Novel screening assay for the selective detection of G-protein-coupled receptor heteromer signaling

Journal of Pharmacology and Experimental Therapeutics

Volumn 344, Issue 1, 2013, Pages 179-188

  Van Rijn, Richard M ^a   Harvey, Jessica H ^a   Brissett, Daniela I ^a   DeFriel, Julia N ^a   Whistler, Jennifer L ^a  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ADL 5859; ARM 1000390; CALCIUM; CHIMERIC PROTEIN; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTORPHIN 2; G PROTEIN COUPLED RECEPTOR; HETEROMER; HYBRID PROTEIN; MU OPIATE RECEPTOR; N,N DIETHYL 4 (PHENYL 4 PIPERIDINYLIDENEMETHYL)BENZAMIDE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG TARGETING; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BENZAMIDES; CALCIUM; CALCIUM SIGNALING; CLONING, MOLECULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENKEPHALIN, LEUCINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HEK293 CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTANT CHIMERIC PROTEINS; PIPERAZINES; POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, OPIOID, DELTA; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 84871686505     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.198655     Document Type: Article

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