Broad spectrum of cytokine abnormalities in Panic disorder and Posttraumatic stress disorder

Depression and Anxiety

Volumn 26, Issue 5, 2009, Pages 447-455

  Hoge, E A ^a   Brandstetter, K ^b   Moshier, S ^a   Pollack, M H ^a   Wong, K K ^b   Simon, N M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Chemokine; Cytokine; Inflammation; Panic; Posttrau matic stress disorder; Proinflammatory; PTSD; Stress

Indexed keywords

ALPHA INTERFERON; CHEMOKINE; EOTAXIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADULT; ANALYTIC METHOD; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ASSOCIATION; FEMALE; FISHER EXACT TEST; HUMAN; HYPOTHESIS; INFLAMMATION; MALE; MEDICAL TECHNOLOGY; PANIC; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ASSAY; SYMPTOMATOLOGY;

ADULT; AGORAPHOBIA; CHEMOKINES; CYTOKINES; FEMALE; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; PANIC DISORDER; REFERENCE VALUES; STRESS DISORDERS, POST-TRAUMATIC;

EID: 66249129401     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20564     Document Type: Article

References (61)

1. Simon NM, McNamara K, Chow CW et al. A detailed examination of cytokine abnormalities in major depressive disorder. Eur Neuropsychopharmacol 2008;18:230-233.
2. Koo JW, Duman RS. IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc Natl Acad Sci USA 2008;105:751-756.
3. Maes M, Meltzer HY, Bosmans E et al. Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. J Affect Disord 1995;34:301-309.
4. Raison CL, Capuron L, Miller AH. Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol 2006;27:24-31.
5. Hayley S, Poulter MO, Merali Z, Anisman H. The pathogenesis of clinical depression: stressor- and cytokine-induced alterations of neuroplasticity. Neuroscience 2005;135:659-678.
6. Schiepers OJ, Wichers MC, Maes M. Cytokines and major depression. Prog Neuropsychopharmacol Biol Psychiatry 2005;29:201-217.
7. Maes M. Evidence for an immune response in major depression: a review and hypothesis. Prog Neuropsychopharmacol Biol Psychiatry 1995;19:11-38.
8. Dantzer R, Kelley KW. Twenty years of research on cytokine- induced sickness behavior. Brain Behav Immun 2007;21: 153-160.
9. Irwin MR, Miller AH. Depressive disorders and immunity: 20 years of progress and discovery. Brain Behav Immun 2007;21: 374-383.
10. Vaccarino V, Johnson BD, Sheps DS et al. Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE study. J Am Coll Cardiol 2007;50:2044-2050.
11. Parissis JT, Adamopoulos S, Rigas A et al. Comparison of circulating proinflammatory cytokines and soluble apoptosis mediators in patients with chronic heart failure with versus without symptoms of depression. Am J Cardiol 2004;94: 1326-1328.
12. Glaser R, Kiecolt-Glaser JK. Stress-induced immune dysfunc- tion: implications for health. Nat Rev Immunol 2005;5: 243-251.
13. Kiecolt-Glaser JK, McGuire L, Robles TF, Glaser R. Psycho- neuroimmunology and psychosomatic medicine: back to the future. Psychosom Med 2002;64:15-28.
14. Kiecolt-Glaser JK, Preacher KJ, MacCallum RC et al. Chronic stress and age-related increases in the proinflammatory cytokine IL-6. Proc Natl Acad Sci USA 2003;100:9090-9095.
15. von Kanel R, Dimsdale JE, Mills PJ et al. Effect of Alzheimer caregiving stress and age on frailty markers interleukin-6, C- reactive protein, and D-dimer. J Gerontol A Biol Sci Med Sci 2006;61:963-969.
16. Lutgendorf SK, Garand L, Buckwalter KC et al. Life stress, mood disturbance, and elevated interleukin-6 in healthy older women. J Gerontol A Biol Sci Med Sci 1999;54:M434-M439.
17. Gemes K, Ahnve S, Janszky I. Inflammation a possible link between economical stress and coronary heart disease. Eur J Epidemiol 2008;23:95-103.
18. Maes M, Song C, Lin A et al. The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine 1998;10:313-318.
19. Song C, Kenis G, van Gastel A et al. Influence of psychological stress on immune-inflammatory variables in normal humans. Part II. Altered serum concentrations of natural anti-inflamma- tory agents and soluble membrane antigens of monocytes and T lymphocytes. Psychiatry Res 1999;85:293-303.
20. Weik U, Herforth A, Kolb-Bachofen V, Deinzer R. Acute stress induces proinflammatory signaling at chronic inflammation sites. Psychosom Med 2008;70:906-912.
21. Brydon L, O'Donnell K, Wright CE et al. Circulating leptin and stress-induced cardiovascular activity in humans. Obesity (Silver Spring) 2008;16:2642-2647.
22. Deinzer R, Granrath N, Stuhl H et al. Acute stress effects on local Il-1beta responses to pathogens in a human in vivo model. Brain Behav Immun 2004;18:458-467.
23. Wirtz PH, Ehlert U, Emini L, Suter T. Higher body mass index (BMI) is associated with reduced glucocorticoid inhibition of inflammatory cytokine production following acute psychosocial stress in men. Psychoneuroendocrinology 2008;33:1102-1110.
24. Edwards KM, Burns VE, Ring C, Carroll D. Sex differences in the interleukin-6 response to acute psychological stress. Biol Psychol 2006;71:236-239.
25. Mastrolonardo M, Alicino D, Zefferino R et al. Effect of psychological stress on salivary interleukin-1beta in psoriasis. Arch Med Res 2007;38:206-211.
26. Brydon L, Edwards S, Mohamed-Ali V, Steptoe A. Socio- economic status and stress-induced increases in interleukin-6. Brain Behav Immun 2004;18:281-290.
27. Woods AB, Page GG, O'Campo P et al. The mediation effect of posttraumatic stress disorder symptoms on the relationship of intimate partner violence and IFN-gamma levels. Am J Com- munity Psychol 2005;36:159-175.
28. Tucker P, Ruwe WD, Masters B et al. Neuroimmune and cortisol changes in selective serotonin reuptake inhibitor and placebo treatment of chronic posttraumatic stress disorder. Biol Psychia- try 2004;56:121-128.
29. Song Y, Zhou D, Guan Z, Wang X. Disturbance of serum interleukin-2 and interleukin-8 levels in posttraumatic and non- posttraumatic stress disorder earthquake survivors in northern China. Neuroimmunomodulation 2007;14:248-254.
30. von Kanel R, Hepp U, Kraemer B et al. Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder. J Psychiatr Res 2007;41:744-752.
31. Spivak B, Shohat B, Mester R et al. Elevated levels of serum interleukin-1 beta in combat-related posttraumatic stress dis- order. Biol Psychiatry 1997;42:345-348.
32. Maes M, Lin AH, Delmeire L et al. Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events. Biol Psychiatry 1999;45:833-839.
33. van Duinen MA, Schruers KR, Kenis GR et al. Effects of experimental panic on neuroimmunological functioning. J Psychosom Res 2008;64:305-310.
34. Koh KB, Lee Y. Reduced anxiety level by therapeutic interven- tions and cell-mediated immunity in panic disorder patients. Psychother Psychosom 2004;73:286-292.
35. First MS, Gibbon RL, Williams MJBW. Structured Clinical Interview for Axis I DSM-IV Disorders-Patient version (SCID- 1/P version 2.0). New York: New York State Psychiatric Institute Biometrics Research Department; 1994.
36. Shear MK, Brown TA, Barlow DH et al. Multicenter collabora- tive panic disorder severity scale. Am J Psychiatry 1997;154: 1571-1575.
37. Connor KM, Davidson JR. SPRINT: a brief global assessment of post-traumatic stress disorder. Int Clin Psychopharmacol 2001;16:279-284.
38. Kawamura N, Kim Y, Asukai N. Suppression of cellular immunity in men with a past history of posttraumatic stress disorder. Am J Psychiatry 2001;158:484-486.
39. Baker DG, Ekhator NN, Kasckow JW et al. Plasma and cerebrospinal fluid interleukin-6 concentrations in posttraumatic stress disorder. Neuroimmunomodulation 2001;9:209-217.
40. Opal SM, DePalo VA. Anti-inflammatory cytokines. Chest 2000;117:1162-1172.
41. Rapaport MH, Stein MB. Serum interleukin-2 and soluble interleukin-2 receptor levels in generalized social phobia. Anxiety 1994;1:50-53.
42. Weizman R, Laor N, Wiener Z et al. Cytokine production in panic disorder patients. Clin Neuropharmacol 1999;22: 107-109.
43. Brambilla F, Bellodi L, Perna G et al. Plasma interleukin-1 beta concentrations in panic disorder. Psychiatry Res 1994;54: 135-142.
44. van Duinen H, Post M, Vaartjes K et al. MR compatible strain gauge based force transducer. J Neurosci Methods 2007;164: 247-254.
45. van Duinen MA, Schruers KRJ, Griez EJL, Maes M. Neuroim- munological parameters in panic disorder. Acta Neuropsychia- trica 2004;16:94-100.
46. Calcagni E, Elenkov I. Stress system activity, innate and T helper cytokines, and susceptibility to immune-related diseases. Ann N Y Acad Sci 2006;1069:62-76.
47. Charo IF, Ransohoff RM. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 2006;354: 610-621.
48. Kenis G, Maes M. Effects of antidepressants on the production of cytokines. Int J Neuropsychopharmacol 2002;5:401-412.
49. Creely SJ, McTernan PG, Kusminski CM et al. Lipopolysacchar- ide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am J Physiol Endocrinol Metab 2007;292:E740-E747.
50. Hotamisligil GS, Arner P, Caro JF et al. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995;95:2409-2415.
51. Vgontzas AN, Bixler EO, Lin HM et al. IL-6 and its circadian secretion in humans. Neuroimmunomodulation 2005;12: 131-140.
52. Haus E, Smolensky MH. Biologic rhythms in the immune system. Chronobiol Int 1999;16:581-622.
53. Hermann C, von Aulock S, Dehus O et al. Endogenous cortisol determines the circadian rhythm of lipopolysaccharide-but not lipoteichoic acid-inducible cytokine release. Eur J Immunol 2006;36:371-379.
54. Rohleder N, Schommer NC, Hellhammer DH et al. Sex differences in glucocorticoid sensitivity of proinflammatory cytokine production after psychosocial stress. Psychosom Med 2001;63:966-972.
55. Brydon L, Edwards S, Jia H et al. Psychological stress activates interleukin-1beta gene expression in human mononuclear cells. Brain Behav Immun 2005;19:540-546.
56. Pace TW, Mletzko TC, Alagbe O et al. Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress. Am J Psychiatry 2006;163: 1630-1633.
57. Smoller JW, Pollack MH, Wassertheil-Smoller S et al. Panic attacks and risk of incident cardiovascular events among postmenopausal women in the Women's Health Initiative Observational Study. Arch Gen Psychiatry 2007;64:1153-1160.
58. Walters K, Rait G, Petersen I et al. Panic disorder and risk of new onset coronary heart disease, acute myocardial infarction, and cardiac mortality: cohort study using the general practice research database. Eur Heart J 2008;29:2981-2988.
59. Boscarino JA. Posttraumatic stress disorder and mortality among U. S. Army veterans 30 years after military service. Ann Epidemiol 2006;16:248-256.
60. McEwen BS. Interacting mediators of allostasis and allostatic load: towards an understanding of resilience in aging. Metabo- lism 2003;52:10-16.
61. Glover DA, Stuber M, Poland RE. Allostatic load in women with and without PTSD symptoms. Psychiatry 2006;69:191-203.