-
1
-
-
23444434303
-
Spine biomechanics
-
Adams MA, Dolan P. 2005; Spine biomechanics. J Biomech 38: 1972-1983.
-
(2005)
J Biomech
, vol.38
, pp. 1972-1983
-
-
Adams, M.A.1
Dolan, P.2
-
2
-
-
33747355707
-
What is intervertebral disc degeneration, and what causes it?
-
Adams MA, Roughley PJ. 2006; What is intervertebral disc degeneration, and what causes it? Spine 31: 2151-2161.
-
(2006)
Spine
, vol.31
, pp. 2151-2161
-
-
Adams, M.A.1
Roughley, P.J.2
-
3
-
-
0032711845
-
Delayed expression of adeno-associated virus vector DNA
-
Afione SA, Wang J, Walsh S, et al. 1999; Delayed expression of adeno-associated virus vector DNA. Intervirology 42: 213-220.
-
(1999)
Intervirology
, vol.42
, pp. 213-220
-
-
Afione, S.A.1
Wang, J.2
Walsh, S.3
-
4
-
-
38649097225
-
Are animal models useful for studying human disc disorders/degeneration?
-
Alini M, Eisenstein SM, Ito K, et al. 2008; Are animal models useful for studying human disc disorders/degeneration? Eur Spine J 17: 2-19.
-
(2008)
Eur Spine J
, vol.17
, pp. 2-19
-
-
Alini, M.1
Eisenstein, S.M.2
Ito, K.3
-
5
-
-
80052632551
-
Biologic repair and regeneration of the intervertebral disk
-
An HS, Masuda K, Cs-Szabo G, et al. 2011; Biologic repair and regeneration of the intervertebral disk. J Am Acad Orthop Surg 19: 450-452.
-
(2011)
J Am Acad Orthop Surg
, vol.19
, pp. 450-452
-
-
An, H.S.1
Masuda, K.2
Cs-Szabo, G.3
-
6
-
-
40049100038
-
Two-year outcome after lumbar microdiscectomy versus microscopic sequestrectomy: part 1: evaluation of clinical outcome
-
Barth M, Weiss C, Thomé C. 2008; Two-year outcome after lumbar microdiscectomy versus microscopic sequestrectomy: part 1: evaluation of clinical outcome. Spine 33: 265-272.
-
(2008)
Spine
, vol.33
, pp. 265-272
-
-
Barth, M.1
Weiss, C.2
Thomé, C.3
-
7
-
-
57849168925
-
The Twin Spine Study: contributions to a changing view of disc degeneration
-
Battié MC, Videman T, Kaprio J, et al. 2009; The Twin Spine Study: contributions to a changing view of disc degeneration. Spine J 9: 47-59.
-
(2009)
Spine J
, vol.9
, pp. 47-59
-
-
Battié, M.C.1
Videman, T.2
Kaprio, J.3
-
8
-
-
14844303678
-
2004 Young Investigator Award winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration
-
Benneker LM, Heini PF, Alini M, et al. 2005; 2004 Young Investigator Award winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration. Spine 30: 167-173.
-
(2005)
Spine
, vol.30
, pp. 167-173
-
-
Benneker, L.M.1
Heini, P.F.2
Alini, M.3
-
9
-
-
0037108786
-
Cell viability in scoliotic discs in relation to disc deformity and nutrient levels
-
discussion, 2227-2228.
-
Bibby SR, Fairbank JC, Urban MR, et al. 2002; Cell viability in scoliotic discs in relation to disc deformity and nutrient levels. Spine 27: 2220-2228; discussion, 2227-2228.
-
(2002)
Spine
, vol.27
, pp. 2220-2228
-
-
Bibby, S.R.1
Fairbank, J.C.2
Urban, M.R.3
-
10
-
-
10444232467
-
Effect of nutrient deprivation on the viability of intervertebral disc cells
-
Bibby SR, Urban JP. 2004; Effect of nutrient deprivation on the viability of intervertebral disc cells. Eur Spine J 13: 695-701.
-
(2004)
Eur Spine J
, vol.13
, pp. 695-701
-
-
Bibby, S.R.1
Urban, J.P.2
-
11
-
-
14344255879
-
Metabolism of the intervertebral disc: effects of low levels of oxygen, glucose, and pH on rates of energy metabolism of bovine nucleus pulposus cells
-
Bibby SR, Jones DA, Ripley RM, et al. 2005; Metabolism of the intervertebral disc: effects of low levels of oxygen, glucose, and pH on rates of energy metabolism of bovine nucleus pulposus cells. Spine 30: 487-496.
-
(2005)
Spine
, vol.30
, pp. 487-496
-
-
Bibby, S.R.1
Jones, D.A.2
Ripley, R.M.3
-
12
-
-
0029008944
-
Aging and degeneration of the human intervertebral disc
-
Buckwalter JA. 1995; Aging and degeneration of the human intervertebral disc. Spine 20: 1307-1314.
-
(1995)
Spine
, vol.20
, pp. 1307-1314
-
-
Buckwalter, J.A.1
-
13
-
-
0036201899
-
Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators
-
Burke JG, Watson RW, McCormack D, et al. 2002; Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators. J Bone Joint Surg Br 84: 196-201.
-
(2002)
J Bone Joint Surg Br
, vol.84
, pp. 196-201
-
-
Burke, J.G.1
Watson, R.W.2
McCormack, D.3
-
14
-
-
57049157621
-
Scaffolding in tissue engineering: general approaches and tissue-specific considerations
-
Chan BP, Leong KW. 2008; Scaffolding in tissue engineering: general approaches and tissue-specific considerations. Eur Spine J 17(suppl 4): 467-479.
-
(2008)
Eur Spine J
, vol.17
, pp. 467-479
-
-
Chan, B.P.1
Leong, K.W.2
-
16
-
-
33750529139
-
Tissue-engineered intervertebral disc and chondrogenesis using human nucleus pulposus regulated through TGF-β1 in platelet-rich plasma
-
Chen WH, Lo WC, Lee JJ, et al. 2006; Tissue-engineered intervertebral disc and chondrogenesis using human nucleus pulposus regulated through TGF-β1 in platelet-rich plasma. J Cell Physiol 209: 744-754.
-
(2006)
J Cell Physiol
, vol.209
, pp. 744-754
-
-
Chen, W.H.1
Lo, W.C.2
Lee, J.J.3
-
17
-
-
0033839344
-
Intra-CSF administered recombinant adenovirus causes an immune response-mediated toxicity
-
Driesse MJ, Esandi MC, Kros JM, et al. 2000; Intra-CSF administered recombinant adenovirus causes an immune response-mediated toxicity. Gene Ther 7: 1401-1409.
-
(2000)
Gene Ther
, vol.7
, pp. 1401-1409
-
-
Driesse, M.J.1
Esandi, M.C.2
Kros, J.M.3
-
19
-
-
79955953364
-
Development of a novel automated cell isolation, expansion, and characterization platform
-
Franscini N, Wuertz K, Patocchi-Tenzer I, et al. 2011; Development of a novel automated cell isolation, expansion, and characterization platform. J Lab Autom 16: 204-213.
-
(2011)
J Lab Autom
, vol.16
, pp. 204-213
-
-
Franscini, N.1
Wuertz, K.2
Patocchi-Tenzer, I.3
-
20
-
-
0030790455
-
Nerve ingrowth into diseased intervertebral disc in chronic back pain
-
Freemont AJ, Peacock TE, Goupille P, et al. 1997; Nerve ingrowth into diseased intervertebral disc in chronic back pain. Lancet 350: 178-181.
-
(1997)
Lancet
, vol.350
, pp. 178-181
-
-
Freemont, A.J.1
Peacock, T.E.2
Goupille, P.3
-
21
-
-
0345411874
-
Disc chondrocyte transplantation in a canine model: a treatment for degenerated or damaged intervertebral disc
-
Ganey T, Libera J, Moos V, et al. 2003; Disc chondrocyte transplantation in a canine model: a treatment for degenerated or damaged intervertebral disc. Spine 28: 2609-2620.
-
(2003)
Spine
, vol.28
, pp. 2609-2620
-
-
Ganey, T.1
Libera, J.2
Moos, V.3
-
22
-
-
42949126727
-
The effects of recombinant human bone morphogenetic protein-2, recombinant human bone morphogenetic protein-12, and adenoviral bone morphogenetic protein-12 on matrix synthesis in human annulus fibrosis and nucleus pulposus cells
-
Gilbertson L, Ahn SH, Teng PN, et al. 2008; The effects of recombinant human bone morphogenetic protein-2, recombinant human bone morphogenetic protein-12, and adenoviral bone morphogenetic protein-12 on matrix synthesis in human annulus fibrosis and nucleus pulposus cells. Spine J 8: 449-456.
-
(2008)
Spine J
, vol.8
, pp. 449-456
-
-
Gilbertson, L.1
Ahn, S.H.2
Teng, P.N.3
-
23
-
-
0036668306
-
Autologous intervertebral disc cell implantation: a model using Psammomys obesus, the sand rat
-
Gruber HE, Johnson TL, Leslie K, et al. 2002; Autologous intervertebral disc cell implantation: a model using Psammomys obesus, the sand rat. Spine 27: 1626-1633.
-
(2002)
Spine
, vol.27
, pp. 1626-1633
-
-
Gruber, H.E.1
Johnson, T.L.2
Leslie, K.3
-
24
-
-
33846652876
-
Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated β-galactosidase in human and sand rat discs
-
Gruber HE, Ingram JA, Norton HJ, et al. 2007; Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated β-galactosidase in human and sand rat discs. Spine 32: 321-327.
-
(2007)
Spine
, vol.32
, pp. 321-327
-
-
Gruber, H.E.1
Ingram, J.A.2
Norton, H.J.3
-
25
-
-
33645574432
-
Nutrient supply and intervertebral disc metabolism
-
Grunhagen T, Wilde G, Soukane DM, et al. 2006; Nutrient supply and intervertebral disc metabolism. J Bone Joint Surg Am 88(suppl 2): 30-35.
-
(2006)
J Bone Joint Surg Am
, vol.88
, pp. 30-35
-
-
Grunhagen, T.1
Wilde, G.2
Soukane, D.M.3
-
26
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. 2003; LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302: 415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
27
-
-
0030977985
-
Effects of hydrostatic pressure on matrix synthesis and matrix metalloproteinase production in the human lumbar intervertebral disc
-
Handa T, Ishihara H, Ohshima H, et al. 1997; Effects of hydrostatic pressure on matrix synthesis and matrix metalloproteinase production in the human lumbar intervertebral disc. Spine 22: 1085-1091.
-
(1997)
Spine
, vol.22
, pp. 1085-1091
-
-
Handa, T.1
Ishihara, H.2
Ohshima, H.3
-
28
-
-
0034914543
-
Regional variations in certain cellular characteristics in human lumbar intervertebral discs, including the presence of α-smooth muscle actin
-
Hastreiter D, Ozuna RM, Spector M. 2001; Regional variations in certain cellular characteristics in human lumbar intervertebral discs, including the presence of α-smooth muscle actin. J Orthop Res 19: 597-604.
-
(2001)
J Orthop Res
, vol.19
, pp. 597-604
-
-
Hastreiter, D.1
Ozuna, R.M.2
Spector, M.3
-
29
-
-
38449113839
-
Regenerative treatment strategies in spinal surgery
-
Hegewald AA, Ringe J, Sittinger M, et al. 2008; Regenerative treatment strategies in spinal surgery. Front Biosci 13: 1507-1525.
-
(2008)
Front Biosci
, vol.13
, pp. 1507-1525
-
-
Hegewald, A.A.1
Ringe, J.2
Sittinger, M.3
-
30
-
-
79551696997
-
Adequacy of herniated disc tissue as a cell source for nucleus pulposus regeneration
-
Hegewald AA, Endres M, Abbushi A, et al. 2011a; Adequacy of herniated disc tissue as a cell source for nucleus pulposus regeneration. J Neurosurg Spine 14: 273-280.
-
(2011)
J Neurosurg Spine
, vol.14
, pp. 273-280
-
-
Hegewald, A.A.1
Endres, M.2
Abbushi, A.3
-
31
-
-
79952752332
-
Engineering of polymer-based grafts with cells derived from human nucleus pulposus tissue of the lumbar spine
-
Hegewald AA, Enz A, Endres M, et al. 2011b; Engineering of polymer-based grafts with cells derived from human nucleus pulposus tissue of the lumbar spine. J Tissue Eng Regen Med 5: 275-282.
-
(2011)
J Tissue Eng Regen Med
, vol.5
, pp. 275-282
-
-
Hegewald, A.A.1
Enz, A.2
Endres, M.3
-
32
-
-
44849136816
-
Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc
-
Hoyland JA, Le Maitre C, Freemont AJ. 2008; Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc. Rheumatology (Oxf) 47: 809-814.
-
(2008)
Rheumatology (Oxf)
, vol.47
, pp. 809-814
-
-
Hoyland, J.A.1
Le Maitre, C.2
Freemont, A.J.3
-
33
-
-
34249043839
-
Recombinant human osteogenic protein-1 upregulates proteoglycan metabolism of human anulus fibrosus and nucleus pulposus cells
-
Imai Y, Miyamoto K, An HS, et al. 2007; Recombinant human osteogenic protein-1 upregulates proteoglycan metabolism of human anulus fibrosus and nucleus pulposus cells. Spine 32: 1303-1309.
-
(2007)
Spine
, vol.32
, pp. 1303-1309
-
-
Imai, Y.1
Miyamoto, K.2
An, H.S.3
-
34
-
-
0026008369
-
Histochemical and ultrastructural observations on brown degeneration of human intervertebral disc
-
Ishii T, Tsuji H, Sano A, et al. 1991; Histochemical and ultrastructural observations on brown degeneration of human intervertebral disc. J Orthop Res 9: 78-90.
-
(1991)
J Orthop Res
, vol.9
, pp. 78-90
-
-
Ishii, T.1
Tsuji, H.2
Sano, A.3
-
35
-
-
79954428570
-
TGFβ signaling plays an essential role in the growth and maintenance of intervertebral disc tissue
-
Jin H, Shen J, Wang B, et al. 2011; TGFβ signaling plays an essential role in the growth and maintenance of intervertebral disc tissue. FEBS Lett 585: 1209-1215.
-
(2011)
FEBS Lett
, vol.585
, pp. 1209-1215
-
-
Jin, H.1
Shen, J.2
Wang, B.3
-
37
-
-
57049099115
-
Tissue engineering and the intervertebral disc: the challenges
-
Kandel R, Roberts S, Urban JP. 2008; Tissue engineering and the intervertebral disc: the challenges. Eur Spine J 17(suppl 4): 480-491.
-
(2008)
Eur Spine J
, vol.17
, pp. 480-491
-
-
Kandel, R.1
Roberts, S.2
Urban, J.P.3
-
38
-
-
0030054279
-
Immunohistochemical study of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 human intervertebral discs
-
Kanemoto M, Hukuda S, Komiya Y, et al. 1996; Immunohistochemical study of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 human intervertebral discs. Spine 21: 1-8.
-
(1996)
Spine
, vol.21
, pp. 1-8
-
-
Kanemoto, M.1
Hukuda, S.2
Komiya, Y.3
-
39
-
-
41849145220
-
Fas ligand expression on human nucleus pulposus cells decreases with disc degeneration processes
-
Kaneyama S, Nishida K, Takada T, et al. 2008; Fas ligand expression on human nucleus pulposus cells decreases with disc degeneration processes. J Orthop Sci 13: 130-135.
-
(2008)
J Orthop Sci
, vol.13
, pp. 130-135
-
-
Kaneyama, S.1
Nishida, K.2
Takada, T.3
-
40
-
-
33645875892
-
Gene expression profiling of human articular cartilage grafts generated by tissue engineering
-
Kaps C, Frauenschuh S, Endres M, et al. 2006; Gene expression profiling of human articular cartilage grafts generated by tissue engineering. Biomaterials 27: 3617-3630.
-
(2006)
Biomaterials
, vol.27
, pp. 3617-3630
-
-
Kaps, C.1
Frauenschuh, S.2
Endres, M.3
-
41
-
-
0346120077
-
Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells
-
Kim DJ, Moon SH, Kim H, et al. 2003; Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells. Spine 28: 2679-2684.
-
(2003)
Spine
, vol.28
, pp. 2679-2684
-
-
Kim, D.J.1
Moon, S.H.2
Kim, H.3
-
42
-
-
27144470232
-
Human annulus fibrosis and nucleus pulposus cells of the intervertebral disc: effect of degeneration and culture system on cell phenotype
-
Kluba T, Niemeyer T, Gaissmaier C, et al. 2005; Human annulus fibrosis and nucleus pulposus cells of the intervertebral disc: effect of degeneration and culture system on cell phenotype. Spine 30: 2743-2748.
-
(2005)
Spine
, vol.30
, pp. 2743-2748
-
-
Kluba, T.1
Niemeyer, T.2
Gaissmaier, C.3
-
43
-
-
14344257216
-
The adeno-associated viral vector as a strategy for intradiscal gene transfer in immune competent and pre-exposed rabbits
-
Lattermann C, Oxner WM, Xiao X, et al. 2005; The adeno-associated viral vector as a strategy for intradiscal gene transfer in immune competent and pre-exposed rabbits. Spine 30: 497-504.
-
(2005)
Spine
, vol.30
, pp. 497-504
-
-
Lattermann, C.1
Oxner, W.M.2
Xiao, X.3
-
44
-
-
0035499460
-
New use of a three-dimensional pellet culture system for human intervertebral disc cells: initial characterization and potential use for tissue engineering
-
Lee JY, Hall R, Pelinkovic D, et al. 2001; New use of a three-dimensional pellet culture system for human intervertebral disc cells: initial characterization and potential use for tissue engineering. Spine 26: 2316-2322.
-
(2001)
Spine
, vol.26
, pp. 2316-2322
-
-
Lee, J.Y.1
Hall, R.2
Pelinkovic, D.3
-
45
-
-
29744447597
-
The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration
-
Le Maitre CL, Freemont AJ, Hoyland JA. 2005; The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration. Arthritis Res Ther 7: R732-745.
-
(2005)
Arthritis Res Ther
, vol.7
, pp. R732-R745
-
-
Le Maitre, C.L.1
Freemont, A.J.2
Hoyland, J.A.3
-
46
-
-
75649092677
-
Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells
-
Le Maitre CL, Freemont AJ, Hoyland JA. 2009; Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells. Arthritis Res Ther 11: R137.
-
(2009)
Arthritis Res Ther
, vol.11
, pp. R137
-
-
Le Maitre, C.L.1
Freemont, A.J.2
Hoyland, J.A.3
-
47
-
-
80053217103
-
Tissue engineering for intervertebral disk degeneration
-
Leung VY, Tam V, Chan D, et al. 2011; Tissue engineering for intervertebral disk degeneration. Orthop Clin North Am 42: 575-583.
-
(2011)
Orthop Clin North Am
, vol.42
, pp. 575-583
-
-
Leung, V.Y.1
Tam, V.2
Chan, D.3
-
48
-
-
33747366957
-
Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis
-
Le Visage C, Kim SW, Tateno K, et al. 2006a; Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis. Spine 31: 2036-2042.
-
(2006)
Spine
, vol.31
, pp. 2036-2042
-
-
Le Visage, C.1
Kim, S.W.2
Tateno, K.3
-
49
-
-
33749507436
-
Small intestinal submucosa as a potential bioscaffold for intervertebral disc regeneration
-
Le Visage C, Yang SH, Kadakia L, et al. 2006b; Small intestinal submucosa as a potential bioscaffold for intervertebral disc regeneration. Spine 31: 2423-2430.
-
(2006)
Spine
, vol.31
, pp. 2423-2430
-
-
Le Visage, C.1
Yang, S.H.2
Kadakia, L.3
-
50
-
-
79551556421
-
Age-related variation in cell density of human lumbar intervertebral discs
-
Liebscher T, Haefeli M, Wuertz K, et al. 2011; Age-related variation in cell density of human lumbar intervertebral discs. Spine 36: 153-159.
-
(2011)
Spine
, vol.36
, pp. 153-159
-
-
Liebscher, T.1
Haefeli, M.2
Wuertz, K.3
-
51
-
-
14844339516
-
Animal models of intervertebral disc degeneration: lessons learned
-
Lotz JC. 2004; Animal models of intervertebral disc degeneration: lessons learned. Spine 29: 2742-2750.
-
(2004)
Spine
, vol.29
, pp. 2742-2750
-
-
Lotz, J.C.1
-
52
-
-
0036147236
-
Toxicity of a first-generation adenoviral vector in rhesus macaques
-
Lozier JN, Csako G, Mondoro TH, et al. 2002; Toxicity of a first-generation adenoviral vector in rhesus macaques. Hum Gene Ther 13: 113-124.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 113-124
-
-
Lozier, J.N.1
Csako, G.2
Mondoro, T.H.3
-
53
-
-
0037151084
-
Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage
-
Malfait AM, Liu RQ, Ijiri K, et al. 2002; Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage. J Biol Chem 277: 22201-22208.
-
(2002)
J Biol Chem
, vol.277
, pp. 22201-22208
-
-
Malfait, A.M.1
Liu, R.Q.2
Ijiri, K.3
-
54
-
-
0016752270
-
Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro
-
Maroudas A, Stockwell RA, Nachemson A, et al. 1975; Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro. J Anat 120: 113-130.
-
(1975)
J Anat
, vol.120
, pp. 113-130
-
-
Maroudas, A.1
Stockwell, R.A.2
Nachemson, A.3
-
55
-
-
14844350606
-
Growth factors and treatment of intervertebral disc degeneration
-
Masuda K, Oegema TR, An HS. 2004; Growth factors and treatment of intervertebral disc degeneration. Spine 29: 2757-2769.
-
(2004)
Spine
, vol.29
, pp. 2757-2769
-
-
Masuda, K.1
Oegema, T.R.2
An, H.S.3
-
56
-
-
73449118585
-
Cell-seeded polyurethane-fibrin structures - a possible system for intervertebral disc regeneration
-
discussion, 38-39.
-
Mauth C, Bono E, Haas S, et al. 2009; Cell-seeded polyurethane-fibrin structures - a possible system for intervertebral disc regeneration. Eur Cell Mater 18: 27-38; discussion, 38-39.
-
(2009)
Eur Cell Mater
, vol.18
, pp. 27-38
-
-
Mauth, C.1
Bono, E.2
Haas, S.3
-
57
-
-
0035080357
-
Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12
-
Mazzolini G, Narvaiza I, Pérez-Diez A, et al. 2001; Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12. Gene Ther 8: 259-267.
-
(2001)
Gene Ther
, vol.8
, pp. 259-267
-
-
Mazzolini, G.1
Narvaiza, I.2
Pérez-Diez, A.3
-
58
-
-
0029907896
-
In vivo stress measurement can predict pain on discography
-
McNally DS, Shackleford IM, Goodship AE, et al. 1996; In vivo stress measurement can predict pain on discography. Spine 21: 2580-2587.
-
(1996)
Spine
, vol.21
, pp. 2580-2587
-
-
McNally, D.S.1
Shackleford, I.M.2
Goodship, A.E.3
-
59
-
-
33748564336
-
Clinical experience in cell-based therapeutics: intervention and outcome
-
Meisel HJ, Ganey T, Hutton WC, et al. 2006; Clinical experience in cell-based therapeutics: intervention and outcome. Eur Spine J 15(suppl 3): 397-405.
-
(2006)
Eur Spine J
, vol.15
, pp. 397-405
-
-
Meisel, H.J.1
Ganey, T.2
Hutton, W.C.3
-
60
-
-
57649206549
-
Biologic response of human intervertebral disc cells to gene therapy cocktail
-
Moon SH, Nishida K, Gilbertson LG, et al. 2008; Biologic response of human intervertebral disc cells to gene therapy cocktail. Spine 33: 1850-1855.
-
(2008)
Spine
, vol.33
, pp. 1850-1855
-
-
Moon, S.H.1
Nishida, K.2
Gilbertson, L.G.3
-
61
-
-
33645230161
-
Pathophysiology of disk-related sciatica. I. Evidence supporting a chemical component
-
Mulleman D, Mammou S, Griffoul I, et al. 2006; Pathophysiology of disk-related sciatica. I. Evidence supporting a chemical component. Joint Bone Spine 73: 151-158.
-
(2006)
Joint Bone Spine
, vol.73
, pp. 151-158
-
-
Mulleman, D.1
Mammou, S.2
Griffoul, I.3
-
62
-
-
35148882630
-
Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage
-
Naito S, Shiomi T, Okada A, et al. 2007; Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage. Pathol Int 57: 703-711.
-
(2007)
Pathol Int
, vol.57
, pp. 703-711
-
-
Naito, S.1
Shiomi, T.2
Okada, A.3
-
63
-
-
81555201507
-
Interactions of environmental conditions and mechanical loads have influence on matrix turnover by nucleus pulposus cells
-
Neidlinger-Wilke C, Mietsch A, Rinkler C, et al. 2012; Interactions of environmental conditions and mechanical loads have influence on matrix turnover by nucleus pulposus cells. J Orthop Res 30: 112-121.
-
(2012)
J Orthop Res
, vol.30
, pp. 112-121
-
-
Neidlinger-Wilke, C.1
Mietsch, A.2
Rinkler, C.3
-
64
-
-
19044398938
-
A three-dimensional collagen matrix as a suitable culture system for the comparison of cyclic strain and hydrostatic pressure effects on intervertebral disc cells
-
Neidlinger-Wilke C, Würtz K, Liedert A, et al. 2005; A three-dimensional collagen matrix as a suitable culture system for the comparison of cyclic strain and hydrostatic pressure effects on intervertebral disc cells. J Neurosurg Spine 2: 457-465.
-
(2005)
J Neurosurg Spine
, vol.2
, pp. 457-465
-
-
Neidlinger-Wilke, C.1
Würtz, K.2
Liedert, A.3
-
65
-
-
0034990761
-
Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity
-
Nemunaitis J, Cunningham C, Buchanan A, et al. 2001; Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity. Gene Ther 8: 746-759.
-
(2001)
Gene Ther
, vol.8
, pp. 746-759
-
-
Nemunaitis, J.1
Cunningham, C.2
Buchanan, A.3
-
66
-
-
45249104205
-
Cell encapsulation in biodegradable hydrogels for tissue engineering applications
-
Nicodemus GD, Bryant SJ. 2008; Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue Eng Part B Rev 14: 149-165.
-
(2008)
Tissue Eng Part B Rev
, vol.14
, pp. 149-165
-
-
Nicodemus, G.D.1
Bryant, S.J.2
-
67
-
-
0033404813
-
Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor-β1 encoding gene
-
Nishida K, Kang JD, Gilbertson LG, et al. 1999; Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor-β1 encoding gene. Spine 24: 2419-2425.
-
(1999)
Spine
, vol.24
, pp. 2419-2425
-
-
Nishida, K.1
Kang, J.D.2
Gilbertson, L.G.3
-
68
-
-
33745111263
-
Sustained transgene expression in intervertebral disc cells in vivo mediated by microbubble-enhanced ultrasound gene therapy
-
Nishida K, Doita M, Takada T, et al. 2006; Sustained transgene expression in intervertebral disc cells in vivo mediated by microbubble-enhanced ultrasound gene therapy. Spine 31: 1415-1419.
-
(2006)
Spine
, vol.31
, pp. 1415-1419
-
-
Nishida, K.1
Doita, M.2
Takada, T.3
-
69
-
-
0034909033
-
Nucleus pulposus allograft retards intervertebral disc degeneration
-
Nomura T, Mochida J, Okuma M, et al. 2001; Nucleus pulposus allograft retards intervertebral disc degeneration. Clin Orthop Relat Res 389: 94-101.
-
(2001)
Clin Orthop Relat Res
, vol.389
, pp. 94-101
-
-
Nomura, T.1
Mochida, J.2
Okuma, M.3
-
70
-
-
0026700749
-
The effect of lactate and pH on proteoglycan and protein synthesis rates in the intervertebral disc
-
Ohshima H, Urban JP. 1992; The effect of lactate and pH on proteoglycan and protein synthesis rates in the intervertebral disc. Spine 17: 1079-1082.
-
(1992)
Spine
, vol.17
, pp. 1079-1082
-
-
Ohshima, H.1
Urban, J.P.2
-
71
-
-
0034319143
-
Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: an in vitro and in vivo experimental study
-
Okuma M, Mochida J, Nishimura K, et al. 2000; Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: an in vitro and in vivo experimental study. J Orthop Res 18: 988-997.
-
(2000)
J Orthop Res
, vol.18
, pp. 988-997
-
-
Okuma, M.1
Mochida, J.2
Nishimura, K.3
-
72
-
-
0021742933
-
Effects of disc injury on mechanical behavior of the human spine
-
Panjabi MM, Krag MH, Chung TQ. 1984; Effects of disc injury on mechanical behavior of the human spine. Spine 9: 707-713.
-
(1984)
Spine
, vol.9
, pp. 707-713
-
-
Panjabi, M.M.1
Krag, M.H.2
Chung, T.Q.3
-
73
-
-
0038722197
-
Clinical spinal instability and low back pain
-
Panjabi MM. 2003; Clinical spinal instability and low back pain. J Electromyogr Kinesiol 13: 371-379.
-
(2003)
J Electromyogr Kinesiol
, vol.13
, pp. 371-379
-
-
Panjabi, M.M.1
-
74
-
-
12444288052
-
The pathogenesis of discogenic low back pain
-
Peng B, Wu W, Hou S, et al. 2005; The pathogenesis of discogenic low back pain. J Bone Joint Surg Br 87: 62-67.
-
(2005)
J Bone Joint Surg Br
, vol.87
, pp. 62-67
-
-
Peng, B.1
Wu, W.2
Hou, S.3
-
75
-
-
0033515827
-
Multilineage potential of adult human mesenchymal stem cells
-
Pittenger MF, Mackay AM, Beck SC, et al. 1999; Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147.
-
(1999)
Science
, vol.284
, pp. 143-147
-
-
Pittenger, M.F.1
Mackay, A.M.2
Beck, S.C.3
-
76
-
-
23944445287
-
Quantitation of collagen I, collagen II and aggrecan mRNA and expression of the corresponding proteins in human nucleus pulposus cells in monolayer cultures
-
Preradovic A, Kleinpeter G, Feichtinger H, et al. 2005; Quantitation of collagen I, collagen II and aggrecan mRNA and expression of the corresponding proteins in human nucleus pulposus cells in monolayer cultures. Cell Tissues Res 321: 459-464.
-
(2005)
Cell Tissues Res
, vol.321
, pp. 459-464
-
-
Preradovic, A.1
Kleinpeter, G.2
Feichtinger, H.3
-
77
-
-
33745002760
-
Intervertebral disc cell-mediated mesenchymal stem cell differentiation
-
Richardson SM, Walker RV, Parker S, et al. 2006; Intervertebral disc cell-mediated mesenchymal stem cell differentiation. Stem Cells 24: 707-716.
-
(2006)
Stem Cells
, vol.24
, pp. 707-716
-
-
Richardson, S.M.1
Walker, R.V.2
Parker, S.3
-
79
-
-
0034406875
-
Matrix metalloproteinases and aggrecanase: their role in disorders of the human intervertebral disc
-
Roberts S, Caterson B, Menage J, et al. 2000; Matrix metalloproteinases and aggrecanase: their role in disorders of the human intervertebral disc. Spine 25: 3005-3013.
-
(2000)
Spine
, vol.25
, pp. 3005-3013
-
-
Roberts, S.1
Caterson, B.2
Menage, J.3
-
80
-
-
33748521288
-
Senescence in human intervertebral discs
-
Roberts S, Evans EH, Kletsas D, et al. 2006; Senescence in human intervertebral discs. Eur Spine J 15(suppl 3): S312-316.
-
(2006)
Eur Spine J
, vol.15
, pp. S312-S316
-
-
Roberts, S.1
Evans, E.H.2
Kletsas, D.3
-
81
-
-
14844362345
-
Biology of intervertebral disc aging and degeneration: involvement of the extracellular matrix
-
Roughley PJ. 2004; Biology of intervertebral disc aging and degeneration: involvement of the extracellular matrix. Spine 29: 2691-2699.
-
(2004)
Spine
, vol.29
, pp. 2691-2699
-
-
Roughley, P.J.1
-
82
-
-
77952509160
-
Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model
-
Seki S, Asanuma-Abe Y, Masuda K, et al. 2009; Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model. Arthritis Res Ther 11: R166.
-
(2009)
Arthritis Res Ther
, vol.11
, pp. R166
-
-
Seki, S.1
Asanuma-Abe, Y.2
Masuda, K.3
-
83
-
-
33645562104
-
Mechanobiology of the intervertebral disc and relevance to disc degeneration
-
Setton LA, Chen J. 2006; Mechanobiology of the intervertebral disc and relevance to disc degeneration. J Bone Joint Surg Am 88(suppl 2): 52-57.
-
(2006)
J Bone Joint Surg Am
, vol.88
, pp. 52-57
-
-
Setton, L.A.1
Chen, J.2
-
84
-
-
77950424020
-
Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc
-
Sohn P, Cox M, Chen D, et al. 2010; Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc. BMC Dev Biol 10: 29.
-
(2010)
BMC Dev Biol
, vol.10
, pp. 29
-
-
Sohn, P.1
Cox, M.2
Chen, D.3
-
85
-
-
1442329076
-
Human intervertebral disc cell culture for disc disorders
-
Stern S, Lindenhayn K, Perka C. 2004; Human intervertebral disc cell culture for disc disorders. Clin Orthop Relat Res 419: 238-244.
-
(2004)
Clin Orthop Relat Res
, vol.419
, pp. 238-244
-
-
Stern, S.1
Lindenhayn, K.2
Perka, C.3
-
86
-
-
77957559989
-
Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype
-
Strassburg S, Richardson SM, Freemont AJ, et al. 2010; Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype. Regen Med 5: 701-711.
-
(2010)
Regen Med
, vol.5
, pp. 701-711
-
-
Strassburg, S.1
Richardson, S.M.2
Freemont, A.J.3
-
87
-
-
0017588293
-
Nutrition of the intervertebral disk. An in vivo study of solute transport
-
Urban JP, Holm S, Maroudas A, et al. 1977; Nutrition of the intervertebral disk. An in vivo study of solute transport. Clin Orthop Relat Res 129: 101-114.
-
(1977)
Clin Orthop Relat Res
, vol.129
, pp. 101-114
-
-
Urban, J.P.1
Holm, S.2
Maroudas, A.3
-
88
-
-
0023890833
-
Swelling pressure of the lumbar intervertebral discs: influence of age, spinal level, composition, and degeneration
-
Urban JP, McMullin JF. 1988; Swelling pressure of the lumbar intervertebral discs: influence of age, spinal level, composition, and degeneration. Spine 13: 179-187.
-
(1988)
Spine
, vol.13
, pp. 179-187
-
-
Urban, J.P.1
McMullin, J.F.2
-
89
-
-
14844342946
-
Nutrition of the intervertebral disc
-
Urban JP, Smith S, Fairbank JC. 2004; Nutrition of the intervertebral disc. Spine 29: 2700-2709.
-
(2004)
Spine
, vol.29
, pp. 2700-2709
-
-
Urban, J.P.1
Smith, S.2
Fairbank, J.C.3
-
90
-
-
34249908639
-
Regulation of transgene expression using an inducible system for improved safety of intervertebral disc gene therapy
-
Vadalà G, Sowa GA, Smith L, et al. 2007; Regulation of transgene expression using an inducible system for improved safety of intervertebral disc gene therapy. Spine 32: 1381-1387.
-
(2007)
Spine
, vol.32
, pp. 1381-1387
-
-
Vadalà, G.1
Sowa, G.A.2
Smith, L.3
-
91
-
-
42149144702
-
Coculture of bone marrow mesenchymal stem cells and nucleus pulposus cells modulate gene expression profile without cell fusion
-
Vadalà G, Studer RK, Sowa G, et al. 2008; Coculture of bone marrow mesenchymal stem cells and nucleus pulposus cells modulate gene expression profile without cell fusion. Spine 33: 870-876.
-
(2008)
Spine
, vol.33
, pp. 870-876
-
-
Vadalà, G.1
Studer, R.K.2
Sowa, G.3
-
92
-
-
0028910150
-
The long-term effects of physical loading and exercise lifestyles on back-related symptoms, disability, and spinal pathology among men
-
Videman T, Sarna S, Battié MC, et al. 1995; The long-term effects of physical loading and exercise lifestyles on back-related symptoms, disability, and spinal pathology among men. Spine 20: 699-709.
-
(1995)
Spine
, vol.20
, pp. 699-709
-
-
Videman, T.1
Sarna, S.2
Battié, M.C.3
-
93
-
-
0142023955
-
Gene transfer of the catabolic inhibitor TIMP-1 increases measured proteoglycans in cells from degenerated human intervertebral discs
-
Wallach CJ, Sobajima S, Watanabe Y, et al. 2003; Gene transfer of the catabolic inhibitor TIMP-1 increases measured proteoglycans in cells from degenerated human intervertebral discs. Spine 28: 2331-2337.
-
(2003)
Spine
, vol.28
, pp. 2331-2337
-
-
Wallach, C.J.1
Sobajima, S.2
Watanabe, Y.3
-
94
-
-
33644619565
-
Safety assessment of intradiscal gene transfer: a pilot study
-
Wallach CJ, Kim JS, Sobajima S, et al. 2006; Safety assessment of intradiscal gene transfer: a pilot study. Spine J 6: 107-112.
-
(2006)
Spine J
, vol.6
, pp. 107-112
-
-
Wallach, C.J.1
Kim, J.S.2
Sobajima, S.3
-
95
-
-
53749101496
-
Effects of RNAi-mediated inhibition of aggrecanase-1 and aggrecanase-2 on rat costochondral chondrocytes in vitro
-
Wang ZH, Yang ZQ, He XJ, et al. 2008; Effects of RNAi-mediated inhibition of aggrecanase-1 and aggrecanase-2 on rat costochondral chondrocytes in vitro. Acta Pharmacol Sin 29: 1215-1226.
-
(2008)
Acta Pharmacol Sin
, vol.29
, pp. 1215-1226
-
-
Wang, Z.H.1
Yang, Z.Q.2
He, X.J.3
-
96
-
-
78149309670
-
Lentivirus-mediated knockdown of aggrecanase-1 and -2 promotes chondrocyte-engineered cartilage formation in vitro
-
Wang ZH, Yang ZQ, He XJ, et al. 2010; Lentivirus-mediated knockdown of aggrecanase-1 and -2 promotes chondrocyte-engineered cartilage formation in vitro. Biotechnol Bioeng 107: 730-736.
-
(2010)
Biotechnol Bioeng
, vol.107
, pp. 730-736
-
-
Wang, Z.H.1
Yang, Z.Q.2
He, X.J.3
-
97
-
-
77949820578
-
Human nucleus pulposus cells significantly enhanced biological properties in a co-culture system with direct cell-to-cell contact with autologous mesenchymal stem cells
-
Watanabe T, Sakai D, Yamamoto Y, et al. 2010; Human nucleus pulposus cells significantly enhanced biological properties in a co-culture system with direct cell-to-cell contact with autologous mesenchymal stem cells. J Orthop Res 28: 623-630.
-
(2010)
J Orthop Res
, vol.28
, pp. 623-630
-
-
Watanabe, T.1
Sakai, D.2
Yamamoto, Y.3
-
98
-
-
0024445960
-
Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity
-
West MD, Pereira-Smith OM, Smith JR. 1989; Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity. Exp Cell Res 184: 138-147.
-
(1989)
Exp Cell Res
, vol.184
, pp. 138-147
-
-
West, M.D.1
Pereira-Smith, O.M.2
Smith, J.R.3
-
99
-
-
21444447468
-
Gelatin/chondroitin-6-sulfate copolymer scaffold for culturing human nucleus pulposus cells in vitro with production of extracellular matrix
-
Yang SH, Chen PQ, Chen YF, et al. 2005a; Gelatin/chondroitin-6-sulfate copolymer scaffold for culturing human nucleus pulposus cells in vitro with production of extracellular matrix. J Biomed Mater Res B Appl Biomater 74: 488-494.
-
(2005)
J Biomed Mater Res B Appl Biomater
, vol.74
, pp. 488-494
-
-
Yang, S.H.1
Chen, P.Q.2
Chen, Y.F.3
-
100
-
-
33644839420
-
An in vitro study on regeneration of human nucleus pulposus by using gelatin/chondroitin-6-sulfate/hyaluronan tri-copolymer scaffold
-
Yang SH, Chen PQ, Chen YF, et al. 2005b; An in vitro study on regeneration of human nucleus pulposus by using gelatin/chondroitin-6-sulfate/hyaluronan tri-copolymer scaffold. Artif Organs 29: 806-814.
-
(2005)
Artif Organs
, vol.29
, pp. 806-814
-
-
Yang, S.H.1
Chen, P.Q.2
Chen, Y.F.3
-
101
-
-
37549000181
-
Three-dimensional culture of human nucleus pulposus cells in fibrin clot: comparisons on cellular proliferation and matrix synthesis with cells in alginate
-
Yang SH, Wu CC, Shih TT, et al. 2008a; Three-dimensional culture of human nucleus pulposus cells in fibrin clot: comparisons on cellular proliferation and matrix synthesis with cells in alginate. Artif Organs 32: 70-73.
-
(2008)
Artif Organs
, vol.32
, pp. 70-73
-
-
Yang, S.H.1
Wu, C.C.2
Shih, T.T.3
-
102
-
-
60549089615
-
In vitro study on interaction between human nucleus pulposus cells and mesenchymal stem cells through paracrine stimulation
-
Yang SH, Wu CC, Shih TT, et al. 2008b; In vitro study on interaction between human nucleus pulposus cells and mesenchymal stem cells through paracrine stimulation. Spine 33: 1951-1957.
-
(2008)
Spine
, vol.33
, pp. 1951-1957
-
-
Yang, S.H.1
Wu, C.C.2
Shih, T.T.3
-
103
-
-
73949120252
-
Influence of age-related degeneration on regenerative potential of human nucleus pulposus cells
-
Yang SH, Lin CC, Hu MH, et al. 2010; Influence of age-related degeneration on regenerative potential of human nucleus pulposus cells. J Orthop Res 28: 379-383.
-
(2010)
J Orthop Res
, vol.28
, pp. 379-383
-
-
Yang, S.H.1
Lin, C.C.2
Hu, M.H.3
-
104
-
-
0028328261
-
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
-
Yang Y, Nunes FA, Berencsi K, et al. 1994; Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl Acad Sci USA 91: 4407-4411.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4407-4411
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
-
105
-
-
68049117109
-
The fate of bovine bone marrow stromal cells in hydrogels: a comparison to nucleus pulposus cells and articular chondrocytes
-
Zeiter S, van der Werf M, Ito K. 2009; The fate of bovine bone marrow stromal cells in hydrogels: a comparison to nucleus pulposus cells and articular chondrocytes. J Tissue Eng Regen Med 3: 310-320.
-
(2009)
J Tissue Eng Regen Med
, vol.3
, pp. 310-320
-
-
Zeiter, S.1
van der Werf, M.2
Ito, K.3
|