Functional assessment of metal oxide nanoparticle toxicity in immune cells

ACS Nano

Volumn 4, Issue 6, 2010, Pages 3363-3373

  Maurer Jones, Melissa A ^a   Lin, Yu Shen ^a   Haynes, Christy L ^a  

^a University of Minnesota   (United States)

Author keywords

Amperometry; Mesopore; Nanotoxicity; Silica; Surface area; Surface chemistry; Titania

Indexed keywords

AMPEROMETRY; MESOPORE; NANOTOXICITY; SURFACE AREA; TITANIA;

ATOMIC EMISSION SPECTROSCOPY; ATOMIC SPECTROSCOPY; CAPILLARITY; CARBON FIBERS; CELL CULTURE; ELECTROMAGNETIC INDUCTION; GRANULATION; INDUCTIVELY COUPLED PLASMA; METALLIC COMPOUNDS; MICROELECTRODES; SILICA; SURFACE CHEMISTRY; SURFACES; TITANIUM DIOXIDE; TRANSMISSION ELECTRON MICROSCOPY;

NANOPARTICLES;

NANOMATERIAL; SILICON DIOXIDE; TITANIUM; TITANIUM DIOXIDE;

ANIMAL; ARTICLE; CELL CULTURE; CELL SURVIVAL; DRUG EFFECT; IMMUNOLOGY; MAST CELL; MATERIALS TESTING; MOUSE;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; MAST CELLS; MATERIALS TESTING; MICE; NANOSTRUCTURES; SILICON DIOXIDE; TITANIUM;

EID: 77955900751     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn9018834     Document Type: Article

References (58)

1. Maurer-Jones, M. A.; Bantz, K. C.; Love, S. A.; Marquis, B. J.; Haynes, C. L. Toxicity of Therapeutic Nanoparticles. Nanomedicine 2009, 4, 219-241.
2. Marquis, B. J.; Love, S. A.; Braun, K. L.; Haynes, C. L. Analytical Methods To Assess Nanoparticle Toxicity. Analyst 2009, 134, 425-439.
3. Lewinski, N.; Colvin, V.; Drezek, R. Cytotoxicity of Nanoparticles. Small 2008, 4, 26-49.
4. Sayes, C. M.; Reed, K. L.; Subramoney, S.; Abrams, L.; Warheit, D. B. Can In Vitro Assays Substitute for In Vivo Studies in Assessing the Pulmonary Hazards of Fine and Nanoscale Materials? J. Nanopart. Res. 2009, 11, 421-431.
5. Seagrave, J.; McDonald, J. D.; Mauderly, J. L. In Vitro versus In Vivo Exposure to Combustion Emissions. Exp. Toxicol. Pathol. 2005, 57, 233-238.
6. Fisichella, M.; Dabboue, H.; Bhattacharyya, S.; Saboungi, M.-L.; Salvetat, J.-P.; Hevor, T.; Guerin, M. Mesoporous Silica Nanoparticles Enhance MTT Formazan Exocytosis in HeLa Cells and Astrocytes. Toxicol. In Vitro 2009, 23, 697-703.
7. Monteiro-Riviere, N. A.; Inman, A. O. Challenges for Assessing Carbon Nanomaterial Toxicity to the Skin. Carbon 2006, 44, 1070-1078.
8. Low, S. P.; Williams, K. A.; Canham, L. T.; Voelcker, N. H. Evaluation of Mammalian Cell Adhesion on Surface-Modified Porous Silicon. Biomaterials 2006, 27, 4538-4546.
9. Marquis, B. J.; McFarland, A. D.; Braun, K. L.; Haynes, C. L. Dynamic Measurement of Altered Chemical Messenger Secretion after Cellular Uptake of Nanoparticles Using Carbon-Fiber Microelectrode Amperometry. Anal. Chem. 2008, 80, 3431-3437.
10. Marquis, B. J.; Maurer-Jones, M. A.; Braun, K. L.; Haynes, C. L. Amperometric Assessment of Functional Changes in Nanoparticle-Exposed Immune Cells: Varying Au Nanoparticle Exposure Time and Concentration. Analyst 2009, 134, 2293-2300.
11. Lin, R. C.; Scheller, R. H. Mechanisms of Synaptic Vesicle Exocytosis. Annu. Rev. Cell Dev. Biol. 2000, 16, 19-49.
12. Benoist, C.; Mathis, D. Mast Cells in Autoimmune Disease. Nature 2002, 420, 875-878.
13. Kovarova, M.; Rivera, J. A Molecular Understanding of Mast Cell Activation and the Promise of Anti-allergic Therapeutics. Curr. Med. Chem. 2004, 11, 2083-2091.
14. Marquis, B. J.; Haynes, C. L. The Effects of Co-culture of Fibroblasts on Mast Cell Exocytotic Release Characteristics as Evaluated by Carbon-Fiber Microelectrode Amperometry. Biophys. Chem. 2008, 137, 63-69.
15. Project on Emerging Nanotechnologies, http://nanotechproject.org/ (accessed December 2009).
16. Trewyn, B. G.; Giri, S.; Slowing, I. I.; Lin, V. S. Y. Mesoporous Silica Nanoparticle Based Controlled Release, Drug Delivery, and Biosensor Systems. Chem. Commun. 2007, 3236-3245.
17. Slowing, I. I.; Trewyn, B. G.; Giri, S.; Lin, V. S. Y. Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications. Adv. Funct. Mater 2007, 17, 1225-1236.
18. Slowing, I. I.; Vivero-Escoto, J. L.; Wu, C.-W.; Lin, V. S. Y. Mesoporous Silica Nanoparticles as Controlled Release Drug Delivery and Gene Transfection Carriers. Adv. Drug Delivery Rev. 2008, 60, 1278-1288.
19. Oberdorster, G.; Elder, A.; Rinderknecht, A. Nanoparticles and the Brain: Cause for Concern. J. Nanosci. Nanotechnol. 2009, 9, 4996-5007.
20. Warheit, D. B.; Reed, K. L.; Sayes, C. M. A Role for Nanoparticle Surface Reactivity in Facilitating Pulmonary Toxicity and Development of a Base Set of Hazard Assays as a Component of Nanoparticle Risk Management. Inhalation Toxicol. 2009, 21, 61-67.
21. Hudson, S. P.; Padera, R. F.; Langer, R.; Kohane, D. S. The Biocompatibility of Mesoporous Silicates. Biomaterials 2008, 29, 4045-4055.
22. Tao, Z.; Toms, B. B.; Goodisman, J.; Asefa, T. Mesoporosity and Functional Group Dependent Endocytosis and Cytotoxicity of Silica Nanomaterials. Chem. Res. Toxicol. 2009, 22, 1869-1880.
23. Di Pasqua, A. J.; Sharma, K. K.; Shi, Y.-L.; Toms, B. B.; Ouellette, W.; Dabrowiak, J. C.; Asefa, T. Cytotoxicity of Mesoporous Silica Nanomaterials. J. Inorg. Biochem. 2008, 102, 1416-1423.
24. Slowing, I. I.; Wu, C.-W.; Vivero-Escoto, J. L.; Lin, V. S. Y. Mesoporous Silica Nanoparticles for Reducing Hemolytic Activity towards Mammalian Red Blood Cells. Small 2009, 5, 57-62.
25. Nohynek, G. J.; Lademann, J.; Ribaud, C.; Roberts, M. S. Grey Goo on the Skin? Nanotechnology, Cosmetic and Sunscreen Safety. Crit. Rev. Toxicol. 2007, 37, 251-277.
26. Shen, X.; Zhu, L.; Liu, G.; Yu, H.; Tang, H. Enhanced Photocatalytic Degradation and Selective Removal of Nitrophenols by Using Surface Molecular Imprinted Titania. Environ. Sci. Technol. 2008, 42, 1687-1692.
27. Kormann, C.; Bahnemann, D. W.; Hoffmann, M. R. Photolysis of Chloroform and Other Organic Molecules in Aqueous Titanium Dioxide Suspensions. Environ. Sci. Technol. 1991, 25, 494-500.
28. O'Regan, B.; Graetzel, M. Low-Cost, High-Efficiency Solar Cell Based on Dye-Sensitized Colloidal Titanium Dioxide Films. Nature 1991, 353, 737-740. (Pubitemid 21912607)
29. Kuciauskas, D.; Freund, M. S.; Gray, H. B.; Winkler, J. R.; Lewis, N. S. Electron Transfer Dynamics in Nanocrystalline Titanium Dioxide Solar Cells Sensitized with Ruthenium or Osmium Polypyridyl Complexes. J. Phys. Chem. B 2001, 105, 392-403.
30. Long, T. C.; Saleh, N.; Tilton, R. D.; Lowry, G. V.; Veronesi, B. Titanium Dioxide (P25) Produces Reactive Oxygen Species in Immortalized Brain Microglia (BV2): Implications for Nanoparticle Neurotoxicity. Environ. Sci. Technol. 2006, 40, 4346-4352.
31. Heinrich, U.; Fuhst, R.; Rittinghausen, S.; Creutzenberg, O.; Bellmann, B.; Koch, W. Levsen, Chronic Inhalation Exposure of Wistar Rats and Two Different Strains of Mice to Diesel Engine Exhaust, Carbon Black, and Titanium Dioxide. Inhalation Toxicol. 1995, 7, 533-556.
32. Jin, C.-Y.; Zhu, B.-S.; Wang, X.-F.; Lu, Q.-H. Cytotoxicity of Titanium Dioxide Nanoparticles in Mouse Fibroblast Cells. Chem. Res. Toxicol. 2008, 21, 1871-1877.
33. Zhang, H.; Banfield, J. F. Thermodynamic Analysis of Phase Stability of NanocrystallineTitania. J. Mater. Chem. 1998, 8, 2073-2076.
34. Rietveld, H. M. Profile Refinement Method for Nuclear and Magnetic Structures. J. Appl. Crystallogr. 1969, 2, 65-71.
35. Everett, D. H. Basic Principles of Colloid Science; Royal Society of Chemistry: London, 1988; p 243.
36. Oberdorster, G.; Oberdorster, E.; Oberdorster, J. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles. Environ. Health Perspect. 2005, 113, 823-839.
37. Alkilany, A. M.; Nagaria, P. K.; Hexel, C. R.; Shaw, T. J.; Murphy, C. J.; Wyatt, M. D. Cellular Uptake and Cytotoxicity of Gold Nanorods: Molecular Origin of Cytotoxicity and Surface Effects. Small 2009, 5, 701-708.
38. He, X.; Nie, H.; Wang, K.; Tan, W.; Wu, X.; Zhang, P. In Vivo Study of Biodistribution and Urinary Excretion of Surface-Modified Silica Nanoparticles. Anal. Chem. 2008, 80, 9597-9603.
39. Lu, F.; Wu, S.-H.; Hung, Y.; Mou, C.-Y. Size Effect on Cell Uptake in Well-Suspended, Uniform Mesoporous Silica Nanoparticles. Small 2009, 5, 1408-1413.
40. Pan, Z.; Lee, W.; Slutsky, L.; Clark, R. A. F.; Pernodet, N.; Rafailovich, M. H. Adverse Effects of Titanium Dioxide Nanoparticles on Human Dermal Fibroblasts and How to Protect Cells. Small 2009, 5, 511-520.
41. Liu, H.-M.; Wu, S.-H.; Lu, C.-W.; Yao, M.; Hsiao, J.-K.; Hung, Y.; Lin, Y.-S.; Mou, C.-Y.; Yang, C.-S.; Huang, D.-M.; Chen, Y.-C. Mesoporous Silica Nanoparticles Improve Magnetic Labeling Efficiency in Human Stem Cells. Small 2008, 4, 619-626.
42. Tao, Z.; Morrow, M. P.; Asefa, T.; Sharma, K. K.; Duncan, C.; Anan, A.; Penefsky, H. S.; Goodisman, J.; Souid, A.-K. Mesoporous Silica Nanoparticles Inhibit Cellular Respiration. Nano Lett. 2008, 8, 1517-1526.
43. Eom, H.-J.; Choi, J. Oxidative Stress of Silica Nanoparticles in Human Bronchial Epithelial Cell, Beas-2B. Toxicol. In Vitro 2009, 23, 1326-1332.
44. Duffin, R.; Tran, L.; Brown, D.; Stone, V.; Donaldson, K. Proinflammogenic Effects of Low-Toxicity and Metal Nanoparticles In Vivo and In Vitro: Highlighting the Role of Particle Surface Area and Surface Reactivity. Inhalation Toxicol. 2007, 19, 849-856.
45. Napierska, D.; Thomassen, L. C. J.; Rabolli, V.; Lison, D.; Gonzalez, L.; Kirsch-Volders, M.; Martens, J. A.; Hoet, P. H. Size-Dependent Cytotoxicity of Monodisperse Silica Nanoparticles in Human Endothelial Cells. Small 2009, 5, 846-853.
46. Lin, Y.-S.; Haynes, C. L. Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity. J. Am. Chem. Soc. 2010, 132, 4834-4842.
47. Horie, M.; Nishio, K.; Fujita, K.; Endoh, S.; Miyauchi, A.; Saito, Y.; Iwahashi, H.; Yamamoto, K.; Murayama, H.; Nakano, H.; Nanashima, N.; Niki, E.; Yoshida, Y. Protein Adsorption of Ultrafine Metal Oxide and Its Influence on Cytotoxicity toward Cultured Cells. Chem. Res. Toxicol. 2009, 22, 543-553.
48. Theoharides, T. C.; Kempuraj, D.; Tagen, M.; Conti, P.; Kalogeromitros, D. Differential Release of Mast Cell Mediators and the Pathogenesis of Inflammation. Immunol. Rev. 2007, 217, 65-78.
49. Karlsson, H. L.; Gustafsson, J.; Cronholm, P.; Moeller, L. Size-Dependent Toxicity of Metal Oxide Particles-A Comparison between Nano-and Micrometer Size. Toxicol. Lett. 2009, 188, 112-118.
50. Fahmy, B.; Cormier, S. A. Copper Oxide Nanoparticles Induce Oxidative Stress and Cytotoxicity in Airway Epithelial Cells. Toxicol. In Vitro 2009, 23, 1365-1371.
51. 2: An In Situ Sum-Frequency Generation Study. J. Am. Chem. Soc. 2004, 126, 8094-8095.
52. 2-Anatase Surfaces by DFTCalculations: A Partial Review. Theor. Chem. Acc. 2007, 117, 663-671.
53. Zhuravlev, L. T. Concentration of Hydroxyl Groups on the Surface of Amorphous Silicas. Langmuir 1987, 3, 316-318.
54. Stober, W.; Fink, A.; Bohn, E. Controlled Growth of Monodisperse Silica Spheres in the Micron Size Range. J. Colloid Interface Sci. 1968, 26, 62-69.
55. Lin, Y.-S.; Haynes, C. L. Synthesis and Characterization of Biocompatible and Size-Tunable Multifunctional Porous Silica Nanoparticles. Chem. Mater. 2009, 21, 3979-3986.
56. Isley, S. L.; Penn, R. L. Titanium Dioxide Nanoparticles: Effect of Sol-Gel pH on Phase Composition, Particle Size, and Particle Growth Mechanism. J. Phys. Chem. C 2008, 112, 4469-4474.
57. Sayes, C. M.; Wahi, R.; Kurian, P. A.; Liu, Y. P.; West, J. L.; Ausman, K. D.; Warheit, D. B.; Colvin, V. L. Correlating Nanoscale Titania Structure with Toxicity: A Cytotoxicity and Inflammatory Response Study with Human Dermal Fibroblasts and Human Lung Epithelial Cells. Toxicol. Sci. 2006, 92, 174-185.
58. Kawagoe, K. T.; Zimmerman, J. B.; Wightman, R. M. Principles of Voltammetry and Microelectrode Surface States. J. Neurosci. Methods 1993, 48, 225-240.