Effects of RNAi-mediated inhibition of aggrecanase-1 and aggrecanase-2 on rat costochondral chondrocytes in vitro

Acta Pharmacologica Sinica

Volumn 29, Issue 10, 2008, Pages 1215-1226

  Wang, Zheng Hui ^a   Yang, Zhuang Qun ^a   He, Xi Jing ^a   Wang, Li ^a   Li, Li Xia ^a   Tu, Jun Bo ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Aggrecan; Aggrecanase; Chondrocyte; Extracellular matrix; RNAi

Indexed keywords

ADAM PROTEIN; AGGRECANASE; AGGRECANASE 1; AGGRECANASE 1 INHIBITOR; AGGRECANASE 2; AGGRECANASE 2 INHIBITOR; ALPHA 2 MACROGLOBULIN; COLLAGEN; INTERLEUKIN 1BETA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE ALLOGRAFT; CARTILAGE CELL; CARTILAGE DEGENERATION; CARTILAGE GRAFT; CARTILAGE MATRIX; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GRAFT REJECTION; IN VITRO STUDY; NONHUMAN; PHENOTYPE; PROTEIN DEFICIENCY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

ADAM PROTEINS; AGGRECANS; ALPHA-MACROGLOBULINS; ANIMALS; CHONDROCYTES; COLLAGEN TYPE II; INTERLEUKIN-1BETA; PLASMIDS; PROCOLLAGEN N-ENDOPEPTIDASE; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; TRANSFECTION;

EID: 53749101496     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00856.x     Document Type: Article

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