Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

PLoS Pathogens

Volumn 9, Issue 11, 2013, Pages

  Esser von Bieren, Julia ^a   Mosconi, Ilaria ^a   Guiet, Romain ^a   Piersgilli, Alessandra ^b   Volpe, Beatrice ^a   Chen, Fei ^c   Gause, William C ^c   Seitz, Arne ^a   Verbeek, J Sjef ^d   Harris, Nicola L ^a  

^a EPFL   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c Rutgers The State University of New Jersey   (United States)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTISERUM; ARGINASE 1; CD16 ANTIGEN; CD32 ANTIGEN; CD64 ANTIGEN; COMPLEMENT COMPONENT C3; FC RECEPTOR; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G3; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 12P40; INTERLEUKIN 4 RECEPTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GASTROINTESTINAL MUCOSA; GENE EXPRESSION; GRANULOMA; HELIGMOSOMOIDES POLYGYRUS; HELMINTHIASIS; IMMOBILIZATION; IMMUNITY; IMMUNOFLUORESCENCE; LARVA; MACROPHAGE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PARASITE MIGRATION; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; TISSUE INJURY; TISSUE NECROSIS;

ANIMALS; ANTIBODIES, HELMINTH; ARGINASE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LARVA; MACROPHAGES; MICE; MICE, KNOCKOUT; NEMATOSPIROIDES DUBIUS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STRONGYLIDA INFECTIONS;

EID: 84888257272     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003771     Document Type: Article

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