Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation

Journal of Biological Chemistry

Volumn 289, Issue 51, 2014, Pages 35246-35263

  Jolly, Lisa ^a   Stavrou, Anastasios ^a   Vanderstoken, Gilles ^d   Meliopoulos, Victoria A ^b   Habgood, Anthony ^a   Tatler, Amanda L ^a   Porte, Joanne ^a   Knox, Alan ^a   Weinreb, Paul ^c   Violette, Shelia ^c   Hussell, Tracy ^e   Kolb, Martin ^d   Stampflix, Martin R ^d   Schultz Cherry, Stacey ^b   Jenkins, Gisli ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c BIOGEN   (United States)

^d MCMASTER UNIVERSITY   (Canada)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELLS; COLLAGEN; CYTOLOGY; DEPOSITION; INTEGRATED CIRCUITS; MAMMALS; PULMONARY DISEASES;

APOPTOTIC CELLS; COLLAGEN DEPOSITION; DOMINANT NEGATIVE; EPITHELIAL CELLS; IDIOPATHIC PULMONARY FIBROSIS; KNOCK OUTS; TOLL-LIKE RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA;

CHEMICAL ACTIVATION;

ALPHAVBETA6 INTEGRIN; COLLAGEN; POLYINOSINIC POLYCYTIDYLIC ACID; RHO KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; TOLL LIKE RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2-METHYL-1-((4-METHYL-5-ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; ANTIVIRUS AGENT; INTEGRIN; TUMOR ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA A (H1N1); MOUSE; NONHUMAN; PROTEIN FUNCTION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DOG; DRUG EFFECTS; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOBLOTTING; INFLUENZA A VIRUS (H1N1); KNOCKOUT MOUSE; LUNG; MDCK CELL LINE; METABOLISM; ORTHOMYXOVIRUS INFECTION; PHOSPHORYLATION; PHYSIOLOGY; TRANSFORMED CELL LINE; VIROLOGY;

MUS;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ANTIGENS, NEOPLASM; ANTIVIRAL AGENTS; APOPTOSIS; CELL LINE, TRANSFORMED; COLLAGEN; DOGS; EPITHELIAL CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOBLOTTING; INFLUENZA A VIRUS, H1N1 SUBTYPE; INTEGRINS; LUNG; MADIN DARBY CANINE KIDNEY CELLS; MICE, INBRED C57BL; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; PHOSPHORYLATION; POLY I-C; RHO-ASSOCIATED KINASES; SMAD3 PROTEIN; TOLL-LIKE RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA;

EID: 84919361154     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.582262     Document Type: Article

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