Function-blocking integrin αvβ6 monoclonal antibodies: Distinct ligand-mimetic and nonligand-mimetic classes

Journal of Biological Chemistry

Volumn 279, Issue 17, 2004, Pages 17875-17887

  Weinreb, Paul H ^a   Simon, Kenneth J ^a   Rayhorn, Paul ^a   Yang, William J ^a   Leone, Diane R ^a   Dolinski, Brian M ^a   Pearse, Bradley R ^a   Yokota, Yukako ^a   Kawakatsu, Hisaaki ^b   Atakilit, Amha ^b   Sheppard, Dean ^b   Violette, Shelia M ^a  

^a BIOGEN   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; MONOCLONAL ANTIBODIES; POSITIVE IONS;

CROSS-REACTIVITY; DIVALENT CATIONS; EPITOPES; MOUSE;

BIOCHEMISTRY;

ALPHA5 INTEGRIN; ALPHAVBETA6 INTEGRIN; ARGINYLGLYCYLASPARTIC ACID; CATION; EPITOPE; FIBRONECTIN; LATENCY ASSOCIATED PEPTIDE; LIGAND; MONOCLONAL ANTIBODY; PEPTIDE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY ENGINEERING; ARTICLE; BINDING AFFINITY; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CROSS REACTION; HUMAN; IC 50; INTERNALIZATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BINDING, COMPETITIVE; CATIONS; CELL ADHESION; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITOPES; FIBRONECTINS; FLOW CYTOMETRY; HUMANS; IMMUNOASSAY; INHIBITORY CONCENTRATION 50; INTEGRINS; KINETICS; LIGANDS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; OLIGOPEPTIDES; PEPTIDES; PLATELET AGGREGATION; PROTEIN BINDING; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALIA;

EID: 2342445861     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312103200     Document Type: Article

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