Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- And δ-opioid receptors at supraspinal level

British Journal of Pharmacology

Volumn 166, Issue 1, 2012, Pages 309-326

  Ballesta, J J ^a   Cremades, J ^a   Rodriguez Munoz M ^b   Garzon J ^b,c   Faura, Clara C ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c INSTITUTO CAJAL   (Spain)

Author keywords

anti nociception; inter individual variability; opioid receptors; opioid receptors interactions; opioids; rats; supraspinal

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; DELTA OPIATE RECEPTOR; DELTORPHIN; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALTRINDOLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; MALE; NONHUMAN; NUCLEIC ACID SYNTHESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION; RAT; RECEPTOR BINDING;

ANALGESICS, OPIOID; ANIMALS; BRAIN; CYCLIC AMP; DISEASE MODELS, ANIMAL; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); IMMUNOPRECIPITATION; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTOR CROSS-TALK; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; SPECIES SPECIFICITY; SPINAL CORD;

EID: 84859724935     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01750.x     Document Type: Article

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