AM404 inhibits NFAT and NF-κB signaling pathways and impairs migration and invasiveness of neuroblastoma cells

European Journal of Pharmacology

Volumn 746, Issue , 2015, Pages 221-232

  Caballero, Francisco J ^a   Soler Torronteras, Rafael ^a   Lara Chica, Maribel ^a   García, Victor ^a   Fiebich, Bernd L ^b   Muñoz, Eduardo ^a   Calzado, Marco A ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Acetaminophen; AM404; COX 2; Neuroblastoma; NFAT; Tpl2 Cot kinase

Indexed keywords

ANANDAMIDE; ARVANIL; CYCLOOXYGENASE 2; DOPAMINE; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERSTITIAL COLLAGENASE; MATRILYSIN; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; N ARACHIDONOYL DOPAMINE; PROSTAGLANDIN E2; STROMELYSIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; ARACHIDONIC ACID DERIVATIVE; HYBRID PROTEIN; N-(4-HYDROXYPHENYL)ARACHIDONYLAMIDE; NERVE PROTEIN; PTGS2 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL INVASION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MIGRATION INHIBITION; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL MOTION; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEOPLASM INVASIVENESS; NERVE CELL; NEUROBLASTOMA; PATHOLOGY; PROMOTER REGION; REPORTER GENE; TUMOR CELL LINE;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ARACHIDONIC ACIDS; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; MICE; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; NEUROBLASTOMA; NEURONS; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 84919346760     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.11.023     Document Type: Article

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