메뉴 건너뛰기




Volumn 28, Issue 5, 2014, Pages 685-701

Hypothalamic control of adipose tissue

Author keywords

brite beige fat; brown adipose tissue; hypothalamus; sympathetic nervous system; white adipose tissue

Indexed keywords

FAT;

EID: 84919770204     PISSN: 1521690X     EISSN: 15321908     Source Type: Journal    
DOI: 10.1016/j.beem.2014.08.001     Document Type: Review
Times cited : (19)

References (102)
  • 1
    • 0031843809 scopus 로고    scopus 로고
    • Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue
    • M. Bamshad, V.T. Aoki, and M.G. Adkison Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue Am J Physiol 275 1 Pt 2 1998 R291 R299
    • (1998) Am J Physiol , vol.275 , Issue.1 , pp. R291-R299
    • Bamshad, M.1    Aoki, V.T.2    Adkison, M.G.3
  • 2
    • 0033036199 scopus 로고    scopus 로고
    • CNS origins of the sympathetic nervous system outflow to brown adipose tissue
    • M. Bamshad, C.K. Song, and T.J. Bartness CNS origins of the sympathetic nervous system outflow to brown adipose tissue Am J Physiol 276 6 Pt 2 1999 R1569 R1578
    • (1999) Am J Physiol , vol.276 , Issue.6 , pp. R1569-R1578
    • Bamshad, M.1    Song, C.K.2    Bartness, T.J.3
  • 3
    • 0013837158 scopus 로고
    • Studies on the metabolism of adipose tissue. 18. in vitro effects of insulin, epinephrine and glucagon on lipolysis and glycolysis in pigeon adipose tissue
    • A.G. Goodridge, and E.G. Ball Studies on the metabolism of adipose tissue. 18. In vitro effects of insulin, epinephrine and glucagon on lipolysis and glycolysis in pigeon adipose tissue Comp Biochem Physiol 16 4 1965 367 381
    • (1965) Comp Biochem Physiol , vol.16 , Issue.4 , pp. 367-381
    • Goodridge, A.G.1    Ball, E.G.2
  • 4
    • 0015225772 scopus 로고
    • Effects of glucagon, epinephrine and insulin on in vitro lipolysis of adipose tissue from mammals and birds
    • W.F. Prigge, and F. Grande Effects of glucagon, epinephrine and insulin on in vitro lipolysis of adipose tissue from mammals and birds Comp Biochem Physiol B 39 1 1971 69 82
    • (1971) Comp Biochem Physiol B , vol.39 , Issue.1 , pp. 69-82
    • Prigge, W.F.1    Grande, F.2
  • 5
    • 0014601943 scopus 로고
    • Criteria for differentiation of brown and white fat in the rat
    • H. Daniel, and D.M. Derry Criteria for differentiation of brown and white fat in the rat Can J Physiol Pharmacol 47 11 1969 941 945
    • (1969) Can J Physiol Pharmacol , vol.47 , Issue.11 , pp. 941-945
    • Daniel, H.1    Derry, D.M.2
  • 6
    • 0017856171 scopus 로고
    • Morphological studies on the adrenergic innervation of white adipose tissue
    • B.G. Slavin, and K.W. Ballard Morphological studies on the adrenergic innervation of white adipose tissue Anat Rec 191 3 1978 377 389
    • (1978) Anat Rec , vol.191 , Issue.3 , pp. 377-389
    • Slavin, B.G.1    Ballard, K.W.2
  • 7
    • 0028951399 scopus 로고
    • Catecholaminergic innervation of white adipose tissue in Siberian hamsters
    • T.G. Youngstrom, and T.J. Bartness Catecholaminergic innervation of white adipose tissue in Siberian hamsters Am J Physiol 268 3 Pt 2 1995 R744 R751
    • (1995) Am J Physiol , vol.268 , Issue.3 , pp. R744-R751
    • Youngstrom, T.G.1    Bartness, T.J.2
  • 8
    • 0026099051 scopus 로고
    • Neural control of brown adipose tissue thermogenesis, hypertrophy, and atrophy
    • J. Himms-Hagen Neural control of brown adipose tissue thermogenesis, hypertrophy, and atrophy Front Neuroendocrinol 12 1991 38 93
    • (1991) Front Neuroendocrinol , vol.12 , pp. 38-93
    • Himms-Hagen, J.1
  • 9
    • 33646695720 scopus 로고    scopus 로고
    • Innervation of brown adipose tissue and its role in thermogenesis
    • T.J. Bartness, and C.K. Song Innervation of brown adipose tissue and its role in thermogenesis Can J Diabetes 29 4 2005 420 428
    • (2005) Can J Diabetes , vol.29 , Issue.4 , pp. 420-428
    • Bartness, T.J.1    Song, C.K.2
  • 10
    • 82555186955 scopus 로고    scopus 로고
    • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
    • K.D. Nguyen, Y. Qiu, and X. Cui Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis Nature 480 7375 2011 104 108
    • (2011) Nature , vol.480 , Issue.7375 , pp. 104-108
    • Nguyen, K.D.1    Qiu, Y.2    Cui, X.3
  • 11
    • 84873518501 scopus 로고    scopus 로고
    • Adaptive thermogenesis in adipocytes: Is beige the new brown?
    • J. Wu, P. Cohen, and B.M. Spiegelman Adaptive thermogenesis in adipocytes: is beige the new brown? Genes Dev 27 3 2013 234 250
    • (2013) Genes Dev , vol.27 , Issue.3 , pp. 234-250
    • Wu, J.1    Cohen, P.2    Spiegelman, B.M.3
  • 12
    • 77950237717 scopus 로고    scopus 로고
    • The changed metabolic world with human brown adipose tissue: Therapeutic visions
    • J. Nedergaard, and B. Cannon The changed metabolic world with human brown adipose tissue: therapeutic visions Cell Metab 11 4 2010 268 272
    • (2010) Cell Metab , vol.11 , Issue.4 , pp. 268-272
    • Nedergaard, J.1    Cannon, B.2
  • 13
    • 84887431711 scopus 로고    scopus 로고
    • Brown and beige fat: Development, function and therapeutic potential
    • M. Harms, and P. Seale Brown and beige fat: development, function and therapeutic potential Nat Med 19 10 2013 1252 1263
    • (2013) Nat Med , vol.19 , Issue.10 , pp. 1252-1263
    • Harms, M.1    Seale, P.2
  • 14
    • 84865142899 scopus 로고    scopus 로고
    • A new, powerful player in lipoprotein metabolism: Brown adipose tissue
    • A. Bartelt, M. Merkel, and J. Heeren A new, powerful player in lipoprotein metabolism: brown adipose tissue J Mol Med (Berl) 90 8 2012 887 893
    • (2012) J Mol Med (Berl) , vol.90 , Issue.8 , pp. 887-893
    • Bartelt, A.1    Merkel, M.2    Heeren, J.3
  • 15
    • 84864287504 scopus 로고    scopus 로고
    • Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
    • J. Wu, P. Bostrom, and L.M. Sparks Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human Cell 150 2 2012 366 376
    • (2012) Cell , vol.150 , Issue.2 , pp. 366-376
    • Wu, J.1    Bostrom, P.2    Sparks, L.M.3
  • 16
    • 78650945931 scopus 로고    scopus 로고
    • Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
    • P. Seale, H.M. Conroe, and J. Estall Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice J Clin Invest 121 1 2011 96 105
    • (2011) J Clin Invest , vol.121 , Issue.1 , pp. 96-105
    • Seale, P.1    Conroe, H.M.2    Estall, J.3
  • 17
    • 84877329765 scopus 로고    scopus 로고
    • How brown is brown fat? It depends where you look
    • J. Nedergaard, and B. Cannon How brown is brown fat? it depends where you look Nat Med 19 5 2013 540 541
    • (2013) Nat Med , vol.19 , Issue.5 , pp. 540-541
    • Nedergaard, J.1    Cannon, B.2
  • 18
    • 84877263632 scopus 로고    scopus 로고
    • A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans
    • N.Z. Jespersen, T.J. Larsen, and L. Peijs A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans Cell Metab 17 5 2013 798 805
    • (2013) Cell Metab , vol.17 , Issue.5 , pp. 798-805
    • Jespersen, N.Z.1    Larsen, T.J.2    Peijs, L.3
  • 19
    • 84877340732 scopus 로고    scopus 로고
    • Evidence for two types of brown adipose tissue in humans
    • M.E. Lidell, M.J. Betz, and O. Dahlqvist Leinhard Evidence for two types of brown adipose tissue in humans Nat Med 19 5 2013 631 634
    • (2013) Nat Med , vol.19 , Issue.5 , pp. 631-634
    • Lidell, M.E.1    Betz, M.J.2    Dahlqvist Leinhard, O.3
  • 20
    • 84878525220 scopus 로고    scopus 로고
    • Bi-directional interconversion of brite and white adipocytes
    • M. Rosenwald, A. Perdikari, and T. Rulicke Bi-directional interconversion of brite and white adipocytes Nat Cell Biol 15 6 2013 659 667
    • (2013) Nat Cell Biol , vol.15 , Issue.6 , pp. 659-667
    • Rosenwald, M.1    Perdikari, A.2    Rulicke, T.3
  • 21
    • 77950226740 scopus 로고    scopus 로고
    • Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
    • N. Petrovic, T.B. Walden, and I.G. Shabalina Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes J Biol Chem 285 10 2010 7153 7164
    • (2010) J Biol Chem , vol.285 , Issue.10 , pp. 7153-7164
    • Petrovic, N.1    Walden, T.B.2    Shabalina, I.G.3
  • 22
    • 84872066769 scopus 로고    scopus 로고
    • Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots
    • K. Karastergiou, S.K. Fried, and H. Xie Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots J Clin Endocrinol Metab 98 1 2013 362 371
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.1 , pp. 362-371
    • Karastergiou, K.1    Fried, S.K.2    Xie, H.3
  • 23
    • 33745804103 scopus 로고    scopus 로고
    • Is visceral fat involved in the pathogenesis of the metabolic syndrome? Human model
    • M.D. Jensen Is visceral fat involved in the pathogenesis of the metabolic syndrome? Human model Obes (Silver Spring) 14 Suppl. 1 2006 20S 24S
    • (2006) Obes (Silver Spring) , vol.14 , pp. 20S-24S
    • Jensen, M.D.1
  • 24
    • 4544369644 scopus 로고    scopus 로고
    • Regional adiposity and insulin resistance
    • A. Garg Regional adiposity and insulin resistance J Clin Endocrinol Metab 89 9 2004 4206 4210
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.9 , pp. 4206-4210
    • Garg, A.1
  • 25
    • 85027909934 scopus 로고    scopus 로고
    • Adipose tissue browning and metabolic health
    • A. Bartelt, and J. Heeren Adipose tissue browning and metabolic health Nat Rev Endocrinol 10 1 2014 24 36
    • (2014) Nat Rev Endocrinol , vol.10 , Issue.1 , pp. 24-36
    • Bartelt, A.1    Heeren, J.2
  • 26
    • 34547631960 scopus 로고    scopus 로고
    • Unexpected evidence for active brown adipose tissue in adult humans
    • J. Nedergaard, T. Bengtsson, and B. Cannon Unexpected evidence for active brown adipose tissue in adult humans Am J Physiol Endocrinol Metab 293 2 2007 E444 E452
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , Issue.2 , pp. E444-E452
    • Nedergaard, J.1    Bengtsson, T.2    Cannon, B.3
  • 27
    • 67650242165 scopus 로고    scopus 로고
    • High incidence of metabolically active brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
    • M. Saito, Y. Okamatsu-Ogura, and M. Matsushita High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity Diabetes 58 7 2009 1526 1531
    • (2009) Diabetes , vol.58 , Issue.7 , pp. 1526-1531
    • Saito, M.1    Okamatsu-Ogura, Y.2    Matsushita, M.3
  • 29
    • 64349123664 scopus 로고    scopus 로고
    • Functional brown adipose tissue in healthy adults
    • K.A. Virtanen, M.E. Lidell, and J. Orava Functional brown adipose tissue in healthy adults N Engl J Med 360 15 2009 1518 1525
    • (2009) N Engl J Med , vol.360 , Issue.15 , pp. 1518-1525
    • Virtanen, K.A.1    Lidell, M.E.2    Orava, J.3
  • 30
    • 64349105205 scopus 로고    scopus 로고
    • Identification and importance of brown adipose tissue in adult humans
    • A.M. Cypess, S. Lehman, and G. Williams Identification and importance of brown adipose tissue in adult humans N Engl J Med 360 15 2009 1509 1517
    • (2009) N Engl J Med , vol.360 , Issue.15 , pp. 1509-1517
    • Cypess, A.M.1    Lehman, S.2    Williams, G.3
  • 31
    • 4143078238 scopus 로고    scopus 로고
    • The brown adipocyte: Update on its metabolic role
    • H. Sell, Y. Deshaies, and D. Richard The brown adipocyte: update on its metabolic role Int J Biochem Cell Biol 36 11 2004 2098 2104
    • (2004) Int J Biochem Cell Biol , vol.36 , Issue.11 , pp. 2098-2104
    • Sell, H.1    Deshaies, Y.2    Richard, D.3
  • 32
    • 0034611678 scopus 로고    scopus 로고
    • Towards a molecular understanding of adaptive thermogenesis
    • B.B. Lowell, and B.M. Spiegelman Towards a molecular understanding of adaptive thermogenesis Nature 404 6778 2000 652 660
    • (2000) Nature , vol.404 , Issue.6778 , pp. 652-660
    • Lowell, B.B.1    Spiegelman, B.M.2
  • 33
    • 0031771002 scopus 로고    scopus 로고
    • Brown adipose tissue. More than an effector of thermogenesis?
    • B. Cannon, J. Houstek, and J. Nedergaard Brown adipose tissue. More than an effector of thermogenesis? Ann N Y Acad Sci 856 1998 171 187
    • (1998) Ann N y Acad Sci , vol.856 , pp. 171-187
    • Cannon, B.1    Houstek, J.2    Nedergaard, J.3
  • 35
    • 79751503329 scopus 로고    scopus 로고
    • Brown adipose tissue activity controls triglyceride clearance
    • A. Bartelt, O.T. Bruns, and R. Reimer Brown adipose tissue activity controls triglyceride clearance Nat Med 17 2 2011 200 205
    • (2011) Nat Med , vol.17 , Issue.2 , pp. 200-205
    • Bartelt, A.1    Bruns, O.T.2    Reimer, R.3
  • 36
    • 79952160358 scopus 로고    scopus 로고
    • New powers of brown fat: Fighting the metabolic syndrome
    • J. Nedergaard, T. Bengtsson, and B. Cannon New powers of brown fat: fighting the metabolic syndrome Cell Metab 13 3 2011 238 240
    • (2011) Cell Metab , vol.13 , Issue.3 , pp. 238-240
    • Nedergaard, J.1    Bengtsson, T.2    Cannon, B.3
  • 38
    • 33748366392 scopus 로고    scopus 로고
    • Regulatory circuits controlling white versus brown adipocyte differentiation
    • J.B. Hansen, and K. Kristiansen Regulatory circuits controlling white versus brown adipocyte differentiation Biochem J 398 2 2006 153 168
    • (2006) Biochem J , vol.398 , Issue.2 , pp. 153-168
    • Hansen, J.B.1    Kristiansen, K.2
  • 39
    • 84856970831 scopus 로고    scopus 로고
    • Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells
    • R.K. Gupta, R.J. Mepani, and S. Kleiner Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells Cell Metab 15 2 2012 230 239
    • (2012) Cell Metab , vol.15 , Issue.2 , pp. 230-239
    • Gupta, R.K.1    Mepani, R.J.2    Kleiner, S.3
  • 40
    • 84859465056 scopus 로고    scopus 로고
    • In vivo identification of bipotential adipocyte progenitors recruited by beta3-adrenoceptor activation and high-fat feeding
    • Y.H. Lee, A.P. Petkova, and E.P. Mottillo In vivo identification of bipotential adipocyte progenitors recruited by beta3-adrenoceptor activation and high-fat feeding Cell Metab 15 4 2012 480 491
    • (2012) Cell Metab , vol.15 , Issue.4 , pp. 480-491
    • Lee, Y.H.1    Petkova, A.P.2    Mottillo, E.P.3
  • 41
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/skeletal muscle switch
    • P. Seale, B. Bjork, and W. Yang PRDM16 controls a brown fat/skeletal muscle switch Nature 454 7207 2008 961 967
    • (2008) Nature , vol.454 , Issue.7207 , pp. 961-967
    • Seale, P.1    Bjork, B.2    Yang, W.3
  • 42
    • 84856954303 scopus 로고    scopus 로고
    • The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells
    • K.V. Tran, O. Gealekman, and A. Frontini The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells Cell Metab 15 2 2012 222 229
    • (2012) Cell Metab , vol.15 , Issue.2 , pp. 222-229
    • Tran, K.V.1    Gealekman, O.2    Frontini, A.3
  • 43
    • 34248372084 scopus 로고    scopus 로고
    • Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
    • J.A. Timmons, K. Wennmalm, and O. Larsson Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages Proc Natl Acad Sci U S A 104 11 2007 4401 4406
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.11 , pp. 4401-4406
    • Timmons, J.A.1    Wennmalm, K.2    Larsson, O.3
  • 44
    • 52649143796 scopus 로고    scopus 로고
    • Brown fat and skeletal muscle: Unlikely cousins?
    • S.R. Farmer Brown fat and skeletal muscle: unlikely cousins? Cell 134 5 2008 726 727
    • (2008) Cell , vol.134 , Issue.5 , pp. 726-727
    • Farmer, S.R.1
  • 45
    • 77952623888 scopus 로고    scopus 로고
    • The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
    • G. Barbatelli, I. Murano, and L. Madsen The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation Am J Physiol Endocrinol Metab 298 6 2010 E1244 E1253
    • (2010) Am J Physiol Endocrinol Metab , vol.298 , Issue.6 , pp. E1244-E1253
    • Barbatelli, G.1    Murano, I.2    Madsen, L.3
  • 46
    • 84900560773 scopus 로고    scopus 로고
    • Central sympathetic innervations to visceral and subcutaneous white adipose tissue
    • N.L. Nguyen, J. Randall, and B.W. Banfield Central sympathetic innervations to visceral and subcutaneous white adipose tissue Am J Physiol Regul Integr Comp Physiol 306 6 2014 R375 R386
    • (2014) Am J Physiol Regul Integr Comp Physiol , vol.306 , Issue.6 , pp. R375-R386
    • Nguyen, N.L.1    Randall, J.2    Banfield, B.W.3
  • 47
    • 0036839976 scopus 로고    scopus 로고
    • Selective parasympathetic innervation of subcutaneous and intra-abdominal fat-functional implications
    • F. Kreier, E. Fliers, and P.J. Voshol Selective parasympathetic innervation of subcutaneous and intra-abdominal fat-functional implications J Clin Invest 110 9 2002 1243 1250
    • (2002) J Clin Invest , vol.110 , Issue.9 , pp. 1243-1250
    • Kreier, F.1    Fliers, E.2    Voshol, P.J.3
  • 48
    • 84868526381 scopus 로고    scopus 로고
    • Neurochemical characterization and sexual dimorphism of projections from the brain to abdominal and subcutaneous white adipose tissue in the rat
    • E.S. Adler, J.H. Hollis, and I.J. Clarke Neurochemical characterization and sexual dimorphism of projections from the brain to abdominal and subcutaneous white adipose tissue in the rat J Neurosci 32 45 2012 15913 15921
    • (2012) J Neurosci , vol.32 , Issue.45 , pp. 15913-15921
    • Adler, E.S.1    Hollis, J.H.2    Clarke, I.J.3
  • 49
    • 42449086900 scopus 로고    scopus 로고
    • Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome
    • N.C. Bingham, K.K. Anderson, and A.L. Reuter Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome Endocrinology 149 5 2008 2138 2148
    • (2008) Endocrinology , vol.149 , Issue.5 , pp. 2138-2148
    • Bingham, N.C.1    Anderson, K.K.2    Reuter, A.L.3
  • 50
    • 33745907268 scopus 로고    scopus 로고
    • RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors
    • S. Musatov, W. Chen, and D.W. Pfaff RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors Proc Natl Acad Sci U S A 103 27 2006 10456 10460
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.27 , pp. 10456-10460
    • Musatov, S.1    Chen, W.2    Pfaff, D.W.3
  • 51
    • 33751172993 scopus 로고    scopus 로고
    • White adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervation
    • A. Giordano, C.K. Song, and R.R. Bowers White adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervation Am J Physiol Regul Integr Comp Physiol 291 5 2006 R1243 R1255
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291 , Issue.5 , pp. R1243-R1255
    • Giordano, A.1    Song, C.K.2    Bowers, R.R.3
  • 52
    • 34447647992 scopus 로고    scopus 로고
    • Evidence for parasympathetic innervation of white adipose tissue, clearing up some vagaries
    • author reply R550-542, discussion R553-544
    • F. Kreier, and R.M. Buijs Evidence for parasympathetic innervation of white adipose tissue, clearing up some vagaries Am J Physiol Regul Integr Comp Physiol 293 1 2007 R548 R549 author reply R550-542, discussion R553-544
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293 , Issue.1 , pp. R548-R549
    • Kreier, F.1    Buijs, R.M.2
  • 54
    • 84872144478 scopus 로고    scopus 로고
    • Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications
    • M.J. Lee, Y. Wu, and S.K. Fried Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications Mol Asp Med 34 1 2013 1 11
    • (2013) Mol Asp Med , vol.34 , Issue.1 , pp. 1-11
    • Lee, M.J.1    Wu, Y.2    Fried, S.K.3
  • 55
    • 0025299388 scopus 로고
    • "portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes
    • P. Bjorntorp "Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes Arteriosclerosis 10 4 1990 493 496
    • (1990) Arteriosclerosis , vol.10 , Issue.4 , pp. 493-496
    • Bjorntorp, P.1
  • 56
    • 77951698512 scopus 로고    scopus 로고
    • Inflammatory mediators of hepatic steatosis
    • E. Hijona, L. Hijona, and J.I. Arenas Inflammatory mediators of hepatic steatosis Mediat Inflamm 2010 2010 837419
    • (2010) Mediat Inflamm , vol.2010 , pp. 837419
    • Hijona, E.1    Hijona, L.2    Arenas, J.I.3
  • 57
    • 34548167210 scopus 로고    scopus 로고
    • Mechanisms controlling adipose tissue metabolism by the sympathetic nervous system: Anatomical and molecular aspects
    • S. Collins, R.H. Migliorini, and T.J. Bartness Mechanisms controlling adipose tissue metabolism by the sympathetic nervous system: anatomical and molecular aspects Handbook of contemporary neuropharmacology 2007
    • (2007) Handbook of Contemporary Neuropharmacology
    • Collins, S.1    Migliorini, R.H.2    Bartness, T.J.3
  • 58
    • 84908152559 scopus 로고    scopus 로고
    • Neural innervation of white adipose tissue and the control of lipolysis
    • [Epub ahead of print]
    • T.J. Bartness, Y. Liu, and Y.B. Shrestha Neural innervation of white adipose tissue and the control of lipolysis Front Neuroendocrinol 2014 Apr 13 10.1016/j.yfrne.2014.04.001 [Epub ahead of print]
    • (2014) Front Neuroendocrinol
    • Bartness, T.J.1    Liu, Y.2    Shrestha, Y.B.3
  • 59
    • 0035280191 scopus 로고    scopus 로고
    • Neurochemical phenotype of sympathetic nervous system outflow from brain to white fat
    • H. Shi, and T.J. Bartness Neurochemical phenotype of sympathetic nervous system outflow from brain to white fat Brain Res Bull 54 4 2001 375 385
    • (2001) Brain Res Bull , vol.54 , Issue.4 , pp. 375-385
    • Shi, H.1    Bartness, T.J.2
  • 60
    • 0036619442 scopus 로고    scopus 로고
    • Seasonal changes in adiposity: The roles of the photoperiod, melatonin and other hormones, and sympathetic nervous system
    • T.J. Bartness, G.E. Demas, and C.K. Song Seasonal changes in adiposity: the roles of the photoperiod, melatonin and other hormones, and sympathetic nervous system Exp Biol Med (Maywood) 227 6 2002 363 376
    • (2002) Exp Biol Med (Maywood) , vol.227 , Issue.6 , pp. 363-376
    • Bartness, T.J.1    Demas, G.E.2    Song, C.K.3
  • 61
    • 0034864984 scopus 로고    scopus 로고
    • The role of the hypothalamic melanocortin system in behavioral appetitive processes
    • S.C. Benoit, A.L. Tracy, and E.L. Air The role of the hypothalamic melanocortin system in behavioral appetitive processes Pharmacol Biochem Behav 69 3-4 2001 603 609
    • (2001) Pharmacol Biochem Behav , vol.69 , Issue.34 , pp. 603-609
    • Benoit, S.C.1    Tracy, A.L.2    Air, E.L.3
  • 62
    • 0034890282 scopus 로고    scopus 로고
    • CNS sympathetic outflow neurons to white fat that express MEL receptors may mediate seasonal adiposity
    • C.K. Song, and T.J. Bartness CNS sympathetic outflow neurons to white fat that express MEL receptors may mediate seasonal adiposity Am J Physiol Regul Integr Comp Physiol 281 2 2001 R666 R672
    • (2001) Am J Physiol Regul Integr Comp Physiol , vol.281 , Issue.2 , pp. R666-R672
    • Song, C.K.1    Bartness, T.J.2
  • 63
    • 0033817810 scopus 로고    scopus 로고
    • Melanocortins and body weight: A tale of two receptors
    • D.E. Cummings, and M.W. Schwartz Melanocortins and body weight: a tale of two receptors Nat Genet 26 1 2000 8 9
    • (2000) Nat Genet , vol.26 , Issue.1 , pp. 8-9
    • Cummings, D.E.1    Schwartz, M.W.2
  • 64
    • 0037320466 scopus 로고    scopus 로고
    • The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat
    • P.D. Raposinho, R.B. White, and M.L. Aubert The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat J Neuroendocrinol 15 2 2003 173 181
    • (2003) J Neuroendocrinol , vol.15 , Issue.2 , pp. 173-181
    • Raposinho, P.D.1    White, R.B.2    Aubert, M.L.3
  • 65
    • 27144523482 scopus 로고    scopus 로고
    • Melanocortin-4 receptor mRNA is expressed in sympathetic nervous system outflow neurons to white adipose tissue
    • C.K. Song, R.M. Jackson, and R.B. Harris Melanocortin-4 receptor mRNA is expressed in sympathetic nervous system outflow neurons to white adipose tissue Am J Physiol Regul Integr Comp Physiol 289 5 2005 R1467 R1476
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289 , Issue.5 , pp. R1467-R1476
    • Song, C.K.1    Jackson, R.M.2    Harris, R.B.3
  • 66
    • 36048955043 scopus 로고    scopus 로고
    • The central melanocortin system directly controls peripheral lipid metabolism
    • R. Nogueiras, P. Wiedmer, and D. Perez-Tilve The central melanocortin system directly controls peripheral lipid metabolism J Clin Invest 117 11 2007 3475 3488
    • (2007) J Clin Invest , vol.117 , Issue.11 , pp. 3475-3488
    • Nogueiras, R.1    Wiedmer, P.2    Perez-Tilve, D.3
  • 67
    • 0034456398 scopus 로고    scopus 로고
    • A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse
    • A.A. Butler, R.A. Kesterson, and K. Khong A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse Endocrinology 141 9 2000 3518 3521
    • (2000) Endocrinology , vol.141 , Issue.9 , pp. 3518-3521
    • Butler, A.A.1    Kesterson, R.A.2    Khong, K.3
  • 68
    • 0344406153 scopus 로고    scopus 로고
    • Differential sensitivity to central leptin and insulin in male and female rats
    • D.J. Clegg, C.A. Riedy, and K.A. Smith Differential sensitivity to central leptin and insulin in male and female rats Diabetes 52 3 2003 682 687
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 682-687
    • Clegg, D.J.1    Riedy, C.A.2    Smith, K.A.3
  • 69
    • 33745298324 scopus 로고    scopus 로고
    • Gonadal hormones determine sensitivity to central leptin and insulin
    • D.J. Clegg, L.M. Brown, and S.C. Woods Gonadal hormones determine sensitivity to central leptin and insulin Diabetes 55 4 2006 978 987
    • (2006) Diabetes , vol.55 , Issue.4 , pp. 978-987
    • Clegg, D.J.1    Brown, L.M.2    Woods, S.C.3
  • 70
    • 0032059835 scopus 로고    scopus 로고
    • Effects of the menopause transition on body fatness and body fat distribution
    • A. Tchernof, and E.T. Poehlman Effects of the menopause transition on body fatness and body fat distribution Obes Res 6 3 1998 246 254
    • (1998) Obes Res , vol.6 , Issue.3 , pp. 246-254
    • Tchernof, A.1    Poehlman, E.T.2
  • 71
    • 79551506567 scopus 로고    scopus 로고
    • Brain insulin controls adipose tissue lipolysis and lipogenesis
    • T. Scherer, J. O'Hare, and K. Diggs-Andrews Brain insulin controls adipose tissue lipolysis and lipogenesis Cell Metab 13 2 2011 183 194
    • (2011) Cell Metab , vol.13 , Issue.2 , pp. 183-194
    • Scherer, T.1    O'Hare, J.2    Diggs-Andrews, K.3
  • 72
    • 1642368840 scopus 로고    scopus 로고
    • Anterograde transneuronal viral tracing of central viscerosensory pathways in rats
    • L. Rinaman, and G. Schwartz Anterograde transneuronal viral tracing of central viscerosensory pathways in rats J Neurosci 24 11 2004 2782 2786
    • (2004) J Neurosci , vol.24 , Issue.11 , pp. 2782-2786
    • Rinaman, L.1    Schwartz, G.2
  • 73
    • 84859613818 scopus 로고    scopus 로고
    • Sympathetic activation by chemical stimulation of white adipose tissues in rats
    • Z. Shi, W.W. Chen, and X.Q. Xiong Sympathetic activation by chemical stimulation of white adipose tissues in rats J Appl Physiol (1985) 112 6 2012 1008 1014
    • (2012) J Appl Physiol (1985) , vol.112 , Issue.6 , pp. 1008-1014
    • Shi, Z.1    Chen, W.W.2    Xiong, X.Q.3
  • 74
    • 0033525580 scopus 로고    scopus 로고
    • Reflex effects from leptin sensors in the white adipose tissue of the epididymis to the efferent activity of the sympathetic and vagus nerve in the rat
    • A. Niijima Reflex effects from leptin sensors in the white adipose tissue of the epididymis to the efferent activity of the sympathetic and vagus nerve in the rat Neurosci Lett 262 2 1999 125 128
    • (1999) Neurosci Lett , vol.262 , Issue.2 , pp. 125-128
    • Niijima, A.1
  • 76
    • 0037414623 scopus 로고    scopus 로고
    • Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure
    • G. Cano, A.M. Passerin, and J.C. Schiltz Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure J Comp Neurol 460 3 2003 303 326
    • (2003) J Comp Neurol , vol.460 , Issue.3 , pp. 303-326
    • Cano, G.1    Passerin, A.M.2    Schiltz, J.C.3
  • 77
    • 0037139340 scopus 로고    scopus 로고
    • The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat
    • B.J. Oldfield, M.E. Giles, and A. Watson The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat Neuroscience 110 3 2002 515 526
    • (2002) Neuroscience , vol.110 , Issue.3 , pp. 515-526
    • Oldfield, B.J.1    Giles, M.E.2    Watson, A.3
  • 78
    • 0012829948 scopus 로고
    • Adrenergic innervation of adipose tissue examined by fluorescence microscopy
    • C. Wirsen Adrenergic innervation of adipose tissue examined by fluorescence microscopy Nature 202 1964 913
    • (1964) Nature , vol.202 , pp. 913
    • Wirsen, C.1
  • 79
    • 0002803715 scopus 로고
    • Distribution of adrenergic nerve fibers in brown and white adipose tissue
    • A. Renold, G. Cahill, American Physiological Society Washington, DC
    • C. Wirsen Distribution of adrenergic nerve fibers in brown and white adipose tissue A. Renold, G. Cahill, Adipose tissue 1965 American Physiological Society Washington, DC
    • (1965) Adipose Tissue
    • Wirsen, C.1
  • 80
    • 0033053660 scopus 로고    scopus 로고
    • GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue
    • S.F. Morrison, A.F. Sved, and A.M. Passerin GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue Am J Physiol 276 2 Pt 2 1999 R290 R297
    • (1999) Am J Physiol , vol.276 , Issue.2 , pp. R290-R297
    • Morrison, S.F.1    Sved, A.F.2    Passerin, A.M.3
  • 81
    • 0142164971 scopus 로고    scopus 로고
    • Excitatory amino acid receptor activation in the raphe pallidus area mediates prostaglandin-evoked thermogenesis
    • C.J. Madden, and S.F. Morrison Excitatory amino acid receptor activation in the raphe pallidus area mediates prostaglandin-evoked thermogenesis Neuroscience 122 1 2003 5 15
    • (2003) Neuroscience , vol.122 , Issue.1 , pp. 5-15
    • Madden, C.J.1    Morrison, S.F.2
  • 82
    • 33750024524 scopus 로고    scopus 로고
    • Involvement of medullary GABAergic and serotonergic raphe neurons in respiratory control: Electrophysiological and immunohistochemical studies in rats
    • Y. Cao, K. Matsuyama, and Y. Fujito Involvement of medullary GABAergic and serotonergic raphe neurons in respiratory control: electrophysiological and immunohistochemical studies in rats Neurosci Res 56 3 2006 322 331
    • (2006) Neurosci Res , vol.56 , Issue.3 , pp. 322-331
    • Cao, Y.1    Matsuyama, K.2    Fujito, Y.3
  • 83
    • 51149096739 scopus 로고    scopus 로고
    • Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: Neuroanatomical and functional evidence
    • C.K. Song, C.H. Vaughan, and E. Keen-Rhinehart Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: neuroanatomical and functional evidence Am J Physiol Regul Integr Comp Physiol 295 2 2008 R417 R428
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.295 , Issue.2 , pp. R417-R428
    • Song, C.K.1    Vaughan, C.H.2    Keen-Rhinehart, E.3
  • 84
    • 33947387967 scopus 로고    scopus 로고
    • Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue
    • A. Voss-Andreae, J.G. Murphy, and K.L. Ellacott Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue Endocrinology 148 4 2007 1550 1560
    • (2007) Endocrinology , vol.148 , Issue.4 , pp. 1550-1560
    • Voss-Andreae, A.1    Murphy, J.G.2    Ellacott, K.L.3
  • 85
    • 35548962415 scopus 로고    scopus 로고
    • Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation
    • M.N. Brito, N.A. Brito, and D.J. Baro Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation Endocrinology 148 11 2007 5339 5347
    • (2007) Endocrinology , vol.148 , Issue.11 , pp. 5339-5347
    • Brito, M.N.1    Brito, N.A.2    Baro, D.J.3
  • 86
    • 77956030149 scopus 로고    scopus 로고
    • The endogenous actions of hypothalamic peptides on brown adipose tissue thermogenesis in the rat
    • A.N. Verty, A.M. Allen, and B.J. Oldfield The endogenous actions of hypothalamic peptides on brown adipose tissue thermogenesis in the rat Endocrinology 151 9 2010 4236 4246
    • (2010) Endocrinology , vol.151 , Issue.9 , pp. 4236-4246
    • Verty, A.N.1    Allen, A.M.2    Oldfield, B.J.3
  • 87
    • 0037086814 scopus 로고    scopus 로고
    • Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice
    • A.C. Haynes, H. Chapman, and C. Taylor Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice Regul Pept 104 1-3 2002 153 159
    • (2002) Regul Pept , vol.104 , Issue.13 , pp. 153-159
    • Haynes, A.C.1    Chapman, H.2    Taylor, C.3
  • 88
    • 0033943102 scopus 로고    scopus 로고
    • Reciprocal relation of food intake and sympathetic activity: Experimental observations and clinical implications
    • G.A. Bray Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications Int J Obes Relat Metab Disord 24 Suppl. 2 2000 S8 S17
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. S8-S17
    • Bray, G.A.1
  • 89
    • 0037403951 scopus 로고    scopus 로고
    • Characterization of MCH-mediated obesity in mice
    • M. Ito, A. Gomori, and A. Ishihara Characterization of MCH-mediated obesity in mice Am J Physiol Endocrinol Metab 284 5 2003 E940 E945
    • (2003) Am J Physiol Endocrinol Metab , vol.284 , Issue.5 , pp. E940-E945
    • Ito, M.1    Gomori, A.2    Ishihara, A.3
  • 90
    • 0042190566 scopus 로고    scopus 로고
    • Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype
    • G. Segal-Lieberman, R.L. Bradley, and E. Kokkotou Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype Proc Natl Acad Sci U S A 100 17 2003 10085 10090
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.17 , pp. 10085-10090
    • Segal-Lieberman, G.1    Bradley, R.L.2    Kokkotou, E.3
  • 91
    • 0034992322 scopus 로고    scopus 로고
    • Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity
    • J. Hara, C.T. Beuckmann, and T. Nambu Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity Neuron 30 2 2001 345 354
    • (2001) Neuron , vol.30 , Issue.2 , pp. 345-354
    • Hara, J.1    Beuckmann, C.T.2    Nambu, T.3
  • 92
    • 11144301817 scopus 로고    scopus 로고
    • Reverse pharmacology of orexin: From an orphan GPCR to integrative physiology
    • T. Sakurai Reverse pharmacology of orexin: from an orphan GPCR to integrative physiology Regul Pept 126 1-2 2005 3 10
    • (2005) Regul Pept , vol.126 , Issue.12 , pp. 3-10
    • Sakurai, T.1
  • 93
    • 84883805981 scopus 로고    scopus 로고
    • An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis
    • S.F. Morrison, C.J. Madden, and D. Tupone An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis Adipocyte 1 2 2012 116 120
    • (2012) Adipocyte , vol.1 , Issue.2 , pp. 116-120
    • Morrison, S.F.1    Madden, C.J.2    Tupone, D.3
  • 94
    • 84857192445 scopus 로고    scopus 로고
    • Genetic modulation of plasma NPY stress response is suppressed in substance abuse: Association with clinical outcomes
    • K. Xu, K.A. Hong, and Z. Zhou Genetic modulation of plasma NPY stress response is suppressed in substance abuse: association with clinical outcomes Psychoneuroendocrinology 37 4 2012 554 564
    • (2012) Psychoneuroendocrinology , vol.37 , Issue.4 , pp. 554-564
    • Xu, K.1    Hong, K.A.2    Zhou, Z.3
  • 95
    • 84873362255 scopus 로고    scopus 로고
    • Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN
    • Y.C. Shi, J. Lau, and Z. Lin Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN Cell Metab 17 2 2013 236 248
    • (2013) Cell Metab , vol.17 , Issue.2 , pp. 236-248
    • Shi, Y.C.1    Lau, J.2    Lin, Z.3
  • 96
    • 84883475357 scopus 로고    scopus 로고
    • K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis
    • S. Tovar, L. Paeger, and S. Hess K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis Cell Metab 18 3 2013 445 455
    • (2013) Cell Metab , vol.18 , Issue.3 , pp. 445-455
    • Tovar, S.1    Paeger, L.2    Hess, S.3
  • 97
    • 0022475728 scopus 로고
    • Effect of glucose and other hexoses on efferent discharges of brown adipose tissue nerves
    • A. Niijima Effect of glucose and other hexoses on efferent discharges of brown adipose tissue nerves Am J Physiol 251 2 Pt 2 1986 R240 R242
    • (1986) Am J Physiol , vol.251 , Issue.2 , pp. R240-R242
    • Niijima, A.1
  • 98
    • 0024162399 scopus 로고
    • Sympathetic activity following paraventricular injections of glucose and insulin
    • T. Sakaguchi, and G.A. Bray Sympathetic activity following paraventricular injections of glucose and insulin Brain Res Bull 21 1 1988 25 29
    • (1988) Brain Res Bull , vol.21 , Issue.1 , pp. 25-29
    • Sakaguchi, T.1    Bray, G.A.2
  • 99
    • 0024428785 scopus 로고
    • Interaction of intracerebroventricular insulin and glucose in the regulation of the activity of sympathetic efferent nerves to brown adipose tissue in lean and obese Zucker rats
    • S.J. Holt, and D.A. York Interaction of intracerebroventricular insulin and glucose in the regulation of the activity of sympathetic efferent nerves to brown adipose tissue in lean and obese Zucker rats Brain Res 500 1-2 1989 384 388
    • (1989) Brain Res , vol.500 , Issue.12 , pp. 384-388
    • Holt, S.J.1    York, D.A.2
  • 100
    • 0024853462 scopus 로고
    • Effects of 2-deoxy-D-glucose on sympathetic nerve activity to interscapular brown adipose tissue
    • M. Egawa, H. Yoshimatsu, and G.A. Bray Effects of 2-deoxy-D-glucose on sympathetic nerve activity to interscapular brown adipose tissue Am J Physiol 257 6 Pt 2 1989 R1377 R1385
    • (1989) Am J Physiol , vol.257 , Issue.6 , pp. R1377-R1385
    • Egawa, M.1    Yoshimatsu, H.2    Bray, G.A.3
  • 101
    • 34247280674 scopus 로고    scopus 로고
    • Lateral hypothalamic 'command neurons' with axonal projections to regions involved in both feeding and thermogenesis
    • B.J. Oldfield, A.M. Allen, and P. Davern Lateral hypothalamic 'command neurons' with axonal projections to regions involved in both feeding and thermogenesis Eur J Neurosci 25 8 2007 2404 2412
    • (2007) Eur J Neurosci , vol.25 , Issue.8 , pp. 2404-2412
    • Oldfield, B.J.1    Allen, A.M.2    Davern, P.3
  • 102
    • 84933182488 scopus 로고    scopus 로고
    • Identification of CNS neurons with polysynaptic connections to both the sympathetic and parasympathetic innervation of the submandibular gland
    • [Epub ahead of print]
    • N.S. Hettigoda, A.Y. Fong, and E. Badoer Identification of CNS neurons with polysynaptic connections to both the sympathetic and parasympathetic innervation of the submandibular gland Brain Struct Funct 2014 May 3 10.1007/s00429-014-0781-1 [Epub ahead of print]
    • (2014) Brain Struct Funct
    • Hettigoda, N.S.1    Fong, A.Y.2    Badoer, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.