TLR9 Activation Is Triggered by the Excess of Stimulatory versus Inhibitory Motifs Present in Trypanosomatidae DNA

PLoS Neglected Tropical Diseases

Volumn 8, Issue 11, 2014, Pages

  Khan, Mélissa Erin ^a   Borde, Chloé ^a   Rocha, Eduardo P C ^a,b   Mériaux, Véronique ^a   Maréchal, Vincent ^c   Escoll, Pedro ^a   Goyard, Sophie ^a   Cavaillon, Jean Marc ^a   Manoury, Bénédicte ^d   Doyen, Noëlle ^a  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; DNA; PROTOZOAL DNA;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; CELL INTERACTION; CELL STIMULATION; CELLULAR DISTRIBUTION; CYTOLYSIS; DNA PROTEIN COMPLEX; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENOME ANALYSIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; KINETOPLASTIDA; LEISHMANIA MAJOR; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; TRYPANOSOMA VIVAX; WESTERN BLOTTING; ANIMAL; BONE MARROW CELL; C57BL MOUSE; CHEMISTRY; DENDRITIC CELL; FEMALE; GENETICS; GENOME; IMMUNOLOGY; METABOLISM; NUCLEOTIDE MOTIF; PARASITOLOGY; PIG; SHEEP; TRYPANOSOMATIDAE;

ANIMALS; BONE MARROW CELLS; DENDRITIC CELLS; DNA; DNA, PROTOZOAN; FEMALE; GENOME, PROTOZOAN; HUMANS; MICE; MICE, INBRED C57BL; NUCLEOTIDE MOTIFS; SHEEP; SIGNAL TRANSDUCTION; SWINE; TOLL-LIKE RECEPTOR 9; TRYPANOSOMATINA;

EID: 84920480027     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003308     Document Type: Article

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