Fatty Acid Amide Hydrolase-Dependent Generation of Antinociceptive Drug Metabolites Acting on TRPV1 in the Brain

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Barrière, David A ^a,b   Mallet, Christophe ^a,b   Blomgren, Anders ^c   Simonsen, Charlotte ^c   Daulhac, Laurence ^a,b   Libert, Frédéric ^a,b   Chapuy, Eric ^a,b   Etienne, Monique ^a,b   Högestätt, Edward D ^c   Zygmunt, Peter M ^c   Eschalier, Alain ^a,b,d  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b Inserm U1107 Neuro Dol ^*  (France)

^c LUND UNIVERSITY   (Sweden)

^d SERVICE DE RHUMATOLOGIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPHENOL; 4 HYDROXY 3 METHOXYBENZYLAMINE; ANTINOCICEPTIVE AGENT; ARVANIL; CANNABINOID 1 RECEPTOR; CAPSAZEPINE; DRUG METABOLITE; FATTY ACID AMIDASE; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; N (4 HYDROXYPHENYL)OCTADECENAMIDE; OLVANIL; SEROTONIN 1A RECEPTOR; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MEGADOSE; DRUG POTENCY; DRUG STRUCTURE; DRUG TOLERABILITY; IMMERSION; LOW DRUG DOSE; MALE; MOUSE; NEUROTRANSMISSION; NONHUMAN; RAT; SEROTONINERGIC SYSTEM;

EID: 84881107053     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070690     Document Type: Article

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