Proteomics analysis of the mode of antibacterial action of nanoparticles and their interactions with proteins

TrAC - Trends in Analytical Chemistry

Volumn 65, Issue , 2015, Pages 30-46

  Abdelhamid, Hani Nasser ^a,b   Wu, Hui Fen ^b,c,d,e  

^a Assiut University   (Egypt)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d SUN YAT SEN UNIVERSITY   (China)

^e NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Antibacterial action; Biocomptability; Bionanoscience; Cytotoxicity; Living cell; Mineralo protein nanoparticle; Nanoparticle; Protein corona; Proteomics; Toxicity

Indexed keywords

CELLS; CYTOLOGY; CYTOTOXICITY; MEDICAL NANOTECHNOLOGY; MOLECULAR BIOLOGY; NANOCONJUGATES; NANOPARTICLES; TOXICITY;

ANTIBACTERIAL ACTION; BIOCOMPTABILITY; BIONANOSCIENCE; LIVING CELL; PROTEIN CORONAS; PROTEIN NANOPARTICLES; PROTEOMICS;

PROTEINS;

CARBON NANOPARTICLE; COPPER OXIDE; GOLD NANOPARTICLE; MAGNETIC NANOPARTICLE; NANOPARTICLE; NICKEL NANOPARTICLE; PLATINUM NANOPARTICLE; QUANTUM DOT; SILICA NANOPARTICLE; SILVER NANOPARTICLE; TITANIUM OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; ZINC OXIDE;

ANALYTIC METHOD; ANTIBACTERIAL ACTIVITY; ATOMIC EMISSION SPECTROMETRY; ATOMIC FORCE MICROSCOPY; BODY FLUID; CHEMICAL COMPOSITION; CYTOTOXICITY; DYNAMIC LIGHT SCATTERING; ELECTRON DIFFRACTION; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; HUMAN; INCUBATION TIME; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PROTEIN INTERACTION; PROTEIN NANOPARTICLE INTERACTION; PROTEOMICS; REVIEW; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET RADIATION; X RAY DIFFRACTION; X RAY PHOTOELECTRON SPECTROSCOPY; ZETA POTENTIAL;

EID: 84919782733     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2014.09.010     Document Type: Review

References (227)

1. Coto-García A.M., Sotelo-González E., Fernández-Argüelles M.T., Pereiro R., Costa-Fernández J.M., Sanz-Medel A. Nanoparticles as fluorescent labels for optical imaging and sensing in genomics and proteomics. Anal. Bioanal. Chem 2011, 399:29-42.
2. Wu H.F., Gopal J., Abdelhamid H.N., Hasan N. Quantum dot applications endowing novelty to analytical proteomics. Proteomics 2012, 12:2949-2961.
3. Geho D.H., Jones C.D., Petricoin E.F., Liotta L.A. Nanoparticles: potential biomarker harvesters. Curr. Opin. Chem. Biol 2006, 10:56-61.
4. Ray S., Chandra H., Srivastava S. Nanotechniques in proteomics: current status, promises and challenges. Biosens. Bioelectron 2010, 25:2389-2401.
5. Li Y., Zhang X., Deng C. Functionalized magnetic nanoparticles for sample preparation in proteomics and peptidomics analysis. Chem. Soc. Rev 2013, 42:8517-8539.
6. Marko N.F., Weil R.J., Toms S.A. Nanotechnology in proteomics. Expert Rev. Proteomics 2007, 4:617-626.
7. Gonzalez-Gonzalez M., Jara-Acevedo R., Matarraz S., Jara-Acevedo M., Paradinas S., Sayagües J.M., et al. Nanotechniques in proteomics: protein microarrays and novel detection platforms. Eur. J. Pharm. Sci 2012, 499-506.
8. Agrawal G.K., Timperio A.M., Zolla L., Bansal V., Shukla R., Rakwal R. Biomarker discovery and applications for foods and beverages: proteomics to nanoproteomics. J. Proteomics 2013, 93:74-92.
9. Johnson C.J., Zhukovsky N., Cass A.E.G., Nagy J.M. Proteomics, nanotechnology and molecular diagnostics. Proteomics 2008, 8:715-730.
10. Jeong S.K., Kwon M.S., Lee E.Y., Lee H.J., Cho S.Y., Kim H., et al. Biomarkerdigger: a versatile disease proteome database and analysis platform for the identification of plasma cancer biomarkers. Proteomics 2009, 9:3729-3740.
11. Lacerda S.H., Park J.J., Meuse C., Pristinski D., Becker M.L., Karim A., et al. Interaction of gold nanoparticles with common human blood proteins. ACS Nano 2011, 4:365-379.
12. Cedervall T., Lynch I., Foy M., Berggard T., Donnelly S.C., Cagney G., et al. Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. Angew. Chem. Int. Ed Engl 2007, 46:5754-5756.
13. Hortin G.L., Sviridov D., Anderson N.L. High-abundance polypeptides of the human plasma proteome comprising the top 4 logs of polypeptide abundance. Clin. Chem 2008, 54:1608-1616.
14. Omenn G.S. Data management and data integration in the hupo plasma proteome project. Methods Mol. Biol 2011, 696:247-257.
15. Lundqvist M., Stigler J., Elia G., Lynch I., Cedervall T., Dawson K.A. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:14265-14270.
16. MacCormack T.J., Goss G.G. Identifying and predicting biological risks associated with manufactured nanoparticles in aquatic ecosystems. J. Ind. Ecol 2008, 3:286-296.
17. Lindman S., Lynch I., Thulin E., Nilsson H., Dawson K.A., Linse S. Nano Lett 2007, 7:914-920.
18. Mahmoudi M., Simchi A., Imani M., Shokrgozar M.A., Milani A.S., Hafeli U.O., et al. Colloids Surf. B. Biointerfaces 2010, 75:300-309.
19. Cedervall T., Lynch I., Lindman S., Berggard T., Thulin E., Nilsson H., et al. Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:2050-2055.
20. Mahmoudi M., Sant S., Wang B., Laurent S., Sen T. Adv. Drug Deliv. Rev 2011, 63:24.
21. Nel A.E., Madler L., Velegol D., Xia T., Hoek E.M., Somasundaran P., et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater 2009, 8:543-557.
22. Patil S., Sandberg A., Heckert E., Self W., Sudipt S. Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. Biomaterials 2007, 28:4600-4607.
23. Abdelhamid H.N., Bhaisare M.L., Wu H.F. Ceria nanocubic-ultrasonicationassisteddispersiveliquid-liquid microextraction coupled with matrix assisted laser desorption/ionization mass spectrometry for pathogenic bacteria analysis. Talanta 2014, 120:208-217.
24. Mahmoudi M., Milani A.S., Stroeve P. Synthesis, surface architecture and biological response of superparamagnetic iron oxide nanoparticles for application in drug delivery: a review. Int. J. Biomed. Nanosci. Nanotechnol 2010, 1:164-201.
25. Deb Adhikari M., Mukherjee S., Saikia J., Das G., Ramesh A. Magnetic nanoparticles for selective capture and purification of an antimicrobial peptide secreted by food-grade lactic acid bacteria. J. Mater. Chem. B 2014, 2:1432-1438.
26. Adhikari M.D., Das G., Ramesh A. Retention of nisin activity at elevated pH in an organic acid complex and gold nanoparticle composite. Chem. Commun 2012, 48:8928.
27. Leszczynski J. Bionanoscience: nano meets bio at the interface. Nat. Nanotechnol 2010, 5:633-634.
28. Adiseshaiah P.P., Hall J.B., McNeil S.E. Nanomaterial standards for efficacy and toxicity assessment. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol 2010, 2:99-112.
29. Dobrovolskaia M.A., Clogston J.D., Neun B.W., Hall B.J.B., Patri A.K., McNeil S.E. Method for analysis of nanoparticle hemolytic properties in vitro. Nano Lett 2008, 8:2180-2187.
30. Dobrovolskaia M.A., McNeil S.E. Immunological properties of engineered nanomaterials. Nat. Nanotechnol 2007, 2:469-478.
31. Lundqvist M., Stigler J., Cedervall T., Berggård T., Flanagan M.B., Lynch I., et al. The evolution of the protein corona around nanoparticles: a test study. ACS Nano 2011, 5:7503-7509.
32. Lynch I., Dawson K.A. Protein-nanoparticle interactions. Nano Today 2008, 3:40-47.
33. Karmali P.P., Simberg D. Interactions of nanoparticles with plasma proteins: implication on clearance and toxicity of drug delivery systems. Expert Opin. Drug Deliv 2011, 8:343-357.
34. Manikandan M., Abdelhamid H.N., Talib A., Wu H.F. Facile synthesis of gold nanohexagons on graphene templates in Raman spectroscopy for biosensing cancer and cancer stem cells. Biosens. Bioelectron 2014, 55:180-186.
35. Shang L., Nienhaus K., Nienhaus G.U. Engineered nanoparticles interacting with cells: size matters. J. Nanobiotechnology 2014, 12:5-11.
36. Abdelhamid H.N., Wu H.F. Polymer dots for quantifying the total hydrophobic pathogenic lysates in a single drop. Colloids Surf. B. Biointerfaces 2014, 115:51-60.
37. Capriotti A.L., Caracciolo G., Cavaliere C., Crescenzi C., Pozzi D., Laganà A. Shotgun proteomic analytical approach for studying proteins adsorbed onto liposome surface. Anal. Bioanal. Chem 2011, 401:1195-1202.
38. Gessner A., Lieske A., Paulke B.R., Müller R.H. Influence of surface charge density on protein adsorption on polymeric nanoparticles: analysis by two-dimensional electrophoresis. Eur. J. Pharm. Biopharm 2002, 54:165-170.
39. Gessner A., Lieske A., Paulke B.R., Müller R.H. Functional groups on polystyrene model nanoparticles: influence on protein adsorption. J. Biomed. Mater. Res. A 2003, 65:319-326.
40. Gessner A., Waicz R., Lieske A., Paulke B.R., Mäder K., Müller R.H. Nanoparticles with decreasing surface hydrophobicities: influence on plasma protein absorption. Int. J. Pharm 2000, 196:245-249.
41. Seehof K., Kresse M., Mäder K., Müller R.H. Interactions of nanoparticles with body proteins - improvement of 2D-Page analysis by internal standard. Int. J. Pharm 2000, 196:231-234.
42. Lück M., Paulke B.R., Schröder W., Blunk T., Müller R.H. Analysis of plasma protein adsorption on polymeric nanoparticles with different surface characteristics. J. Biomed. Mater. Res 2000, 39:478-485.
43. Müller R.H., Rühl D., Lück M., Paulke B.R. Influence of fluorescent labelling of polystyrene particles on phagocytic uptake, surface hydrophobicity, and plasma protein adsorption. Pharm. Res 1997, 14:18-24.
44. Xiao Q., Huang S., Qi Z.D., Zhou B., He Z.K., Liu Y. Conformation, thermodynamics and stoichiometry of HSA adsorbed to colloidal CdSe/ZnS quantum dots. Biochim. Biophys. Acta 2008, 1784:1020-1027.
45. Gopal J., Abdelhamid H.N., Hua P.Y., Wu H.F. Chitosan nanomagnets for effective extraction and sensitive mass spectrometric detection of pathogenic bacterial endotoxin from human urine. J. Mater. Chem. B 2013, 1:2463-2475.
46. Tenzer S., Docter D., Rosfa S., Wlodarski A., Kuharev J., Rekik A., et al. Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomics analysis. ACS Nano 2011, 5:7155-7167.
47. Brewer S.H., Glomm W.R., Johnson M.C., Knag M.K., Franzen S. Probing BSA binding to citrate-coated gold nanoparticles and surfaces S. Langmuir 2005, 21:9303-9307.
48. Deng Z.J., Liang M., Monteiro M., Toth I., Minchin R.F. Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nat. Nanotechnol 2011, 6:39-44.
49. Huang R., Carney R.P., Stellacci F., Lau B.L.T. Protein-nanoparticle interactions: the effects of surface compositional and structural heterogeneity are scale dependent. Nanoscale 2013, 5:6928-6935.
50. Goy-Lopez S., Juarez J., Alatorre-Meda M., Casals E., Puntes V.F., Taboada P., et al. Physicochemical characteristics of protein-NP bioconjugates: the role of particle curvature and solution conditions on human serum albumin conformation and fibrillogenesis inhibition. Langmuir 2012, 28:9113-9126.
51. Dobrovolskaia M.A., Neun B.W., Man S., Ye X., Hansen M., Patri A.K., et al. Protein corona composition does not accurately predict hematocompatibility of colloidal gold nanoparticles. Nanomedicine 2014, 10.1016/j.nano.2014.01.009.
52. Feliu N., Walter M.V., Montanez M.I., Kunzmann A., Hult A., Nystrom A., et al. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers. Biomaterials 2012, 33:1970-1981.
53. Hühn D., Kantner K., Geidel C., Brandholt S., De Cock I., Soenen S.J.H., et al. Polymer-coated nanoparticles interacting with proteins and cells: focusing on the sign of the net charge. ACS Nano 2013, 7:3253-3263.
54. Gebauer J.S., Malissek M., Simon S., Knauer S.K., Maskos M., Stauber R.H., et al. Impact of the nanoparticle-protein corona on colloidal stability and protein structure. Langmuir 2012, 28:9673-9679.
55. Lesniak A., Campbell A., Monopoli M.P., Lynch I., Salvati A., Dawson K.A. Serum heat inactivation affects protein corona composition and nanoparticle uptake. Biomaterials 2010, 31:9511-9518.
56. Mahmoudi M., Abdelmonem A.M., Behzadi S., Clement J.H., Dutz S., Ejtehadi M.R., et al. ACS Nano 2013, 7:6555-6562.
57. Casals E., Pfaller T., Duschl A., Oostingh G.J., Puntes V.F. Time evolution of the nanoparticle protein corona. ACS Nano 2010, 4:3623-3632.
58. Casals E., Pfaller T., Duschl A., Oostingh G.J., Puntes V.F. Hardening of the nanoparticle-protein corona in metal (Au, Ag) and oxide (Fe3O4, CoO, and CeO2) nanoparticles. Small 2011, 7:3479-3486.
59. Tenzer S., Docter D., Kuharev J., Musyanovych A., Fetz V., Hecht R., et al. Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology. Nat. Nanotechnol 2013, 8:772-781.
60. Monopoli M.P., Walczyk D., Campbell A., Elia G., Lynch I., Bombelli F.B., et al. Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. J. Am. Chem. Soc 2011, 133:2525-2534.
61. Röcker C., Pötzl M., Zhang F., Parak W.J., Nienhaus G.U. A quantitative fluorescence study of protein monolayer formation on colloidal nanoparticles. Nat. Nanotechnol 2009, 49:577-580.
62. Ehrenberg M., McGrath J.L. Binding between particles and proteins in extracts: implications for microrheology and toxicity. Acta Biomater 2005, 1:305-315.
63. Driessen M.D., Ossig R., Schnekenburger J., Vennemann A., Wiemann M., Luch A., et al. Protein carbonylation as a marker of oxidative stress induced by nanoparticles: analysis of 16 inorganic nanoparticles. Toxicol. Lett 2014, 229:S192. Abstracts of the 50th Congress of the European Societies of Toxicology (EUROTOX).
64. Adeyemi O.S., Whiteley C.G. Interaction of metal nanoparticles with recombinant arginine kinase from Trypanosoma brucei: thermodynamic and spectrofluorimetric evaluation. Biochim. Biophys. Acta 2014, 1840:701-706.
65. Xiong Z., Zhang L., Fang C., Zhang Q., Ji Y., Zhang Z., et al. Ti4+-immobilized multilayer polysaccharide coated magnetic nanoparticles for highly selective enrichment of phosphopeptides. J. Mater. Chem. B 2014, 2:4473-4480.
66. Linse S., Cabaleiro-Lago C., Xue W.F., Lynch I., Lindman S., Thulin E., et al. Nucleation of protein fibrillation by nanoparticles. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:8691-8696.
67. Aggarwal P., Hall J.B., McLeland C.B., Dobrovolskaia M.A., McNeil S.E. Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv. Drug Deliv. Rev 2009, 61:428-437.
68. Deng Z.J., Mortimer G., Schiller T., Musumeci A., Martin D., Minchin R.F. Differential plasma protein binding to metal oxide nanoparticles. Nanotechnology 2009, 20:455101.
69. Min Y.J., Akbulut M., Kristiansen K., Golan Y., Israelachvili J. The role of interparticle and external forces in nanoparticle assembly. Nat. Mater 2008, 7:527-538.
70. Treuel L., Malissek M., Gebauer J.S., Zellner R. The influence of surface composition of nanoparticles on their interactions with serum albumin. Chemphyschem 2010, 11:3093-3099.
71. Klein J. Probing the interactions of proteins and nanoparticles. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:2029-2030.
72. Wang J., Jensen U.B., Jensen G.V., Shipovskov S., Balakrishnan V.S., Otzen D., et al. Soft interactions at nanoparticles alter protein function and conformation in a size dependent manner. Nano Lett 2011, 11:4985-4991.
73. Shang W., Nuffer J.H., Muniz-Papandrea V.A., Colon W., Siegel R.W., Dordick J.S. Cytochrome c on silica nanoparticles: influence of nanoparticle size on protein structure, stability, and activity. Small 2009, 5:470-476.
74. Oh E., Delehanty J.B., Sapsford K.E., Susumu K., Goswami R., Blanco-Canosa J.B., et al. Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size. ACS Nano 2011, 5:6434-6448.
75. Cox M.C., Barnham K.J., Frenkiel T.A., Hoeschele J.D., Mason A.B., He Q.Y., et al. Identification of platination sites on human serum transferrin using (13)C and (15)N NMR spectroscopy. J. Biol. Inorg. Chem 1999, 4:621-631.
76. Marquis B.J., Maurer-Jones M.A., Braun K.L., Haynes C.L. Amperometric assessment of functional changes in nanoparticle-exposed immune cells: varying Au nanoparticle exposure time and concentration. Analyst 2009, 134:2293-2300.
77. Love S.A., Haynes C.L. Assessment of functional changes in nanoparticle-exposed neuroendocrine cells with amperometry: exploring the generalizability of nanoparticle-vesicle matrix interactions. Anal. Bioanal. Chem 2010, 398:677.
78. Maurer-Jones M.A., Lin Y.S., Haynes C.L. Functional assessment of metal oxide nanoparticle toxicity in immune cells. ACS Nano 2010, 4:3363-3373.
79. Murdock R.C., Braydich-Stolle L., Schrand A.M., Schlager J.J., Hussain S.M. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicol. Sci 2008, 101:239-253.
80. Marquis B.J., Liu Z., Braun K.L., Haynes C.L. Investigation of noble metal nanoparticle ζ-potential effects on single-cell exocytosis function in vitro with carbon-fiber microelectrode amperometry. Analyst 2011, 136:3478-3486.
81. 4 nanoparticles. Colloids Surf. B. Biointerfaces 2014, 121:354-361.
82. Ehrenberg M.S., Friedman A.E., Finkelstein J.N., Oberdorster G., McGrath J.L. The influence of protein adsorption on nanoparticle association with cultured endothelial cells. Biomaterials 2009, 30:603-610.
83. Temming K., Lacombe M., Van Der Hoeven P., Prakash J., Gonzalo T., Dijkers E.C.F., et al. Delivery of the p38 MAPkinase inhibitor SB202190 to angiogenic endothelial cells: development of novel RGD-equipped and PEGylated drug-albumin conjugates using platinum(II)-based drug linker technology. Bioconjug. Chem 2006, 17:1246-1255.
84. Gonzalo T., Talman E.G., Van De Ven A., Temming K., Greupink R., Beljaars L., et al. Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology. J. Control. Release 2006, 111:193-203.
85. Näreoja T., Määttänen A., Peltonen J., Hänninen P.E., Härmä H. Impact of surface defects and denaturation of capture surface proteins on nonspecific binding in immunoassays using antibody-coated polystyrene nanoparticle labels. J. Immunol. Methods 2009, 347:24-30.
86. Näreoja T., Vehniäinen M., Lamminmäki U., Hänninen P.E., Härmä H. Study on nonspecificity of an immuoassay using Eu-doped polystyrene nanoparticle labels. J. Immunol. Methods 2009, 345:80-89.
87. Roach P., Farrar D., Perry C.C. Interpretation of protein adsorption: surface-induced conformational changes. J. Am. Chem. Soc 2005, 127:8168-8173.
88. Kong X.L., Huang L.C.L., Hsu C.M., Chen W.H., Han C.C., Chang H.C. High-affinity capture of proteins by diamond nanoparticles for mass spectrometric analysis. Anal. Chem 2005, 77:259-265.
89. Dobrovolskaia M.A., Patri A.K., Zheng J., Clogston J.D., Ayub N., Aggarwal P., et al. Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles. Nanomedicine 2009, 5:106-117.
90. Fang C., Xiong Z., Qin H., Huang G., Liu J., Ye M., et al. One-pot synthesis of magnetic colloidal nanocrystal clusters coated with chitosan for selective enrichment of glycopeptides. Anal. Chim. Acta 2014, 841:99-105.
91. Mahmoudi M., Lynch I., Ejtehadi M.R., Monopoli M.P., Bombelli F.B., Laurent S. Protein-nanoparticle interactions: opportunities and challenges. Chem. Rev 2011, 14:5610-5637.
92. Xu Y., Wang H., Nussinov R., Ma B. Protein charge and mass contribute to the spatio-temporal dynamics of protein-protein interactions in a minimal proteome. Proteomics 2013, 13:1339-1351.
93. Zon W., Lai Y., Caruso F., Nice E.C. Emerging techniques in proteomics for probing nano-bio interactions. ACS Nano 2012, 6:10438-10448.
94. Allemann E., Gravel P., Leroux J.C., Balant L., Gurny R. J. Biomed. Mater. Res 1997, 37:229-234.
95. Blunk T., Hochstrasser D.F., Sanchez J.C., Muller B.W., Muller R.H. Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 1993, 14:1382-1387.
96. Mahmoudi M., Sardari S., Shokrgozar M.A., Laurent S., Stroeve P. Irreversible changes in protein conformation due to interaction with superparamagnetic iron oxide nanoparticles. Nanoscale 2011, 3:1127-1138.
97. Zhang H., Burnum K.E., Luna M.L., Petritis B.O., Kim J.S., Qian W.J., et al. Quantitative proteomics analysis of adsorbed plasma proteins classifies nanoparticles with different surface properties and size. Proteomics 2011, 11:4569-4577.
98. Wasdo S.C., Barber D.S., Denslow N.D., Powers K.W., Palazuelos M., Stevens S.M., et al. Differential binding of serum proteins to nanoparticles. Int. J. Nanotechnol 2008, 5:92-115.
99. Cai X., Ramalingam R., Wong H.S., Cheng J., Ajuh P., Cheng S.H., et al. Characterization of carbon nanotube protein corona by using quantitative proteomics. Nanomedicine 2013, 9:583-593.
100. Jiang X., Weise S., Hafner M., Racker C., Zhang F., Parak W.J., et al. Quantitative analysis of the protein corona on FePt nanoparticles formed by transferrin binding. J. R. Soc. Interface 2010, 7:S5-S16.
101. Kantawong F., Burgess K.E., Jayawardena K., Hart A., Burchmore R.J., Gadegaard N., et al. Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signaling. Biomaterials 2009, 30:4723-4731.
102. Pellegrino T., Kudera S., Liedl T., Javier A.M., Manna L., Parak W.J. On the development of colloidal nanoparticles towards multifunctional structures and their possible use for biological applications. Small 2005, 1:48-63.
103. Takeuchi H., Omogo B., Heyes C.D. Are bidentate ligands really better than monodentate ligands for nanoparticles?. Nano Lett 2013, 13:4746-4752.
104. MacCuspie R. Colloidal stability of silver nanoparticles in biologically relevant conditions. J. Nanopart. Res 2011, 13:2893-2908.
105. Malugin A., Ghandehari H. Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: a comparative study of rods and spheres. J. Appl. Toxicol 2010, 30:212-217.
106. Paula A.J., Silveira C., Martine D.S., Souza Filho A.G., Romero F.V., Fonseca L.C., et al. Topography-driven bionano-interactions on colloidal silica nanoparticles. ACS Appl. Mater. Interfaces 2014, 6:3437-3447.
107. Saha K., Moyano D.F., Rotello V.M. Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles. Mater. Horiz 2014, 1:102-105.
108. Suthiwangcharoen N., Li T., Wu L., Reno H.B., Thompson P., Wang Q. Facile co-assembly process to generate core-shell nanoparticles with functional protein corona. Biomacromolecules 2014, 15:948-956.
109. Walkey C.D., Olsen J.B., Song F., Liu R., Guo H., Olsen W., et al. Protein corona fingerprinting predicts the Cell Association of Gold Nanoparticles. ACS Nano 2014, 8:2439-2455.
110. Dawson K.A., Salvati A., Lynch I. Nanotoxicology: nanoparticles reconstruct lipids. Nat. Nanotechnol 2009, 4:84-85.
111. Faunce T.A., White J., MatthaeiI K.I. A nano-combinatorial library strategy for the discovery of nanotubes with reduced protein-binding, cytotoxicity, and immune response. Nanomedicine 2008, 3:859-866.
112. Capriotti A.L., Caracciolo G., Caruso G., Cavaliere C., Pozzi D., Samperi R., et al. Label-free quantitative analysis for studying the interactions between nanoparticles and plasma proteins. Anal. Bioanal. Chem 2013, 405:635-645.
113. Shang L., Wang Y., Jiang J., Dong S. pH-dependent protein conformational changes in albumin: gold nanoparticle bioconjugates: a spectroscopic study. Langmuir 2007, 23:2714-2721.
114. del Pino P., Pelaz B., Zhang Q., Maffre P., Nienhaus G.U., Parak W.J. Protein corona formation around nanoparticles - from the past to the future. Mater. Horiz 2014, 1:301-313.
115. Neal N.L. What can be inferred from bacterium-nanoparticle interactions about the potential consequences of environmental exposure to nanoparticles?. Ecotoxicology 2008, 17:362-371.
116. Saraswathy N., Ramalingam P. Introduction to Proteomics, Concepts and Techniques in Genomics and Proteomics 2011, 147-158. Chapter 10, Woodhead Publishing Limited, Cambridge, UK.
117. Petrotchenko E.V., Borchers C.H. Chapter six - modern mass spectrometry-based structural proteomics. Adv. Protein Chem. Struct. Biol 2014, 95:193-213.
118. Wu Q., Yuan H., Zhang L., Zhang Y. Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: from qualitative to quantitative analysis - a review. Anal. Chim. Acta 2012, 731:1-10.
119. Demartini D.R., Pasquali G., Carlini C.R. An overview of proteomics approaches applied to biopharmaceuticals and cyclotides research. J. Proteomics 2013, 93:224-233.
120. Zhang X., Fang A., Riley C.P., Wang M., Regnier F.E., Buck C. Multi-dimensional liquid chromatography in proteomics - a review. Anal. Chim. Acta 2010, 664:101-113.
121. Chandramouli K., Qian P.Y. Proteomics: challenges, techniques and possibilities to overcome biological sample complexity. Hum. Genomics Proteomics 2009, Article ID 239204, 22.
122. Brayner R. The toxicological impact of nanoparticles. Nano Today 2008, 3:1-2. 48-55.
123. Lara H.H., Garza-Treviño E.N., Ixtepan-Turrent L., Singh D.K. Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds. J. Nanobiotechnology 2011, 9:30.
124. Marquis B.J., Love S.A., Braun K.L., Haynes C.L. Analytical methods to assess nanoparticle toxicity. Analyst 2009, 134:425-439.
125. Sondi I., Salopek-Sondi B. Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. J. Colloid Interface Sci 2004, 275:177-182.
126. Pal S., Tak Y.K., Song J.M. Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the gram-negative bacterium Escherichia coli. Appl. Environ. Microbiol 2007, 73:1712-1720.
127. Lok C.N., Ho C.M., Chen R., He Q.Y., Yu W.Y., Sun H., et al. Silver nanoparticles: partial oxidation and antibacterial activities. J. Biol. Inorg. Chem 2007, 12:527-534.
128. Li W.R., Xie X.B., Shi Q.S., Duan S.S., Ouyang Y.S., Chen Y.B. Antibacterial effect of silver nanoparticles on Staphylococcus aureus. Biometals 2011, 24:135-141.
129. Mirzajani F., Askari H., Hamzelou S., Schober Y., Römpp A., Ghassempour A., et al. Proteomics study of silver nanoparticles toxicity on Bacillus thuringiensis. Ecotoxicol. Environ. Saf 2014, 100:122-130.
130. Tian J., Wong K.K.Y., Ho C.M., Lok C.N., Yu W.Y., Che C.M., et al. Topical delivery of silver nanoparticles promotes wound healing. ChemMedChem 2007, 2:129-136.
131. Wigginton N.S., de Titta A., Piccapietra F., Dobias J., Nesatyy V.J., Suter M.J., et al. Binding of silver nanoparticles to bacterial proteins depends on surface modifications and inhibits enzymatic activity. Environ. Sci. Technol 2010, 44:2163-2168.
132. Morones J.R., Elechiguerra J.L., Camacho A., Holt K., Kouri J.B., Ramirez J.T., et al. The bactericidal effect of silver nanoparticles. Nanotechnology 2005, 16:2346-2353.
133. Mirzajani F., Askari H., Hamzelou S., Schober Y., Römpp A., Ghassempour A., et al. Proteomics study of silver nanoparticles toxicity on Oryza sativaL. Ecotoxicol. Environ. Saf 2014, 108:335-339.
134. Hecker M., Reder A., Fuchs S., Pagels M., Engelmann S. Physiological proteomics and stress/starvation responses in Bacillus subtilis and Staphylococcus aureus. Res. Microbiol 2009, 160:245-258.
135. Miethling-Graff R., Rumpker R., Richter M., Verano-Braga T., Kjeldsen F., Brewer J., et al. Exposure to silver nanoparticles induces size- and dose-dependent oxidative stress and cytotoxicity in human colon carcinoma cells. Toxicol. In Vitro 2014, 28:1280-1289.
136. Pissuwan D., Cortie C.H., Valenzuela S.M., Cortie M.B. Functionalised gold nanoparticles for controlling pathogenic bacteria. Trends Biotechnol 2010, 28:207-213.
137. Lapresta-Fernández A., Fernández A., Blasco J. Nanoecotoxicity effects of engineered silver and gold nanoparticles in aquatic organisms. Trends Anal. Chem 2012, 32:40-59.
138. Patra C.R., Bhattacharya R., Mukhopadhyay D., Mukherjee P. Application of gold nanoparticles for targeted therapy in cancer. J. Biomed. Nanotechnol 2008, 4:99-132.
139. Tang J., Liu Y., Qi D., Yao G., Deng C., Zhang X. On-plate-selective enrichment of glycopeptides using boronic acid-modified gold nanoparticles for direct MALDI-QIT-TOF MS analysis. Proteomics 2009, 9:5046-5055.
140. Tedesco S., Doyle H., Redmond G., Sheehan D. Gold nanoparticles and oxidative stress in Mytilus edulis. Mar. Environ. Res 2008, 66:131-133.
141. Tedesco S., Doyle H., Blasco J., Redmond G., Sheehan D. Oxidative stress and toxicity of gold nanoparticles in Mytilus edulis. Aquat. Toxicol 2010, 100:178-186.
142. Tedesco S., Doyle H., Blasco J., Redmond G., Sheehan D. Exposure of the blue mussel, Mytilus edulis, to gold nanoparticles and the pro-oxidant menadione. Comp. Biochem. Physiol. C. 2010, 151:167-174.
143. Shi H., Magaye R., Castranova V., Zhao J. Titanium dioxide nanoparticles: a review of current toxicological data. Part. Fibre Toxicol 2013, 10:15-33.
144. Conde J., Larguinho M., Cordeiro A., Raposo L.R., Costa P.M., Santos S., et al. Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis. Nanotoxicology 2014, 8:521-532.
145. Guo L., Panderi I., Yan D.D., Szulak K., Li Y., Chen Y.T., et al. A comparative study of hollow copper sulfide nanoparticles and hollow gold nanospheres on degradability and toxicity. ACS Nano 2013, 7:8780-8793.
146. Gao Y., Gopee N.V., Howard P.C., Yu L.R. Proteomics analysis of early response lymph node proteins in mice treated with titanium dioxide nanoparticles. J. Proteomics 2011, 74:2745-2759.
147. Fajardo C., Sacca M.L., Martinez-Gomariz M., Costa G., Nande M., Martin M. Transcriptional and proteomic stress responses of a soil bacterium Bacillus cereus to nanosized zero-valent iron (nZVI) particles. Chemosphere 2013, 93:1077-1083.
148. 2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT cells. Part. Fibre Toxicol 2010, 7:1.
149. Chen Y.J., Chen S.H., Chien Y.Y., Chang Y.W., Liao H.K., Chang C.Y., et al. Carbohydrate-encapsulated gold nanoparticles for rapid target-protein identification and binding-epitope mapping. Chembiochem 2005, 6:1169-1173.
150. Young J.D., Martel J., Young D., Young A., Hung C.M., Young L., et al. Characterization of granulations of calcium and apatite in serum as pleomorphic mineralo-protein complexes and as precursors of putative nanobacteria. PLoS ONE 2009, 4:e5421.
151. 2 nanoparticle assisted mass spectrometry as biosensor of Staphylococcus aureus, key pathogen in nosocomial infections from air, skin surface and human nasal passage. Biosens. Bioelectron 2011, 27:201-206.
152. Ge Y., Bruno M., Wallace K., Winnik W., Prasad R.Y. Proteome profiling reveals potential toxicity and detoxification pathways following exposure of BEAS-2B cells to engineered nanoparticle titanium dioxide. Proteomics 2011, 11:2406-2422.
153. Qu Y.H., Huang Y., Lü X. Proteomics analysis of molecular biocompatibility of gold nanoparticles to human dermal fibroblasts-fetal. J. Biomed. Nanotechnol 2013, 9:40-52.
154. Arvizo R.R., Giri K., Moyano D., Miranda O.R., Madden B., McCormick D.J., et al. Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles. PLoS ONE 2012, 7:e33650.
155. Pan C.H., Liu W.T., Bien M.Y., Lin I.C., Hsiao T.C., Ma C.M., et al. Effects of size and surface of zinc oxide and aluminum-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses. Int. J. Nanomedicine 2014, 9:3631-3643.
156. Simberg D., Park J.H., Karmali P.P., Zhang W.M., Merkulov S., McCrae K., et al. Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance. Biomaterials 2009, 30:3926-3933.
157. 2 nanoparticles: application to comprehensive proteomic profiling. J. Proteome Res 2008, 7:3591-3596.
158. 2+: an exploratory biomarker discovery. Aquat. Toxicol 2014, 155:327-336.
159. Manikandan M., Wu H.F. Rapid probing the fungicidal and biological role of CdS quantum dots in Saccharomyces cereviciae and Candida utilis by MALDI-TOF MS. J. Nanopart. Res 2013, 15:1728-1740.
160. Peng C.W., Li Y. Application of quantum dots-based biotechnology in cancer diagnosis: current status and future perspectives. J. Nanomater 2010, Article ID 676839.
161. Luo G., Long J., Zhang B., Liu C., Ji S., Xu J., et al. Quantum dots in cancer therapy. Expert Opin. Drug Deliv 2012, 9:47-51.
162. Samia A.C.S., Chen X., Burda C. Semiconductor quantum dots for photodynamic therapy. J. Am. Chem. Soc 2003, 125:15736-15737.
163. Leung Y.H., Ng A.M.C., Xu X., Shen Z., Gethings L.A., Wong M.T., et al. Mechanisms of antibacterial activity of MgO: non-ROS mediated toxicity of MgO nanoparticles towardsEscherichia coli. Small 2014, 10:1171-1183.
164. Yuan J., Gao H., Ching C.B. Comparative protein profile of human hepatoma HepG2 cells treated with graphene and single-walled carbon nanotubes: an iTRAQ-coupled 2D LC-MS/MS proteome analysis. Toxicol. Lett 2011, 207:213-221.
165. Wu B.S., Abdelhamid H.N., Wu H.F. Synthesis and antibacterial activities of graphene decorated with stannous dioxide. RSC Adv 2014, 4:3722-3731.
166. Hu Z., Zhao L., Zhang H., Zhang Y., Wu R., Zou H. The on-bead digestion of protein corona on nanoparticles by trypsinimmobilized on the magnetic nanoparticle. J. Chromatogr. A 2014, 1334:55-63.
167. Larguinho M., Baptista P.V. Gold and silver nanoparticles for clinical diagnostics - from genomics to proteomics. J. Proteomics 2012, 75:2811-2823.
168. Choi O., Hu Z.Q. Size dependent and reactive oxygen species related nanosilver toxicity to nitrifying bacteria. Environ. Sci. Technol 2008, 42:4583-4588.
169. Fabrega J., Fawcett S.R., Renshaw J.C., Lead J.R. Silver nanoparticle impact on bacterial growth: effect of pH, concentration, and organic matter. Environ. Sci. Technol 2009, 43:7285-7290.
170. Lok C.N., Ho C.M., Chen R., He Q.Y., Yu W.Y., Sun H., et al. Proteomics analysis of the mode of antibacterial action of silver nanoparticles. J. Proteome Res 2006, 5:916-924.
171. Navarro E., Piccapietra F., Wagner B., Marconi F., Kaegi R., Odzak N., et al. Toxicity of silver nanoparticles to Chlamydomonas reinhardtii. Environ. Sci. Technol 2008, 42:8959-8964.
172. Lapresta-Fernández A., Fernández A., Blasco J. Nanoecotoxicity effects of engineered silver and gold nanoparticles in aquatic organisms. Trends Anal. Chem 2012, 32:40-59.
173. Rainville L.C., Carolan D., Varela A.C., Doyle H., Sheehan D. Proteomic evaluation of citrate-coated silver nanoparticles toxicity in Daphnia magna. Analyst 2014, 139:1678-1686.
174. Yuan Z., Li J., Cui L., Xu B., Zhang H., Yu C.P. Interaction of silver nanoparticles with pure nitrifying bacteria. Chemosphere 2013, 90:1404-1411.
175. Kim E., Chu Y.C., Han J.Y., Lee D.H., Kim Y.J., Kim H.C., et al. Proteomics analysis of silver nanoparticle toxicity in rat. Toxicol. Environ. Health Sci 2010, 2:251-262.
176. Verano-Braga T., Miethling-Graff R., Wojdyla K., Rogowska-Wrzesinska A., Brewer J., Erdmann H., et al. Insights into the cellular response triggered by silver nanoparticles using quantitative proteomics. ACS Nano 2014, 8:2161-2175.
177. Su C.L., Chen T.T., Chang C.C., Chuang K.J., Wu C.K., Liu W.T., et al. Comparative proteomics of inhaled silver nanoparticles in healthy and allergen provoked mice. Int. J. Nanomedicine 2013, 8:2783-2799.
178. Cui Y., Zhao Y., Tian Y., Zhang W., Lü X., Jiang X. The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli. Biomaterials 2012, 33:2327-2333.
179. Abdelhamid H.N., Wu H.F. Fuoric and Mefenamic acids as a new matrices for UV-MALDI-MS. Talanta 2013, 115:442-450.
180. Zhao Y., Tian Y., Cui Y., Liu W., Ma W., Jiang X. Small molecule-capped gold nanoparticles as potent antibacterial agents that target gram-negative bacteria. J. Am. Chem. Soc 2010, 132:12349-12356.
181. Gioria S., Chassaigne H., Carpi D., Parracino A., Meschini S., Barboro P., et al. A proteomic approach to investigate AuNPs effects in Balb/3T3 cells. Toxicol. Lett 2014, 228:111-126.
182. 2) on Mytilus hemocytes. Aquat. Toxicol 2010, 96:151-158.
183. Liu X., Ren X., Deng X., Huo Y., Xie J., Huang H., et al. A protein interaction network for the analysis of the neuronal differentiation of neural stem cells in response to titanium dioxide nanoparticles. Biomaterials 2010, 31:3063-3070.
184. 2 nanoparticles in mouse kidney. Mol. Cell. Toxicol 2010, 6:419-425.
185. Jeon Y.M., Park S.K., Lee M.Y. Proteomics analysis of hepatotoxicity induced by titanium nanoparticles in mouse liver. J. Korean Soc. Appl. Biol. Chem 2011, 54:852-859.
186. Jeon Y.M., Park S.K., Lee M.Y. Toxicoproteomic identification of TiO2 nanoparticle-induced protein expression changes in mouse brain. Animal Cells Syst. (Seoul) 2011, 15:107-114.
187. Sund J., Palomäki J., Ahonen N., Savolainen K., Alenius H., Puustinen A. Phagocytosis of nano-sized titanium dioxide triggers changes in protein acetylation. J. Proteomics 2014, 108:469-483.
188. Gedda G., Abdelhamid H.N., Khan M.S., Wu H.F. ZnO nanoparticle modified polymethyl methacrylate assisted dispersive liquid-liquid micro extraction coupled MALDI-MS for rapid pathogenic bacteria analysis. RSC Adv 2014, 4:45973-45983.
189. Madonna A.J., Cuyk S.V., Voorhees K.J. Detection of Escherichia coli using immunomagnetic separation and bacteriophage amplification coupled with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom 2003, 17:257-263.
190. Madonna A.J., Basile F., Furlong E., Voorhees K.J. Detection of bacteria from biological mixtures using immunomagnetic separation combined with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom 2001, 15:1068-1074.
191. 2 core/shell magnetic nanoparticles as photokilling agents for pathogenic bacteria. Small 2008, 4:485-491.
192. Lin Y.-S., Tsai P.-J., Weng M.-F., Chen Y.-C. Affinity capture using vancomycin-bound magnetic nanoparticles for the MALDI-MS analysis of bacteria. Anal. Chem 2005, 77:1753-1760.
193. Gao J., Li L., Ho P.L., Mak G.C., Gu H., Xu B. Combining fluorescent probes and biofunctional magnetic nanoparticles for rapid detection of bacteria in human blood. Adv. Mater 2006, 18:3145-3148.
194. Gu H.W., Ho P.L., Tsang K.W.T., Wang L., Xu B. Using biofunctional magnetic nanoparticles to capture vancomycin-resistant enterococci and other gram-positive bacteria at ultralow concentration. J. Am. Chem. Soc 2003, 125:15702-15703.
195. Gu H., Ho P.L., Tsang K.W., Yu C.W., Xu B. Using biofunctional magnetic nanoparticles to capture gram-negative bacteria at an ultra-low concentration. Chem. Commun 2003, 15:1966-1967.
196. Huang W.C., Tsai P.J., Chen Y.C. Functional gold nanoparticles as photothermal agents for selective-killing of pathogenic bacteria. Nanomedicine 2007, 2:777-787.
197. Abdelhamid H.N., Wu H.F. Multifunctional graphene magnetic nanosheet decorated with chitosan for highly sensitive detection of pathogenic bacteria. J. Mater. Chem. B 2013, 32:3950-3961.
198. Deb Adhikari M., Mukherjee S., Saikia J., Das G., Ramesh A. Magnetic nanoparticles for selective capture and purification of an antimicrobial peptide secreted by food-grade lactic acid bacteria. J. Mater. Chem. B 2014, 2:1432-1438.
199. Chen W.J., Tsai P.J., Chen Y.C. Functional nanoparticle-based proteomic strategies for characterization of pathogenic bacteria. Anal. Chem 2008, 80:9612-9621.
200. 2). J. Mater. Chem. B 2014, 2:4671-4683.
201. Okoturo-Evans O., Dybowska A., Valsami-Jones E., Cupitt J., Gierula M., Boobis A.R., et al. Elucidation of toxicity pathways in lung epithelial cells induced by silicon dioxide nanoparticles. PLoS ONE 2013, 8:e72363.
202. Jiang X., Röcker C., Hafner M., Brandholt S., Dörlich R.M., Nienhaus G.U. Endoand exocytosis of zwitterionic quantum dot nanoparticles by live HeLa cells. ACS Nano 2010, 4:6787-6797.
203. Zhao L., Liu R., Zhao X., Yang B., Gao C., Hao X., et al. New strategy for the evaluation of CdTe quantum dot toxicity targeted to bovine serum albumin. Sci. Total Environ 2009, 407:5019-5023.
204. Wang T., Bai J., Jiang X., Nienhaus G.U. Cellular uptake of nanoparticles by membrane penetration: a study combining confocal microscopy with FTIR spectroelectrochemistry. ACS Nano 2012, 6:1251-1259.
205. Verma A., Uzun O., Hu Y., Han H.S., Watson N., Chen S., et al. Surface-structure-regulated cell-membrane penetration by monolayerprotected nanoparticles. Nat. Mater 2008, 7:588-595.
206. Valizadeh A., Mikaeili H., Samiei M., Farkhani S.M., Zarghami N., Kouhi M., et al. Quantum dots: synthesis, bioapplications, and toxicity. Nanoscale Res. Lett 2012, 7:480.
207. Abdelhamid H.N., Wu H.F. Probing the interactions of chitosan capped CdS quantum dots with pathogenic bacteria and their biosensing application. J. Mater. Chem. B 2013, 1:6094-6106.
208. Zhou R., Gao H. Cytotoxicity of graphene: recent advances and future perspective. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol 2014, 10.1002/wnan.1277.
209. Price H., Arthur R., Sexton K., Gregory C., Hoogendoorn B., Matthews I., et al. Airborne particles in Swansea, UK: their collection and characterization. J. Toxicol. Environ. Health A 2010, 73:355-367.
210. Park S.K., Jeon Y.M., Son B.S., Youn H.S., Lee M.Y. Proteomics analysis of the differentially expressed proteins by airborne nanoparticles. J. Appl. Toxicol 2011, 31:463-470.
211. Triboulet S., Aude-Garcia C., Carrière M., Diemer H., Proamer F., Habert A., et al. Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses. Mol. Cell. Proteomics 2013, 12:3108-3122.
212. Gopal J., Hasan N., Manikandan M., Wu H.F. Bacterio-toxicity/compatibility of Platinum nanospheres, nanocuboids and nanoflowers. Sci. Rep 2013, 3:1260.
213. Manikandan M., Hasan N., Wu H.F. Platinum nanoparticles for photothermal treatment of neuro 2A cancer cells. Biomaterials 2013, 34:5833-5842.
214. Hasan N., Ahmad F., Wu H.F. Heat stress response of Escherichia colivia NiO nanoparticles in MALDI mass spectrometry. Talanta 2013, 103:38-46.
215. Peralta-Videa J.R., Hernandez-Viezcas J.A., Zhao L., Diaz B.C., Ge Y., Priester J.H., et al. Cerium dioxide and zinc oxide nanoparticles alter the nutritional value of soil cultivated soybean plants. Plant Physiol. Biochem 2014, 80:128-135.
216. Hondroulis E., Nelson J., Li C.Z. Biomarker analysis for nanotoxicology. Biomarkers in Toxicology 2014, 689-695. Chapter 40, Academic Press, USA.
217. Özel R.E., Liu X., Alkasir R.S.J., Andreescu S. Electrochemical methods for nanotoxicity assessment. Trends Anal. Chem 2014, 59:112-120.
218. Abdelhamid H.N., Khan M.S., Wu H.F. Graphene oxide as a nanocarrier for gramicidin (GOGD) for high antibacterial performance. RSC Adv 2014, 4:50035-50046.
219. Martel H., Young J.D. Purported nanobacteria in human blood as calcium carbonate nanoparticles. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:5549-5554.
220. Young J.D., Martel J., Young L., Wu C.Y., Young A., Young D. Putative nanobacteria represent physiological remnants and culture by-products of normal calcium homeostasis. PLoS ONE 2009, 4:e4417.
221. Wu C.Y., Martel J., Young D., Young J.D. Fetuin-A/albumin-mineral complexes resembling serum calcium granules and putative nanobacteria: demonstration of a dual inhibition-seeding concept. PLoS ONE 2009, 4:e8058.
222. Martel J., Wu C.Y., Young J.D. Critical evaluation of gamma-irradiated serum used as feeder in the culture and demonstration of putative nanobacteria and calcifying nanoparticles. PLoS ONE 2010, 5:e10343.
223. Young J.D., Martel J. The rise and fall of nanobacteria. Sci. Am 2010, 302:52-59.
224. Shiekh F.A., Charlesworth J.E., Kim S.H., Hunter L.W., Jayachandran M., Miller V.M., et al. Proteomic evaluation of biological nanoparticles isolated from human kidney stones and calcified arteries. Acta Biomater 2010, 6:4065-4072.
225. Martel J., Young D., Young A., Wu C.Y., Chen C.D., Yu J.S., et al. Comprehensive proteomics analysis of mineral nanoparticles derived from human body fluids and analyzed by liquid chromatography-tandem mass spectrometry. Anal. Biochem 2011, 418:111-125.
226. Xu J.L., Khor K.A., Sui J.J., Zhang J.H., Chen W.N. Protein expression profiles in osteoblasts in response to differentially shaped hydroxyapatite nanoparticles. Biomaterials 2009, 30:5385-5391.
227. Walczyk D., Baldelli Bombelli F., Monopoli M.P., Lynch I., Dawson K.A. What the cell ''sees'' in bionanoscience. J. Am. Chem. Soc 2010, 132:5761-5768.