Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

Kidney International

Volumn 87, Issue 1, 2015, Pages 74-84

  Shahzad, Khurrum ^a,b   Bock, Fabian ^a,c   Dong, Wei ^a   Wang, Hongjie ^a,d   Kopf, Stefan ^c   Kohli, Shrey ^a   Al Dabet, Moh'D Mohanad ^a   Ranjan, Satish ^a   Wolter, Juliane ^a   Wacker, Christian ^a   Biemann, Ronald ^a   Stoyanov, Stoyan ^e   Reymann, Klaus ^e   Söderkvist, Peter ^f   Groß, Olaf ^g   Schwenger, Vedat ^c   Pahernik, Sascha ^c   Nawroth, Peter P ^c   Gröne, Herman Josef ^h   Madhusudhan, Thati ^a   Isermann, Berend ^a   more..

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNIVERSITY OF HEALTH SCIENCES   (Pakistan)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^e GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^f LINKÖPING UNIVERSITY   (Sweden)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^h GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Diabetic nephropathy; endothelial cell; inflammasome; mitochondrial ROS; Nlrp3; podocyte

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NEPHRIN; REACTIVE OXYGEN METABOLITE; CARRIER PROTEIN; NLRP3 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; EXTRACELLULAR MATRIX; HUMAN; HYPERGLYCEMIA; IN VIVO STUDY; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; NONMYELOID DERIVED CELL; PODOCYTE; PROTEIN CLEAVAGE; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; ENDOTHELIUM CELL; GLOMERULUS; IMMUNOLOGY; SEVERITY OF ILLNESS INDEX;

ANIMALS; CARRIER PROTEINS; DIABETIC NEPHROPATHIES; ENDOTHELIAL CELLS; HUMANS; INFLAMMASOMES; KIDNEY GLOMERULUS; MICE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PODOCYTES; SEVERITY OF ILLNESS INDEX;

EID: 84920134906     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2014.271     Document Type: Article

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