Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation

Clinical and Experimental Metastasis

Volumn 26, Issue 5, 2009, Pages 425-432

  Kurihara, Yuji ^a   Hatori, Masashi ^a   Ando, Yuriko ^a   Ito, Daisuke ^a   Toyoshima, Takahiko ^a   Tanaka, Makoto ^a   Shintani, Satoru ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

COX 2; MMP 2; Squamous cell carcinoma; TIMP 2

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GELATINASE A; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANTISENSE THERAPY; ARTICLE; CANCER CELL CULTURE; CELL INVASION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; FIBROBLAST CULTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOUTH CANCER; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; COLLAGEN; CYCLOOXYGENASE 2 INHIBITORS; DOWN-REGULATION; DRUG COMBINATIONS; ENZYME ACTIVATION; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LAMININ; MATRIX METALLOPROTEINASE 2; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; PROTEOGLYCANS; TETRAZOLIUM SALTS; THIAZOLES; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 67349232801     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-009-9241-3     Document Type: Article

References (49)

1. CE Eberhart RN Dubois 1995 Eicosanoids and the gastrointestinal tract Gastroenterology 109 1 285 301 10.1016/0016-5085(95)90296-1
2. LJ Marnett 1992 Aspirin and the potential role of prostaglandins in colon cancer Cancer Res 52 20 5575 5589
3. T Hosoi K Takeda K Konno 1989 Synergism of prostaglandin E2 plus TNF in induction of differentiation of human monocytoid leukemic U-937 cells Anticancer Res 9 3 615 618 (Pubitemid 19194290)
4. HR Herschman 1996 Prostaglandin synthase 2 Biochim Biophys Acta 1299 1 125 140 (Pubitemid 126753554)
5. RN Dubois SB Abramson L Crofford 1998 Cyclooxygenase in biology and disease FASEB J 12 12 1063 1073 (Pubitemid 28418937)
6. CS Williams W Smalley RN Dubois 1997 Aspirin use and potential mechanisms for colorectal cancer prevention J Clin Investig 100 6 1325 1329 10.1172/JCI119651 (Pubitemid 27425755)
7. S Gupta M Srivastava N Ahmad 2000 Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma Prostate 42 1 73 78 10.1002/(SICI)1097- 0045(20000101)42:1<73::AID-PROS9>3.0.CO;2-G
8. H Wolff K Saukkonen S Anttila 1998 Expression of cyclooxygenase-2 in human lung carcinoma Cancer Res 58 22 4997 5001 (Pubitemid 28521147)
9. KC Zimmermann M Sarbia AA Weber 1999 Cyclooxygenase-2 expression in human esophageal carcinoma Cancer Res 59 1 198 204 (Pubitemid 29062978)
10. ON Tucker AJ Dannenberg EK Yang 1999 Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer Cancer Res 59 5 987 990 (Pubitemid 29135954)
11. G Chan JO Boyle EK Yang 1999 Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck Cancer Res 59 5 991 994 (Pubitemid 29135955)
12. JL Masferrer KM Leahy AT Koki 2000 Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors Cancer Res 60 5 1306 1311 (Pubitemid 30151999)
13. K Uefuji T Ichikura H Mochizuki 2000 Cyclooxygenase-2 expression is related to prostaglandin biosynthesis and angiogenesis in human gastric cancer Clin Cancer Res 6 1 135 138 (Pubitemid 30064985)
14. H Sato T Takino Y Okada 1994 A matrix metalloproteinase expressed on the surface of invasive tumour cells Nature 370 61 65 10.1038/370061a0
15. K Sumitani R Kamijo T Toyoshima 2001 Specific inhibition of cyclooxygenase-2 results in inhibition of proliferation of oral cancer cell lines via suppression of prostaglandin E2 production J Oral Pathol Med 30 1 41 47 10.1034/j.1600-0714.2001.300107.x
16. Y Kinugasa M Hatori 2004 Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44 Clin Exp Metastasis 21 737 745 10.1007/s10585-005-1190-x
17. DW Tang SC Lin KW Chang 2003 Elevated expression of cyclooxygenase (COX)-2 in oral squamous cell carcinoma-evidence for COX-2 induction by areca quid ingredients in oral keratinocytes J Oral Pathol Med 32 9 522 529 10.1034/j.1600-0714.2003.00182.x
18. X Tang YJ Sun E Half 2002 Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells Cancer Res 62 17 4903 4908
19. WK Leung KF To MY Go 2003 Cyclooxygenase-2 upregulates vascular endothelial growth factor expression and angiogenesis in human gastric carcinoma Int J Oncol 23 5 1317 1322
20. M Huang M Stolona S Sharma 1998 Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production Cancer Res 58 6 1208 1216 (Pubitemid 28183210)
21. S Abiru K Nakao T Ichikawa 2002 Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells Hepatology (Baltimore) 35 5 1117 1124 10.1053/jhep.2002.32676
22. TD Tisty 2001 Stromal cells can contribute oncogenic signals Semin Cancer Biol 11 97 104 10.1006/scbi.2000.0361
23. D Radisky C Hagios MJ Bissell 2001 Tumors are unique organs defined by abnormal signaling and context Semin Cancer Biol 11 87 95 10.1006/scbi.2000.0360
24. AM Che TH Jung JH Choi 2006 Collagen-based co-culture for invasive study on cancer cells-fibroblasts interaction Biochem Biophys Res Commun 346 268 275 10.1016/j.bbrc.2006.05.111
25. CJ Sympson Z Werb MJ Bissell 1995 Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1 Semin Cancer Biol 6 159 163 10.1006/scbi.1995.0022
26. MD Sternlicht A Lochter CJ Sympson 1999 The stromal proteinase MMP3/Stromelysin-1 promotes mammary carcinogenesis Cell 98 137 146 10.1016/S0092-8674(00)81009-0
27. UB Hofmann JR Westphal AJ Zendman 2000 Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type matrix metalloproteinase 1 (MT1-MMP) correlate with melanoma progression J Pathol 191 245 256 10.1002/1096-9896(2000)9999:9999<::AID-PATH632>3.0. CO;2-#
28. UB Hofmann AAO Eggert K Blass 2003 Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation Cancer Res 63 23 8221 8225 (Pubitemid 37549471)
29. J Westermarck V-M Kähäri 1999 Regulation of matrix metalloproteinase expression in tumor invasion FASEB J 13 781 792 (Pubitemid 29220691)
30. AF Chambers LM Matrisian 1997 Changing views of the role of matrix metalloproteinases in metastasis J Natl Cancer Inst 89 17 1260 1270 10.1093/jnci/89.17.1260 (Pubitemid 27371946)
31. C Yang M Zeisberg JC Lively 2003 Integrin alpha1beta1 and alpha2beta1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment Cancer Res 63 23 8312 8317 (Pubitemid 37549483)
32. CM Robinson AM Stone JD Shields 2003 Functional significance of MMP-2 and MMP-9 expression by human malignant oral keratinocyte cell lines Arch Oral Biol 48 11 779 786 10.1016/S0003-9969(03)00172-9
33. MM Bernardo R Fridman 2003 TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP Biochem J 374 739 745 10.1042/BJ20030557
34. FA Attiga PM Fernandez AT Weeraratna 2000 Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases Cancer Res 60 16 4629 4637 (Pubitemid 32103650)
35. T Sato M n Ovejero P Hou 1997 Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts J Cell Sci 110 5 589 596 (Pubitemid 27153973)
36. N Hiraoka E Allen IJ Apel 1998 Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins Cell 95 3 365 377 10.1016/S0092-8674(00)81768-7
37. M Seiki I Yana 2003 Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis Cancer Sci 94 7 569 574 10.1111/j.1349-7006.2003.tb01484.x
38. M Seiki 2003 Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion Cancer Lett 194 1 1 11 10.1016/S0304-3835(02)00699-7
39. V Knauper H Will C Lopez-Otin 1996 Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase (MMP-2) are able to generate active enzyme J Biochem 271 29 17124 17131 (Pubitemid 26244262)
40. K Brew K Kinakarpandian H Nagase 2000 Tissue inhibitors of metalloproteinases: evolution, structure, and function Biochim Biophys Acta 1477 267 283 (Pubitemid 30119906)
41. WG Stetler-Stevenson S Aznavoorian LA Liotta 1993 Tumor cell interactions with the extracellular matrix during invasion and metastasis Annu Rev Cell Biol 9 541 573 10.1146/annurev.cb.09.110193.002545 (Pubitemid 2021155)
42. T Sato M Iwai T Sakai 1999 Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts Br J Cancer 80 1137 1143 10.1038/sj.bjc.6690477
43. A Noël A Hajitou C L'Hoir 1998 Inhibition of stromal matrix metalloproteinases: effects on breast-tumor promotion by fibroblasts Int J Cancer 76 267 273 10.1002/(SICI)1097-0215(19980413)76:2<267::AID-IJC15>3. 0.CO;2-9
44. A Kruger OH Sanchez-Sweatman DC Martin 1998 Host TIMP-1 overexpression confers resistance to experimental brain metastasis of a fibrosarcoma cell line Oncogene 16 2419 2423 10.1038/sj.onc.1201774 (Pubitemid 28226891)
45. M Wang YE Liu S Greene 1997 Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4 Oncogene 14 2767 2774 10.1038/sj.onc.1201245
46. AH Baker SJ George AB Zaltsman G Murphy AC Newby 1999 Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3 Br J Cancer 79 1347 1355 10.1038/sj.bjc.6690217 (Pubitemid 29116789)
47. P Basset JP Bellocq C Wolf 1990 A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas Nature 348 699 704 10.1038/348699a0 (Pubitemid 120015135)
48. T Sorsa L Tjaderhane T Salo 2004 Matrix metalloproteinases (MMPs) in oral diseases Oral Dis 10 311 318 10.1111/j.1601-0825.2004.01038.x
49. A Okada JP Bellocq N Rouyer 1995 Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas Proc Natl Acad Sci USA 92 2730 2734 10.1073/pnas.92.7.2730