Polyomavirus life cycle

DNA Tumor Viruses

Volumn , Issue , 2009, Pages 1-24

  Fanning, Ellen ^a   Zhao, Xiaorong ^a   Jiang, Xiaohua ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84919967377     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-68945-6_1     Document Type: Chapter

References (160)

1. Acheson, N.H. (2007) Polyomaviruses. In: N.H. Acheson, Fundamentals of Molecular Virology. John Wiley & Sons, Inc., Hoboken, NJ, 98-113.
2. Ahuja, D., Saenz-Robles, M.T. and Pipas, J.M. (2005) SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene, 24, 7729-7745.
3. Alexiadis, V., Waldmann, T., Andersen, J., Mann, M., Knippers, R. and Gruss, C. (2000) The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin-specific manner. Genes Dev, 14, 1308-1312.
4. Ali, S.H., Kasper, J.S., Arai, T. and DeCaprio, J.A. (2004) Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation. J Virol, 78, 2749-2757.
5. Allander, T., Andreasson, K., Gupta, S., Bjerkner, A., Bogdanovic, G., Persson, M.A., Dalianis, T., Ramqvist, T. and Andersson, B. (2007) Identification of a third human polyomavirus. J Virol, 81, 4130-4136.
6. Arunkumar, A.I., Klimovich, V., Jiang, X., Ott, R.D., Mizoue, L., Fanning, E. and Chazin, W.J. (2005) Insights into hRPA32 C-terminal domain-mediated assembly of the simian virus 40 replisome. Nat Struct Mol Biol, 12, 332-339.
7. Balakrishnan, L. and Milavetz, B. (2005) Programmed remodeling of hyperacetylated histone H4 and H3 organization on the SV40 genome during lytic infection. Virology, 334, 111-123.
8. Balakrishnan, L. and Milavetz, B. (2006) Reorganization of RNA polymerase II on the SV40 genome occurs coordinately with the early to late transcriptional switch. Virology, 345, 31-43.
9. Balakrishnan, L. and Milavetz, B. (2007) Histone hyperacetylation in the coding region of chromatin undergoing transcription in SV40 minichromosomes is a dynamic process regulated directly by the presence of RNA polymerase II. J Mol Biol, 365, 18-30.
10. Bartek, J. and Lukas, J. (2007) DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol, 19, 238-245.
11. Bochkareva, E., Martynowski, D., Seitova, A. and Bochkarev, A. (2006) Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA. Embo J, 25, 5961-5969.
12. Boe, S.O., Haave, M., Jul-Larsen, A., Grudic, A., Bjerkvig, R. and Lonning, P.E. (2006) Promyelocytic leukemia nuclear bodies are predetermined processing sites for damaged DNA. J Cell Sci, 119, 3284-3295.
13. Breau, W.C., Atwood, W.J. and Norkin, L.C. (1992) Class I major histocompatibility proteins are an essential component of the simian virus 40 receptor. J Virol, 66, 2037-2045.
14. Bukau, B., Weissman, J. and Horwich, A. (2006) Molecular chaperones and protein quality control. Cell, 125, 443-451.
15. Bullock, P.A. (1997) The initiation of simian virus 40 DNA replication in vitro. Crit Rev Biochem Mol Biol, 32, 503-568.
16. Campbell, K.S., Mullane, K.P., Aksoy, I.A., Stubdal, H., Zalvide, J., Pipas, J.M., Silver, P.A., Roberts, T.M., Schaffhausen, B.S. and DeCaprio, J.A. (1997) DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication. Genes Dev, 11, 1098-1110.
17. Carbone, M., Reale, A., Di Sauro, A., Sthandier, O., Garcia, M.I., Maione, R., Caiafa, P. and Amati, P. (2006) PARP-1 interaction with VP1 capsid protein regulates polyomavirus early gene expression. J Mol Biol, 363, 773-785.
18. Chen, X.S., Stehle, T. and Harrison, S.C. (1998) Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry. Embo J, 17, 3233-3240.
19. Chen, Y., Xu, Y., Bao, Q., Xing, Y., Li, Z., Lin, Z., Stock, J.B., Jeffrey, P.D. and Shi, Y. (2007) Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Nat Struct Mol Biol, 14, 527-534.
20. Clarey, M.G., Erzberger, J.P., Grob, P., Leschziner, A.E., Berger, J.M., Nogales, E. and Botchan, M. (2006) Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex. Nat Struct Mol Biol, 13, 684-690.
21. Cole, C.N.a.C., S.D. (2001) Polyomaviridae: The viruses and their replication. In: D.M. Knipe, P.M. Howley, D.E. Griffin, R.A. Lamb, M.A. Martin, B. Roizman, and S.E. Straus (eds.) Fields Virology, 4th ed., . Lippincott Williams & Wilkins, Philadelphia, PA, 2141-2174.
22. Cotsiki, M., Lock, R.L., Cheng, Y., Williams, G.L., Zhao, J., Perera, D., Freire, R., Entwistle, A., Golemis, E.A., Roberts, T.M., Jat, P.S. and Gjoerup, O.V. (2004) Simian virus 40 large Tantigen targets the spindle assembly checkpoint protein Bub1. Proc Natl Acad Sci USA, 101, 947-952.
23. Dahl, J., You, J. and Benjamin, T.L. (2005) Induction and utilization of an ATM signaling pathway by polyomavirus. J Virol, 79, 13007-13017.
24. Damm, E.M., Pelkmans, L., Kartenbeck, J., Mezzacasa, A., Kurzchalia, T. and Helenius, A. (2005) Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae. J Cell Biol, 168, 477-488.
25. Daniels, R., Rusan, N.M., Wilbuer, A.K., Norkin, L.C., Wadsworth, P. and Hebert, D.N. (2006) Simian virus 40 late proteins possess lytic properties that render them capable of permeabilizing cellular membranes. J Virol, 80, 6575-6587.
26. Dehde, S., Rohaly, G., Schub, O., Nasheuer, H.-P., Bohn, W., Chemnitz, J., Deppert, W. and Dornreiter, I. (2001) Two immunologically distinct humanDNApolymerase alpha-primase subpopulations are involved in cellular DNA replication. Mol Cell Biol, 21, 2581-2593.
27. Dias, D.C., Dolios, G., Wang, R. and Pan, Z.Q. (2002) CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. Proc Natl Acad Sci USA, 99, 16601-16606.
28. Dickmanns, A., Zeitvogel, A., Simmersbach, F., Weber, R., Arthur, A.K., Dehde, S., Wildeman, A.G. and Fanning, E. (1994) The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen. J Virol, 68, 5496-5508.
29. Digweed, M., Demuth, I., Rothe, S., Scholz, R., Jordan, A., Grotzinger, C., Schindler, D., Grompe, M. and Sperling, K. (2002) SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11. Oncogene, 21, 4873-4878.
30. Dilworth, S.M. (2002) Polyoma virus middle T antigen and its role in identifying cancerrelated molecules. Nat Rev Cancer, 2, 951-956.
31. Dobbelstein, M., Arthur, A.K., Dehde, S., van Zee, K., Dickmanns, A. and Fanning, E. (1992) Intracistronic complementation reveals a new function of SV40 T antigen that cooperates with Rb and p53 binding to stimulateDNAsynthesis in quiescent cells. Oncogene, 7, 837-847.
32. Dugan, A.S., Eash, S. and Atwood, W.J. (2006) Update on BK virus entry and intracellular trafficking. Transpl Infect Dis, 8, 62-67.
33. Eash, S. and Atwood, W.J. (2005) Involvement of cytoskeletal components in BK virus infectious entry. J Virol, 79, 11734-11741.
34. Elphick, G.F., Querbes, W., Jordan, J.A., Gee, G.V., Eash, S., Manley, K., Dugan, A., Stanifer, M., Bhatnagar, A., Kroeze, W.K., Roth, B.L. and Atwood, W.J. (2004) The human polyomavirus, JCV, uses serotonin receptors to infect cells. Science, 306, 1380-1383.
35. Enemark, E.J. and Joshua-Tor, L. (2006) Mechanism of DNA translocation in a replicative hexameric helicase. Nature, 442, 270-275.
36. Erzberger, J.P., Mott, M.L. and Berger, J.M. (2006) Structural basis for ATP-dependent DnaA assembly and replication-origin remodeling. Nat Struct Mol Biol, 13, 676-683.
37. Everett, R.D. (2006) Interactions between DNA viruses, ND10 and the DNA damage response. Cell Microbiol, 8, 365-374.
38. Fanning, E. (1994) Control of SV40 DNA replication by protein phosphorylation: A model for cellular DNA replication? Trends Cell Biol, 4, 250-255.
39. Fanning, E., Klimovich, V. and Nager, A.R. (2006) A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res, 34, 4126-4137.
40. Fanning, E. and Knippers, R. (1992) Structure and function of simian virus 40 large tumor antigen. Annu Rev Biochem, 61, 55-85.
41. Forsburg, S.L. (2004) Eukaryotic MCM Proteins: Beyond Replication Initiation. Microbiol. Mol. Biol. Rev., 68, 109-131.
42. Françon, P., Lemaître, J.-M., Dreyer, C., Maiorano, D., Cuvier, O. and Méchali, M. (2004) A hypophosphorylated form of RPA34 is a specific component of pre-replication centers. J Cell Sci, 117, 4909-4920.
43. Gai, D., Zhao, R., Li, D., Finkielstein, C.V. and Chen, X.S. (2004) Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell, 119, 47-60.
44. Garimella, R., Liu, X., Qiao, W., Liang, X., Zuiderweg, E.R., Riley, M.I. and Van Doren, S. R. (2006) Hsc70 contacts helix III of the J domain from polyomavirus T antigens: Addressing a dilemma in the chaperone hypothesis of how they release E2F from pRb. Biochemistry, 45, 6917-6929.
45. Gasparovic, M.L., Gee, G.V. and Atwood, W.J. (2006) JC virus minor capsid proteins Vp2 and Vp3 are essential for virus propagation. J Virol, 80, 10858-10861.
46. Gilbert, J. and Benjamin, T. (2004) Uptake pathway of polyomavirus via ganglioside GD1a. J Virol, 78, 12259-12267.
47. Gilbert, J.M., Goldberg, I.G. and Benjamin, T.L. (2003) Cell penetration and trafficking of polyomavirus. J Virol, 77, 2615-2622.
48. Gomez-Lorenzo, M.G., Valle, M., Frank, J., Gruss, C., Sorzano, C.O., Chen, X.S., Donate, L.E. and Carazo, J.M. (2003) Large T antigen on the simian virus 40 origin of replication: A 3D snapshot prior to DNA replication. Embo J, 22, 6205-6213.
49. Gordon-Shaag, A., Ben-Nun-Shaul, O., Roitman, V., Yosef, Y. and Oppenheim, A. (2002) Cellular transcription factor Sp1 recruits simian virus 40 capsid proteins to the viral packaging signal, ses. J Virol, 76, 5915-5924.
50. Gordon-Shaag, A., Yosef, Y., Abd El-Latif, M. and Oppenheim, A. (2003) The abundant nuclear enzyme PARP participates in the life cycle of simian virus 40 and is stimulated by minor capsid protein VP3. J Virol, 77, 4273-4282.
51. Heller, R.C. and Marians, K.J. (2006) Replisome assembly and the direct restart of stalled replication forks. Nat Rev Mol Cell Biol, 7, 932-943.
52. Hennessy, F., Nicoll, W.S., Zimmermann, R., Cheetham, M.E. and Blatch, G.L. (2005) Not all J domains are created equal: implications for the specificity of Hsp40-Hsp70 interactions. Protein Sci, 14, 1697-1709.
53. Huang, S.G., Weisshart, K., Gilbert, I. and Fanning, E. (1998) Stoichiometry and mechanism of assembly of SV40 T antigen complexes with the viral origin of DNA replication and DNA polymerase alpha-primase. Biochemistry, 37, 15345-15352.
54. Ishizu, K.I., Watanabe, H., Han, S.I., Kanesashi, S.N., Hoque, M., Yajima, H., Kataoka, K. and Handa, H. (2001) Roles of disulfide linkage and calcium ion-mediated interactions in assembly and disassembly of virus-like particles composed of simian virus 40 VP1 capsid protein. J Virol, 75, 61-72.
55. Ishov, A.M. and Maul, G.G. (1996) The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition. J Cell Biol, 134, 815-826.
56. Jiang, X., Klimovich, V., Arunkumar, A.I., Hysinger, E.B., Wang, Y., Ott, R.D., Guler, G.D., Weiner, B., Chazin, W.J. and Fanning, E. (2006) Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complex. Embo J, 25, 5516-5526.
57. Johne, R., Wittig, W., Fernandez-de-Luco, D., Hofle, U. and Muller, H. (2006) Characterization of two novel polyomaviruses of birds by using multiply primed rolling-circle amplification of their genomes. J Virol, 80, 3523-3531.
58. Kasamatsu, H., Woo, J., Nakamura, A., Muller, P., Tevethia, M.J. and Liddington, R.C. (2006) A structural rationale for SV40 Vp1 temperature-sensitive mutants and their complementation. Protein Sci, 15, 2207-2213.
59. Kasper, J.S., Arai, T. and DeCaprio, J.A. (2006) A novel p53-binding domain in CUL7. Biochem Biophys Res Commun, 348, 132-138.
60. Kasper, J.S., Kuwabara, H., Arai, T., Ali, S.H. and DeCaprio, J.A. (2005) Simian virus 40 large T antigen's association with the CUL7 SCF complex contributes to cellular transformation. J Virol, 79, 11685-11692.
61. Kastan, M.B. and Bartek, J. (2004) Cell-cycle checkpoints and cancer. Nature, 432, 316-323.
62. Kawano, M.A., Inoue, T., Tsukamoto, H., Takaya, T., Enomoto, T., Takahashi, R.U., Yokoyama, N., Yamamoto, N., Nakanishi, A., Imai, T., Wada, T., Kataoka, K. and Handa, H. (2006) The VP2/VP3 minor capsid protein of simian virus 40 promotes the in vitro assembly of themajor capsid protein VP1 into particles. J Biol Chem, 281, 10164-10173.
63. Kim, H.-Y., Ahn, B.-Y. and Cho, Y. (2001) Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen. EMBO J, 20, 295-304.
64. Kitamura, E., Blow, J.J. and Tanaka, T.U. (2006) Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories. Cell, 125, 1297-1308.
65. Koch, H.B., Zhang, R., Verdoodt, B., Bailey, A., Zhang, C.D., Yates, J.R. 3rd, Menssen, A. and Hermeking, H. (2007) Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach. Cell Cycle, 6, 205-217.
66. Kohrman, D.C. and Imperiale, M.J. (1992) Simian virus 40 large T antigen stably complexes with a 185-kilodalton host protein. J Virol, 66, 1752-1760.
67. Kumar, A., Meinke, G., Reese, D.K., Moine, S., Phelan, P.J., Fradet-Turcotte, A., Archambault, J., Bohm, A. and Bullock, P.A. (2007) Model for T-antigen-dependent melting of the simian virus 40 core origin based on studies of the interaction of the betahairpin with DNA. J Virol, 81, 4808-4818.
68. Lambert, S., Froget, B. and Carr, A.M. (2007) Arrested replication fork processing: Interplay between checkpoints and recombination. DNA Repair (Amst), 6, 1042-1061.
69. Lanson, N.A. Jr., Egeland, D.B., Royals, B.A. and Claycomb, W.C. (2000) The MRE11- NBS1-RAD50 pathway is perturbed in SV40 large T antigen-immortalized AT-1, AT-2 and HL-1 cardiomyocytes. Nucleic Acids Res, 28, 2882-2892.
70. Lee, J.H. and Paull, T.T. (2005) ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science, 308, 551-554.
71. Lehman, J.M., Laffin, J. and Friedrich, T.D. (2000) Simian virus 40 induces multiple S phases with the majority of viralDNAreplication in the G2 and second S phase in CV-1 cells. Exp Cell Res, 258, 215-222.
72. Li, D., Zhao, R., Lilyestrom, W., Gai, D., Zhang, R., DeCaprio, J.A., Fanning, E., Jochimiak, A., Szakonyi, G. and Chen, X.S. (2003a) Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen. Nature, 423, 512-518.
73. Li, H., Xie, B., Zhou, Y., Rahmeh, A., Trusa, S., Zhang, S., Gao, Y., Lee, E.Y. and Lee, M.Y. (2006) Functional roles of p12, the fourth subunit of humanDNApolymerase delta. J Biol Chem, 281, 14748-14755.
74. Li, P.P., Nakanishi, A., Fontanes, V. and Kasamatsu, H. (2005) Pairs of Vp1 cysteine residues essential for simian virus 40 infection. J Virol, 79, 3859-3864.
75. Li, P.P., Naknanishi, A., Tran, M.A., Ishizu, K., Kawano, M., Phillips, M., Handa, H., Liddington, R.C. and Kasamatsu, H. (2003b) Importance of Vp1 calcium-binding residues in assembly, cell entry, and nuclear entry of simian virus 40. J Virol, 77, 7527-7538.
76. Lilyestrom, W., Klein, M.G., Zhang, R., Joachimiak, A. and Chen, X.S. (2006) Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev, 20, 2373-2382.
77. Liu, G. and Warbrick, E. (2006) The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins. Biochem Biophys Res Commun, 349, 360-366.
78. Luo, X., Sanford, D.G., Bullock, P.A. and Bachovchin, W.W. (1996) Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat Struct Biol, 3, 1034-1039.
79. Mannova, P., Liebl, D., Krauzewicz, N., Fejtova, A., Stokrova, J., Palkova, Z., Griffin, B.E. and Forstova, J. (2002) Analysis of mouse polyomavirus mutants with lesions in the minor capsid proteins. J Gen Virol, 83, 2309-2319.
80. Maulbecker, C., Mohr, I., Gluzman, Y., Bartholomew, J. and Botchan, M. (1992)Adeletion in the simian virus 40 large T antigen impairs lytic replication in monkey cells in vivo but enhances DNA replication in vitro: new complementation function of T antigen.J Virol, 66, 2195-2207.
81. Mayer, M.P. and Bukau, B. (2005) Hsp70 chaperones: cellular functions and molecular mechanism. Cell Mol Life Sci, 62, 670-684.
82. McGeoch, A.T., Trakselis, M.A., Laskey, R.A. and Bell, S.D. (2005) Organization of the archaealMCMcomplex on DNA and implications for the helicase mechanism. Nat Struct Mol Biol, 12, 756-762.
83. Meinke, G., Bullock, P.A. and Bohm, A. (2006) Crystal structure of the simian virus 40 large T-antigen origin-binding domain. J Virol, 80, 4304-4312.
84. Meinke, G., Phelan, P., Moine, S., Bochkareva, E., Bochkarev, A., Bullock, P.A. and Bohm, A. (2007) The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. PLoS Biol, 5, e23.
85. Meister, P., Taddei, A., Ponti, A., Baldacci, G. and Gasser, S.M. (2007) Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast. Embo J, 26, 1315-1326.
86. Milavetz, B.I. (2002) SP1 and AP-1 elements direct chromatin remodeling in SV40 chromosomes during the first 6 hours of infection. Virology, 294, 170-179.
87. Moarefi, I.F., Small, D., Gilbert, I., Hopfner, M., Randall, S.K., Schneider, C., Russo, A.A., Ramsperger, U., Arthur, A.K., Stahl, H., Kelly, T.J., and Fanning, E. (1993) Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding. J Virol, 67, 4992-5002.
88. Murakami, Y., Chen, L.F., Sanechika, N., Kohzaki, H. and Ito, Y. (2007) Transcription factor Runx1 recruits the polyomavirus replication origin to replication factories. J Cell Biochem, 100, 1313-1323.
89. Musacchio, A. and Salmon, E.D. (2007) The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol, 8, 379-393.
90. Nakanishi, A., Itoh, N., Li, P.P., Handa, H., Liddington, R.C. and Kasamatsu, H. (2007) Minor capsid proteins of simian virus 40 are dispensable for nucleocapsid assembly and cell entry but are required for nuclear entry of the viral genome. J Virol, 81, 3778-3785.
91. Nakanishi, A., Nakamura, A., Liddington, R. and Kasamatsu, H. (2006) Identification of amino acid residues within simian virus 40 capsid proteins Vp1, Vp2, and Vp3 that are required for their interaction and for viral infection. J Virol, 80, 8891-8898.
92. Nakanishi, A., Shum, D., Morioka, H., Otsuka, E. and Kasamatsu, H. (2002) Interaction of the Vp3 nuclear localization signal with the importin alpha 2/beta heterodimer directs nuclear entry of infecting simian virus 40. J Virol, 76, 9368-9377.
93. Norkin, L.C., Anderson, H.A., Wolfrom, S.A. and Oppenheim, A. (2002) Caveolar endocytosis of simian virus 40 is followed by brefeldin A-sensitive transport to the endoplasmic reticulum, where the virus disassembles. J Virol, 76, 5156-5166.
94. Norkin, L.C. and Kuksin, D. (2005) The caveolae-mediated sv40 entry pathway bypasses the golgi complex en route to the endoplasmic reticulum. Virol J, 2, 38.
95. O'Donnell, M. and Jeruzalmi, D. (2006) Helical proteins initiate replication of DNA helices. Nat Struct Mol Biol, 13, 665-667.
96. Okubo, E., Lehman, J.M. and Friedrich, T.D. (2003) Negative regulation of mitotic promoting factor by the checkpoint kinase chk1 in simian virus 40 lytic infection.JVirol, 77, 1257-1267.
97. Olson, E., Nievera, C.J., Klimovich, V., Fanning, E. and Wu, X. (2006) RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint. J Biol Chem, 281, 39517-39533.
98. Orphanides, G. and Reinberg, D. (2000) RNA polymerase II elongation through chromatin. Nature, 407, 471-475.
99. Ott, R.D., Rehfuess, C., Podust, V.N., Clark, J.E. and Fanning, E. (2002) Role of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replication. Mol Cell Biol, 22, 5669-5678.
100. Parton, R.G. and Simons, K. (2007) The multiple faces of caveolae. Nat Rev Mol Cell Biol, 8, 185-194.
101. Pelkmans, L., Kartenbeck, J. and Helenius, A. (2001) Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nat Cell Biol, 3, 473-483.
102. Pipas, J.M. (1992) Common and unique features of T antigens encoded by the polyomavirus group. J Virol, 66, 3979-3985.
103. Pipas, J.M. and Fanning, E. (unpublished data).
104. Podust, V.N., Chang, L.S., Ott, R., Dianov, G.L. and Fanning, E. (2002) Reconstitution of human DNA polymerase delta using recombinant baculoviruses: The p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme. J Biol Chem, 277, 3894-3901.
105. Pospiech, H. and Syvaoja, J.E. (2003) DNA polymerase epsilon - more than a polymerase. Scientific World Journal, 3, 87-104.
106. Poulin, D.L., Kung, A.L. and DeCaprio, J.A. (2004) p53 targets simian virus 40 large T antigen for acetylation by CBP. J Virol, 78, 8245-8253.
107. Querbes, W., O'Hara, B.A., Williams, G. and Atwood, W.J. (2006) Invasion of host cells by JC virus identifies a novel role for caveolae in endosomal sorting of noncaveolar ligands. J Virol, 80, 9402-9413.
108. Reese, D.K., Meinke, G., Kumar, A., Moine, S., Chen, K., Sudmeier, J.L., Bachovchin, W., Bohm, A. and Bullock, P.A. (2006) Analyses of the interaction between the origin binding domain from simian virus 40 T antigen and single-stranded DNA provide insights into DNA unwinding and initiation of DNA replication. J Virol, 80, 12248-12259.
109. Reese, D.K., Sreekumar, K.R. and Bullock, P.A. (2004) Interactions required for binding of simian virus 40 T antigen to the viral origin and molecular modeling of initial assembly events. J Virol, 78, 2921-2934.
110. Roitman-Shemer, V., Stokrova, J., Forstova, J. and Oppenheim, A. (2007) Assemblages of simian virus 40 capsid proteins and viralDNA visualized by electron microscopy. Biochem Biophys Res Commun, 353, 424-430.
111. Roy, R., Trowbridge, P., Yang, Z., Champoux, J.J. and Simmons, D.T. (2003) The cap region of topoisomerase I binds to sites near both ends of simian virus 40 T antigen. J Virol, 77, 9809-9816.
112. Sahli, R., Freund, R., Dubensky, T., Garcea, R., Bronson, R. and Benjamin, T. (1993) Defect in entry and altered pathogenicity of a polyoma virus mutant blocked in VP2 myristylation. Virology, 192, 142-153.
113. Sainis, L., Angelidis, C., Pagoulatos, G.N. and Lazaridis, L. (2000) HSC70 interactions with SV40 viral proteins differ between permissive and nonpermissive mammalian cells. Cell Stress Chaperones, 5, 132-138.
114. Schirmbeck, R. and Deppert, W. (1987) Specific interaction of simian virus 40 large T antigen with cellular chromatin and nuclear matrix during the course of infection. J Virol, 61, 3561-3569.
115. Schirmbeck, R. and Deppert, W. (1989) Nuclear subcompartmentalization of simian virus 40 large T antigen: evidence for in vivo regulation of biochemical activities. J Virol, 63, 2308-2316.
116. Schirmbeck, R. and Deppert, W. (1991) Structural topography of simian virus 40 DNA replication. J Virol, 65, 2578-2588.
117. Schneider, J. and Fanning, E. (1988) Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity. J Virol, 62, 1598-1605.
118. Schuck, S. and Stenlund, A. (2005) Role of papillomavirus E1 initiator dimerization in DNA replication. J Virol, 79, 8661-8664.
119. Sclafani, R.A., Fletcher, R.J. and Chen, X.S. (2004) Two heads are better than one: regulation of DNA replication by hexameric helicases. Genes Dev, 18, 2039-2045.
120. Sharma, D.K., Brown, J.C., Choudhury, A., Peterson, T.E., Holicky, E., Marks, D. L., Simari, R., Parton, R.G. and Pagano, R.E. (2004) Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol. Mol Biol Cell, 15, 3114-3122.
121. Shen, J., Gai, D., Patrick, A., Greenleaf, W.B. and Chen, X.S. (2005) The roles of the residues on the channel beta-hairpin and loop structures of simian virus 40 hexameric helicase. Proc Natl Acad Sci USA, 102, 11248-11253.
122. Shi, Y., Dodson, G.E., Shaikh, S., Rundell, K. and Tibbetts, R.S. (2005) Ataxia-telangiectasiamutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.JBiol Chem, 280, 40195-40200.
123. Shibahara, K. and Stillman, B. (1999) Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. Cell, 96, 575-585.
124. Shibahara, K., Verreault, A. and Stillman, B. (2000) The N-terminal domains of histones H3 and H4 are not necessary for chromatin assembly factor-1- mediated nucleosome assembly onto replicated DNA in vitro. Proc Natl Acad Sci USA, 97, 7766-7771.
125. Shiloh, Y. (2003) ATM: ready, set, go. Cell Cycle, 2, 116-117.
126. Simmons, D.T. (2000) SV40 large T antigen functions in DNA replication and transformation. Adv Virus Res, 55, 75-134.
127. Simmons, D.T., Gai, D., Parsons, R., Debes, A. and Roy, R. (2004) Assembly of the replication initiation complex on SV40 origin DNA. Nucl Acids Res, 32, 1103-1112.
128. Skaar, J.R., Florens, L., Tsutsumi, T., Arai, T., Tron, A., Swanson, S.K., Washburn, M.P. and DeCaprio, J.A. (2007) PARC and CUL7 form atypical cullin RING ligase complexes. Cancer Res, 67, 2006-2014.
129. Skoczylas, C., Fahrbach, K.M. and Rundell, K. (2004) Cellular targets of the SV40 small-t antigen in human cell transformation. Cell Cycle, 3, 606-610.
130. Skoczylas, C., Henglein, B. and Rundell, K. (2005) PP2A-dependent transactivation of the cyclinApromoter by SV40 ST is mediated by a cell cycle-regulated E2F site. Virology, 332, 596-601.
131. Sontag, J.M. and Sontag, E. (2006) Regulation of cell adhesion by PP2A and SV40 small tumor antigen: An important link to cell transformation. Cell Mol Life Sci, 63, 2979-2991.
132. Speck, C., Chen, Z., Li, H. and Stillman, B. (2005) ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA. Nat Struct Mol Biol, 12, 965-971.
133. Stehle, T., Gamblin, S.J., Yan, Y. and Harrison, S.C. (1996) The structure of simian virus 40 refined at 3.1 A resolution. Structure, 4, 165-182.
134. Stehle, T. and Harrison, S.C. (1997) High-resolution structure of a polyomavirus VP1-oligosaccharide complex: implications for assembly and receptor binding.Embo J, 16, 5139-5148.
135. Stenlund, A. (2003) Initiation of DNA replication: lessons from viral initiator proteins. Nat Rev Mol Cell Biol, 4, 777-785.
136. Stewart, M. (2007) Molecular mechanism of the nuclear protein import cycle. Nat Rev Mol Cell Biol, 8, 195-208.
137. Stracker, T.H., Theunissen, J.W., Morales, M. and Petrini, J.H. (2004) The Mre11 complex and the metabolism of chromosome breaks: The importance of communicating and holding things together. DNA Repair (Amst), 3, 845-854.
138. Sullivan, C.S. and Pipas, J.M. (2002) T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis. Microbiol Mol Biol Rev, 66, 179-202.
139. Tagawa, A., Mezzacasa, A., Hayer, A., Longatti, A., Pelkmans, L. and Helenius, A. (2005) Assembly and trafficking of caveolar domains in the cell: caveolae as stable, cargotriggered, vesicular transporters. J Cell Biol, 170, 769-779.
140. Tang, Q., Bell, P., Tegtmeyer, P. and Maul, G.G. (2000) Replication but not transcription of simian virus 40 DNA is dependent on nuclear domain 10. J Virol, 74, 9694-9700.
141. Tooze, J. (1973) The Lytic Cycle of Polyoma Virus and SV40. The Molecular Biology of Tumor Viruses, Imperial Cancer Research Fund, Cold Spring Harbor Laboratory, 329.
142. Tooze, J. (1980) Lytic Cycle of SV40 and Polyoma Virus. DNA Tumor Viruses, European Molecular Biology Organization, Cold Spring Harbor Laboratory, 153.
143. Trenz, K., Smith, E., Smith, S. and Costanzo, V. (2006) ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation ofDNAbreaks. Embo J, 25, 1764-1774.
144. Tsai, B., Gilbert, J.M., Stehle, T., Lencer, W., Benjamin, T.L. and Rapoport, T.A. (2003) Gangliosides are receptors for murine polyoma virus and SV40. Embo J, 22, 4346-4355.
145. Tsai, S.C., Pasumarthi, K.B., Pajak, L., Franklin, M., Patton, B., Wang, H., Henzel, W.J., Stults, J.T. and Field, L.J. (2000) Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3-containing proapoptosis protein in the cytoplasm. J Biol Chem, 275, 3239-3246.
146. Valle, M., Chen, X.S., Donate, L.E., Fanning, E. and Carazo, J.M. (2006) Structural basis for the cooperative assembly of large T antigen on the origin of replication. J Mol Biol, 357, 1295-1305.
147. Vassin, V.M., Wold, M.S. and Borowiec, J.A. (2004) Replication protein A (RPA) phosphorylation prevents RPA association with replication centers.Mol Cell Biol, 24, 1930-1943.
148. Vestner, B., Waldmann, T. and Gruss, C. (2000) Histone octamer dissociation is not required for in vitro replication of simian virus 40 minichromosomes. J Biol Chem, 275, 8190-8195.
149. Waga, S. and Stillman, B. (1994)Anatomy of aDNAreplication fork revealed by reconstitution of SV40 DNA replication in vitro. Nature, 369, 207-212.
150. Wang, W., Manna, D. and Simmons, D.T. (2007) Role of the hydrophilic channels of simian virus 40 T-antigen helicase in DNA replication. J Virol, 81, 4510-4519.
151. Weisshart, K., Bradley, M.K., Weiner, B.M., Schneider, C., Moarefi, I., Fanning, E. and Arthur, A.K. (1996) An N-terminal deletion mutant of simian virus 40 (SV40) large T antigen oligomerizes incorrectly on SV40 DNA but retains the ability to bind to DNA polymerase alpha and replicate SV40 DNA in vitro. J Virol, 70, 3509-3516.
152. Weisshart, K., Taneja, P., Jenne, A., Herbig, U., Simmons, D.T. and Fanning, E. (1999) Two regions of simian virus 40 T antigen determine cooperativity of double-hexamer assembly on the viral origin of DNA replication and promote hexamer interactions during bidirectional origin DNA unwinding. J Virol, 73, 2201-2211.
153. Weitzman, M.D., Carson, C.T., Schwartz, R.A. and Lilley, C.E. (2004) Interactions of viruses with the cellular DNA repair machinery. DNA Repair (Amst), 3, 1165-1173.
154. Wessel, R., Schweizer, J. and Stahl, H. (1992) Simian virus 40 T-antigen DNA helicase is a hexamer which forms a binary complex during bidirectional unwinding from the viral origin of DNA replication. J Virol, 66, 804-815.
155. Whalen, K.A., de Jesus, R., Kean, J.A. and Schaffhausen, B.S. (2005) Genetic analysis of the polyomavirus DnaJ domain. J Virol, 79, 9982-9990.
156. Wu, X., Avni, D., Chiba, T., Yan, F., Zhao, Q., Lin, Y., Heng, H. and Livingston, D. (2004) SV40 T antigen interacts with Nbs1 to disrupt DNA replication control. Genes Dev, 18, 1305-1316.
157. Xie, B., Mazloum, N., Liu, L., Rahmeh, A., Li, H. and Lee, M.Y. (2002) Reconstitution and characterization of the humanDNApolymerase delta four-subunit holoenzyme. Biochemistry, 41, 13133-13142.
158. Yuzhakov, A., Kelman, Z., Hurwitz, J. and O'Donnell, M. (1999) Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. EMBO J, 18, 6189-6199.
159. Zhang, S., Zhou, Y., Trusa, S., Meng, X., Lee, E.Y. and Lee, M.Y. (2007) A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta. J Biol Chem, 282, 15330-15340.
160. Zhao, X. and Fanning, E. (unpublished data).