Solution structure of the origin DNA-binding domain of SV40 T-antigen

Nature Structural Biology

Volumn 3, Issue 12, 1996, Pages 1034-1039

  Luo, Xuelian ^a   Sanford, David G ^a   Bullock, Peter A ^a   Bachovchin, William W ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; DNA; OLIGONUCLEOTIDE; PROTON; VIRUS T ANTIGEN;

ARTICLE; DNA BINDING; DNA REPLICATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTON TRANSPORT; SIMIAN VIRUS 40;

AMINO ACID SEQUENCE; ANTIGENS, POLYOMAVIRUS TRANSFORMING; DNA, VIRAL; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SIMIAN VIRUS 40;

EID: 0030443808     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb1296-1034     Document Type: Article

References (15)

1. Jacob, F., Brenner, S. & Cuzin, F. On the regulation of DNA replication in bacteria Cold Spring Harbor Sym. Quant Biol. 28, 329-348 (1963).
2. Stillman, B. Replicator renaissance Nature 366, 506-507 (1993).
3. Kornberg, A. & Baker, T.A. DNA Replication (W.H. Freeman and Co., New York, 1992).
4. Tegtmeyer, P. Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon. J. Virol. 10, 591-598 (1972).
5. Borowiec, J.A., Dean, F.B., Bullock, P.A. & Hurwitz, J. Binding and unwinding-how T antigen engages the SV40 origin of DNA replication Cell 60, 181-184 (1990).
6. Fanning, E. & Knippers, R. Structure and function of simian virus 40 large tumor antigen. Ann. Rev. Biochem. 61, 55-85 (1992).
7. Brünger, AT. X-PLOR: A System for X-ray Crystallography and NMR X-PLOR Version 3.1 Manual (Yale University Press, New Haven, CT.) (1992).
8. Wun-Kim, K. et al. The DNA-binding domain of simian virus 40 tumor antigen has multiple functions. J. Virol. 67, 7608-7611 (1993).
9. Wun-Kim, K. & Simmons, D.T. Mapping of helicase and helicase substrate-binding domains on simian virus 40 large T antigen J. Virol. 64, 2014-2020 (1990).
10. Simmons, D.T., Loeber, G. & Tegtmeyer, P. Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding. J. Virol. 64, 1973-1983 (1990).
11. Simmons, D.T., Wun-Kim, K. & Young, W. Identification of simian virus 40 T-antigen residues important for specific and nonspecific binding to DNA and for helicase activity. J. Virol. 64, 4858-4865 (1990).
12. Tjian, R. The binding site on SV40 DNA for a T-antigen related protein. Cell 13, 165-179 (1978).
13. Bax, A., Ikura, M., Kay, I.E., Torchia, D.A. & Tschudin, R. Comparison of different modes of two-dimensional reverse-correlation NMR for the study of proteins J. Magn. Reson. 86, 304-318(1990).
14. Lian, L.Y., Barsukov, I.L., Sutcliffe, M.J., Sze, K.H. & Roberts, G.C.K. Protein-Ligand Interactions: Exchange Processes and Determination of Ligand Conformation and Protein-Ligand Contacts Meth. Enzym. 239, 657-700 (1994).
15. Cleland, W.W. & Kreevoy, M.M. Low-barrier hydrogen bonds and enzymatic catalysis Science 264, 1887-1890 (1994).