Paracetamol (acetaminophen) penetrates readily into the cerebrospinal fluid of children after intravenous administration

Pediatrics

Volumn 119, Issue 4, 2007, Pages 766-771

  Kumpulainen, Elina ^a,b   Kokki, Hannu ^a,b,c   Halonen, Toivo ^b   Heikkinen, Marja ^b   Savolainen, Jouko ^a   Laisalmi, Merja ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c Department of Anesthesiology and Intensive Care ^*  (Finland)

Author keywords

Acetaminophen; Cerebrospinal fluid; Child; Infant; Paracetamol; Pharmacokinetics

Indexed keywords

FENTANYL; IBUPROFEN; KETOPROFEN; NAPROXEN; OXYCODONE; PARACETAMOL;

AGITATION; ARTICLE; BLOOD SAMPLING; CEREBROSPINAL FLUID; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG PENETRATION; FEMALE; FLUORESCENCE POLARIZATION IMMUNOASSAY; HUMAN; INFANT; MALE; NAUSEA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PROSPECTIVE STUDY; SHIVERING; SIDE EFFECT; SPINAL ANESTHESIA; VENOUS BLOOD; VOMITING;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANALYSIS OF VARIANCE; ANESTHESIA, SPINAL; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INJECTIONS, INTRAVENOUS; MALE; PROBABILITY; PROSPECTIVE STUDIES; REFERENCE VALUES; SPINAL PUNCTURE; SURGICAL PROCEDURES, OPERATIVE; TIME FACTORS;

EID: 34147123764     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2006-3378     Document Type: Article

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