Inhibition of increased indoleamine 2,3-dioxygenase activity attenuates Toxoplasma gondii replication in the lung during acute infection

Cytokine

Volumn 59, Issue 2, 2012, Pages 245-251

  Murakami, Yuki ^a   Hoshi, Masato ^b   Hara, Akira ^b   Takemura, Masao ^b   Arioka, Yuko ^a   Yamamoto, Yasuko ^a   Matsunami, Hidetoshi ^a   Funato, Tadao ^c   Seishima, Mitsuru ^b   Saito, Kuniaki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c TOHOKU FUKUSHI UNIVERSITY   (Japan)

Author keywords

1 Methyl d,l tryptophan (1MT); IDO gene deficient mice; Indoleamine 2,3 dioxygenase (IDO); Inflammation; Toxoplasma gondii (T. gondii)

Indexed keywords

1 METHYL TRYPTOPHAN; CYTOKINE; INDOLEAMINE 2,3 DIOXYGENASE; MESSENGER RNA; TRYPTOPHAN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE; GENE EXPRESSION; IN VIVO STUDY; INFECTION PREVENTION; INFLAMMATION; KNOCKOUT MOUSE; LUNG INFECTION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE CLEARANCE; PARASITE VIRULENCE; PRIORITY JOURNAL; SURFACE ANTIGEN GENE 2; TOXOPLASMA GONDII; TOXOPLASMOSIS; WILD TYPE;

ACUTE DISEASE; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INFLAMMATION; LIFE CYCLE STAGES; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTOZOAN PROTEINS; RNA, MESSENGER; TOXOPLASMA; TOXOPLASMOSIS; TRYPTOPHAN;

MUS; TOXOPLASMA GONDII;

EID: 84862336413     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.04.022     Document Type: Article

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