Hypoxia in leishmania major skin lesions impairs the NO-dependent leishmanicidal activity of macrophages

Journal of Investigative Dermatology

Volumn 134, Issue 9, 2014, Pages 2339-2346

  Mahnke, Alexander ^a   Meier, Robert J ^b   Schatz, Valentin ^a   Hofmann, Julian ^a   Castiglione, Kirstin ^a   Schleicher, Ulrike ^a   Wolfbeis, Otto S ^b   Bogdan, Christian ^a   Jantsch, Jonathan ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; OXYGEN; 1 [N (2 AMINOETHYL) N (2 AMINOETHYL)AMINO]DIAZEN 1 IUM 1,2 DIOLATE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG; ARG1 PROTEIN, MOUSE; ARGINASE; NOS2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; HYPOXEMIA; LEISHMANIA MAJOR; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OXYGEN TENSION; OXYGEN TISSUE LEVEL; PARASITE CLEARANCE; PARASITE CONTROL; PARASITE LOAD; PHENOTYPE; PRIORITY JOURNAL; REOXYGENATION; SKIN LEISHMANIASIS; TISSUE OXYGENATION; WILD TYPE; CELL FUNCTION; CORRELATION ANALYSIS; HYPOXIA; LEISHMANIASIS; SKIN INJURY; AIR QUALITY CONTROL; ANIMAL; ANOXIA; BAGG ALBINO MOUSE; C57BL MOUSE; GENETICS; KNOCKOUT MOUSE; METABOLISM; PARASITOLOGY; PATHOLOGY; SKIN;

ANIMALS; ANOXIA; ARGINASE; ATMOSPHERE EXPOSURE CHAMBERS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXYGEN; PHENOTYPE; SKIN;

EID: 84906322474     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.121     Document Type: Article

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