Early post-stressor intervention with minocycline, a second-generation tetracycline, attenuates post-traumatic stress response in an animal model of PTSD

European Neuropsychopharmacology

Volumn 25, Issue 1, 2015, Pages 124-132

  Levkovitz, Yechiel ^a,d   Fenchel, Daphna ^a,d   Kaplan, Zeev ^b   Zohar, Joseph ^c,d   Cohen, Hagit ^b  

^a BEER YAAKOV MENTAL HEALTH CENTER   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c MINISTRY OF HEALTH   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Animal model; Interleukin 1 (IL 1); Interleukin 6 (IL 6); Minocycline; Post traumatic stress disorder; Tumor necrosis factor (TNF )

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 6; MINOCYCLINE; TUMOR NECROSIS FACTOR ALPHA; ANTIDEPRESSANT AGENT; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELEVATED PLUS MAZE TEST; FREEZING; FRONTAL CORTEX; HIPPOCAMPUS; HYPOTHALAMUS; INTERVENTION STUDY; MALE; MENTAL STRESS; NEUROPHARMACOLOGY; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; POSTTRAUMATIC STRESS DISORDER; PSYCHOPHARMACOLOGY; RAT; SINGLE DRUG DOSE; STARTLE REFLEX; ANALYSIS OF VARIANCE; ANIMAL; ASSOCIATION; AUDITORY STIMULATION; BRAIN; CATALEPSY; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; DRUG THERAPY; ENZYME LINKED IMMUNOSORBENT ASSAY; ETIOLOGY; MAZE TEST; METABOLISM; SPRAGUE DAWLEY RAT; TIME;

ACOUSTIC STIMULATION; ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN; CUES; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FREEZING REACTION, CATALEPTIC; MALE; MAZE LEARNING; MINOCYCLINE; RATS; RATS, SPRAGUE-DAWLEY; REFLEX, STARTLE; STRESS DISORDERS, POST-TRAUMATIC; STRESS, PSYCHOLOGICAL; TIME FACTORS;

EID: 84920388943     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2014.11.012     Document Type: Article

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