메뉴 건너뛰기




Volumn 288, Issue 10, 2013, Pages 7127-7136

UNC93B1 and nucleic acid-sensing toll-like receptors mediate host resistance to infection with leishmania major

Author keywords

[No Author keywords available]

Indexed keywords

CRITICAL ELEMENTS; HOST RESISTANCE; KNOCK OUTS; LEISHMANIA; LEISHMANIA MAJOR; TOLL-LIKE RECEPTORS;

EID: 84874881680     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.407684     Document Type: Article
Times cited : (34)

References (38)
  • 1
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • DOI 10.1038/nri933
    • Sacks, D., and Noben-Trauth, N. (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2, 845-858 (Pubitemid 37328707)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.11 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 2
    • 0024236111 scopus 로고
    • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
    • DOI 10.1084/jem.168.5.1675
    • Scott, P., Natovitz, P., Coffman, R. L., Pearce, E., and Sher, A. (1988) Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J. Exp. Med. 168, 1675-1684 (Pubitemid 19023255)
    • (1988) Journal of Experimental Medicine , vol.168 , Issue.5 , pp. 1675-1684
    • Scott, P.1    Natovitz, P.2    Coffman, R.L.3    Pearce, E.4    Sher, A.5
  • 3
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon γ or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets
    • DOI 10.1084/jem.169.1.59
    • Heinzel, F. P., Sadick, M. D., Holaday, B. J., Coffman, R. L., and Locksley, R. M. (1989) Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J. Exp. Med. 169, 59-72 (Pubitemid 19035542)
    • (1989) Journal of Experimental Medicine , vol.169 , Issue.1 , pp. 59-72
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Coffman, R.L.4    Locksley, R.M.5
  • 6
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
    • Scharton-Kersten, T., Afonso, L. C., Wysocka, M., Trinchieri, G., and Scott, P. (1995) IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154, 5320-5330
    • (1995) J. Immunol. , vol.154 , pp. 5320-5330
    • Scharton-Kersten, T.1    Afonso, L.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 8
    • 0038560975 scopus 로고    scopus 로고
    • The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major
    • Noben-Trauth, N., Lira, R., Nagase, H., Paul, W. E., and Sacks, D. L. (2003) The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major. J. Immunol. 170, 5152-5158 (Pubitemid 36554747)
    • (2003) Journal of Immunology , vol.170 , Issue.10 , pp. 5152-5158
    • Noben-Trauth, N.1    Lira, R.2    Nagase, H.3    Paul, W.E.4    Sacks, D.L.5
  • 9
    • 0035863867 scopus 로고    scopus 로고
    • The role of IL-10 in promoting disease progression in Leishmaniasis
    • Kane, M. M., and Mosser, D. M. (2001) The role of IL-10 in promoting disease progression in leishmaniasis. J. Immunol. 166, 1141-1147 (Pubitemid 32060273)
    • (2001) Journal of Immunology , vol.166 , Issue.2 , pp. 1141-1147
    • Kane, M.M.1    Mosser, D.M.2
  • 10
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
    • Akira, S., Uematsu, S., and Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124, 783-801 (Pubitemid 43261452)
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 11
  • 12
    • 0345714673 scopus 로고    scopus 로고
    • High Levels of Susceptibility and T Helper 2 Response in MyD88-Deficient Mice Infected with Leishmania major Are Interleukin-4 Dependent
    • DOI 10.1128/IAI.71.12.7215-7218.2003
    • Debus, A., Gläsner, J., Röllinghoff, M., and Gessner, A. (2003) High levels of susceptibility and T helper 2 response in MyD88-deficient mice infected with Leishmania major are interleukin-4 dependent. Infect. Immun. 71, 7215-7218 (Pubitemid 37475361)
    • (2003) Infection and Immunity , vol.71 , Issue.12 , pp. 7215-7218
    • Debus, A.1    Glasner, J.2    Rollinghoff, M.3    Gessner, A.4
  • 13
    • 0037446651 scopus 로고    scopus 로고
    • Genetically resistant mice lacking MyD88-adapter protein display a high susceptibility to Leishmania major infection associated with a polarized Th2 response
    • Muraille, E., De Trez, C., Brait, M., De Baetselier, P., Leo, O., and Carlier, Y. (2003) Genetically resistant mice lacking MyD88-adapter protein display a high susceptibility to Leishmania major infection associated with a polarized Th2 response. J. Immunol. 170, 4237-4241 (Pubitemid 36428190)
    • (2003) Journal of Immunology , vol.170 , Issue.8 , pp. 4237-4241
    • Muraille, E.1    De Trez, C.2    Brait, M.3    De Baetselier, P.4    Leo, O.5    Carlier, Y.6
  • 14
    • 77953296406 scopus 로고    scopus 로고
    • The MyD88 protein 88 pathway is differently involved in immune responses induced by distinct substrains of Leishmania major
    • Revaz-Breton, M., Ronet, C., Ives, A., Torre, Y. H., Masina, S., Tacchini-Cottier, F., and Launois, P. (2010) The MyD88 protein 88 pathway is differently involved in immune responses induced by distinct substrains of Leishmania major. Eur. J. Immunol. 40, 1697-1707
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1697-1707
    • Revaz-Breton, M.1    Ronet, C.2    Ives, A.3    Torre, Y.H.4    Masina, S.5    Tacchini-Cottier, F.6    Launois, P.7
  • 15
    • 0347297137 scopus 로고    scopus 로고
    • Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens
    • Berberich, C., Ramírez-Pineda, J. R., Hambrecht, C., Alber, G., Skeiky, Y. A., and Moll, H. (2003) Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens. J. Immunol. 170, 3171-3179 (Pubitemid 36302194)
    • (2003) Journal of Immunology , vol.170 , Issue.6 , pp. 3171-3179
    • Berberich, C.1    Ramirez-Pineda, J.R.2    Hambrecht, C.3    Alber, G.4    Skeiky, Y.A.W.5    Moll, H.6
  • 16
    • 0034533054 scopus 로고    scopus 로고
    • Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis
    • DOI 10.1002/1521-4141(2000012)30:12<3498::AID-IMMU3498>3.0.CO;2-6
    • von Stebut, E., Belkaid, Y., Nguyen, B. V., Cushing, M., Sacks, D. L., and Udey, M. C. (2000) Leishmania major-infected murine langerhans celllike dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis. Eur. J. Immunol. 30, 3498-3506 (Pubitemid 32005221)
    • (2000) European Journal of Immunology , vol.30 , Issue.12 , pp. 3498-3506
    • Von Stebut, E.1    Belkaid, Y.2    Nguyen, B.V.3    Cushing, M.4    Sacks, D.L.5    Udey, M.C.6
  • 17
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • DOI 10.1038/ni1112
    • Iwasaki, A., and Medzhitov, R. (2004) Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987-995 (Pubitemid 41057715)
    • (2004) Nature Immunology , vol.5 , Issue.10 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 19
    • 1842536392 scopus 로고    scopus 로고
    • Toll-Like Receptor 4 Contributes to Efficient Control of Infection with the Protozoan Parasite Leishmania major
    • DOI 10.1128/IAI.72.4.1920-1928.2004
    • Kropf, P., Freudenberg, M. A., Modolell, M., Price, H. P., Herath, S., Antoniazi, S., Galanos, C., Smith, D. F., and Müller, I. (2004) Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major. Infect. Immun. 72, 1920-1928 (Pubitemid 38419902)
    • (2004) Infection and Immunity , vol.72 , Issue.4 , pp. 1920-1928
    • Kropf, P.1    Freudenberg, M.A.2    Modolell, M.3    Price, H.P.4    Herath, S.5    Antoniazi, S.6    Galanos, C.7    Smith, D.F.8    Muller, I.9
  • 20
    • 79951815286 scopus 로고    scopus 로고
    • TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like
    • Siednienko, J., Halle, A., Nagpal, K., Golenbock, D. T., and Miggin, S. M. (2010) TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like. Eur. J. Immunol. 40, 3150-3160
    • (2010) Eur. J. Immunol. , vol.40 , pp. 3150-3160
    • Siednienko, J.1    Halle, A.2    Nagpal, K.3    Golenbock, D.T.4    Miggin, S.M.5
  • 21
    • 37549051275 scopus 로고    scopus 로고
    • TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis
    • Liese, J., Schleicher, U., and Bogdan, C. (2007) TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis. Eur. J. Immunol. 37, 3424-3434
    • (2007) Eur. J. Immunol. , vol.37 , pp. 3424-3434
    • Liese, J.1    Schleicher, U.2    Bogdan, C.3
  • 22
    • 63149173273 scopus 로고    scopus 로고
    • TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions
    • Abou Fakher, F. H., Rachinel, N., Klimczak, M., Louis, J., and Doyen, N. (2009) TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions. J. Immunol. 182, 1386-1396
    • (2009) J. Immunol. , vol.182 , pp. 1386-1396
    • Abou Fakher, F.H.1    Rachinel, N.2    Klimczak, M.3    Louis, J.4    Doyen, N.5
  • 25
    • 40749098665 scopus 로고    scopus 로고
    • UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
    • DOI 10.1038/nature06726, PII NATURE06726
    • Kim, Y. M., Brinkmann, M. M., Paquet, M. E., and Ploegh, H. L. (2008) UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 452, 234-238 (Pubitemid 351380247)
    • (2008) Nature , vol.452 , Issue.7184 , pp. 234-238
    • Kim, Y.-M.1    Brinkmann, M.M.2    Paquet, M.-E.3    Ploegh, H.L.4
  • 26
    • 0027302364 scopus 로고
    • Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis
    • Afonso, L. C., and Scott, P. (1993) Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis. Infect. Immun. 61, 2952-2959 (Pubitemid 23182292)
    • (1993) Infection and Immunity , vol.61 , Issue.7 , pp. 2952-2959
    • Afonso, L.C.C.1    Scott, P.2
  • 28
    • 21344465240 scopus 로고    scopus 로고
    • TLR signalling and the function of dendritic cells
    • Hemmi, H., and Akira, S. (2005) TLR signalling and the function of dendritic cells. Chem. Immunol. Allergy 86, 120-135 (Pubitemid 40905001)
    • (2005) Chemical Immunology and Allergy , vol.86 , pp. 120-135
    • Hemmi, H.1    Akira, S.2
  • 29
    • 33845204804 scopus 로고    scopus 로고
    • Protozoan encounters with Toll-like receptor signalling pathways: Implications for host parasitism
    • DOI 10.1038/nri1978, PII NRI1978
    • Gazzinelli, R. T., and Denkers, E. Y. (2006) Protozoan encounters with Toll-like receptor signalling pathways: Implications for host parasitism. Nat. Rev. Immunol. 6, 895-906 (Pubitemid 44851732)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.12 , pp. 895-906
    • Gazzinelli, R.T.1    Denkers, E.Y.2
  • 30
    • 0034682553 scopus 로고    scopus 로고
    • The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge
    • DOI 10.1073/pnas.160197797
    • Stobie, L., Gurunathan, S., Prussin, C., Sacks, D. L., Glaichenhaus, N., Wu, C. Y., and Seder, R. A. (2000) The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge. Proc. Natl. Acad. Sci. U.S.A. 97, 8427-8432 (Pubitemid 30639689)
    • (2000) Proceedings of the National Academy of Sciences of the United States of America , vol.97 , Issue.15 , pp. 8427-8432
    • Stobie, L.1    Gurunathan, S.2    Prussin, C.3    Sacks, D.L.4    Glaichenhaus, N.5    Wu, C.-Y.6    Seder, R.A.7
  • 31
    • 0032521881 scopus 로고    scopus 로고
    • Cutting edge: CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis
    • Zimmermann, S., Egeter, O., Hausmann, S., Lipford, G. B., Röcken, M., Wagner, H., and Heeg, K. (1998) CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J. Immunol. 160, 3627-3630 (Pubitemid 28176060)
    • (1998) Journal of Immunology , vol.160 , Issue.8 , pp. 3627-3630
    • Zimmermann, S.1    Egeter, O.2    Hausmann, S.3    Lipford, G.B.4    Rocken, M.5    Wagner, H.6    Heeg, K.7
  • 32
    • 79952789527 scopus 로고    scopus 로고
    • UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii
    • Pifer, R., Benson, A., Sturge, C. R., and Yarovinsky, F. (2011) UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii. J. Biol. Chem. 286, 3307-3314
    • (2011) J. Biol. Chem. , vol.286 , pp. 3307-3314
    • Pifer, R.1    Benson, A.2    Sturge, C.R.3    Yarovinsky, F.4
  • 33
    • 32944481320 scopus 로고    scopus 로고
    • RNA interference reveals a role for TLR2 and TLR3 in the recognition of Leishmania donovani promastigotes by interferon-γ-primed macrophages
    • DOI 10.1002/eji.200535079
    • Flandin, J. F., Chano, F., and Descoteaux, A. (2006) RNA interference reveals a role for TLR2 and TLR3 in the recognition of Leishmania donovani promastigotes by interferon-γ-primed macrophages. Eur. J. Immunol. 36, 411-420 (Pubitemid 43257464)
    • (2006) European Journal of Immunology , vol.36 , Issue.2 , pp. 411-420
    • Flandin, J.-F.1    Chano, F.2    Descoteaux, A.3
  • 35
    • 0034927975 scopus 로고    scopus 로고
    • Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice
    • DOI 10.1016/S1471-4906(00)01811-1, PII S1471490600018111
    • Kaisho, T., and Akira, S. (2001) Dendritic-cell function in Toll-like receptor-and MyD88-knockout mice. Trends Immunol. 22, 78-83 (Pubitemid 32667525)
    • (2001) Trends in Immunology , vol.22 , Issue.2 , pp. 78-83
    • Kaisho, T.1    Akira, S.2
  • 38
    • 79953268563 scopus 로고    scopus 로고
    • Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo
    • Cockburn, I. A., Tse, S. W., Radtke, A. J., Srinivasan, P., Chen, Y. C., Sinnis, P., and Zavala, F. (2011) Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo. PLoS Pathog. 7, e1001318
    • (2011) PLoS Pathog. , vol.7
    • Cockburn, I.A.1    Tse, S.W.2    Radtke, A.J.3    Srinivasan, P.4    Chen, Y.C.5    Sinnis, P.6    Zavala, F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.