Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype

Regenerative Medicine

Volumn 5, Issue 5, 2010, Pages 701-711

  Strassburg, Sandra ^a   Richardson, Stephen M ^a   Freemont, Anthony J ^a   Hoyland, Judith A ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

co culture; intervertebral disc regeneration; mesenchymal stem cells; nucleus pulposus

Indexed keywords

AGGRECAN; COLLAGEN TYPE 6; CONNECTIVE TISSUE GROWTH FACTOR; GROWTH DIFFERENTIATION FACTOR 5; SOMATOMEDIN C; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; VERSICAN;

ADULT; AGED; ARTICLE; CELL CONTACT; CELL DIFFERENTIATION; CELL INTERACTION; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; LUMBAR SPINE; MALE; MESENCHYMAL STEM CELL; MONOLAYER CULTURE; NERVE CELL DEGENERATION; NEUROMODULATION; NUCLEUS PULPOSUS; PHENOTYPE; PRIORITY JOURNAL; TISSUE REPAIR; UPREGULATION;

CELL COMMUNICATION; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; HUMANS; INTERVERTEBRAL DISK; MESENCHYMAL STEM CELLS; PHENOTYPE; REGENERATIVE MEDICINE;

EID: 77957559989     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.10.59     Document Type: Article

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