-
1
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
DOI 10.1038/35047123
-
Hemmi, H., O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Matsumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira. 2000. A Toll-like receptor recognizes bacterial DNA. Nature 408: 740-745. (Pubitemid 32015992)
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
2
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg, A. M. 2002. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20: 709-760.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
3
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira, S., S. Uematsu, and O. Takeuchi. 2006. Pathogen recognition and innate immunity. Cell 124: 783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
4
-
-
13944263526
-
Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus
-
DOI 10.1128/JVI.79.5.2847-2858.2005
-
Abe, T., H. Hemmi, H. Miyamoto, K. Moriishi, S. Tamura, H. Takaku, S. Akira, and Y. Matsuura. 2005. Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus. J. Virol. 79: 2847-2858. (Pubitemid 40270563)
-
(2005)
Journal of Virology
, vol.79
, Issue.5
, pp. 2847-2858
-
-
Abe, T.1
Hemmi, H.2
Miyamoto, H.3
Moriishi, K.4
Tamura, S.5
Takaku, H.6
Akira, S.7
Matsuura, Y.8
-
5
-
-
34248386887
-
Structuredependent modulation of α interferon production by porcine circovirus 2 oligodeoxyribonucleotide and CpG DNAs in porcine peripheral blood mononuclear cells
-
Wikstrom, F. H., B. M. Meehan, M. Berg, S. Timmusk, J. Elving, L. Fuxler, M. Magnusson, G. M. Allan, F. McNeilly, and C. Fossum. 2007. Structuredependent modulation of α interferon production by porcine circovirus 2 oligodeoxyribonucleotide and CpG DNAs in porcine peripheral blood mononuclear cells. J. Virol. 81: 4919-4927.
-
(2007)
J. Virol.
, vol.81
, pp. 4919-4927
-
-
Wikstrom, F.H.1
Meehan, B.M.2
Berg, M.3
Timmusk, S.4
Elving, J.5
Fuxler, L.6
Magnusson, M.7
Allan, G.M.8
McNeilly, F.9
Fossum, C.10
-
6
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
DOI 10.1038/ni1028
-
Latz, E., A. Schoenemeyer, A. Visintin, K. A. Fitzgerald, B. G. Monks, C. F. Knetter, E. Lien, N. J. Nilsen, T. Espevik, and D. T. Golenbock. 2004. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat. Immunol. 5: 190-198. (Pubitemid 38208361)
-
(2004)
Nature Immunology
, vol.5
, Issue.2
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
Fitzgerald, K.A.4
Monks, B.G.5
Knetter, C.F.6
Lien, E.7
Nilsen, N.J.8
Espevik, T.9
Golenbock, D.T.10
-
7
-
-
23444434703
-
The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent
-
Drennan, M. B., B. Stijlemans, J. Van den Abbeele, V. J. Quesniaux, M. Barkhuizen, F. Brombacher, P. De Baetselier, B. Ryffel, and S. Magez. 2005. The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent. J. Immunol. 175: 2501-2509.
-
(2005)
J. Immunol.
, vol.175
, pp. 2501-2509
-
-
Drennan, M.B.1
Stijlemans, B.2
Van Den Abbeele, J.3
Quesniaux, V.J.4
Barkhuizen, M.5
Brombacher, F.6
De Baetselier, P.7
Ryffel, B.8
Magez, S.9
-
8
-
-
33748477504
-
Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection
-
Bafica, A., H. C. Santiago, R. Goldszmid, C. Ropert, R. T. Gazzinelli, and A. Sher. 2006. Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection. J. Immunol. 177: 3515-3519. (Pubitemid 44359881)
-
(2006)
Journal of Immunology
, vol.177
, Issue.6
, pp. 3515-3519
-
-
Bafica, A.1
Santiago, H.C.2
Goldszmid, R.3
Ropert, C.4
Gazzinelli, R.T.5
Sher, A.6
-
9
-
-
33846911691
-
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
-
DOI 10.1073/pnas.0608745104
-
Parroche, P., F. N. Lauw, N. Goutagny, E. Latz, B. G. Monks, A. Visintin, K. A. Halmen, M. Lamphier, M. Olivier, D. C. Bartholomeu, et al. 2007. Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc. Natl. Acad. Sci. USA 104: 1919-1924. (Pubitemid 46239879)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.6
, pp. 1919-1924
-
-
Parroche, P.1
Lauw, F.N.2
Goutagny, N.3
Latz, E.4
Monks, B.G.5
Visintin, A.6
Halmen, K.A.7
Lamphier, M.8
Olivier, M.9
Bartholomeu, D.C.10
Gazzinelli, R.T.11
Golenbock, D.T.12
-
10
-
-
33845204804
-
Protozoan encounters with Toll-like receptor signalling pathways: Implications for host parasitism
-
Gazzinelli, R. T., and E. Y. Denkers. 2006. Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism. Nat. Rev. Immunol. 6: 895-906.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 895-906
-
-
Gazzinelli, R.T.1
Denkers, E.Y.2
-
11
-
-
11944272029
-
Innate and acquired immunity in the pathogenesis of Chagas disease
-
DOI 10.1080/08916930410001713115
-
Golgher, D., and R. T. Gazzinelli. 2004. Innate and acquired immunity in the pathogenesis of Chagas disease. Autoimmunity 37: 399-409. (Pubitemid 40100698)
-
(2004)
Autoimmunity
, vol.37
, Issue.5
, pp. 399-409
-
-
Golgher, D.1
Gazzinelli, R.T.2
-
12
-
-
1642525756
-
Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88
-
Campos, M. A., M. Closel, E. P. Valente, J. E. Cardoso, S. Akira, J. I. Alvarez-Leite, C. Ropert, and R. T. Gazzinelli. 2004. Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88. J. Immunol. 172: 1711-1718.
-
(2004)
J. Immunol.
, vol.172
, pp. 1711-1718
-
-
Campos, M.A.1
Closel, M.2
Valente, E.P.3
Cardoso, J.E.4
Akira, S.5
Alvarez-Leite, J.I.6
Ropert, C.7
Gazzinelli, R.T.8
-
13
-
-
0035399862
-
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
-
Campos, M. A., I. C. Almeida, O. Takeuchi, S. Akira, E. P. Valente, D. O. Procopio, L. R. Travassos, J. A. Smith, D. T. Golenbock, and R. T. Gazzinelli. 2001. Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. J. Immunol. 167: 416-423.
-
(2001)
J. Immunol.
, vol.167
, pp. 416-423
-
-
Campos, M.A.1
Almeida, I.C.2
Takeuchi, O.3
Akira, S.4
Valente, E.P.5
Procopio, D.O.6
Travassos, L.R.7
Smith, J.A.8
Golenbock, D.T.9
Gazzinelli, R.T.10
-
14
-
-
6344241296
-
Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi
-
Oliveira, A. C., J. R. Peixoto, L. B. de Arruda, M. A. Campos, R. T. Gazzinelli, D. T. Golenbock, S. Akira, J. O. Previato, L. Mendonca-Previato, A. Nobrega, and M. Bellio. 2004. Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi. J. Immunol. 173: 5688-5696.
-
(2004)
J. Immunol.
, vol.173
, pp. 5688-5696
-
-
Oliveira, A.C.1
Peixoto, J.R.2
De Arruda, L.B.3
Campos, M.A.4
Gazzinelli, R.T.5
Golenbock, D.T.6
Akira, S.7
Previato, J.O.8
Mendonca-Previato, L.9
Nobrega, A.10
Bellio, M.11
-
15
-
-
0035082873
-
DNA from protozoan parasites Babesia bovis, Trypanosoma cruzi, and T. brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor α, and nitric oxide
-
Shoda, L. K., K. A. Kegerreis, C. E. Suarez, I. Roditi, R. S. Corral, G. M. Bertot, J. Norimine, and W. C. Brown. 2001. DNA from protozoan parasites Babesia bovis, Trypanosoma cruzi, and T. brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor α, and nitric oxide. Infect. Immun. 69: 2162-2171.
-
(2001)
Infect. Immun.
, vol.69
, pp. 2162-2171
-
-
Shoda, L.K.1
Kegerreis, K.A.2
Suarez, C.E.3
Roditi, I.4
Corral, R.S.5
Bertot, G.M.6
Norimine, J.7
Brown, W.C.8
-
16
-
-
33746645926
-
Signal transduction, gene transcription, and cytokine production triggered in macrophages by exposure to trypanosome DNA
-
Harris, T. H., N. M. Cooney, J. M. Mansfield, and D. M. Paulnock. 2006. Signal transduction, gene transcription, and cytokine production triggered in macrophages by exposure to trypanosome DNA. Infect. Immun. 74: 4530-4537.
-
(2006)
Infect. Immun.
, vol.74
, pp. 4530-4537
-
-
Harris, T.H.1
Cooney, N.M.2
Mansfield, J.M.3
Paulnock, D.M.4
-
17
-
-
0034662239
-
Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2
-
Hirschfeld, M., Y. Ma, J. H. Weis, S. N. Vogel, and J. J. Weis. 2000. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J. Immunol. 165: 618-622. (Pubitemid 30484724)
-
(2000)
Journal of Immunology
, vol.165
, Issue.2
, pp. 618-622
-
-
Hirschfeld, M.1
Ma, Y.2
Weis, J.H.3
Vogel, S.N.4
Weis, J.J.5
-
18
-
-
22244453726
-
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
-
El-Sayed, N. M., P. J. Myler, D. C. Bartholomeu, D. Nilsson, G. Aggarwal, A. N. Tran, E. Ghedin, E. A. Worthey, A. L. Delcher, G. Blandin, et al. 2005. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science 309: 409-415.
-
(2005)
Science
, vol.309
, pp. 409-415
-
-
El-Sayed, N.M.1
Myler, P.J.2
Bartholomeu, D.C.3
Nilsson, D.4
Aggarwal, G.5
Tran, A.N.6
Ghedin, E.7
Worthey, E.A.8
Delcher, A.L.9
Blandin, G.10
-
19
-
-
78651145402
-
Growth and differentiation in Trypanosoma cruzi: I. Origin of metacyclic trypanosomes in liquid media
-
Camargo, E. P. 1964. Growth and differentiation in Trypanosoma cruzi: I. Origin of metacyclic trypanosomes in liquid media. Rev. Inst. Med. Trop. Sao Paulo 12: 93-100.
-
(1964)
Rev. Inst. Med. Trop. Sao Paulo
, vol.12
, pp. 93-100
-
-
Camargo, E.P.1
-
20
-
-
0032981150
-
Expression of a marker for intracellular Trypanosoma cruzi amastigotes in extracellular spheromastigotes
-
Teixeira, S. M., K. Otsu, K. L. Hill, L. V. Kirchhoff, and J. E. Donelson. 1999. Expression of a marker for intracellular Trypanosoma cruzi amastigotes in extracellular spheromastigotes. Mol. Biochem. Parasitol. 98: 265-270.
-
(1999)
Mol. Biochem. Parasitol.
, vol.98
, pp. 265-270
-
-
Teixeira, S.M.1
Otsu, K.2
Hill, K.L.3
Kirchhoff, L.V.4
Donelson, J.E.5
-
21
-
-
0442329282
-
Expression of exogenous genes in Trypanosoma cruzi: Improving vectors and electroporation protocols
-
DaRocha, W. D., R. A. Silva, D. C. Bartholomeu, S. F. Pires, J. M. Freitas, A. M. Macedo, M. P. Vazquez, M. J. Levin, and S. M. Teixeira. 2004. Expression of exogenous genes in Trypanosoma cruzi: improving vectors and electroporation protocols. Parasitol. Res. 92: 113-120.
-
(2004)
Parasitol. Res.
, vol.92
, pp. 113-120
-
-
Darocha, W.D.1
Silva, R.A.2
Bartholomeu, D.C.3
Pires, S.F.4
Freitas, J.M.5
Macedo, A.M.6
Vazquez, M.P.7
Levin, M.J.8
Teixeira, S.M.9
-
22
-
-
38949217383
-
Cell culture and animal infection with distinct Trypanosoma cruzi strains expressing red and green fluorescent proteins
-
Pires, S. F., W. D. DaRocha, J. M. Freitas, L. A. Oliveira, G. T. Kitten, C. R. Machado, S. D. Pena, A. E. Chiari, A. M. Macedo, and S. M. Teixeira. 2008. Cell culture and animal infection with distinct Trypanosoma cruzi strains expressing red and green fluorescent proteins. Int. J. Parasitol. 38: 289-297.
-
(2008)
Int. J. Parasitol.
, vol.38
, pp. 289-297
-
-
Pires, S.F.1
Darocha, W.D.2
Freitas, J.M.3
Oliveira, L.A.4
Kitten, G.T.5
Machado, C.R.6
Pena, S.D.7
Chiari, A.E.8
Macedo, A.M.9
Teixeira, S.M.10
-
23
-
-
0031570514
-
Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages
-
Camargo, M. M., I. C. Almeida, M. E. Pereira, M. A. Ferguson, L. R. Travassos, and R. T. Gazzinelli. 1997. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages. J. Immunol. 158: 5890-5901.
-
(1997)
J. Immunol.
, vol.158
, pp. 5890-5901
-
-
Camargo, M.M.1
Almeida, I.C.2
Pereira, M.E.3
Ferguson, M.A.4
Travassos, L.R.5
Gazzinelli, R.T.6
-
24
-
-
0031570843
-
Interleukin-10 Prevents Dendritic Cell Accumulation and Vaccination with Granulocyte-Macrophage Colony-Stimulating Factor Gene-Modified Tumor Cells
-
Qin, Z., G. Noffz, M. Mohaupt, and T. Blankenstein. 1997. Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells. J. Immunol. 159: 770-776. (Pubitemid 127484228)
-
(1997)
Journal of Immunology
, vol.159
, Issue.2
, pp. 770-776
-
-
Qin, Z.1
Noffz, G.2
Mohaupt, M.3
Blankenstein, T.4
-
25
-
-
34250698370
-
Ligand-induced conformational changes allosterically activate Toll-like receptor 9
-
DOI 10.1038/ni1479, PII NI1479
-
Latz, E., A. Verma, A. Visintin, M. Gong, C. M. Sirois, D. C. Klein, B. G. Monks, C. J. McKnight, M. S. Lamphier, W. P. Duprex, et al. 2007. Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nat. Immunol. 8: 772-779. (Pubitemid 46965353)
-
(2007)
Nature Immunology
, vol.8
, Issue.7
, pp. 772-779
-
-
Latz, E.1
Verma, A.2
Visintin, A.3
Gong, M.4
Sirois, C.M.5
Klein, D.C.G.6
Monks, B.G.7
McKnight, J.C.8
Lamphier, M.S.9
Duprex, P.W.10
Espevik, T.11
Golenbock, D.T.12
-
26
-
-
0034142182
-
Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
-
Hartmann, G., R. D. Weeratna, Z. K. Ballas, P. Payette, S. Blackwell, I. Suparto, W. L. Rasmussen, M. Waldschmidt, D. Sajuthi, R. H. Purcell, et al. 2000. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J. Immunol. 164: 1617-1624. (Pubitemid 30067282)
-
(2000)
Journal of Immunology
, vol.164
, Issue.3
, pp. 1617-1624
-
-
Hartmann, G.1
Weeratna, R.D.2
Ballas, Z.K.3
Payette, P.4
Blackwell, S.5
Suparto, I.6
Rasmussen, W.L.7
Waldschmidt, M.8
Sajuthi, D.9
Purcell, R.H.10
Davis, H.L.11
Krieg, A.M.12
-
27
-
-
33745807284
-
CpG motifs to modulate innate and adaptive immune responses
-
DOI 10.1080/08830180600743115, PII K480267G31604365
-
Vollmer, J. 2006. CpG motifs to modulate innate and adaptive immune responses. Int. Rev. Immunol. 25: 125-134. (Pubitemid 44034577)
-
(2006)
International Reviews of Immunology
, vol.25
, Issue.3-4
, pp. 125-134
-
-
Vollmer, J.1
-
28
-
-
33845871431
-
Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: Structural studies and immunomodulatory activity in primates
-
DOI 10.1093/nar/gkl867
-
Puig, M., A. Grajkowski, M. Boczkowska, C. Ausin, S. L. Beaucage, and D. Verthelyi. 2006. Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: structural studies and immunomodulatory activity in primates. Nucleic Acids Res. 34: 6488-6495. (Pubitemid 46017945)
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.22
, pp. 6488-6495
-
-
Puig, M.1
Grajkowski, A.2
Boczkowska, M.3
Ausin, C.4
Beaucage, S.L.5
Verthelyi, D.6
-
29
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
DOI 10.1038/35099560
-
Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413: 732-738. (Pubitemid 33009951)
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
30
-
-
1542317550
-
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
-
DOI 10.1126/science.1093616
-
Diebold, S. S., T. Kaisho, H. Hemmi, S. Akira, and E. S. C. Reis. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303: 1529-1531. (Pubitemid 38314425)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis E Sousa, C.5
-
31
-
-
1542317578
-
Species-Specific Recognition of Single-Stranded RNA via Till-like Receptor 7 and 8
-
DOI 10.1126/science.1093620
-
Heil, F., H. Hemmi, H. Hochrein, F. Ampenberger, C. Kirschning, S. Akira, G. Lipford, H. Wagner, and S. Bauer. 2004. Species-specific recognition of single- stranded RNA via toll-like receptor 7 and 8. Science 303: 1526-1529. (Pubitemid 38314424)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
32
-
-
31844433093
-
Activation of toll-like receptor 9 by DNA from different bacterial species
-
DOI 10.1128/IAI.74.2.940-946.2006
-
Dalpke, A., J. Frank, M. Peter, and K. Heeg. 2006. Activation of Toll-like receptor 9 by DNA from different bacterial species. Infect. Immun. 74: 940-946. (Pubitemid 43185528)
-
(2006)
Infection and Immunity
, vol.74
, Issue.2
, pp. 940-946
-
-
Dalpke, A.1
Frank, J.2
Peter, M.3
Heeg, K.4
-
33
-
-
30544451181
-
The VIPER elements of trypanosomes constitute a novel group of tyrosine recombinase-encoding retrotransposons
-
Lorenzi, H. A., G. Robledo, and M. J. Levin. 2006. The VIPER elements of trypanosomes constitute a novel group of tyrosine recombinase-encoding retrotransposons. Mol. Biochem. Parasitol. 145: 184-194.
-
(2006)
Mol. Biochem. Parasitol.
, vol.145
, pp. 184-194
-
-
Lorenzi, H.A.1
Robledo, G.2
Levin, M.J.3
-
34
-
-
0025006614
-
Origin and evolution of retroelements based upon their reverse transcriptase sequences
-
Xiong, Y., and T. H. Eickbush. 1990. Origin and evolution of retroelements based upon their reverse transcriptase sequences. EMBO J. 9: 3353-3362. (Pubitemid 20282550)
-
(1990)
EMBO Journal
, vol.9
, Issue.10
, pp. 3353-3362
-
-
Xiong, Y.1
Eickbush, T.H.2
-
35
-
-
0034933019
-
Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells
-
DOI 10.1002/1521-4141(200107)31:7<2154::AID-IMMU2154>3.0.CO;2-U
-
Krug, A., S. Rothenfusser, V. Hornung, B. Jahrsdorfer, S. Blackwell, Z. K. Ballas, S. Endres, A. M. Krieg, and G. Hartmann. 2001. Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells. Eur. J. Immunol. 31: 2154-2163. (Pubitemid 32640732)
-
(2001)
European Journal of Immunology
, vol.31
, Issue.7
, pp. 2154-2163
-
-
Krug, A.1
Rothenfusser, S.2
Hornung, V.3
Jahrsdrfer, B.4
Blackwell, S.5
Ballas, Z.K.6
Endres, S.7
Krieg, A.M.8
Hartmann, G.9
-
36
-
-
0035149345
-
Pivotal role of interleukin-12 and interferon-γ axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection
-
Michailowsky, V., N. M. Silva, C. D. Rocha, L. Q. Vieira, J. Lannes-Vieira, and R. T. Gazzinelli. 2001. Pivotal role of interleukin-12 and interferon-γ axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection. Am. J. Pathol. 159: 1723-1733. (Pubitemid 33062515)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.5
, pp. 1723-1733
-
-
Michailowsky, V.1
Silva, N.M.2
Rocha, C.D.3
Vieira, L.Q.4
Lannes-Vieira, J.5
Gazzinelli, R.T.6
-
37
-
-
0022572066
-
Persistence of polyclonal B cell activation with undetectable parasitemia in late stages of experimental Chagas' disease
-
d'Imperio Lima, M. R., H. Eisen, P. Minoprio, M. Joskowicz, and A. Coutinho. 1986. Persistence of polyclonal B cell activation with undetectable parasitemia in late stages of experimental Chagas' disease. J. Immunol. 137: 353-356.
-
(1986)
J. Immunol.
, vol.137
, pp. 353-356
-
-
Lima, D.1
Eisen, M.R.H.2
Minoprio, P.3
Joskowicz, M.4
Coutinho, A.5
-
38
-
-
0033835159
-
A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase
-
DOI 10.1038/78651
-
Reina-San-Martin, B., W. Degrave, C. Rougeot, A. Cosson, N. Chamond, A. Cordeiro-Da-Silva, M. Arala-Chaves, A. Coutinho, and P. Minoprio. 2000. A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase. Nat. Med. 6: 890-897. (Pubitemid 30644747)
-
(2000)
Nature Medicine
, vol.6
, Issue.8
, pp. 890-897
-
-
Reina-San-Martin, B.1
Degrave, W.2
Rougeot, C.3
Cosson, A.4
Chamond, N.5
Cordeiro-da-Silva, A.6
Arala-Chaves, M.7
Coutinho, A.8
Minoprio, P.9
-
39
-
-
0037016762
-
Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription
-
de Avalos, S. V., I. J. Blader, M. Fisher, J. C. Boothroyd, and B. A. Burleigh. 2002. Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription. J. Biol. Chem. 277: 639-644.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 639-644
-
-
De Avalos, S.V.1
Blader, I.J.2
Fisher, M.3
Boothroyd, J.C.4
Burleigh, B.A.5
-
40
-
-
33747756473
-
Type I IFNs stimulate nitric oxide production and resistance to Trypanosoma cruzi infection
-
Costa, V. M., K. C. Torres, R. Z. Mendonca, I. Gresser, K. J. Gollob, and I. A. Abrahamsohn. 2006. Type I IFNs stimulate nitric oxide production and resistance to Trypanosoma cruzi infection. J. Immunol. 177: 3193-3200.
-
(2006)
J. Immunol.
, vol.177
, pp. 3193-3200
-
-
Costa, V.M.1
Torres, K.C.2
Mendonca, R.Z.3
Gresser, I.4
Gollob, K.J.5
Abrahamsohn, I.A.6
-
41
-
-
33750833949
-
TLR-dependent induction of IFN-β mediates host defense against Trypanosoma cruzi
-
Koga, R., S. Hamano, H. Kuwata, K. Atarashi, M. Ogawa, H. Hisaeda, M. Yamamoto, S. Akira, K. Himeno, M. Matsumoto, and K. Takeda. 2006. TLRdependent induction of IFN-βmediates host defense against Trypanosoma cruzi. J. Immunol. 177: 7059-7066. (Pubitemid 44715073)
-
(2006)
Journal of Immunology
, vol.177
, Issue.10
, pp. 7059-7066
-
-
Koga, R.1
Hamano, S.2
Kuwata, H.3
Atarashi, K.4
Ogawa, M.5
Hisaeda, H.6
Yamamoto, M.7
Akira, S.8
Himeno, K.9
Matsumoto, M.10
Takeda, K.11
-
42
-
-
17844380477
-
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
-
DOI 10.1038/nature03547
-
Honda, K., Y. Ohba, H. Yanai, H. Negishi, T. Mizutani, A. Takaoka, C. Taya, and T. Taniguchi. 2005. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 434: 1035-1040. (Pubitemid 40586053)
-
(2005)
Nature
, vol.434
, Issue.7036
, pp. 1035-1040
-
-
Honda, K.1
Ohba, Y.2
Yanai, H.3
Hegishi, H.4
Mizutani, T.5
Takaoka, A.6
Taya, C.7
Taniguchi, T.8
-
43
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
DOI 10.1038/nature06013, PII NATURE06013
-
Takaoka, A., Z. Wang, M. K. Choi, H. Yanai, H. Negishi, T. Ban, Y. Lu, M. Miyagishi, T. Kodama, K. Honda, et al. 2007. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448: 501-505. (Pubitemid 47123520)
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
Lu, Y.7
Miyagishi, M.8
Kodama, T.9
Honda, K.10
Ohba, Y.11
Taniguchi, T.12
-
44
-
-
0027049531
-
Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells
-
DOI 10.1016/S0092-8674(05)80061-3
-
Tardieux, I., P. Webster, J. Ravesloot, W. Boron, J. A. Lunn, J. E. Heuser, and N. W. Andrews. 1992. Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells. Cell 71: 1117-1130. (Pubitemid 23016547)
-
(1992)
Cell
, vol.71
, Issue.7
, pp. 1117-1130
-
-
Tardieux, I.1
Webster, P.2
Ravesloot, J.3
Boron, W.4
Lunn, J.A.5
Heuser, J.E.6
Andrews, N.W.7
-
45
-
-
0042829418
-
Novel PI 3-kinase-dependent mechanisms of trypanosome invasion and vacuole maturation
-
Woolsey, A. M., L. Sunwoo, C. A. Petersen, S. M. Brachmann, L. C. Cantley, and B. A. Burleigh. 2003. Novel PI 3-kinase-dependent mechanisms of trypanosome invasion and vacuole maturation. J. Cell Sci. 116: 3611-3622.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 3611-3622
-
-
Woolsey, A.M.1
Sunwoo, L.2
Petersen, C.A.3
Brachmann, S.M.4
Cantley, L.C.5
Burleigh, B.A.6
-
46
-
-
8644238313
-
Lysosomal fusion is essential for the retention of Trypanosoma cruzi inside host cells
-
Andrade, L. O., and N. W. Andrews. 2004. Lysosomal fusion is essential for the retention of Trypanosoma cruzi inside host cells. J. Exp. Med. 200: 1135-1143.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1135-1143
-
-
Andrade, L.O.1
Andrews, N.W.2
-
47
-
-
0037015614
-
Genome sequence of the human malaria parasite Plasmodium falciparum
-
Gardner, M. J., N. Hall, E. Fung, O. White, M. Berriman, R. W. Hyman, J. M. Carlton, A. Pain, K. E. Nelson, S. Bowman, et al. 2002. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419: 498-511.
-
(2002)
Nature
, vol.419
, pp. 498-511
-
-
Gardner, M.J.1
Hall, N.2
Fung, E.3
White, O.4
Berriman, M.5
Hyman, R.W.6
Carlton, J.M.7
Pain, A.8
Nelson, K.E.9
Bowman, S.10
-
48
-
-
22244472295
-
Comparative genomics of trypanosomatid parasitic protozoa
-
El-Sayed, N. M., P. J. Myler, G. Blandin, M. Berriman, J. Crabtree, G. Aggarwal, E. Caler, H. Renauld, E. A. Worthey, C. Hertz-Fowler, et al. 2005. Comparative genomics of trypanosomatid parasitic protozoa. Science 309: 404-409.
-
(2005)
Science
, vol.309
, pp. 404-409
-
-
El-Sayed, N.M.1
Myler, P.J.2
Blandin, G.3
Berriman, M.4
Crabtree, J.5
Aggarwal, G.6
Caler, E.7
Renauld, H.8
Worthey, E.A.9
Hertz-Fowler, C.10
-
49
-
-
0034058369
-
The short interspersed repetitive element of Trypanosoma cruzi, SIRE, is part of VIPER, an unusual retroelement related to long terminal repeat retrotransposons
-
DOI 10.1073/pnas.050578397
-
Vazquez, M., C. Ben-Dov, H. Lorenzi, T. Moore, A. Schijman, and M. J. Levin. 2000. The short interspersed repetitive element of Trypanosoma cruzi, SIRE, is part of VIPER, an unusual retroelement related to long terminal repeat retrotransposons. Proc. Natl. Acad. Sci. USA 97: 2128-2133. (Pubitemid 30134033)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.5
, pp. 2128-2133
-
-
Vazquez, M.1
Ben-Dov, C.2
Lorenzi, H.3
Moore, T.4
Schijman, A.5
Levin, M.J.6
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