Role of iron in experimental Mycobacterium avium infection

Journal of Clinical Virology

Volumn 20, Issue 3, 2001, Pages 117-122

  Gomes, M Salomé ^a,b   Boelaert, Johan R ^a,c   Appelberg, Rui ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

^c General Hospital St Jan   (Belgium)

Author keywords

AIDS; HIV; Iron; Opportunistic infections

Indexed keywords

DEFEROXAMINE; HYDROXYBENZYLETHYLENEDIAMINE DIACETIC ACID; IRON; IRON CHELATING AGENT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IRON METABOLISM; IRON OVERLOAD; IRON STORAGE; MACROPHAGE; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM AVIUM; NONHUMAN; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL;

ANIMALS; BONE MARROW; CELLS, CULTURED; DIET; FEMALE; IRON; IRON-DEXTRAN COMPLEX; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYCOBACTERIUM AVIUM; TUBERCULOSIS;

EID: 0035143276     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1386-6532(00)00135-9     Document Type: Article

References (43)

1. Susceptibility to leprosy is linked to the human NRAMP1 gene
2. Increased hepatic iron in the acquired immunodeficiency syndrome: an autopsy study
3. Effector mechanisms involved in cytokine-mediated bacteriostasis of Mycbacterium avium infections in murine macrophages
4. The role of macrophage activation and of Bcg-encoded functions(s) in the control of Mycobacterium avium infection in mice
5. The role of gamma interferon and tumor necrosis factor-α during the T cell independent and dependent phases of Mycobacterium avium infection
6. Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. I. Defective trigger on NK cells for NKCF production by target cells, and partial restoration by IL2
7. Nramp1: a link between intracellular iron transport and innate resistance to intracellular pathogens
8. Variations in the Nramp1 gene and susceptibility to tuberculosis in West Africans
9. Immunogenetics of leishmanial and mycobacterial infections: the Belem Family Study
10. Altered iron metabolism in HIV infection: mechanisms, possible consequences and proposals for management
11. Interferon γ-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron
12. The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin
13. Defects in sera from acquired immunodeficiency syndrome (AIDS) patients and from non-AIDS patients with Mycobacterium avium infection which decrease macrophage resistance to M. avium
14. Bone marrow macrophage iron grade and survival of HIV-seropositive patients
15. Role of iron in the pathogenesis of Mycobacterium avium infection in mice
16. Defects in cell-mediated immunity affect chronic, but not innate, resistance of mice to Mycobacterium avium infection
17. Resistance of virulent Mycobacterium avium to interferon-γ-mediated antimicrobial activity suggests additional signals for induction of mycobacteriostasis
18. Macrophage permissiveness for Legionella pneumophila growth modulated by iron
19. Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall
20. Evidence for a link between iron metabolism and Nramp1 gene function in innate resistance to Mycobacterium avium
21. Effects of iron deprivation on Mycobacterium avium growth
22. Improved clearance of Mycobacterium avium upon disruption of the iNOS gene
23. Etiologies, consequences and treatment of iron overload
24. Natural resistance to infection with intracellular pathogens: the NRAMP1 protein is recruited to the membrane of the phagosome
25. Analysis of the NRAMP1 and IFNγR1 genes in women with Mycobacterium avium-intracellulare pulmonary disease
26. The Mycobacterium avium complex
27. Human immunodeficiency virus disease-related neutropenia and the risk of hospitalization for bacterial infection
28. Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates
29. Neutropenia is associated with bacteremia in patients infected with the human immunodeficiency virus
30. Iron limitation and the γ-interferon-mediated antihistoplasma state of murine macrophages
31. Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives
32. A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection
33. Acquisition of iron bound to low molecular weight chelates by human monocyte-derived macrophages
34. Depressed neutrophil superoxide production in human immunodeficiency virus infection
35. Nitric oxide-mediated induction of Ferritin synthesis in J774 macrophages by inflammatory cytokines: role of selective iron regulatory protein-2 downregulation
36. Impairment of neutrophil antifungal activity against hyphae of Aspergillus fumigatus in children infected with human immunodeficiency virus
37. The respiratory burst oxidase
38. Natural killer (NK) cell activity during HIV infection: a decrease in NK activity is observed at the clonal level and is not restored after in vitro long-term culture of NK cells
39. Localization of NRAMP1 in macrophages: modulation with activation and infection
40. phox-/- mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs
41. Differential regulation of iron regulatory element binding proteins(s) in cell extracts of activated lymphocytes versus monocytes-macrophages
42. Iron regulates nitric oxide synthase activity by controlling nuclear transcription
43. Translational regulation via iron-responsive elements by the nitric oxide/No-synthase pathway