-
1
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
Li M, et al. (2000) Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 288(5464):335-339.
-
(2000)
Science
, vol.288
, Issue.5464
, pp. 335-339
-
-
Li, M.1
-
2
-
-
0032522704
-
Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1
-
Graves JD, et al. (1998) Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. EMBO J 17(8):2224-2234.
-
(1998)
EMBO J
, vol.17
, Issue.8
, pp. 2224-2234
-
-
Graves, J.D.1
-
3
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, et al. (2006) Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441(7095):885-889.
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 885-889
-
-
Hara, T.1
-
4
-
-
70349627027
-
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
-
Hetz C, et al. (2009) XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev 23(19):2294-2306.
-
(2009)
Genes Dev
, vol.23
, Issue.19
, pp. 2294-2306
-
-
Hetz, C.1
-
5
-
-
79955522014
-
Autophagy in spinal cord motor neurons in sporadic amyotrophic lateral sclerosis
-
Sasaki S (2011) Autophagy in spinal cord motor neurons in sporadic amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 70(5):349-359.
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, Issue.5
, pp. 349-359
-
-
Sasaki, S.1
-
6
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine B, Klionsky DJ (2004) Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev Cell 6(4):463-477.
-
(2004)
Dev Cell
, vol.6
, Issue.4
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
7
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, et al. (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19(21):5720-5728.
-
(2000)
EMBO J
, vol.19
, Issue.21
, pp. 5720-5728
-
-
Kabeya, Y.1
-
8
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, et al. (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4(2):151-175.
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 151-175
-
-
Klionsky, D.J.1
-
9
-
-
27944504351
-
P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjørkøy G, et al. (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 171(4):603-614.
-
(2005)
J Cell Biol
, vol.171
, Issue.4
, pp. 603-614
-
-
Bjørkøy, G.1
-
10
-
-
42249102078
-
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
-
Turner BJ, Talbot K (2008) Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Prog Neurobiol 85(1):94-134.
-
(2008)
Prog Neurobiol
, vol.85
, Issue.1
, pp. 94-134
-
-
Turner, B.J.1
Talbot, K.2
-
11
-
-
0030851761
-
Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis
-
Beal MF, et al. (1997) Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann Neurol 42(4):644-654.
-
(1997)
Ann Neurol
, vol.42
, Issue.4
, pp. 644-654
-
-
Beal, M.F.1
-
12
-
-
0033807443
-
Increased oxidative damage to DNA in ALS patients
-
Bogdanov M, et al. (2000) Increased oxidative damage to DNA in ALS patients. Free Radic Biol Med 29(7):652-658.
-
(2000)
Free Radic Biol Med
, vol.29
, Issue.7
, pp. 652-658
-
-
Bogdanov, M.1
-
13
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Ferrante RJ, et al. (1997) Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem 69(5):2064-2074.
-
(1997)
J Neurochem
, vol.69
, Issue.5
, pp. 2064-2074
-
-
Ferrante, R.J.1
-
14
-
-
71949114463
-
Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse
-
Oh S, et al. (2009) Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Mol Cell Biol 29(23):6309-6320.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.23
, pp. 6309-6320
-
-
Oh, S.1
-
15
-
-
33947363215
-
Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis
-
Shin JH, et al. (2007) Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis. Mol Pharmacol 71(4):965-975.
-
(2007)
Mol Pharmacol
, vol.71
, Issue.4
, pp. 965-975
-
-
Shin, J.H.1
-
16
-
-
77955299009
-
Automated quantitative gait analysis in animal models of movement disorders
-
Vandeputte C, et al. (2010) Automated quantitative gait analysis in animal models of movement disorders. BMC Neurosci 11:92.
-
(2010)
BMC Neurosci
, vol.11
, pp. 92
-
-
Vandeputte, C.1
|