Nanoparticles as fluorescent labels for optical imaging and sensing in genomics and proteomics

Analytical and Bioanalytical Chemistry

Volumn 399, Issue 1, 2011, Pages 29-42

  Coto García, Ana María ^a   Sotelo González, Emma ^a   Fernández Argüelles, María Teresa ^a   Pereiro, Rosario ^a   Costa Fernández, José M ^a   Sanz Medel, Alfredo ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

Author keywords

Bioanalysis; Genomics; Imaging; Nanoparticle; Proteomics

Indexed keywords

ANALYTICAL PERFORMANCE; BIO-IMAGING; BIOANALYSIS; BIOANALYTICAL APPLICATIONS; BIOMOLECULE DETECTION; DISEASE DIAGNOSTICS; EASE OF USE; ENVIRONMENTAL ANALYSIS; ESSENTIAL COMPONENT; FLUORESCENT LABELS; GENOMIC STUDIES; GENOMICS; GOLD NANOPARTICLES; IMAGING; MOLECULAR DETECTION; NANO-MATERIALS; OPTICAL IMAGING; OPTICAL LABELS; PROBE-BASED; PROTEOMICS; QUANTUM DOT; RARE EARTH DOPED;

BIOMOLECULES; DIAGNOSIS; NANOSTRUCTURED MATERIALS;

NANOPARTICLES;

FLUORESCENT DYE; NANOPARTICLE;

ANIMAL; CHEMISTRY; DIAGNOSTIC IMAGING; GENETIC PROCEDURES; GENOMICS; HUMAN; INSTRUMENTATION; METHODOLOGY; PROTEOMICS; REVIEW;

ANIMALS; BIOSENSING TECHNIQUES; DIAGNOSTIC IMAGING; FLUORESCENT DYES; GENOMICS; HUMANS; NANOPARTICLES; PROTEOMICS;

EID: 79451470804     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-4330-3     Document Type: Review

References (87)

1. A Waggoner 2006 Fluorescent labels for proteomics and genomics Curr Opin Chem Biol 10 62 66 1:CAS:528:DC%2BD28XhtlGntLo%3D 10.1016/j.cbpa.2006.01.005 (Pubitemid 43202289)
2. P Sharma S Brown G Walter S Santra B Moudgil 2006 Nanoparticles for bioimaging Adv Colloid Interface Sci 123 471 485 10.1016/j.cis.2006.05.026 (Pubitemid 44665822)
3. DM Willard 2003 Nanoparticles in bioanalytics Anal Bioanal Chem 376 284 286 1:CAS:528:DC%2BD3sXktVCltrY%3D
4. R Gill M Zayats I Willner 2008 Semiconductor quantum dots for bioanalysis Angew Chem Int Ed Engl 47 7602 7625 1:CAS:528:DC%2BD1cXht1GltLzK 10.1002/anie.200800169
5. RA Sperling P Rivera Gil F Zhang M Zanella WJ Parak 2008 Biological applications of gold nanoparticles Chem Soc Rev 37 1896 1908 1:CAS:528:DC%2BD1cXhtVOitb3L 10.1039/b712170a
6. CA Mirkin RL Letsinger RC Mucic JJ Storhoff 1996 A DNA-based method for rationally assembling nanoparticles into macroscopic materials Nature 382 607 609 1:CAS:528:DyaK28XltVWqsrk%3D 10.1038/382607a0 (Pubitemid 26268949)
7. TA Taton CA Mirkin RL Letsinger 2000 Scanometric DNA array detection with nanoparticle probes Science 289 8 1757 1760 1:CAS:528:DC%2BD3cXmsV2nsLo%3D 10.1126/science.289.5485.1757
8. L He MD Musick SR Nicewarner FG Salinas SJ Benkovic MJ Natan CD Keating 2000 Colloidal Au-enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization J Am Chem Soc 122 9071 9077 1:CAS:528: DC%2BD3cXmt1ChtLs%3D 10.1021/ja001215b
9. R Elghanian JJ Storhoff RC Mucic RL Letsinger CA Mirkin 1997 Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles Science 277 1078 1081 1:CAS:528:DyaK2sXlsFSisb0%3D 10.1126/science.277.5329.1078 (Pubitemid 27371624)
10. LR Hirsch JB Jackson A Lee NJ Halas JL West 2003 A whole blood immunoassay using gold nanoshells Anal Chem 75 2377 2381 1:CAS:528: DC%2BD3sXislSitro%3D 10.1021/ac0262210 (Pubitemid 36582822)
11. H Wang TB Huff DA Zweifel W He PS Low A Wei J Cheng 2005 In vitro and in vivo two-photon luminescence imaging of single gold nanorods PNAS 102 15752 15756 1:CAS:528:DC%2BD2MXht1Wru7jI 10.1073/pnas.0504892102 (Pubitemid 41552814)
12. H He C Xie J Ren 2008 Nonbleaching fluorescence of gold nanoparticles and its applications in cancer cell imaging Anal Chem 80 5951 5957 1:CAS:528:DC%2BD1cXnvFajsbw%3D 10.1021/ac8005796
13. X Wu T Ming X Wang P Wang J Wang J Chen 2010 High-photoluminescence-yield gold nanocubes: for cell imaging and photothermal therapy ACS Nano 4 113 120 1:CAS:528:DC%2BD1MXhsFKksL7L 10.1021/nn901064m
14. CJ Lin T Yang C Lee SH Huang RA Sperling M Zanella JK Li J Shen H Wang H Yeh WJ Parak WH Chang 2009 Synthesis, characterization, and bioconjugation of fluorescent gold nanoclusters toward biological labeling applications ACS Nano 3 395 401 1:CAS:528:DC%2BD1MXhtV2ltLY%3D 10.1021/nn800632j
15. M Bruchez Jr M Moronne P Gin S Weiss AP Alivisatos 1998 Semiconductor nanocrystals as fluorescent biological labels Science 281 2013 2016 1:CAS:528:DyaK1cXmtlKgurw%3D 10.1126/science.281.5385.2013 (Pubitemid 28475485)
16. WCW Chan SM Nie 1998 Quantum dot bioconjugates for ultrasensitive nonisotopic detection Science 281 2016 2018 1:CAS:528:DyaK1cXmtlKnsrk%3D 10.1126/science.281.5385.2016 (Pubitemid 28475486)
17. MK Wagner F Li J Li X Li XC Le 2010 Use of quantum dots in the development of assays for cancer biomarkers Anal Bioanal Chem 397 3213 3224 1:CAS:528:DC%2BC3cXntFSmt74%3D 10.1007/s00216-010-3847-9
18. S Am G Ruan MN Rhyner S Nie 2006 Engineering luminescent quantum dots for in vivo molecular and cellular imaging Ann Biomed Eng 34 3 14 10.1007/s10439-005-9000-9
19. C Wang X Gao X Su 2010 In vitro and in vivo imaging with quantum dots Anal Bioanal Chem 397 1397 1415 1:CAS:528:DC%2BC3cXit1amtb4%3D 10.1007/s00216-010-3481-6
20. XY Wu HJ Liu JQ Liu KN Haley JA Treadway JP Larson NF Ge F Peale MP Bruchez 2002 Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots Nat Biotechnol 21 41 46 10.1038/nbt764
21. RG Aswathy Y Yoshida T Maekawa DS Kumar 2010 Near infrared quantum dots for deep tissue imaging Anal Bioanal Chem 397 1417 1435 1:CAS:528: DC%2BC3cXjvFarsLg%3D 10.1007/s00216-010-3643-6
22. JB Delehanty CE Bradburne K Boeneman K Susumu D Farrell BC Mei JB Blanco-Canosa G Dawson PE Dawson H Mattoussi IL Medintz 2010 Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system Integr Biol 2 265 277 1:CAS:528:DC%2BC3cXovVGks7g%3D 10.1039/c0ib00002g
23. AM Smith H Duan AM Mohs S Nie 2008 Bioconjugated quantum dots for in vivo molecular and cellular imaging Adv Drug Deliv Rev 60 1226 1240 1:CAS:528:DC%2BD1cXosVOnsrw%3D 10.1016/j.addr.2008.03.015
24. H Kobayashi Y Hama Y Koyama T Barrett CAS Regino Y Urano PL Choyke 2007 Simultaneous multicolor imaging of five different lymphatic basins using quantum dots Nano Lett 7 1711 1716 1:CAS:528:DC%2BD2sXls1Oru7s%3D 10.1021/nl0707003 (Pubitemid 47140450)
25. M Hikage K Gonda M Takeda T Kamei M Kobayashi M Kumasaka M Watanabe S Satomi N Ohuchi 2010 Nano-imaging of the lymph network structure with quantum dots Nanotechnology 21 185103 10.1088/0957-4484/21/18/185103 (8pp)
26. Peng CW, Li Y (2010) Application of quantum dots-based biotechnology in cancer diagnosis: current status and future perspectives. J Nanomater 676839 (11pp)
27. ME Åkerman WCW Chan P Laakkonen SN Bhatia E Ruoslahti 2002 Nanocrystal targeting in vivo Proc Natl Acad Sci U S A 99 12617 12621 10.1073/pnas.152463399
28. B Dubertret P Skourides DJ Norris V Noireaux AH Brivanlou A Libchaber 2002 In vivo imaging of quantum dots encapsulated in phospholipid micelles Science 298 1759 1762 1:CAS:528:DC%2BD38XovFKmsr0%3D 10.1126/science.1077194 (Pubitemid 35404113)
29. X Gao Y Cui RM Levenson LWK Chung S Nie 2004 In vivo cancer targeting and imaging with semiconductor quantum dots Nat Biotechnol 22 8 969 976 1:CAS:528:DC%2BD2cXmtFWru74%3D 10.1038/nbt994 (Pubitemid 39014473)
30. L Yang H Mao YA Wang Z Cao X Peng X Wang H Duan C Ni Q Yuan G Adams MQ Smith WC Wood X Gao S Nie 2009 Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging Small 5 235 243 1:CAS:528:DC%2BD1MXhvVWlsLw%3D 10.1002/smll.200800714
31. X Yu L Chen K Li Y Li S Luo J Liu L Deng D Pang Wang 2007 Immunofluorescence detection with quantum dot bioconjugates for hepatoma in vivo J Biomed Opt 12 014008 10.1117/1.2437744 (Pubitemid 46681960)
32. J Liu SK Lau VA Varma RA Moffitt M Caldwell T Liu AN Young JA Petros AO Osunkoya T Krogstad B Leyland-Jones MD Wang S Nie 2010 Molecular mapping of tumor heterogeneity on clinical tissue specimens with multiplexed quantum dots ACS Nano 4 2755 2765 1:CAS:528:DC%2BC3cXksVKltLc%3D 10.1021/nn100213v
33. M Kuno DP Fromm HF Hamann A Gallagher DJ Nesbitt 2000 Hydrolysis of sulfur trioxide to form sulfuric acid in small water clusters J Chem Phys 112 3117 3120 1:CAS:528:DC%2BD3cXptFWlsA%3D%3D 10.1063/1.480896
34. DK Chatterjee AJ Rufaihah Y Zhang 2008 Upconversion fluorescence imaging of cells and small animals using lanthanide doped nanocrystals Biomaterials 29 937 943 1:CAS:528:DC%2BD2sXhsVGltbjL 10.1016/j.biomaterials.2007.10.051 (Pubitemid 350266053)
35. H Wang T Nann 2009 Monodisperse upconverting nanocrystals by microwave-assisted synthesis ACS Nano 3 3804 3808 1:CAS:528:DC%2BD1MXhtlaltb3O 10.1021/nn9012093
36. H Kobayashi N Kosaka M Ogawa NY Morgan PD Smith CB Murray X Ye J Collins GA Kumar H Belld PL Choyke 2009 In vivo multiple color lymphatic imaging using upconverting nanocrystals J Mater Chem 19 6481 6484 1:CAS:528: DC%2BD1MXhtVOmsr%2FL 10.1039/b910512c
37. Hilderbrand SA, Shao F, Salthouse C, Mahmoodb U, Weissleder R (2009) Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commum 4188-4190
38. B Ungun RK Prud'homme SJ Budijono J Shan SF Lim Y Ju R Austin 2009 Nanofabricated upconversion nanoparticles for photodynamic therapy Opt Express 17 80 86 1:CAS:528:DC%2BD1MXpsVOgsw%3D%3D 10.1364/OE.17.000080
39. Z Chen H Che H Hu M Yu F Li Q Zhang Z Zhou T Yi C Huang 2008 Versatile synthesis strategy for carboxylic acid functionalized with upconverting nanophosphors as biological labels J Am Chem Soc 130 3023 3029 1:CAS:528:DC%2BD1cXitVamt7w%3D 10.1021/ja076151k (Pubitemid 351455973)
40. Y Sun B Zhou Y Lin W Wang KAS Fernando P Pathak MJ Meziani BA Harruff X Wang H Wang PG Luo H Yang ME Kose B Chen LM Veca S Xie 2006 Quantum-sized carbon dots for bright and colorful photoluminescence J Am Chem Soc 128 7756 7757 1:CAS:528:DC%2BD28XkvVehur0%3D 10.1021/ja062677d (Pubitemid 43945716)
41. L Cao X Wang MJ Meziani F Lu H Wang PG Luo Y Lin BA Harruff LM Veca D Murria S Xie Y Sun 2007 Carbon dots for multiphoton bioimaging J Am Chem Soc 129 11318 11319 1:CAS:528:DC%2BD2sXpsFCjtb8%3D 10.1021/ja073527l (Pubitemid 47555535)
42. S Yang X Wang H Wang F Lu PG Luo L Cao MJ Meziani J Liu Y Liu M Chen Y Huang Y Sun 2009 Carbon dots as nontoxic and high-performance fluorescence imaging agents J Phys Chem C 113 18110 18114 1:CAS:528:DC%2BD1MXhtFynsbbE 10.1021/jp9085969
43. S Yang L Cao PG Luo F Lu X Wang H Wang MJ Meziani Y Liu G Qi Y Sun 2007 Carbon dots for optical imaging in vivo J Am Chem Soc 131 11308 11309 10.1021/ja904843x
44. L Li J Song S Li C Fan 2009 Biomolecular sensing via coupling DNA-based recognition with gold nanoparticles J Phys D Appl Phys 42 203001 203012 10.1088/0022-3727/42/20/203001
45. W Wang C Chen M Qian X Zhao 2008 Aptamer biosensor using gold nanoparticles Anal Bioanal Chem 373 213 219 1:CAS:528:DC%2BD1cXivVGntg%3D%3D
46. CC Huang K Chiang ZH Lin KH Lee HT Chang 2008 Bioconjugated gold nanodots and nanoparticles for protein assays based on photoluminescence quenching Anal Chem 80 1497 1504 1:CAS:528:DC%2BD1cXht1Cjtr0%3D 10.1021/ac701998f (Pubitemid 351429552)
47. IL Mendintz H Mattoussi 2009 Quantum dot-based resonance energy transfer and its growing appliaction in biology Phys Chem Chem Phys 11 17 45 10.1039/b813919a
48. IL Medintz AR Clapp H Mattoussi ER Goldman B Fisher JM Mauro 2003 Self-assembled nanoscale biosensors based on quantum dot FRET donors Nat Mater 2 630 638 1:CAS:528:DC%2BD3sXmvVCrsLk%3D 10.1038/nmat961
49. H Dong W Gao F Yan H Ji H Ju 2010 Fluorescence resonance energy transfer between quantum dots and graphene oxide for sensing biomolecules Anal Chem 82 5511 5517 1:CAS:528:DC%2BC3cXntVSjtL8%3D 10.1021/ac100852z
50. IL Medintz AR Clapp FM Brunel T Tiefenbrunn HT Uyeda EL Chang JR Deschamps PE Dawson H Mattoussi 2006 Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates Nat Mater 5 581 589 1:CAS:528:DC%2BD28XmsVGjtr8%3D 10.1038/nmat1676 (Pubitemid 43993080)
51. M Suzuki Y Husimi H Komatsu K Suzuki KT Douglas 2008 Quantum dot FRET biosensors that respond to pH, to proteolytic or nucleolytic cleavage, to DNA synthesis, or to a multiplexing combination J Am Chem Soc 130 5720 5725 1:CAS:528:DC%2BD1cXktlCiu7k%3D 10.1021/ja710870e (Pubitemid 351600504)
52. D Geissler LJ Charbonniere RF Ziessel NG Butlin H-G Löhmannsrö ben N Hildebrandt 2010 Quantum dot biosensors for ultrasensitive multiplexed diagnostics Angew Chem Int Ed Engl 49 1396 1401 1:CAS:528:DC%2BC3cXitVWjsbg%3D
53. C-Y Zhang H-C Yeh MT Kuroki T Wang 2005 Single quantum dot-based DNA nanosensor Nat Mater 4 826 831 10.1038/nmat1508
54. Price CP, Newman DJ (1997) Principles and practice of immunoassay. Stockton, New York
55. CP Soman TD Giorgio 2008 Quantum dot self-assembly for protein detection with sub-picomolar sensitivity Langmuir 24 4399 4404 1:CAS:528: DC%2BD1cXjtVCqsro%3D 10.1021/la704078u (Pubitemid 351569058)
56. ER Goldman AR Clapp GP Anderson HT Uyeda JM Mauro IL Medintz H Mattoussi 2004 Multiplexed toxin analysis using four colors of quantum dot fluororeagents Anal Chem 76 684 688 1:CAS:528:DC%2BD3sXpvFKhsbk%3D 10.1021/ac035083r (Pubitemid 38166574)
57. LJ Yang YB Li 2006 Simultaneous detection of Escherichia coli O157:H7 and Salmonella Typhimurium using quantum dots as fluorescence labels Analyst 131 394 401 1:CAS:528:DC%2BD28Xhs12nsLk%3D 10.1039/b510888h
58. Q Wei M Lee X Yu EK Lee GH Seong J Choo YW Cho 2006 Development of an open sandwich fluoroimmunoassay based on fluorescence resonance energy transfer Anal Biochem 358 31 37 1:CAS:528:DC%2BD28XhtVykt77I 10.1016/j.ab.2006.08.019 (Pubitemid 44511908)
59. Z Wang R Levy DG Fernig M Mathias Brust 2006 Kinase-catalyzed modification of gold nanoparticles: a new approach to colorimetric kinase activity screening J Am Chem Soc 128 2214 2215 1:CAS:528:DC%2BD28Xoslagtg%3D%3D 10.1021/ja058135y
60. Y Choi N-H Ho C-H Tung 2007 Sensing phosphatase activity by using gold nanoparticles Angew Chem Int Ed Engl 46 707 709 1:CAS:528:DC%2BD2sXhtlekt7c%3D 10.1002/anie.200603735 (Pubitemid 46155394)
61. Zhao W, Chiuman W, Lam JCF, Brook MA, Li Y (2007) Simple and rapid colorimetric enzyme sensing assays using non-crosslinking gold nanoparticle aggregation. Chem Commun 3729-3731 (Pubitemid 47404166)
62. I Maier MRA Morgan W Lindner F Pittner 2008 Optical resonance-enhanced absorption-based near-field immunochip biosensor for allergen detection Anal Chem 80 2694 2703 1:CAS:528:DC%2BD1cXjsFGisro%3D 10.1021/ac702107k (Pubitemid 351556429)
63. WR Algar UJ Krull 2007 Towards multi-colour strategies for the detection of oligonucleotide hybridization using quantum dots as energy donors in fluorescence resonance energy transfer (FRET) Anal Chim Acta 581 193 201 1:CAS:528:DC%2BD28Xhtlals7vP 10.1016/j.aca.2006.08.026 (Pubitemid 44838460)
64. PS Eastman WM Ruan M Doctolero R Nuttall GD Feo JS Park JFS Chu P Cooke JW Gray S Li FQF Chen 2006 Qdot nanobarcodes for multiplexed gene expression analysis Nano Lett 6 1059 1064 1:CAS:528:DC%2BD28XjslSlurg%3D 10.1021/nl060795t (Pubitemid 43836628)
65. S Tombelli M Minunni M Mascini 2007 Aptamers-based assays for diagnostics, environmental and food analysis Biomol Eng 24 191 200 1:CAS:528:DC%2BD2sXls1SjsLs%3D 10.1016/j.bioeng.2007.03.003 (Pubitemid 46755014)
66. G Wang Y Wang L Chen J Choo 2010 Nanomaterials-assisted aptamers for optical sensing Biosens Bioelectron 25 1859 1868 1:CAS:528:DC%2BC3cXjtVCqtLo%3D 10.1016/j.bios.2009.11.012
67. M De PS Ghosh VM Rotello 2008 Applications of nanoparticles in biology Adv Mater 20 4225 4241 1:CAS:528:DC%2BD1cXhsVOhu73O 10.1002/adma.200703183
68. T Mairal VC Özalp P Lozano-Sánchez M Mir I Katakis CK O'Sullivan 2008 Aptamers: molecular tools for analytical applications Anal Bioanal Chem 390 989 1007 1:CAS:528:DC%2BD1cXhsFamtLo%3D 10.1007/s00216-007- 1346-4 (Pubitemid 351207799)
69. MS Han AKR Lytton-Jean BK Oh J Heo CA Mirkin 2006 Colorimetric screening of DNA-binding molecules with gold nanoparticles probes Angew Chem Int Ed Engl 45 1807 1810 1:CAS:528:DC%2BD28XislSls74%3D 10.1002/anie.200504277 (Pubitemid 44105261)
70. V Pavlov Y Xiao B Shlyahovsky I Willner 2004 Aptamer-functionalized Au nanoparticles for the amplified optical detection of thrombin J Am Chem Soc 126 11768 11769 1:CAS:528:DC%2BD2cXnt1eht7c%3D 10.1021/ja046970u (Pubitemid 39298307)
71. RC Becker FA Spencer 1998 Thrombin: structure, biochemistry, measurement, and status in clinical medicine J Thromb Thrombolys 5 215 229 1:CAS:528:DyaK1cXktFeks70%3D 10.1023/A:1008843925851 (Pubitemid 28241448)
72. NR Jana JY Ying 2008 Synthesis of functionalized Au nanoparticles for protein detection Adv Mater 20 430 434 1:CAS:528:DC%2BD1cXlt1Wnt74%3D 10.1002/adma.200701348
73. SJ Zhen CZ Huang J Wang YF Li 2009 End-to-end assembly of gold nanorods on the basis of aptamer-protein J Phys Chem C 113 21543 21547 1:CAS:528:DC%2BD1MXhsFekt7nL 10.1021/jp905084e
74. CC Huang YF Huang Z Cao W Tan HT Chang 2005 Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors Anal Chem 77 5735 5741 1:CAS:528:DC%2BD2MXntVOksbw%3D 10.1021/ac050957q (Pubitemid 41266072)
75. ZS Wu HX Lu XP Liu R Hu H Zhou G Shen RQ Yu 2010 An inhibitory effect of target binding on hairpin aptamer sticky-end pairing-induced gold nanoparticles assembly for light-up colorimetric protein assay Anal Chem 82 3890 3898 1:CAS:528:DC%2BC3cXkslKks7k%3D 10.1021/ac100422h
76. CD Medley JE Smith Z Tang Y Wu S Bamrungsap W Tan 2008 Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells Anal Chem 80 1067 1072 1:CAS:528:DC%2BD1cXmtlersg%3D%3D 10.1021/ac702037y (Pubitemid 351272339)
77. J Zhang L Wang H Zhang F Boey S Song C Fan 2010 Aptamer-based multicolour fluorescent gold nanoprobes for multiplex detection in homogeneous solution Small 6 201 204 1:CAS:528:DC%2BC3cXosF2gug%3D%3D 10.1002/smll.200901012
78. M Levi SF Cater AD Ellington 2005 Quantum-dot aptamer beacons for the detection of proteins Chembiochem 6 2163 2166 10.1002/cbic.200500218
79. AKH Cheng H Su YA Wang HZ Yu 2009 Aptamer-based detection of epithelial tumor marker Mucin 1 with quantum dot-based fluorescence readout Anal Chem 81 6130 6139 1:CAS:528:DC%2BD1MXotVGlsr4%3D 10.1021/ac901223q
80. Dyakyusha L, Yin H, Jaiswal S, Brown T, Baumberg JJ, Booy FP, Melvin T (2005) Quenching of CdSe quantum dot emission, a new approach for biosensing. Chem Commun 3201-3203
81. E Oh MY Hong D Lee SH Nam HC Yoon HS Kim 2005 Inhibition assay of biomolecules based on fluorescence resonance energy transfer (FRET) between quantum dots and gold nanoparticles J Am Chem Soc 127 3270 3271 1:CAS:528:DC%2BD2MXhsFCgur8%3D 10.1021/ja0433323 (Pubitemid 40365254)
82. E Oh D Lee YP Kim SY Cha DB Oh HA Kang J Kim HS Kim 2006 Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation Angew Chem Int Ed Engl 45 7959 7963 1:CAS:528:DC%2BD28XhtlektrjM 10.1002/anie.200601948 (Pubitemid 44912751)
83. D Gerion F Chen B Kannan A Fu WJ Parak DJ Chen A Majumdar AP Alivisatos 2003 Room-temperature single-nucleotide polymorphism and multiallele DNA detection using fluorescent nanocrystals and microarrays Anal Chem 75 4766 4772 1:CAS:528:DC%2BD3sXmsVyqtLw%3D 10.1021/ac034482j (Pubitemid 37139776)
84. JH Kim S Chaudhary M Ozkan 2007 Multicolour hybrid nanoprobes of molecular beacon conjugated quantum dots: FRET and gel electrophoresis assisted target DNA detection Nanotechnology 18 195105 10.1088/0957-4484/18/19/195105 (Pubitemid 46786428)
85. CY Zhang LW Johnson 2006 Quantum-dot-based nanosensor for RRE IIB RNA-Rev peptide interaction assay J Am Chem Soc 128 5324 5325 1:CAS:528: DC%2BD28XivF2qt78%3D 10.1021/ja060537y
86. Fernandez-Argüelles MT, Costa Fernández JM, Pereiro R, Sanz Medel A (2010) Chap. 12, The supramolecular chemistry of organic-inorganic hybrid materials, John Wiley & Sons, Inc
87. Rurack K, Martínez-Mañez R (2010) Chap. 12, The supramolecular chemistry of organic-inorganic hybrid materials, John Wiley & Sons, Inc., New Jersey