Safety assessment of intradiscal gene transfer: A pilot study

Spine Journal

Volumn 6, Issue 2, 2006, Pages 107-112

  Wallach, Corey J ^a   Kim, Joseph S ^a   Sobajima, Satoshi ^a   Lattermann, Christian ^a   Oxner, William M ^a   McFadden, Karthryn ^b   Robbins, Paul D ^b   Gilbertson, Lars G ^a   Kang, James D ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Bone morphogenic protein 2; Degenerative disc disease; Gene therapy; Transforming growth factor 1

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COMPLEMENTARY DNA; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA1;

ADENOVIRUS VECTOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL MODEL; GENE DELIVERY SYSTEM; GENE TRANSFER; HEMIPLEGIA; HISTOPATHOLOGY; IN VIVO STUDY; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; NEUROLOGIC DISEASE; NONHUMAN; PILOT STUDY; PRIORITY JOURNAL; RABBIT; RISK BENEFIT ANALYSIS; SAFETY; SPINAL CORD;

ADENOVIRIDAE; ANIMALS; BONE MORPHOGENETIC PROTEINS; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; INJECTIONS, SPINAL; INTERVERTEBRAL DISK; MODELS, ANIMAL; PILOT PROJECTS; RABBITS; RECOMBINANT PROTEINS; SPINAL CORD; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33644619565     PISSN: 15299430     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spinee.2005.05.002     Document Type: Article

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