B7H1/CD80 interaction augments PD-1-dependent T Cell apoptosis and ameliorates graft-versus-host disease

Journal of Immunology

Volumn 194, Issue 2, 2015, Pages 560-574

  Deng, Ruishu ^a   Cassady, Kaniel ^a,b   Li, Xiaofan ^a,c   Yao, Sheng ^d   Zhang, Mingfeng ^a   Racine, Jeremy ^a,b   Lin, Jeffrey ^a   Chen, Lieping ^c   Zeng, Defu ^a,b  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b Irell and Manella Graduate School of Biological Sciences   (United States)

^c FUJIAN MEDICAL UNIVERSITY   (China)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; INTERLEUKIN 10; INTERLEUKIN 2; MONOCLONAL ANTIBODY; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 1 MONOCLONAL ANTIBODY; PROGRAMMED DEATH LIGAND 1 IMMUNOGLOBULIN FC DOMAIN FUSION PROTEIN; UNCLASSIFIED DRUG; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 RECEPTOR;

ALLOIMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLONAL ANERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; GRAFT VERSUS HOST REACTION; HYDRODYNAMICS BASED TRANSFECTION; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; WILD TYPE; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GRAFT VS HOST DISEASE; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; ANTIGENS, CD274; ANTIGENS, CD80; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GRAFT VS HOST DISEASE; INTERLEUKIN-2; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PROGRAMMED CELL DEATH 1 RECEPTOR; RECOMBINANT FUSION PROTEINS;

EID: 84920398319     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402157     Document Type: Article

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