Th1/Th2 paradigm extended: Macrophage polarization as an unappreciated pathogen-driven escape mechanism?

Frontiers in Immunology

Volumn 5, Issue NOV, 2014, Pages

  Muraille, Eric ^a   Leo, Oberdan ^a   Moser, Muriel ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Amino acid metabolism; Hypoxia; Immune escape strategy; Infection; Iron; Macrophage polarization; Metabolic switch; PPARs

Indexed keywords

CD163 ANTIGEN; CD36 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; DEFENSIN; FERRITIN; GAMMA INTERFERON; GLUCOSE TRANSPORTER 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1; INDOLEAMINE 2,3 DIOXYGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; MANNOSE RECEPTOR; MATRILYSIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; RETINOID X RECEPTOR; STAT6 PROTEIN; TOLL LIKE RECEPTOR 2; TRYPTOPHAN; TRYPTOPHAN 2,3 DIOXYGENASE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

AMINO ACID METABOLISM; ANTIMICROBIAL ACTIVITY; BACTERIAL VIRULENCE; CELL DIFFERENTIATION; CELL POLARITY; CELL PROLIFERATION; CELL VIABILITY; DOWN REGULATION; GENE EXPRESSION; HOST PATHOGEN INTERACTION; HUMAN; HYPOXIA; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; IRON METABOLISM; LIPID METABOLISM; M1 MACROPHAGE; M2 MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE POLARIZATION; NONHUMAN; PATHOGEN LOAD; REVIEW; TH1 CELL; TH2 CELL; UPREGULATION;

EID: 84919460745     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00603     Document Type: Review

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