Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1

Toxicology and Applied Pharmacology

Volumn 282, Issue 1, 2015, Pages 52-60

  Techapiesancharoenkij, Nirachara ^a   Fiala, Jeannette L A ^b   Navasumrit, Panida ^a   Croy, Robert G ^b   Wogan, Gerald N ^b   Groopman, John D ^c   Ruchirawat, Mathuros ^a   Essigmann, John M ^b  

^a Toxicology and Management of Chemicals   (Thailand)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Aflatoxin B1; Chemoprevention; Gene expression profiling; Membrane biosynthesis; Sulforaphane

Indexed keywords

ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE CITRATE SYNTHASE; AFLATOXIN B1; APC PROTEIN; HEPCIDIN; SULFORAPHANE; TRANSFERRIN RECEPTOR; ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE; MEMBRANE LIPID; MESSENGER RNA; SULFORAFAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL GROWTH; CELL POLARITY; CELL PROLIFERATION; CELL REGENERATION; CELL SURVIVAL; CHEMOPROPHYLAXIS; CITRIC ACID CYCLE; CONTROLLED STUDY; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; GENE CONTROL; GENE EXPRESSION; GENE ONTOLOGY; GENETIC TRANSCRIPTION; GLYCOLYSIS; HYBRIDIZATION; INNATE IMMUNITY; IRON TRANSPORT; LIPID METABOLISM; LIPOGENESIS; LIVER; LIVER CELL; LIVER INJURY; LIVER TOXICITY; LIVER TUMOR; MALE; MITOSIS SPINDLE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; SIGNAL TRANSDUCTION; TISSUE REPAIR; TUMOR PROMOTION; ANIMAL; BIOSYNTHESIS; CELL MEMBRANE; CELL PROTECTION; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; LIPOLYSIS; METABOLISM; PATHOLOGY; PROCEDURES; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TIME FACTOR;

AFLATOXIN B1; ANIMALS; ANTICARCINOGENIC AGENTS; CELL MEMBRANE; CYTOPROTECTION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; ISOTHIOCYANATES; LIPOLYSIS; LIVER; MALE; MEMBRANE LIPIDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN INTERACTION MAPS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 84919904342     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.11.004     Document Type: Article

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