Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: An in vivo study of adenovirus-mediated transfer of the human transforming growth factor β1 encoding gene

Spine

Volumn 24, Issue 23, 1999, Pages 2419-2425

  Nishida, Kotaro ^a   Kang, James D ^a   Gilbertson, Lars G ^a   Moon, Seong Hwan ^a   Suh, Jun Kyo ^a   Vogt, Molly T ^a   Robbins, Paul D ^b   Evans, Christopher H ^c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Adenovirus; Degenerative disc disease; Gene therapy; Growth factors; Transforming growth factor beta 1 (TGF 1)

Indexed keywords

COMPLEMENTARY DNA; LUCIFERASE; PROTEOGLYCAN; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA1;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE THERAPY; GENE TRANSFER; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INTERVERTEBRAL DISK DEGENERATION; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEOGLYCAN SYNTHESIS; RABBIT;

ADENOVIRIDAE; ANIMALS; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISK; PROTEOGLYCANS; RABBITS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033404813     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-199912010-00002     Document Type: Article

References (49)

1. Acsadi G, Dickson G, Love DR, et al. Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs. Nature 1991;352: 815-8.
2. Adler JH, Schoenbaum M, Silberberg R. Early onset of disk degeneration and spondylosis in sand rats (Psammomys obesus). Vet Pathol 1983;20:13-22.
3. Boden SD, Schimandle JH, Hutton WC. 1995 Volvo Award in basic sciences: The use of an osteoinductive growth factor for lumbar spinal fusion: Part II. Study of dose, carrier, and species. Spine 1995;20:2633-44.
4. Boden SD, Schimandle JH, Hutton WC, Chen MI. 1995 Volvo Award in basic sciences: The use of an osteoinductive growth factor for lumbar spinal fusion: Part I. Biology of spinal fusion. Spine 1995;20:2626-32.
5. Borenstein D. Epidemiology, etiology, diagnostic evaluation, and treatment of low back pain. Curr Opin Rheumatol 1992;4:226-32.
6. Bradford DS, Cooper KM, Oegema TR Jr. Chymopapain, chemonucleolysis, and nucleus pulposus regeneration. J Bone Joint Surg [Am] 1983;65: 1220-31.
7. Brown GL, Curtsinger LJ, White M, et al. Acceleration of tensile strength of incisions treated with EGF and TGF-β. Ann Surg 1988;208:788-94.
8. Buckwalter JA. Aging and degeneration of the human intervertebral disc. Spine 1995;20:1307-14.
9. Butler D, Trafimow JH, Andersson GB, McNeill TW, Huckman MS. Discs degenerate before facets. Spine 1990;15:111-13.
10. Diamant B, Karlsson J, Nachemson A. Correlation between lactate levels and pH in discs of patients with lumbar rhizopathies. Experientia 1968;24:1195-6.
11. Evans CH, Robbins PD. Possible orthopaedic applications of gene therapy. J Bone Joint Surg [Am] 1995;77:1103-14.
12. Evans CH, Robbins PD. Progress toward the treatment of arthritis by gene therapy. Ann Med 1995;27:543-6.
13. Gerich TG, Kang R, Fu FH, Robbins PD, Evans CH. Gene transfer to the rabbit patellar tendon: Potential for genetic enhancement of tendon and ligament healing. Gene Ther 1996;3:1089-93.
14. Graham FL, van der Eb AJ. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973;52:456-67.
15. Greenberg SN, Bello RP. The work hardening program and subsequent return to work of a client with low back pain. J Orthop Sports Phys Ther 1996;24: 37-45.
16. Hilibrand AS, Carlson GD, Palumbo MA, Jones PK, Bohlman HH. Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. J Bone Joint Surg [Am] 1999;81:519-28.
17. Hirsch C, Schajowicz F. Studies on structural changes in the lumbar annulus fibrosus. Acta Orthop Scand 1953;22:184-231.
18. Holm S, Maroudas A, Urban JP, Selstam G, Nachemson A. Nutrition of the intervertebral disc: Solute transport and metabolism. Connect Tissue Res 1981; 8:101-19.
19. Kang R, Marui T, Ghivizzani SC, et al. Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: A feasibility study. Osteoarthritis Cartilage 1997;5:139-43.
20. Kraemer J. Natural course and prognosis of intervertebral disc diseases. Spine 1995;20:635-9.
21. Lee CK. Accelerated degeneration of the segment adjacent to a lumbar fusion. Spine 1988;13:375-7.
22. Lipson SJ, Muir H. 1980 Volvo Award in basic science: Proteoglycans in experimental intervertebral disc degeneration. Spine 1981;6:194-210.
23. Lou J, Manske PR, Aoki M, Joyce ME. Adenovirus-mediated gene transfer into tendon and tendon sheath. J Orthop Res 1996;14:513-7.
24. MacDonald MJ, Sorock GS, Volinn E, Hashemi L, Clancy EA, Webster B. A descriptive study of recurrent low back pain claims. J Occup Environ Med 1997; 39:35-43.
25. Makarov SS, Olsen JC, Johnston WN, et al. Retrovirus-mediated in vivo gene transfer to synovium in bacterial cell wall-induced arthritis in rats. Gene Ther 1995;2:424-8.
26. 35S-labeled proteoglycans complexed to alcian blue by rapid filtration in multiwell plates. Analytical Biochem 1994;217:167-75.
27. Mittereder N, March KL, Trapnell BC. Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J Virol 1996;70:7498-509.
28. Nachemson A. Intradiscal measurements of pH in patients with lumbar rhizopathies. Acta Orthop Scand 1969;40:23-42.
29. Nakamura N, Shino K, Natsuume T, et al. Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament. Gene Ther 1998;5:1165-70.
30. Nishida K, Kang JD, Suh JK, Robbins PD, Evans CH, Gilbertson LG. Adenovirus-mediated gene transfer to nucleus pulposus cells: Implications for the treatment of intervertebral disc degeneration. Spine 1998;23:2437-43.
31. Osada R, Ohshima H, Ishihara H, et al. Autocrine/paracrine mechanism of insulin-like growth factor-1 secretion, and the effect of insulin-like growth factor-1 on proteoglycan synthesis in bovine intervertebral discs. J Orthop Res 1996;14:690-9.
32. Pearce RH, Grimmer BJ, Adams ME. Degeneration and the chemical composition of the human lumbar intervertebral disc. J Orthop Res 1987;5: 198-205.
33. Pelletier JP, Caron JP, Evans C, et al. In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy. Arthritis Rheum 1997;40:1012-9.
34. Puolakkainen PA, Twardzik DR, Ranchalis JE, Pankey SC, Reed MJ, Gombotz WR. The enhancement in wound healing by transforming growth factor-β1 (TGF-β1) depends on the topical delivery system. J Surg Res 1995;58:321-9.
35. Roberts AB, Sporn MB. Physiological actions and clinical applications of transforming growth factor-beta (TGF-β). Growth Factors 1993;8:1-9.
36. Roessler BJ, Allen ED, Wilson JM, Hartman JW, Davidson BL. Adenoviral-mediated gene transfer to rabbit synovium in vivo. J Clin Invest 1993; 92:1085-92.
37. Silberberg R, Aufdermaur M, Adler JH. Degeneration of the intervertebral disks and spondylosis in aging sand rats. Arch Pathol Lab Med 1979; 103:231-5.
38. Silcox DHr, Boden SD, Schimandle JH, Johnson P, Whitesides TE, Hutton WC. Reversing the inhibitory effect of nicotine on spinal fusion using an osteoinductive protein extract. Spine 1998;23:291-6; discussion 7.
39. Sporn MB, Roberts AB. Transforming growth factor-beta: Recent progress and new challenges. J Cell Biol 1992;119:1017-21.
40. Sporn MB, Roberts AB, Wakefield LM, de Crombrugghe B. Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol 1987;105:1039-45.
41. Sprugel KH, McPherson JM, Clowes AW, Ross R. Effects of growth factors in vivo: I. Cell ingrowth into porous subcutaneous chambers. Am J Pathol 1987; 129:601-3.
42. Thompson JP, Oegema TR Jr, Bradford DS. Stimulation of mature canine intervertebral disc by growth factors. Spine 1991;16:253-60.
43. Urban JP, McMullin JF. Swelling pressure of the invertebral disc: Influence of proteoglycan and collagen contents. Biorheology 1985;22:145-57.
44. Urban JP, McMullin JF. Swelling pressure of the lumbar intervertebral discs: Influence of age, spinal level, composition, and degeneration. Spine 1988;13: 179-87.
45. Vitadello M, Schiaffino MV, Picard A, Scarpa M, Schiaffino S. Gene transfer in regenerating muscle. Hum Gene Ther 1994;5:11-18.
46. Waddell G. Low back pain: A twentieth-century health care enigma. Spine 1996;21:2820-5.
47. Wakefield LM, Winokur TS, Hollands RS, Christopherson K, Levinson AD, Sporn MB. Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution. J Clin Invest 1990;86:1976-84.
48. Webster BS, Snook SH. The cost of 1989 workers' compensation low back pain claims. Spine 1994;19:1111-15; discussion 6.
49. Yeh P, Perricaudet M. Advances in adenoviral vectors: From genetic engineering to their biology. FASEB J 1997;11:615-23.