vol.57
, pp. 17-21
-
-
Sfeir, Z.1
Ibrahimi, A.2
Amri, E.3
Grimaldi, P.4
Abumrad, N.5
-
19
-
-
0032938127
-
CD36 antisense expression in 3T3-F442A preadipocytes
-
Sfeir Z, Ibrahimi A, Amri E, Grimaldi P, Abumrad N (1999) CD36 antisense expression in 3T3-F442A preadipocytes. Mol Cell Biochem 192:3-8
-
(1999)
Mol Cell Biochem
, vol.192
, pp. 3-8
-
-
Sfeir, Z.1
Ibrahimi, A.2
Amri, E.3
Grimaldi, P.4
Abumrad, N.5
-
20
-
-
0031687404
-
Stable transfection of fatty acid translocase (CD36) in a rat heart muscle cell line (H9c2)
-
Van Nieuwenhoven FA, Luiken JJ, De Jong YF, Grimaldi PA, van der Vusse GJ, Glatz JF (1998) Stable transfection of fatty acid translocase (CD36) in a rat heart muscle cell line (H9c2). J Lipid Res 39:2039-2047
-
(1998)
J Lipid Res
, vol.39
, pp. 2039-2047
-
-
Van Nieuwenhoven, F.A.1
Luiken, J.J.2
De Jong, Y.F.3
Grimaldi, P.A.4
Van Der Vusse, G.J.5
Glatz, J.F.6
-
21
-
-
0027240176
-
Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36
-
Abumrad NA, el-Maghrabi MR, Amri EZ, Lopez E, Grimaldi PA (1993) Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36. J Biol Chem 268:17665-17668
-
(1993)
J Biol Chem
, vol.268
, pp. 17665-17668
-
-
Abumrad, N.A.1
El-Maghrabi, M.R.2
Amri, E.Z.3
Lopez, E.4
Grimaldi, P.A.5
-
23
-
-
0032854610
-
Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm
-
Abumrad N, Coburn C, Ibrahimi A (1999) Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. Biochim Biophys Acta 1441:4-13
-
(1999)
Biochim Biophys Acta
, vol.1441
, pp. 4-13
-
-
Abumrad, N.1
Coburn, C.2
Ibrahimi, A.3
-
24
-
-
0034923655
-
Role of CD36 in membrane transport and utilization of long-chain fatty acids by different tissues
-
Coburn CT, Hajri T, Ibrahimi A, Abumrad NA (2001) Role of CD36 in membrane transport and utilization of long-chain fatty acids by different tissues. J Mol Neurosci 16:117-21
-
(2001)
J Mol Neurosci
, vol.16
, pp. 117-21
-
-
Coburn, C.T.1
Hajri, T.2
Ibrahimi, A.3
Abumrad, N.A.4
-
25
-
-
0035139016
-
The role of PPAR-gamma in macrophage differentiation and cholesterol uptake
-
Moore KJ, Rosen ED, Fitzgerald ML et al (2001) The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nat Med 7:41-47
-
(2001)
Nat Med
, vol.7
, pp. 41-47
-
-
Moore, K.J.1
Rosen, E.D.2
Fitzgerald, M.L.3
-
26
-
-
26444485985
-
Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle
-
Koonen DP, Glatz JF, Bonen A, Luiken JJ (2005) Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle. Biochim Biophys Acta 1736:163-180
-
(2005)
Biochim Biophys Acta
, vol.1736
, pp. 163-180
-
-
Koonen, D.P.1
Glatz, J.F.2
Bonen, A.3
Luiken, J.J.4
-
27
-
-
0017119837
-
Induction of lipogenesis during differentiation in a " preadipocyte" cell line
-
Mackall JC, Student AK, Polakis SE, Lane MD (1976) Induction of lipogenesis during differentiation in a "preadipocyte" cell line. J Biol Chem 251:6462-6464
-
(1976)
J Biol Chem
, vol.251
, pp. 6462-6464
-
-
MacKall, J.C.1
Student, A.K.2
Polakis, S.E.3
Lane, M.D.4
-
28
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
29
-
-
0020519557
-
Polyoma virus transforming protein associates with the product of the c-src cellular gene
-
Courtneidge SA, Smith AE (1983) Polyoma virus transforming protein associates with the product of the c-src cellular gene. Nature 303:435-439
-
(1983)
Nature
, vol.303
, pp. 435-439
-
-
Courtneidge, S.A.1
Smith, A.E.2
-
30
-
-
0028152492
-
Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein
-
Schaffer JE, Lodish HF (1994) Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell 79:427-436
-
(1994)
Cell
, vol.79
, pp. 427-436
-
-
Schaffer, J.E.1
Lodish, H.F.2
-
31
-
-
0035203991
-
Gut expression and regulation of FAT/CD36: Possible role in fatty acid transport in rat enterocytes
-
Chen M, Yang Y, Braunstein E, Georgeson KE, Harmon CM (2001) Gut expression and regulation of FAT/CD36: possible role in fatty acid transport in rat enterocytes. Am J Physiol Endocrinol Metab 281:E916-E923
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Chen, M.1
Yang, Y.2
Braunstein, E.3
Georgeson, K.E.4
Harmon, C.M.5
-
32
-
-
33646778517
-
Adipose tissue lipolysis as a metabolic pathway to define pharmacological strategies against obesity and the metabolic syndrome
-
Langin D (2006) Adipose tissue lipolysis as a metabolic pathway to define pharmacological strategies against obesity and the metabolic syndrome. Pharmacol Res 53:482-491
-
(2006)
Pharmacol Res
, vol.53
, pp. 482-491
-
-
Langin, D.1
-
33
-
-
0037233828
-
Rapid induction of peroxisome proliferator-activated receptor gamma expression in human monocytes by monosodium urate monohydrate crystals
-
Akahoshi T, Namai R, Murakami Y et al (2003) Rapid induction of peroxisome proliferator-activated receptor gamma expression in human monocytes by monosodium urate monohydrate crystals. Arthritis Rheum 48:231-239
-
(2003)
Arthritis Rheum
, vol.48
, pp. 231-239
-
-
Akahoshi, T.1
Namai, R.2
Murakami, Y.3
-
34
-
-
0346003777
-
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression
-
Yu S, Matsusue K, Kashireddy P et al (2003) Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem 278:498-505
-
(2003)
J Biol Chem
, vol.278
, pp. 498-505
-
-
Yu, S.1
Matsusue, K.2
Kashireddy, P.3
-
35
-
-
0035941270
-
The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages
-
Vosper H, Patel L, Graham TL et al (2001) The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages. J Biol Chem 276:44258-44265
-
(2001)
J Biol Chem
, vol.276
, pp. 44258-44265
-
-
Vosper, H.1
Patel, L.2
Graham, T.L.3
-
36
-
-
0035064809
-
Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents
-
Singh Ahuja H, Liu S, Crombie DL et al (2001) Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents. Mol Pharmacol 59:765-773
-
(2001)
Mol Pharmacol
, vol.59
, pp. 765-773
-
-
Singh Ahuja, H.1
Liu, S.2
Crombie, D.L.3
-
37
-
-
33646239182
-
FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity
-
Wu Q, Ortegon AM, Tsang B, Doege H, Feingold KR, Stahl A (2006) FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity. Mol Cell Biol 26:3455-3467
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3455-3467
-
-
Wu, Q.1
Ortegon, A.M.2
Tsang, B.3
Doege, H.4
Feingold, K.R.5
Stahl, A.6
-
38
-
-
9444254658
-
Regulation of the murine adipocyte fatty acid transporter gene by insulin
-
Man MZ, Hui TY, Schaffer JE, Lodish HF, Bernlohr DA (1996) Regulation of the murine adipocyte fatty acid transporter gene by insulin. Mol Endocrinol 10:1021-1028
-
(1996)
Mol Endocrinol
, vol.10
, pp. 1021-1028
-
-
Man, M.Z.1
Hui, T.Y.2
Schaffer, J.E.3
Lodish, H.F.4
Bernlohr, D.A.5
-
39
-
-
0027967521
-
Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function
-
Unterman TG, Fareeduddin A, Harris MA et al (1994) Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function. Biochem Biophys Res Commun 203:1835-1841
-
(1994)
Biochem Biophys Res Commun
, vol.203
, pp. 1835-1841
-
-
Unterman, T.G.1
Fareeduddin, A.2
Harris, M.A.3
-
40
-
-
0028082289
-
Arachidonic acid down-regulates the insulin-dependent glucose transporter gene (GLUT4) in 3T3-L1 adipocytes by inhibiting transcription and enhancing mRNA turnover
-
Tebbey PW, McGowan KM, Stephens JM, Buttke TM, Pekala PH (1994) Arachidonic acid down-regulates the insulin-dependent glucose transporter gene (GLUT4) in 3T3-L1 adipocytes by inhibiting transcription and enhancing mRNA turnover. J Biol Chem 269:639-644
-
(1994)
J Biol Chem
, vol.269
, pp. 639-644
-
-
Tebbey, P.W.1
McGowan, K.M.2
Stephens, J.M.3
Buttke, T.M.4
Pekala, P.H.5
-
41
-
-
0028860340
-
Hepatic nuclear factor 3-and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes
-
O'Brien RM, Noisin EL, Suwanichkul A et al (1995) Hepatic nuclear factor 3-and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes. Mol Cell Biol 15:1747-1758
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1747-1758
-
-
O'Brien, R.M.1
Noisin, E.L.2
Suwanichkul, A.3
-
42
-
-
0027465113
-
Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes
-
Spiegelman BM, Choy L, Hotamisligil GS, Graves RA, Tontonoz P (1993) Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes. J Biol Chem 268:6823-6826
-
(1993)
J Biol Chem
, vol.268
, pp. 6823-6826
-
-
Spiegelman, B.M.1
Choy, L.2
Hotamisligil, G.S.3
Graves, R.A.4
Tontonoz, P.5
-
43
-
-
0029855844
-
Enhanced sympathetic nervous system activity. the linchpin between insulin resistance, hyperinsulinemia, and heart rate
-
Facchini FS, Stoohs RA, Reaven GM (1996) Enhanced sympathetic nervous system activity. The linchpin between insulin resistance, hyperinsulinemia, and heart rate. Am J Hypertens 9:1013-1017
-
(1996)
Am J Hypertens
, vol.9
, pp. 1013-1017
-
-
Facchini, F.S.1
Stoohs, R.A.2
Reaven, G.M.3
-
44
-
-
0032449219
-
The genetic basis of type 2 diabetes mellitus: Impaired insulin secretion versus impaired insulin sensitivity
-
Gerich JE (1998) The genetic basis of type 2 diabetes mellitus: impaired insulin secretion versus impaired insulin sensitivity. Endocr Rev 19:491-503
-
(1998)
Endocr Rev
, vol.19
, pp. 491-503
-
-
Gerich, J.E.1
-
45
-
-
0037643536
-
Effects of free fatty acids (FFA) on glucose metabolism: Significance for insulin resistance and type 2 diabetes
-
Boden G (2003) Effects of free fatty acids (FFA) on glucose metabolism: significance for insulin resistance and type 2 diabetes. Exp Clin Endocrinol Diabetes 111:121-124
-
(2003)
Exp Clin Endocrinol Diabetes
, vol.111
, pp. 121-124
-
-
Boden, G.1
-
46
-
-
0034682780
-
Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes
-
Fasshauer M, Klein J, Ueki K et al (2000) Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes. J Biol Chem 275:25494-25501
-
(2000)
J Biol Chem
, vol.275
, pp. 25494-25501
-
-
Fasshauer, M.1
Klein, J.2
Ueki, K.3
-
47
-
-
0034749546
-
Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes
-
Fasshauer M, Klein J, Kriauciunas KM, Ueki K, Benito M, Kahn CR (2001) Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes. Mol Cell Biol 21:319-329
-
(2001)
Mol Cell Biol
, vol.21
, pp. 319-329
-
-
Fasshauer, M.1
Klein, J.2
Kriauciunas, K.M.3
Ueki, K.4
Benito, M.5
Kahn, C.R.6
-
48
-
-
0035625679
-
Structural and functional characterization of the mouse fatty acid translocase promoter: Activation during adipose differentiation
-
Teboul L, Febbraio M, Gaillard D, Amri EZ, Silverstein R, Grimaldi PA (2001) Structural and functional characterization of the mouse fatty acid translocase promoter: activation during adipose differentiation. Biochem J 360:305-312
-
(2001)
Biochem J
, vol.360
, pp. 305-312
-
-
Teboul, L.1
Febbraio, M.2
Gaillard, D.3
Amri, E.Z.4
Silverstein, R.5
Grimaldi, P.A.6
|