Heteromers of μ-δ Opioid receptors: New pharmacology and novel therapeutic possibilities

British Journal of Pharmacology

Volumn 172, Issue 2, 2015, Pages 375-387

  Fujita, Wakako ^a   Gomes, Ivone ^a   Devi, Lakshmi A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

antinociception; dependence; heteromer; high throughput screening; opioid; signalling; tolerance; trafficking

Indexed keywords

BETA ARRESTIN; CALCIUM; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; LIGAND;

ANALGESIC ACTIVITY; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; HETEROMERIZATION; HIGH THROUGHPUT SCREENING; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PAIN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RECEPTOR OCCUPANCY; REVIEW; SIGNAL TRANSDUCTION; THREE DIMENSIONAL IMAGING; ANIMAL; METABOLISM; PROTEIN MULTIMERIZATION;

ANIMALS; HUMANS; LIGANDS; PAIN; PROTEIN MULTIMERIZATION; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU;

EID: 84920141912     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12663     Document Type: Review

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