A FLIPR assay for evaluating agonists and antagonists of GPCR heterodimers

Methods in Molecular Biology

Volumn 995, Issue , 2013, Pages 43-54

  Harvey, Jessica H ^a   Van Rijn, Richard M ^a   Whistler, Jennifer L ^a  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

Author keywords

Bivalent ligands; Calcium mobilization; G protein coupled receptor; GPCR; Heteromer; High throughput screening; HTS; Oligomerization

Indexed keywords

G PROTEIN COUPLED RECEPTOR; HETERODIMER; LIGAND; REAGENT;

AGONIST; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL GROWTH; CHEMICAL STRUCTURE; CHIMERA; EMBRYO; FLIPR ASSAY; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MEASUREMENT; MOLECULAR LIBRARY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; SIGNAL TRANSDUCTION;

BENZYLIDENE COMPOUNDS; CALCIUM SIGNALING; CELL CULTURE TECHNIQUES; DRUG EVALUATION, PRECLINICAL; ENKEPHALIN, D-PENICILLAMINE (2,5)-; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; NALTREXONE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, OPIOID, DELTA; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; TRANSFECTION;

EID: 84877043027     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-345-9_4     Document Type: Article

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